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RS20050380A - 3-amino piperidine derivatives and methods of manufacture - Google Patents

3-amino piperidine derivatives and methods of manufacture

Info

Publication number
RS20050380A
RS20050380A YUP-2005/0380A YUP20050380A RS20050380A RS 20050380 A RS20050380 A RS 20050380A YU P20050380 A YUP20050380 A YU P20050380A RS 20050380 A RS20050380 A RS 20050380A
Authority
RS
Serbia
Prior art keywords
methods
manufacture
piperidine derivatives
amino piperidine
processes
Prior art date
Application number
YUP-2005/0380A
Other languages
English (en)
Inventor
David Harold Brown Ripin
Original Assignee
Pfizer Products Inc.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc., filed Critical Pfizer Products Inc.,
Publication of RS20050380A publication Critical patent/RS20050380A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Ovaj pronalazak se odnosi na derivate 3-amino piperidina, njihove intermedijere i postupke proizvodnje. Kao takav prikazani pronalazak uključuju postupke pripremanja jedinjenja formula (Ia) i (Ib) gde R, R2, R3, R4, R4, i n su ovde definisani. Prikazani pronalazak se odnosi na jedinejnja korišćena u takvom postupku, kao i na jedinjenja pripremljena postupkom.
YUP-2005/0380A 2002-11-21 2003-11-10 3-amino piperidine derivatives and methods of manufacture RS20050380A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42832402P 2002-11-21 2002-11-21
PCT/IB2003/005151 WO2004046112A2 (en) 2002-11-21 2003-11-10 3-amino-piperidine derivatives and processes for their preparation

Publications (1)

Publication Number Publication Date
RS20050380A true RS20050380A (en) 2007-11-15

Family

ID=32326635

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2005/0380A RS20050380A (en) 2002-11-21 2003-11-10 3-amino piperidine derivatives and methods of manufacture

Country Status (14)

Country Link
US (1) US7084277B2 (sr)
EP (1) EP1572649A2 (sr)
JP (1) JP2006508976A (sr)
KR (2) KR100742012B1 (sr)
CN (2) CN101353321A (sr)
AU (1) AU2003278529A1 (sr)
BR (1) BR0316470A (sr)
CA (1) CA2506016C (sr)
MX (1) MXPA05005403A (sr)
PL (1) PL377791A1 (sr)
RS (1) RS20050380A (sr)
RU (2) RU2309147C9 (sr)
WO (1) WO2004046112A2 (sr)
ZA (1) ZA200504068B (sr)

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Also Published As

Publication number Publication date
CN101353321A (zh) 2009-01-28
PL377791A1 (pl) 2006-02-20
AU2003278529A1 (en) 2004-06-15
CA2506016A1 (en) 2004-06-03
ZA200504068B (en) 2006-08-30
US20040102627A1 (en) 2004-05-27
KR20050083905A (ko) 2005-08-26
WO2004046112A2 (en) 2004-06-03
BR0316470A (pt) 2005-10-11
MXPA05005403A (es) 2005-08-03
WO2004046112A3 (en) 2004-08-05
RU2309147C2 (ru) 2007-10-27
KR100742012B1 (ko) 2007-07-23
CA2506016C (en) 2009-03-17
KR100678800B1 (ko) 2007-02-05
KR20060116873A (ko) 2006-11-15
EP1572649A2 (en) 2005-09-14
CN1726192A (zh) 2006-01-25
JP2006508976A (ja) 2006-03-16
RU2007116248A (ru) 2008-11-10
US7084277B2 (en) 2006-08-01
RU2309147C9 (ru) 2008-03-20
RU2005115500A (ru) 2006-01-20

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