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PT81229B - Processo para a preparacao de 1,3-dimetil-1h-purino-2,6-dionas contendo 1h-indol-3-ilo e de composicoes farmaceuticas contendo estes compostos - Google Patents

Processo para a preparacao de 1,3-dimetil-1h-purino-2,6-dionas contendo 1h-indol-3-ilo e de composicoes farmaceuticas contendo estes compostos

Info

Publication number
PT81229B
PT81229B PT81229A PT8122985A PT81229B PT 81229 B PT81229 B PT 81229B PT 81229 A PT81229 A PT 81229A PT 8122985 A PT8122985 A PT 8122985A PT 81229 B PT81229 B PT 81229B
Authority
PT
Portugal
Prior art keywords
compounds
indol
purine
dimethyl
dionas
Prior art date
Application number
PT81229A
Other languages
English (en)
Other versions
PT81229A (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT81229A publication Critical patent/PT81229A/pt
Publication of PT81229B publication Critical patent/PT81229B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
PT81229A 1984-10-01 1985-10-01 Processo para a preparacao de 1,3-dimetil-1h-purino-2,6-dionas contendo 1h-indol-3-ilo e de composicoes farmaceuticas contendo estes compostos PT81229B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/656,561 US4548939A (en) 1984-10-01 1984-10-01 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones

Publications (2)

Publication Number Publication Date
PT81229A PT81229A (en) 1985-11-01
PT81229B true PT81229B (pt) 1987-11-30

Family

ID=24633577

Family Applications (1)

Application Number Title Priority Date Filing Date
PT81229A PT81229B (pt) 1984-10-01 1985-10-01 Processo para a preparacao de 1,3-dimetil-1h-purino-2,6-dionas contendo 1h-indol-3-ilo e de composicoes farmaceuticas contendo estes compostos

Country Status (17)

Country Link
US (1) US4548939A (pt)
EP (1) EP0177087B1 (pt)
JP (1) JPH0653742B2 (pt)
CN (1) CN1011311B (pt)
AT (1) ATE60604T1 (pt)
AU (1) AU576386B2 (pt)
CA (1) CA1262348A (pt)
DE (1) DE3581577D1 (pt)
DK (1) DK163996C (pt)
ES (1) ES8609324A1 (pt)
FI (1) FI83220C (pt)
GR (1) GR852375B (pt)
IE (1) IE58747B1 (pt)
NO (1) NO162069C (pt)
NZ (1) NZ213498A (pt)
PT (1) PT81229B (pt)
ZA (1) ZA857553B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
AU611469B2 (en) * 1987-08-13 1991-06-13 Glaxo Group Limited Indole derivatives
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
DE8817122U1 (de) * 1988-12-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Xanthinderivate mit Adenosinantogenistischer Wirkung
DK292A (da) * 1991-11-29 1992-01-02 Tanisake Kk Middel
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
CN108042542A (zh) * 2007-06-22 2018-05-18 海德拉生物科学公司 用于治疗病症的方法和组合物
US8318728B2 (en) 2008-05-14 2012-11-27 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
DE2922159A1 (de) * 1979-05-31 1980-12-04 Boehringer Mannheim Gmbh Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
US4426383A (en) * 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.

Also Published As

Publication number Publication date
EP0177087A2 (en) 1986-04-09
ES8609324A1 (es) 1986-07-16
NZ213498A (en) 1988-04-29
DK163996B (da) 1992-04-27
IE58747B1 (en) 1993-11-03
FI853763L (fi) 1986-04-02
JPH0653742B2 (ja) 1994-07-20
NO162069C (no) 1989-11-01
JPS6187681A (ja) 1986-05-06
AU576386B2 (en) 1988-08-25
EP0177087A3 (en) 1986-06-11
DK444085A (da) 1986-04-02
ATE60604T1 (de) 1991-02-15
ZA857553B (en) 1987-05-27
US4548939A (en) 1985-10-22
DK163996C (da) 1992-09-21
PT81229A (en) 1985-11-01
AU4812485A (en) 1986-04-10
DK444085D0 (da) 1985-09-30
CA1262348A (en) 1989-10-17
NO162069B (no) 1989-07-24
ES547447A0 (es) 1986-07-16
EP0177087B1 (en) 1991-01-30
CN1011311B (zh) 1991-01-23
CN85105804A (zh) 1986-10-22
FI83220C (fi) 1991-06-10
FI853763A0 (fi) 1985-09-30
NO853856L (no) 1986-04-02
IE852403L (en) 1986-04-01
GR852375B (pt) 1986-01-31
DE3581577D1 (de) 1991-03-07
FI83220B (fi) 1991-02-28

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Effective date: 19941130