RU2002111335A - ENVIRONMENT FOR CULTIVATION OF CELLS WITHOUT PROTEINS AND WITHOUT SERUM - Google Patents
ENVIRONMENT FOR CULTIVATION OF CELLS WITHOUT PROTEINS AND WITHOUT SERUMInfo
- Publication number
- RU2002111335A RU2002111335A RU2002111335/13A RU2002111335A RU2002111335A RU 2002111335 A RU2002111335 A RU 2002111335A RU 2002111335/13 A RU2002111335/13 A RU 2002111335/13A RU 2002111335 A RU2002111335 A RU 2002111335A RU 2002111335 A RU2002111335 A RU 2002111335A
- Authority
- RU
- Russia
- Prior art keywords
- medium
- cells
- soy hydrolyzate
- medium according
- protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title claims 7
- 108090000623 proteins and genes Proteins 0.000 title claims 7
- 210000002966 serum Anatomy 0.000 title 1
- 239000002609 medium Substances 0.000 claims 23
- 210000004027 cell Anatomy 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 4
- 210000004962 mammalian cell Anatomy 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 2
- 229940024606 amino acid Drugs 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 239000006143 cell culture medium Substances 0.000 claims 2
- 239000003381 stabilizer Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- PWKSKIMOESPYIA-UHFFFAOYSA-N 2-acetamido-3-sulfanylpropanoic acid Chemical compound CC(=O)NC(CS)C(O)=O PWKSKIMOESPYIA-UHFFFAOYSA-N 0.000 claims 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 1
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 claims 1
- 235000019393 L-cystine Nutrition 0.000 claims 1
- 239000004158 L-cystine Substances 0.000 claims 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 1
- 229930182816 L-glutamine Natural products 0.000 claims 1
- 229930182821 L-proline Natural products 0.000 claims 1
- 229960001230 asparagine Drugs 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 229960003067 cystine Drugs 0.000 claims 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 claims 1
- 239000002158 endotoxin Substances 0.000 claims 1
- 229960002743 glutamine Drugs 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 1
- 229960002429 proline Drugs 0.000 claims 1
- 238000001542 size-exclusion chromatography Methods 0.000 claims 1
- IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 claims 1
- 238000000108 ultra-filtration Methods 0.000 claims 1
Claims (16)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0165999A AT409379B (en) | 1999-06-02 | 1999-09-28 | MEDIUM FOR PROTEIN- AND SERUM-FREE CELL CULTURE |
ATA1659/99 | 1999-09-28 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2005123274A Division RU2380412C2 (en) | 1999-09-28 | 2000-09-27 | Medium that does not contain proteins and serums, and method of mammal cell cultivation in such medium |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2002111335A true RU2002111335A (en) | 2003-11-10 |
RU2266325C2 RU2266325C2 (en) | 2005-12-20 |
Family
ID=3518214
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2002111335A RU2266325C2 (en) | 1999-09-28 | 2000-09-27 | Cell cultivation medium without proteins and serum |
RU2005123274A RU2380412C2 (en) | 1999-09-28 | 2000-09-27 | Medium that does not contain proteins and serums, and method of mammal cell cultivation in such medium |
RU2009131610/10A RU2536244C2 (en) | 1999-09-28 | 2009-08-20 | Medium for cultivation of cells without proteins and serum |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2005123274A RU2380412C2 (en) | 1999-09-28 | 2000-09-27 | Medium that does not contain proteins and serums, and method of mammal cell cultivation in such medium |
RU2009131610/10A RU2536244C2 (en) | 1999-09-28 | 2009-08-20 | Medium for cultivation of cells without proteins and serum |
Country Status (21)
Country | Link |
---|---|
US (6) | US20030203448A1 (en) |
EP (1) | EP1220893B2 (en) |
JP (6) | JP5441288B2 (en) |
CN (2) | CN101173246B (en) |
AT (2) | AT409379B (en) |
AU (1) | AU780791B2 (en) |
CA (1) | CA2385299A1 (en) |
CY (1) | CY1106135T1 (en) |
CZ (1) | CZ305307B6 (en) |
DE (1) | DE60028989T3 (en) |
DK (1) | DK1220893T4 (en) |
ES (1) | ES2265991T5 (en) |
HU (1) | HU228210B1 (en) |
IL (4) | IL148642A0 (en) |
PL (1) | PL215234B1 (en) |
PT (1) | PT1220893E (en) |
RU (3) | RU2266325C2 (en) |
SI (1) | SI1220893T1 (en) |
SK (1) | SK288059B6 (en) |
TR (1) | TR200200757T2 (en) |
WO (1) | WO2001023527A1 (en) |
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