PT81872B - Processo para a preparacao de glucagon ou dos seus derivados em uma estirpe de levedura transformada - Google Patents

Processo para a preparacao de glucagon ou dos seus derivados em uma estirpe de levedura transformada

Info

Publication number: PT81872B
Authority: PT; Portugal
Prior art keywords: derivatives; glucagon; string; transformed yeast; yeast
Prior art date: 1985-01-22

Application number

PT81872A

Other languages

English (en)

Other versions

PT81872A (en

Inventor

Kjeld Norris

Lars Thim

Mogens Trier Hansen

Fanny Norris

Alister James Moody

Original Assignee

Novo Industri As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-22

Filing date

1986-01-20

Publication date

1988-05-27

1986-01-20 Application filed by Novo Industri As filed Critical Novo Industri As

1986-02-01 Publication of PT81872A publication Critical patent/PT81872A/pt

1988-05-27 Publication of PT81872B publication Critical patent/PT81872B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/30—Signal or leader sequence

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Mycology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Diabetes (AREA)
Plant Pathology (AREA)
Emergency Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PT81872A 1985-01-22 1986-01-20 Processo para a preparacao de glucagon ou dos seus derivados em uma estirpe de levedura transformada PT81872B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK27885A DK27885A (da)	1985-01-22	1985-01-22	Fremstilling af peptider

Publications (2)

Publication Number	Publication Date
PT81872A PT81872A (en)	1986-02-01
PT81872B true PT81872B (pt)	1988-05-27

Family

ID=8091749

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT81872A PT81872B (pt)	1985-01-22	1986-01-20	Processo para a preparacao de glucagon ou dos seus derivados em uma estirpe de levedura transformada

Country Status (17)

Country	Link
US (1)	US4826763A (pt)
EP (1)	EP0189998B1 (pt)
JP (2)	JPH0720435B2 (pt)
AT (1)	ATE48643T1 (pt)
AU (1)	AU587218B2 (pt)
CA (1)	CA1294232C (pt)
DE (1)	DE3667488D1 (pt)
DK (1)	DK27885A (pt)
ES (1)	ES8708250A1 (pt)
FI (1)	FI87800C (pt)
GR (1)	GR860149B (pt)
IE (1)	IE58726B1 (pt)
MX (1)	MX163776B (pt)
NO (1)	NO172185C (pt)
NZ (1)	NZ214883A (pt)
PT (1)	PT81872B (pt)
ZA (1)	ZA86393B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5151354A (en) *	1986-08-21	1992-09-29	Cornelius Hollenberg	Fermentation processes using amylolytic enzyme producing microorganisms
EP0268772B1 (en) *	1986-09-19	1995-04-26	ZymoGenetics, Inc.	Expression of biologically active factor XIII
JPH01187499A (ja) *	1988-01-21	1989-07-26	Science & Tech Agency	原子炉解体用ロボット
ZA90533B (en) *	1989-02-01	1990-10-31	Shionogi & Co	A method for the production of glucagon
US6172039B1 (en)	1990-04-16	2001-01-09	Apex Bioscience, Inc.	Expression of recombinant hemoglobin and hemoglobin variants in yeast
US5234906A (en) *	1991-01-10	1993-08-10	Amylin Pharmaceuticals, Inc.	Hyperglycemic compositions
US5510459A (en) *	1991-01-17	1996-04-23	Zymogenetics, Inc.	Glucagon antagonists
US5408037A (en) *	1991-01-17	1995-04-18	Zymogenetics, Inc.	Methods for detecting glucagon antagonists
WO1994001215A1 (en) *	1992-07-06	1994-01-20	Beckman Instruments, Inc.	Fluid delivery system utilizing multiple port valve
DK144093D0 (pt) *	1993-12-23	1993-12-23	Novo Nordisk As
US5652216A (en) *	1994-05-26	1997-07-29	Novo Nordisk A/S	Pharmaceutical preparation
DK0981362T3 (da) *	1997-05-16	2004-03-15	Ontario Inc 1149336	Anvendelse af GLP-2-agonister, der forbedrer funktionen af den øvre mavetarmkanal
CN1732012A (zh) *	2002-12-27	2006-02-08	迪奥贝克斯公司	用于预防和控制胰岛素诱发的低血糖的组合物和方法
US7655618B2 (en)	2002-12-27	2010-02-02	Diobex, Inc.	Compositions and methods for the prevention and control of insulin-induced hypoglycemia
MX2011008094A (es)	2009-02-03	2012-02-13	Amunix Operating Inc	Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos.
CN102481331B (zh)	2009-06-08	2017-09-22	阿穆尼克斯运营公司	葡萄糖调节多肽及其制备和使用方法
MX366864B (es)	2012-02-27	2019-07-26	Amunix Operating Inc	Composiciones de conjugados de xten y métodos para realizarlas.
EP3864032B1 (en)	2018-10-09	2022-11-30	Fresenius Kabi iPSUM S.r.l.	Process for the manufacture of glp-1 analogues
EP3753946A1 (en)	2019-06-18	2020-12-23	Fresenius Kabi iPSUM S.r.l.	Improved process for the preparation of high purity glucagon
WO2020254479A1 (en)	2019-06-18	2020-12-24	Fresenius Kabi Ipsum S.R.L.	Process for the manufacture of glucagon
BR112022009217A2 (pt)	2019-11-13	2022-08-02	Amunix Pharmaceuticals Inc	Polipeptídeos xten com código de barras e composições destes, e métodos para produzir e usar os mesmos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4401759A (en) *	1980-05-01	1983-08-30	Harvey Rubin	Detection and isolation of glucagon mRNA using a synthetic oligodeoxynucleotide
DK283180A (da) *	1980-07-01	1982-01-02	Novo Industri As	Polypeptider og derivater deraf
US4546082A (en) *	1982-06-17	1985-10-08	Regents Of The Univ. Of California	E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins

1985
- 1985-01-22 DK DK27885A patent/DK27885A/da unknown
1986
- 1986-01-20 DE DE8686300384T patent/DE3667488D1/de not_active Expired - Lifetime
- 1986-01-20 JP JP61009822A patent/JPH0720435B2/ja not_active Expired - Lifetime
- 1986-01-20 ZA ZA86393A patent/ZA86393B/xx unknown
- 1986-01-20 FI FI860251A patent/FI87800C/fi not_active IP Right Cessation
- 1986-01-20 NO NO860178A patent/NO172185C/no not_active IP Right Cessation
- 1986-01-20 PT PT81872A patent/PT81872B/pt active IP Right Revival
- 1986-01-20 MX MX1277A patent/MX163776B/es unknown
- 1986-01-20 GR GR860149A patent/GR860149B/el active IP Right Revival
- 1986-01-20 ES ES551042A patent/ES8708250A1/es not_active Expired
- 1986-01-20 EP EP86300384A patent/EP0189998B1/en not_active Expired
- 1986-01-20 AU AU52472/86A patent/AU587218B2/en not_active Expired
- 1986-01-20 CA CA000499911A patent/CA1294232C/en not_active Expired - Lifetime
- 1986-01-20 AT AT86300384T patent/ATE48643T1/de not_active IP Right Cessation
- 1986-01-20 IE IE16286A patent/IE58726B1/en not_active IP Right Cessation
- 1986-01-21 US US06/820,144 patent/US4826763A/en not_active Expired - Lifetime
- 1986-01-21 NZ NZ214883A patent/NZ214883A/en unknown
1993
- 1993-10-13 JP JP5255433A patent/JPH0746986B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
MX163776B (es)	1992-06-22
US4826763A (en)	1989-05-02
AU587218B2 (en)	1989-08-10
DK27885A (da)	1986-07-23
CA1294232C (en)	1992-01-14
JPH0746986B2 (ja)	1995-05-24
ES8708250A1 (es)	1987-10-01
NO172185C (no)	1993-06-16
JPH06292594A (ja)	1994-10-21
AU5247286A (en)	1986-07-31
DK27885D0 (da)	1985-01-22
IE58726B1 (en)	1993-11-03
FI87800B (fi)	1992-11-13
NZ214883A (en)	1988-04-29
DE3667488D1 (de)	1990-01-18
FI860251A (fi)	1986-07-23
EP0189998A1 (en)	1986-08-06
IE860162L (en)	1986-07-22
EP0189998B1 (en)	1989-12-13
ES551042A0 (es)	1987-10-01
FI87800C (fi)	1993-02-25
ATE48643T1 (de)	1989-12-15
NO172185B (no)	1993-03-08
NO860178L (no)	1986-07-23
JPH0720435B2 (ja)	1995-03-08
ZA86393B (en)	1987-03-25
JPS61181398A (ja)	1986-08-14
GR860149B (en)	1986-05-21
PT81872A (en)	1986-02-01
FI860251A0 (fi)	1986-01-20

Publication	Publication Date	Title
PT81872B (pt)	1988-05-27	Processo para a preparacao de glucagon ou dos seus derivados em uma estirpe de levedura transformada
AU573768B2 (en)	1988-06-23	Hyaluronic acid from streptococci
ES2169095T3 (es)	2002-07-01	Proteinas con actividad de factor viii, procedimiento para su produccion utilizando celulas modificadas por ingenieria genetica y composiciones farmaceuticas que los contienen.
PT87261A (pt)	1988-05-01	Processo de preparacao de heparinas de baixo peso molecular,com estrutura regular e de composicoes farmaceuticas que as contem
AU6231990A (en)	1990-12-06	Method of producing high molecular weight sodium hyaluronate by fermentation of streptococcus
AU6733487A (en)	1987-06-02	Mammalian interleukin-4
IL91413A0 (en)	1990-04-29	Process and solution for lyophilization of cells
FI864319A0 (fi)	1986-10-24	Menetelmä polypeptidien korkeatasoiseksi ilmentämiseksi Pichia-suvun hiivassa
AU4833897A (en)	1998-04-23	Glial mitogenic factors, their preparation and use
NO176921C (no)	1995-06-21	Genteknologisk fremgangsmåte for fremstilling av et tPA-lignende protein, samt vertscelle som er i stand til å uttrykke et slikt protein
BR8203507A (pt)	1983-06-07	Polipeptideo sequencia de dna veiculo de expressao microbiana replicavel plasmideo microorganismo cultura microbiana uso de um polipeptideo vacina e processo para producao de um polipeptideo
PT93164A (pt)	1990-08-31	Processo para a preparacao de tereftalato de dimetilo (dmt) com um determinado grau de pureza, usado como produto intermediario, assim como o seu processamentopara a obtencao de dmt muito puro e/ou de acido tereftalico de pureza media ou elevada
IE840258L (en)	1984-08-07	Expression of gene products.
EP0363127A3 (en)	1992-03-04	Improvements in or relating to eukaryotic expression
EP0276778A3 (en)	1990-01-10	High level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity
EP0196879A3 (en)	1988-03-16	Method of producing hairless pigs
EP0292808A3 (en)	1990-09-19	Substituted vinyl cephalosporins, process for their preparation and their use as medicines
Huff et al.	1978	Epidermal growth factor stimulates the phosphorylation of a specific nuclear protein in chick embryo epidermis
DK28386A (da)	1986-07-23	Fremstilling af peptider
AU2278392A (en)	1993-02-11	Method for producing recombinant proteins and host cells used therein
Hancock et al.	1979	Release of Complex Carbohydrates into Culture Medium by Cultured Hamster Cells

Legal Events

Date	Code	Title	Description
1994-07-29	PD3A	Change of proprietorship
1998-12-31	NF3A	Restitutio in integrum	Effective date: 19980925