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PT86526A - Processo para a preparacao de mono-hidrato de cefadroxil cristalino e de composicoes farmaceuticas que o contem - Google Patents

Processo para a preparacao de mono-hidrato de cefadroxil cristalino e de composicoes farmaceuticas que o contem

Info

Publication number
PT86526A
PT86526A PT86526A PT8652688A PT86526A PT 86526 A PT86526 A PT 86526A PT 86526 A PT86526 A PT 86526A PT 8652688 A PT8652688 A PT 8652688A PT 86526 A PT86526 A PT 86526A
Authority
PT
Portugal
Prior art keywords
cefadroxil
preparation
pharmaceutical compositions
compositions containing
monohydrate
Prior art date
Application number
PT86526A
Other languages
English (en)
Other versions
PT86526B (pt
Inventor
Leonardo Marsili
Original Assignee
Rifar Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rifar Srl filed Critical Rifar Srl
Publication of PT86526A publication Critical patent/PT86526A/pt
Publication of PT86526B publication Critical patent/PT86526B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT86526A 1987-08-03 1988-01-11 Processo para a preparacao de mono-hidrato de cefadroxil cristalino e de composicoes farmaceuticas que o contem PT86526B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/080,999 US4898938A (en) 1987-08-03 1987-08-03 Method for preparing crystalline cefadroxil monohydrate

Publications (2)

Publication Number Publication Date
PT86526A true PT86526A (pt) 1989-09-14
PT86526B PT86526B (pt) 1994-10-31

Family

ID=22161022

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86526A PT86526B (pt) 1987-08-03 1988-01-11 Processo para a preparacao de mono-hidrato de cefadroxil cristalino e de composicoes farmaceuticas que o contem

Country Status (18)

Country Link
US (1) US4898938A (pt)
EP (1) EP0302145B1 (pt)
JP (1) JP2655664B2 (pt)
KR (1) KR960002910B1 (pt)
CN (1) CN1016607B (pt)
AT (1) ATE105560T1 (pt)
AU (1) AU597136B2 (pt)
CA (1) CA1285554C (pt)
DE (1) DE3789810T2 (pt)
DK (1) DK680387A (pt)
ES (1) ES2056059T3 (pt)
FI (1) FI88043C (pt)
NO (1) NO168425C (pt)
PH (1) PH23648A (pt)
PT (1) PT86526B (pt)
RU (1) RU1804461C (pt)
YU (1) YU44649B (pt)
ZA (1) ZA879701B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0433428T3 (da) * 1989-07-10 1994-12-05 Chemferm Vof Hidtil ukendt stabil form af cephradin, fremgangsmåde til fremstilling deraf og mellemprodukter anvendt derved
IT1251999B (it) * 1991-11-11 1995-05-27 Opos Biochimica Srl Forma cristallina di un antibiotico cefalosporinico
US5589593A (en) * 1991-11-11 1996-12-31 Biochimica Opos Spa Crystalline form of a cephalosporin antibiotic
WO2003092626A2 (en) * 2002-05-03 2003-11-13 Smithkline Beecham Pharmco Puerto Rico, Inc. Carvedilol pharmasolve solvate
US20040077849A1 (en) * 2002-10-16 2004-04-22 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefadroxil
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
CN1311830C (zh) * 2004-02-27 2007-04-25 石药集团中奇制药技术（石家庄）有限公司 头孢羟氨苄口腔崩解片及其制备方法
JP2009537589A (ja) * 2006-05-19 2009-10-29 ディーエスエム アイピー アセッツ ビー．ブイ． セファドロキシルの結晶化法
CN102134250B (zh) * 2011-01-19 2013-03-13 天津大学 一种头孢羟氨苄单水合物的结晶方法及结晶
CN104447795B (zh) * 2014-11-28 2016-08-17 珠海金鸿药业股份有限公司 一种头孢羟氨苄化合物及其药物组合物
CN105534937B (zh) * 2015-12-30 2019-12-03 石药集团欧意药业有限公司 一种头孢羟氨苄片剂及其制备方法
CN106588953B (zh) * 2016-11-08 2018-11-27 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物头孢羟氨苄晶型化合物及其组合物
CN106588954B (zh) * 2016-11-08 2018-11-27 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物羟氨苄晶体化合物及其组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
GB8714180D0 (en) * 1987-06-17 1987-07-22 Rifar Srl Anhydrous crystalline cefadroxil
WO1988008320A1 (en) * 1987-04-24 1988-11-03 Invenmark Limited Puzzle

Also Published As

Publication number Publication date
EP0302145A2 (en) 1989-02-08
YU242787A (en) 1989-02-28
JPS6442487A (en) 1989-02-14
DE3789810T2 (de) 1994-08-18
ZA879701B (en) 1988-06-23
KR960002910B1 (ko) 1996-02-28
DK680387A (da) 1989-02-04
FI88043B (fi) 1992-12-15
ES2056059T3 (es) 1994-10-01
PT86526B (pt) 1994-10-31
FI881040A (fi) 1989-02-04
YU44649B (en) 1990-10-31
NO168425B (no) 1991-11-11
RU1804461C (ru) 1993-03-23
CN1031085A (zh) 1989-02-15
FI88043C (fi) 1993-03-25
FI881040A0 (fi) 1988-03-07
ATE105560T1 (de) 1994-05-15
DE3789810D1 (de) 1994-06-16
CN1016607B (zh) 1992-05-13
PH23648A (en) 1989-09-27
NO168425C (no) 1992-02-19
AU597136B2 (en) 1990-05-24
NO880026L (no) 1989-02-06
CA1285554C (en) 1991-07-02
US4898938A (en) 1990-02-06
DK680387D0 (da) 1987-12-22
EP0302145A3 (en) 1989-08-23
JP2655664B2 (ja) 1997-09-24
NO880026D0 (no) 1988-01-05
KR890003775A (ko) 1989-04-18
EP0302145B1 (en) 1994-05-11
AU8304587A (en) 1989-02-09

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940411

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19951031