RO91871B - Procedeu pentru prepararea unor derivati de 1,4-dihidro-4-oxonaftiridina - Google Patents
Procedeu pentru prepararea unor derivati de 1,4-dihidro-4-oxonaftiridinaInfo
- Publication number
- RO91871B RO91871B RO118517A RO11851785A RO91871B RO 91871 B RO91871 B RO 91871B RO 118517 A RO118517 A RO 118517A RO 11851785 A RO11851785 A RO 11851785A RO 91871 B RO91871 B RO 91871B
- Authority
- RO
- Romania
- Prior art keywords
- lower alkoxy
- alkoxy
- dihydro
- alkyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59084963A JPS60228479A (ja) | 1984-04-26 | 1984-04-26 | 1,4−ジヒドロ−4−オキソナフチリジン誘導体およびその塩 |
Publications (2)
Publication Number | Publication Date |
---|---|
RO91871A RO91871A (ro) | 1987-07-30 |
RO91871B true RO91871B (ro) | 1987-07-31 |
Family
ID=13845280
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO118517A RO91871B (ro) | 1984-04-26 | 1985-04-24 | Procedeu pentru prepararea unor derivati de 1,4-dihidro-4-oxonaftiridina |
RO126286A RO95509B (ro) | 1984-04-26 | 1985-04-24 | Procedeu pentru prepararea unor derivati de 1,4-dihidro-4-oxonaftiridina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO126286A RO95509B (ro) | 1984-04-26 | 1985-04-24 | Procedeu pentru prepararea unor derivati de 1,4-dihidro-4-oxonaftiridina |
Country Status (30)
Country | Link |
---|---|
JP (1) | JPS60228479A (no) |
KR (1) | KR870001693B1 (no) |
AR (1) | AR241911A1 (no) |
AT (2) | AT389698B (no) |
AU (2) | AU565087B2 (no) |
BE (1) | BE902279A (no) |
CH (1) | CH673458A5 (no) |
CS (1) | CS250684B2 (no) |
DD (1) | DD238795A5 (no) |
DE (2) | DE3514076A1 (no) |
DK (1) | DK165877C (no) |
EG (1) | EG17339A (no) |
ES (2) | ES8700256A1 (no) |
FI (1) | FI80453C (no) |
FR (2) | FR2563521B1 (no) |
GB (2) | GB2158825B (no) |
HU (2) | HU194226B (no) |
ID (1) | ID21142A (no) |
IL (1) | IL75021A (no) |
IT (1) | IT1209953B (no) |
LU (1) | LU85871A1 (no) |
NL (2) | NL187314C (no) |
NO (1) | NO162238C (no) |
NZ (1) | NZ211895A (no) |
PH (3) | PH22801A (no) |
PL (1) | PL147392B1 (no) |
PT (1) | PT80349B (no) |
RO (2) | RO91871B (no) |
SE (2) | SE463102B (no) |
ZA (1) | ZA853102B (no) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6172753A (ja) * | 1984-09-18 | 1986-04-14 | Dainippon Pharmaceut Co Ltd | ピリジルケトン誘導体 |
AT392789B (de) * | 1985-01-23 | 1991-06-10 | Toyama Chemical Co Ltd | Verfahren zur herstellung von 1-substituierten aryl-1,4-dihydro-4-oxonaphthyridinderivaten |
AU576657B2 (en) * | 1985-01-23 | 1988-09-01 | Toyama Chemical Co. Ltd. | Naphthyridine and pyridine derivatives |
DE3525108A1 (de) * | 1985-06-07 | 1986-12-11 | Bayer Ag, 5090 Leverkusen | Antibakteriell wirksame chinoloncarbonsaeureester |
DE3685157D1 (de) * | 1985-06-26 | 1992-06-11 | Daiichi Seiyaku Co | Pyridoncarbonsaeurederivate. |
US4962112A (en) * | 1987-08-04 | 1990-10-09 | Abbott Laboratories | 7-(2-methyl-4-aminopyrrolidinyl)naphthryidine and quinoline compounds |
IE62600B1 (en) * | 1987-08-04 | 1995-02-22 | Abbott Lab | Naphtyridine antianaerobic compounds |
US4859776A (en) * | 1988-03-11 | 1989-08-22 | Abbott Laboratories | (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation |
JP2844079B2 (ja) * | 1988-05-23 | 1999-01-06 | 塩野義製薬株式会社 | ピリドンカルボン酸系抗菌剤 |
DE3934082A1 (de) * | 1989-10-12 | 1991-04-18 | Bayer Ag | Chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung als antivirale mittel |
WO1992012155A1 (en) * | 1991-01-14 | 1992-07-23 | Hanmi Pharmaceutical Co., Ltd. | Novel quinolone compounds and processes for preparation thereof |
FR2692577B1 (fr) * | 1992-05-26 | 1996-02-02 | Bouchara Sa | Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant. |
KR940014395A (ko) * | 1992-12-09 | 1994-07-18 | 강박광 | 신규한 퀴놀론 유도체 및 그의 제조방법 |
KR0148277B1 (ko) * | 1993-01-18 | 1998-11-02 | 채영복 | 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법 |
AU4272793A (en) * | 1993-04-24 | 1994-11-21 | Korea Research Institute Of Chemical Technology | Novel quinolone carboxylic acid derivatives and process for preparing the same |
KR950018003A (ko) * | 1993-12-09 | 1995-07-22 | 스미스클라인 비참 피엘씨 | 신규한 퀴놀론 유도체 및 그의 제조 방법 |
EP0787720B1 (en) * | 1994-10-20 | 2003-07-16 | Wakunaga Seiyaku Kabushiki Kaisha | Pyridonecarboxylate derivative or salt thereof and antibacterial containing the same as active ingredient |
DK0897919T3 (da) | 1996-04-19 | 2004-09-27 | Wakunaga Pharma Co Ltd | Nye pyridoncarboxylsyrederivater eller salte deraf samt antibakterielle midler indeholdende disse som den aktive bestanddel |
WO1998018795A1 (de) * | 1996-10-30 | 1998-05-07 | Bayer Aktiengesellschaft | Verfahren zur herstellung von naphthyridinverbindungen und neue zwischenprodukte |
DE19713506A1 (de) | 1997-04-01 | 1998-10-08 | Bayer Ag | Verfahren zur Herstellung von 2,6-Dichlor-5-fluornicotinonitril und die chemische Verbindung 3-Cyano-2-hydroxy-5-fluorpyrid-6-on-mononatriumsalz sowie dessen Tautomere |
CN1343128B (zh) | 1999-03-17 | 2010-04-21 | 第一制药株式会社 | 药物组合物 |
DE19926400A1 (de) | 1999-06-10 | 2000-12-14 | Bayer Ag | Verbessertes Verfahren zur Herstellung von 2,6-Dichlor-5-fluor-nicotinsäure und grobteilige und besonders reine 2,6-Dichlor-5-fluor-nicotinsäure |
EP1219618A4 (en) | 1999-09-02 | 2002-09-18 | Wakunaga Pharma Co Ltd | QUINOLINECARBOXYLIC ACID DERIVATIVE OR ITS SALT |
AU2001286852A1 (en) * | 2000-08-29 | 2002-03-13 | Chiron Corporation | Quinoline antibacterial compounds and methods of use thereof |
KR100981351B1 (ko) * | 2003-10-29 | 2010-09-10 | 주식회사 엘지생명과학 | 7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법 |
CN101792443A (zh) * | 2010-03-09 | 2010-08-04 | 北京欧凯纳斯科技有限公司 | 氟代喹诺酮衍生物及其制备方法和用途 |
JOP20190045A1 (ar) | 2016-09-14 | 2019-03-14 | Bayer Ag | مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. |
CN114369092A (zh) * | 2021-12-20 | 2022-04-19 | 赤峰万泽药业股份有限公司 | 甲苯磺酸妥舒沙星及其制备方法 |
CN116606279A (zh) * | 2023-03-13 | 2023-08-18 | 广东工业大学 | 一种氟喹诺酮类化合物及其制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2125310A1 (en) * | 1971-05-21 | 1972-11-30 | Sterling Drug Inc , New York, NY (V St A) | 1-alkyl-1,4-dihydro-4-oxo-1,8-naphtyridine 3-carboxylic acids antibac |
AR223983A1 (es) * | 1978-08-25 | 1981-10-15 | Dainippon Pharmaceutical Co | Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico |
DE3033157A1 (de) * | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
US4382937A (en) * | 1981-02-27 | 1983-05-10 | Dainippon Pharmaceutical Co., Ltd. | Naphthyridine derivatives and their use as anti-bacterials |
IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
IL74064A (en) * | 1984-01-26 | 1988-09-30 | Abbott Lab | 1,7-disubstituted-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives and antibacterial compositions containing them |
NZ210847A (en) * | 1984-01-26 | 1988-02-29 | Abbott Lab | Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions |
AU576657B2 (en) * | 1985-01-23 | 1988-09-01 | Toyama Chemical Co. Ltd. | Naphthyridine and pyridine derivatives |
DE3525108A1 (de) * | 1985-06-07 | 1986-12-11 | Bayer Ag, 5090 Leverkusen | Antibakteriell wirksame chinoloncarbonsaeureester |
-
1984
- 1984-04-26 JP JP59084963A patent/JPS60228479A/ja active Granted
-
1985
- 1985-04-18 DE DE19853514076 patent/DE3514076A1/de active Granted
- 1985-04-18 DE DE3546658A patent/DE3546658C2/de not_active Expired - Lifetime
- 1985-04-23 GB GB08510297A patent/GB2158825B/en not_active Expired
- 1985-04-23 PH PH32174A patent/PH22801A/en unknown
- 1985-04-23 NL NLAANVRAGE8501172,A patent/NL187314C/xx not_active IP Right Cessation
- 1985-04-24 IL IL7502185A patent/IL75021A/en not_active IP Right Cessation
- 1985-04-24 RO RO118517A patent/RO91871B/ro unknown
- 1985-04-24 AU AU41650/85A patent/AU565087B2/en not_active Expired
- 1985-04-24 PT PT80349A patent/PT80349B/pt unknown
- 1985-04-24 DD DD85275518A patent/DD238795A5/de unknown
- 1985-04-24 RO RO126286A patent/RO95509B/ro unknown
- 1985-04-24 AT AT0122485A patent/AT389698B/de not_active IP Right Cessation
- 1985-04-24 NO NO851643A patent/NO162238C/no not_active IP Right Cessation
- 1985-04-24 NZ NZ211895A patent/NZ211895A/xx unknown
- 1985-04-24 EG EG261/85A patent/EG17339A/xx active
- 1985-04-25 KR KR1019850002822A patent/KR870001693B1/ko not_active IP Right Cessation
- 1985-04-25 DK DK185685A patent/DK165877C/da not_active IP Right Cessation
- 1985-04-25 HU HU851599A patent/HU194226B/hu unknown
- 1985-04-25 BE BE0/214909A patent/BE902279A/fr not_active IP Right Cessation
- 1985-04-25 CH CH1798/85A patent/CH673458A5/de not_active IP Right Cessation
- 1985-04-25 ID IDP980525A patent/ID21142A/id unknown
- 1985-04-25 HU HU873675A patent/HU197571B/hu unknown
- 1985-04-25 FI FI851637A patent/FI80453C/fi not_active IP Right Cessation
- 1985-04-25 AR AR85300190A patent/AR241911A1/es active
- 1985-04-25 ZA ZA853102A patent/ZA853102B/xx unknown
- 1985-04-25 ES ES542584A patent/ES8700256A1/es not_active Expired
- 1985-04-25 CS CS853035A patent/CS250684B2/cs not_active IP Right Cessation
- 1985-04-25 FR FR858506327A patent/FR2563521B1/fr not_active Expired
- 1985-04-25 SE SE8502017A patent/SE463102B/sv not_active IP Right Cessation
- 1985-04-26 LU LU85871A patent/LU85871A1/en unknown
- 1985-04-26 PL PL1985253108A patent/PL147392B1/pl unknown
- 1985-04-26 IT IT8548002A patent/IT1209953B/it active
-
1986
- 1986-01-31 ES ES551538A patent/ES8706673A1/es not_active Expired
-
1987
- 1987-07-17 GB GB8716897A patent/GB2191776B/en not_active Expired - Lifetime
- 1987-10-20 PH PH35960A patent/PH25228A/en unknown
- 1987-10-20 PH PH35958A patent/PH25046A/en unknown
- 1987-11-25 AU AU81804/87A patent/AU612993B2/en not_active Expired
-
1988
- 1988-06-30 FR FR888808836A patent/FR2614620B1/fr not_active Expired - Lifetime
- 1988-10-31 AT AT0267888A patent/AT390258B/de not_active IP Right Cessation
- 1988-12-20 SE SE8804586A patent/SE501412C2/sv not_active IP Right Cessation
-
1991
- 1991-04-15 NL NL9100648A patent/NL9100648A/nl not_active Application Discontinuation
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