NO162069C - Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner. - Google Patents

Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner.

Info

Publication number: NO162069C
Authority: NO; Norway
Prior art keywords: indol; preparing; purin; dione; methyl
Prior art date: 1984-10-01

Application number

NO853856A

Other languages

English (en)

Norwegian (no)

Other versions

NO162069B (no

NO853856L (no

Inventor

Ludo Edmond Josephine Kennis

Jan Vandenberk

Jozef Martin Boey

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-01

Filing date

1985-09-30

Publication date

1989-11-01

1985-09-30 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1986-04-02 Publication of NO853856L publication Critical patent/NO853856L/no

1989-07-24 Publication of NO162069B publication Critical patent/NO162069B/no

1989-11-01 Publication of NO162069C publication Critical patent/NO162069C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)

NO853856A 1984-10-01 1985-09-30 Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner. NO162069C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/656,561 US4548939A (en)	1984-10-01	1984-10-01	1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones

Publications (3)

Publication Number	Publication Date
NO853856L NO853856L (no)	1986-04-02
NO162069B NO162069B (no)	1989-07-24
NO162069C true NO162069C (no)	1989-11-01

Family

ID=24633577

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO853856A NO162069C (no)	1984-10-01	1985-09-30	Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner.

Country Status (17)

Country	Link
US (1)	US4548939A (pt)
EP (1)	EP0177087B1 (pt)
JP (1)	JPH0653742B2 (pt)
CN (1)	CN1011311B (pt)
AT (1)	ATE60604T1 (pt)
AU (1)	AU576386B2 (pt)
CA (1)	CA1262348A (pt)
DE (1)	DE3581577D1 (pt)
DK (1)	DK163996C (pt)
ES (1)	ES8609324A1 (pt)
FI (1)	FI83220C (pt)
GR (1)	GR852375B (pt)
IE (1)	IE58747B1 (pt)
NO (1)	NO162069C (pt)
NZ (1)	NZ213498A (pt)
PT (1)	PT81229B (pt)
ZA (1)	ZA857553B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH648559A5 (de) *	1981-07-20	1985-03-29	Siegfried Ag	Theophyllinderivate und verfahren zu deren herstellung.
US4742057A (en) *	1985-12-05	1988-05-03	Fujisawa Pharmaceutical Co., Ltd.	Antiallergic thiazole compounds
AU611469B2 (en) *	1987-08-13	1991-06-13	Glaxo Group Limited	Indole derivatives
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
DK733788A (da) *	1988-01-14	1989-07-15	Fujisawa Pharmaceutical Co	Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
DE8817122U1 (de) *	1988-12-22	1993-02-04	Boehringer Ingelheim Kg, 55218 Ingelheim	Neue Xanthinderivate mit Adenosinantogenistischer Wirkung
DK292A (da) *	1991-11-29	1992-01-02	Tanisake Kk	Middel
DE4414113A1 (de) *	1994-04-22	1995-10-26	Merck Patent Gmbh	3-Indolylpiperidine
CN108042542A (zh) *	2007-06-22	2018-05-18	海德拉生物科学公司	用于治疗病症的方法和组合物
US8318728B2 (en)	2008-05-14	2012-11-27	Hydra Biosciences, Inc.	Compounds and compositions for treating chemical warfare agent-induced injuries
WO2009140517A1 (en)	2008-05-14	2009-11-19	Hydra Biosciences, Inc.	Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2322470A1 (de) *	1973-05-04	1974-11-21	Boehringer Sohn Ingelheim	Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2334358A1 (fr) *	1975-12-12	1977-07-08	Sogeras	Nouveaux medicaments derives de l'indole
FR2362628A1 (fr) *	1976-08-26	1978-03-24	Roussel Uclaf	Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
EP0011399A1 (en) *	1978-11-11	1980-05-28	FISONS plc	N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
DE2922159A1 (de) *	1979-05-31	1980-12-04	Boehringer Mannheim Gmbh	Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4342870A (en) *	1980-03-28	1982-08-03	Janssen Pharmaceutica N.V.	Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
US4426383A (en) *	1980-09-04	1984-01-17	Eisai Co., Ltd.	Theophylline and theobromine derivatives
US4359468A (en) *	1981-02-25	1982-11-16	Boehringer Ingelheim Ltd.	Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
US4443451A (en) *	1981-07-15	1984-04-17	Janssen Pharmaceutica N.V.	Bicyclic pyrimidin-5-one derivatives
CH648559A5 (de) *	1981-07-20	1985-03-29	Siegfried Ag	Theophyllinderivate und verfahren zu deren herstellung.

1984
- 1984-10-01 US US06/656,561 patent/US4548939A/en not_active Expired - Fee Related
1985
- 1985-07-30 CN CN85105804A patent/CN1011311B/zh not_active Expired
- 1985-09-10 CA CA000490317A patent/CA1262348A/en not_active Expired
- 1985-09-16 NZ NZ213498A patent/NZ213498A/en unknown
- 1985-09-18 AT AT85201484T patent/ATE60604T1/de not_active IP Right Cessation
- 1985-09-18 DE DE8585201484T patent/DE3581577D1/de not_active Expired - Fee Related
- 1985-09-18 EP EP85201484A patent/EP0177087B1/en not_active Expired - Lifetime
- 1985-09-27 JP JP60212731A patent/JPH0653742B2/ja not_active Expired - Lifetime
- 1985-09-30 AU AU48124/85A patent/AU576386B2/en not_active Ceased
- 1985-09-30 IE IE240385A patent/IE58747B1/en not_active IP Right Cessation
- 1985-09-30 FI FI853763A patent/FI83220C/fi not_active IP Right Cessation
- 1985-09-30 GR GR852375A patent/GR852375B/el unknown
- 1985-09-30 NO NO853856A patent/NO162069C/no unknown
- 1985-09-30 ZA ZA857553A patent/ZA857553B/xx unknown
- 1985-09-30 ES ES547447A patent/ES8609324A1/es not_active Expired
- 1985-09-30 DK DK444085A patent/DK163996C/da not_active IP Right Cessation
- 1985-10-01 PT PT81229A patent/PT81229B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0177087A2 (en)	1986-04-09
ES8609324A1 (es)	1986-07-16
NZ213498A (en)	1988-04-29
DK163996B (da)	1992-04-27
IE58747B1 (en)	1993-11-03
FI853763L (fi)	1986-04-02
JPH0653742B2 (ja)	1994-07-20
JPS6187681A (ja)	1986-05-06
AU576386B2 (en)	1988-08-25
EP0177087A3 (en)	1986-06-11
DK444085A (da)	1986-04-02
ATE60604T1 (de)	1991-02-15
ZA857553B (en)	1987-05-27
US4548939A (en)	1985-10-22
DK163996C (da)	1992-09-21
PT81229A (en)	1985-11-01
PT81229B (pt)	1987-11-30
AU4812485A (en)	1986-04-10
DK444085D0 (da)	1985-09-30
CA1262348A (en)	1989-10-17
NO162069B (no)	1989-07-24
ES547447A0 (es)	1986-07-16
EP0177087B1 (en)	1991-01-30
CN1011311B (zh)	1991-01-23
CN85105804A (zh)	1986-10-22
FI83220C (fi)	1991-06-10
FI853763A0 (fi)	1985-09-30
NO853856L (no)	1986-04-02
IE852403L (en)	1986-04-01
GR852375B (pt)	1986-01-31
DE3581577D1 (de)	1991-03-07
FI83220B (fi)	1991-02-28

Publication	Publication Date	Title
ES8706668A1 (es)	1987-06-16	Un procedimiento para la preparacion de derivados de piperidina.
ES8603870A1 (es)	1986-01-01	Un procedimiento para la preparacion de derivados de 2,2'-iminobisetanol.
PH21554A (en)	1987-12-11	N-(4-piperidinyl)bicyclic condensed-2-imidazolamine derivatives
HUT42095A (en)	1987-06-29	Process for producing purine ring or analogue ring-systhems /heteropurine/-containing compounds and pharmaceutical compositions containing them
ES8602763A1 (es)	1985-11-16	Un procedimiento para la preparacion de n-(heterociclilbiciclo)-4-piperidinaminas.
TNSN90003A1 (fr)	1991-03-05	Derives de 2-aminopyrimidinones utiles notamment comme antagonistes des neurotransmetteurs et procede pour leur preparation
PH25504A (en)	1991-07-24	Novel substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides pharmaceutical composition containing said compound, method of use thereof
NO162069C (no)	1989-11-01	Analogifremgangsmaate for fremstilling av 1h-indol-3-yl inneholdende 1,3-di-metyl-1h-purin-2,6-dioner.
EP0184258A3 (en)	1987-05-13	Novel derivatives of hydroxy- or amino-substituted (piperidinylalkyl)quinazolines
HUT53664A (en)	1990-11-28	Process for producing enzyme inhibiting amino acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient
ZM7585A1 (en)	1986-04-28	Amide derivatives
HUT51622A (en)	1990-05-28	Process for producing 3-piperidinole-indazole derivatives and pharmaceutical preparations having effect against high blood pressure containing these compounds as active substance