NO172185C - Fremgangsmaate for fremstilling av glukagon - Google Patents

Fremgangsmaate for fremstilling av glukagon

Info

Publication number: NO172185C
Authority: NO; Norway
Prior art keywords: glucagon; derivatives; expression; yeast; fragments
Prior art date: 1985-01-22

Application number

NO860178A

Other languages

English (en)

Other versions

NO172185B (no

NO860178L (no

Inventor

Kjeld Norris

Lars Thim

Fanny Norris

Mogens Trier Hansen

Alister James Moody

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-22

Filing date

1986-01-20

Publication date

1993-06-16

1986-01-20 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1986-07-23 Publication of NO860178L publication Critical patent/NO860178L/no

1993-03-08 Publication of NO172185B publication Critical patent/NO172185B/no

1993-06-16 Publication of NO172185C publication Critical patent/NO172185C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/30—Signal or leader sequence

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Mycology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Diabetes (AREA)
Plant Pathology (AREA)
Emergency Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO860178A 1985-01-22 1986-01-20 Fremgangsmaate for fremstilling av glukagon NO172185C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK27885A DK27885A (da)	1985-01-22	1985-01-22	Fremstilling af peptider

Publications (3)

Publication Number	Publication Date
NO860178L NO860178L (no)	1986-07-23
NO172185B NO172185B (no)	1993-03-08
NO172185C true NO172185C (no)	1993-06-16

Family

ID=8091749

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO860178A NO172185C (no)	1985-01-22	1986-01-20	Fremgangsmaate for fremstilling av glukagon

Country Status (17)

Country	Link
US (1)	US4826763A (no)
EP (1)	EP0189998B1 (no)
JP (2)	JPH0720435B2 (no)
AT (1)	ATE48643T1 (no)
AU (1)	AU587218B2 (no)
CA (1)	CA1294232C (no)
DE (1)	DE3667488D1 (no)
DK (1)	DK27885A (no)
ES (1)	ES8708250A1 (no)
FI (1)	FI87800C (no)
GR (1)	GR860149B (no)
IE (1)	IE58726B1 (no)
MX (1)	MX163776B (no)
NO (1)	NO172185C (no)
NZ (1)	NZ214883A (no)
PT (1)	PT81872B (no)
ZA (1)	ZA86393B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5151354A (en) *	1986-08-21	1992-09-29	Cornelius Hollenberg	Fermentation processes using amylolytic enzyme producing microorganisms
EP0268772B1 (en) *	1986-09-19	1995-04-26	ZymoGenetics, Inc.	Expression of biologically active factor XIII
JPH01187499A (ja) *	1988-01-21	1989-07-26	Science & Tech Agency	原子炉解体用ロボット
ZA90533B (en) *	1989-02-01	1990-10-31	Shionogi & Co	A method for the production of glucagon
US6172039B1 (en)	1990-04-16	2001-01-09	Apex Bioscience, Inc.	Expression of recombinant hemoglobin and hemoglobin variants in yeast
US5234906A (en) *	1991-01-10	1993-08-10	Amylin Pharmaceuticals, Inc.	Hyperglycemic compositions
US5510459A (en) *	1991-01-17	1996-04-23	Zymogenetics, Inc.	Glucagon antagonists
US5408037A (en) *	1991-01-17	1995-04-18	Zymogenetics, Inc.	Methods for detecting glucagon antagonists
WO1994001215A1 (en) *	1992-07-06	1994-01-20	Beckman Instruments, Inc.	Fluid delivery system utilizing multiple port valve
DK144093D0 (no) *	1993-12-23	1993-12-23	Novo Nordisk As
US5652216A (en) *	1994-05-26	1997-07-29	Novo Nordisk A/S	Pharmaceutical preparation
DK0981362T3 (da) *	1997-05-16	2004-03-15	Ontario Inc 1149336	Anvendelse af GLP-2-agonister, der forbedrer funktionen af den øvre mavetarmkanal
CN1732012A (zh) *	2002-12-27	2006-02-08	迪奥贝克斯公司	用于预防和控制胰岛素诱发的低血糖的组合物和方法
US7655618B2 (en)	2002-12-27	2010-02-02	Diobex, Inc.	Compositions and methods for the prevention and control of insulin-induced hypoglycemia
MX2011008094A (es)	2009-02-03	2012-02-13	Amunix Operating Inc	Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos.
CN102481331B (zh)	2009-06-08	2017-09-22	阿穆尼克斯运营公司	葡萄糖调节多肽及其制备和使用方法
MX366864B (es)	2012-02-27	2019-07-26	Amunix Operating Inc	Composiciones de conjugados de xten y métodos para realizarlas.
EP3864032B1 (en)	2018-10-09	2022-11-30	Fresenius Kabi iPSUM S.r.l.	Process for the manufacture of glp-1 analogues
EP3753946A1 (en)	2019-06-18	2020-12-23	Fresenius Kabi iPSUM S.r.l.	Improved process for the preparation of high purity glucagon
WO2020254479A1 (en)	2019-06-18	2020-12-24	Fresenius Kabi Ipsum S.R.L.	Process for the manufacture of glucagon
BR112022009217A2 (pt)	2019-11-13	2022-08-02	Amunix Pharmaceuticals Inc	Polipeptídeos xten com código de barras e composições destes, e métodos para produzir e usar os mesmos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4401759A (en) *	1980-05-01	1983-08-30	Harvey Rubin	Detection and isolation of glucagon mRNA using a synthetic oligodeoxynucleotide
DK283180A (da) *	1980-07-01	1982-01-02	Novo Industri As	Polypeptider og derivater deraf
US4546082A (en) *	1982-06-17	1985-10-08	Regents Of The Univ. Of California	E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins

1985
- 1985-01-22 DK DK27885A patent/DK27885A/da unknown
1986
- 1986-01-20 DE DE8686300384T patent/DE3667488D1/de not_active Expired - Lifetime
- 1986-01-20 JP JP61009822A patent/JPH0720435B2/ja not_active Expired - Lifetime
- 1986-01-20 ZA ZA86393A patent/ZA86393B/xx unknown
- 1986-01-20 FI FI860251A patent/FI87800C/fi not_active IP Right Cessation
- 1986-01-20 NO NO860178A patent/NO172185C/no not_active IP Right Cessation
- 1986-01-20 PT PT81872A patent/PT81872B/pt active IP Right Revival
- 1986-01-20 MX MX1277A patent/MX163776B/es unknown
- 1986-01-20 GR GR860149A patent/GR860149B/el active IP Right Revival
- 1986-01-20 ES ES551042A patent/ES8708250A1/es not_active Expired
- 1986-01-20 EP EP86300384A patent/EP0189998B1/en not_active Expired
- 1986-01-20 AU AU52472/86A patent/AU587218B2/en not_active Expired
- 1986-01-20 CA CA000499911A patent/CA1294232C/en not_active Expired - Lifetime
- 1986-01-20 AT AT86300384T patent/ATE48643T1/de not_active IP Right Cessation
- 1986-01-20 IE IE16286A patent/IE58726B1/en not_active IP Right Cessation
- 1986-01-21 US US06/820,144 patent/US4826763A/en not_active Expired - Lifetime
- 1986-01-21 NZ NZ214883A patent/NZ214883A/en unknown
1993
- 1993-10-13 JP JP5255433A patent/JPH0746986B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
MX163776B (es)	1992-06-22
US4826763A (en)	1989-05-02
AU587218B2 (en)	1989-08-10
DK27885A (da)	1986-07-23
PT81872B (pt)	1988-05-27
CA1294232C (en)	1992-01-14
JPH0746986B2 (ja)	1995-05-24
ES8708250A1 (es)	1987-10-01
JPH06292594A (ja)	1994-10-21
AU5247286A (en)	1986-07-31
DK27885D0 (da)	1985-01-22
IE58726B1 (en)	1993-11-03
FI87800B (fi)	1992-11-13
NZ214883A (en)	1988-04-29
DE3667488D1 (de)	1990-01-18
FI860251A (fi)	1986-07-23
EP0189998A1 (en)	1986-08-06
IE860162L (en)	1986-07-22
EP0189998B1 (en)	1989-12-13
ES551042A0 (es)	1987-10-01
FI87800C (fi)	1993-02-25
ATE48643T1 (de)	1989-12-15
NO172185B (no)	1993-03-08
NO860178L (no)	1986-07-23
JPH0720435B2 (ja)	1995-03-08
ZA86393B (en)	1987-03-25
JPS61181398A (ja)	1986-08-14
GR860149B (en)	1986-05-21
PT81872A (en)	1986-02-01
FI860251A0 (fi)	1986-01-20

Publication	Publication Date	Title
NO172185C (no)	1993-06-16	Fremgangsmaate for fremstilling av glukagon
AU2790292A (en)	1993-04-27	Viral recombinant vectors for expression in muscle cells
BG47033A3 (en)	1990-04-16	Method for preparing of derivatives of imidazolamine
AU573768B2 (en)	1988-06-23	Hyaluronic acid from streptococci
HU9201712D0 (en)	1992-09-28	A mammalian cytokine, il-11
BG49717A3 (en)	1992-01-15	Method for preparing of chirudine
ES2169095T3 (es)	2002-07-01	Proteinas con actividad de factor viii, procedimiento para su produccion utilizando celulas modificadas por ingenieria genetica y composiciones farmaceuticas que los contienen.
AU4833897A (en)	1998-04-23	Glial mitogenic factors, their preparation and use
EP0853121A3 (en)	1998-08-05	Human DNase
NO871785D0 (no)	1987-04-29	Fremgangsmaate for fremstilling av et proteinprodukt, samt vektorsystem for fremgangsmaatens utfoerelse.
AU6733487A (en)	1987-06-02	Mammalian interleukin-4
NZ221119A (en)	1990-08-28	Proteins with factor viii activity produced by microorganisms produced by genetic engineering
AU682140B2 (en)	1997-09-18	Multidrug resistance gene
IE840258L (en)	1984-08-07	Expression of gene products.
IL75963A0 (en)	1985-12-31	Interferon derivatives,their preparation and pharmaceutical compositions containing them
DE3888459D1 (de)	1994-04-21	Zellzüchtung in kontinuierlicher Dispersionskultur mit einem System zur Gewinnung von Zellprodukten.
AU2179688A (en)	1989-03-02	Recombinant eukaryotic cells production interleukin-2, process and vectors for their preparation and process for the preparation of interleukin-2
EP0363127A3 (en)	1992-03-04	Improvements in or relating to eukaryotic expression
ATE175237T1 (de)	1999-01-15	Polypeptide beteiligt an der kobalamin- und/oder kobamid-biosynthese, für diese kodierende dns- sequencen, und ihre herstellung und vewendung.
EP0276778A3 (en)	1990-01-10	High level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity
AU2209988A (en)	1989-04-20	Method for increasing the expression of polypeptides in recombinant cell culture
IT8521507A0 (it)	1985-07-10	Vettore di clonaggio, molecole di dna ricombinante, ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni.
AU2278392A (en)	1993-02-11	Method for producing recombinant proteins and host cells used therein
DK28386A (da)	1986-07-23	Fremstilling af peptider
AU3434789A (en)	1989-10-16	The gene encoding phosphoribosylaminoimidazolecarboxylase of schwanniomyces occidentalis

Legal Events

Date	Code	Title	Description
2004-12-13	MM1K	Lapsed by not paying the annual fees