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PT690856E - Compostos anti-tumor composicoes farmaceuticas metodos de preparacao dos mesmos e de tratamento - Google Patents

Compostos anti-tumor composicoes farmaceuticas metodos de preparacao dos mesmos e de tratamento

Info

Publication number
PT690856E
PT690856E PT94912300T PT94912300T PT690856E PT 690856 E PT690856 E PT 690856E PT 94912300 T PT94912300 T PT 94912300T PT 94912300 T PT94912300 T PT 94912300T PT 690856 E PT690856 E PT 690856E
Authority
PT
Portugal
Prior art keywords
treatment
pharmaceutical compositions
preparation
same
tumor compounds
Prior art date
Application number
PT94912300T
Other languages
English (en)
Inventor
Iwao Ojima
Ezio Bompardelli
Original Assignee
Res Found Of State Univ Of New
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Found Of State Univ Of New, Indena Spa filed Critical Res Found Of State Univ Of New
Publication of PT690856E publication Critical patent/PT690856E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT94912300T 1993-03-26 1994-03-24 Compostos anti-tumor composicoes farmaceuticas metodos de preparacao dos mesmos e de tratamento PT690856E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/040,189 US5475011A (en) 1993-03-26 1993-03-26 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Publications (1)

Publication Number Publication Date
PT690856E true PT690856E (pt) 2003-04-30

Family

ID=21909617

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94912300T PT690856E (pt) 1993-03-26 1994-03-24 Compostos anti-tumor composicoes farmaceuticas metodos de preparacao dos mesmos e de tratamento

Country Status (19)

Country Link
US (3) US5475011A (pt)
EP (1) EP0690856B1 (pt)
JP (2) JP3157165B2 (pt)
KR (1) KR100223720B1 (pt)
CN (1) CN1067682C (pt)
AT (1) ATE229018T1 (pt)
AU (1) AU676041B2 (pt)
CA (1) CA2158147C (pt)
CZ (1) CZ288924B6 (pt)
DE (1) DE69431833T2 (pt)
DK (1) DK0690856T3 (pt)
ES (1) ES2190440T3 (pt)
HU (1) HUT73848A (pt)
NO (1) NO311722B1 (pt)
PL (2) PL179587B1 (pt)
PT (1) PT690856E (pt)
RU (1) RU2137764C1 (pt)
SK (1) SK282317B6 (pt)
WO (1) WO1994022856A1 (pt)

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US5807888A (en) * 1995-12-13 1998-09-15 Xechem International, Inc. Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US5854278A (en) * 1995-12-13 1998-12-29 Xechem International, Inc. Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US6177456B1 (en) 1995-10-02 2001-01-23 Xechem International, Inc. Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
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ITMI991483A1 (it) 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
DE60032633T2 (de) * 1999-11-24 2007-10-04 Immunogen Inc., Cambridge Zytotoxische mittel, die taxane enthalten und ihre therapeutische anwendung
HUP0200756A3 (en) * 2000-02-02 2005-02-28 Univ Florida State Res Found C7 carbonate substituted taxanes as antitumor agents and pharmaceutical compositions containing them
JP2003522171A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのc10カーボネート置換タキサン
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US7390898B2 (en) * 2002-08-02 2008-06-24 Immunogen Inc. Cytotoxic agents containing novel potent taxanes and their therapeutic use
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JP2006513152A (ja) * 2002-10-09 2006-04-20 ファイトジェン ライフ サイエンシズ インコーポレイテッド 新規タキサンならびにその使用および調製に関する方法
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US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
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US20100137221A1 (en) * 2007-02-27 2010-06-03 University Utah Research Foundation Peptides that interact with topoisomerase i and methods thereof
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KR101764081B1 (ko) 2008-04-30 2017-08-01 이뮤노젠 아이엔씨 가교제 및 그 용도
KR20190049930A (ko) 2008-05-23 2019-05-09 더 유니버시티 오브 브리티쉬 콜롬비아 리포좀 나노입자에 사용하기 위한 변형된 약물
CN101838281B (zh) * 2010-05-20 2015-02-18 上海博速医药科技有限公司 一种多西他赛手性侧链中间体的制备方法
CN103732229A (zh) 2011-08-02 2014-04-16 安斯泰来制药株式会社 基于药剂的联用的癌症治疗方法
RU2632108C2 (ru) 2011-12-08 2017-10-02 Биотест Аг Применения иммуноконъюгатов, мишенью которых является cd138
CN105849086B (zh) 2012-11-24 2018-07-31 杭州多禧生物科技有限公司 亲水性链接体及其在药物分子和细胞结合分子共轭反应上的应用
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CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物
CN114262344A (zh) 2014-02-28 2022-04-01 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
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FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
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US5015722A (en) * 1990-04-04 1991-05-14 Hoechst Celanese Corporation Melt-processable polyester capable of forming an anisotropic melt which exhibits a highly attractive balance between its molding and heat deflection temperatures
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
IT1254517B (it) * 1992-03-06 1995-09-25 Indena Spa 14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
FR2698363B1 (fr) * 1992-11-23 1994-12-30 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent.
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Also Published As

Publication number Publication date
EP0690856A1 (en) 1996-01-10
CN1123547A (zh) 1996-05-29
JPH11322737A (ja) 1999-11-24
EP0690856B1 (en) 2002-12-04
HUT73848A (en) 1996-09-30
JP3145993B2 (ja) 2001-03-12
EP0690856A4 (pt) 1996-02-07
RU2137764C1 (ru) 1999-09-20
DK0690856T3 (da) 2003-03-31
NO311722B1 (no) 2002-01-14
PL180708B1 (pl) 2001-03-30
NO953796D0 (no) 1995-09-25
JP3157165B2 (ja) 2001-04-16
KR100223720B1 (ko) 1999-10-15
US5599820A (en) 1997-02-04
CA2158147A1 (en) 1994-10-13
CZ248095A3 (en) 1996-03-13
ES2190440T3 (es) 2003-08-01
ATE229018T1 (de) 2002-12-15
US5475011A (en) 1995-12-12
AU6491694A (en) 1994-10-24
HU9502642D0 (en) 1995-11-28
JPH08508497A (ja) 1996-09-10
WO1994022856A1 (en) 1994-10-13
SK282317B6 (sk) 2002-01-07
AU676041B2 (en) 1997-02-27
CA2158147C (en) 1999-10-05
DE69431833D1 (de) 2003-01-16
NO953796L (no) 1995-11-15
US5705508A (en) 1998-01-06
DE69431833T2 (de) 2003-11-06
CN1067682C (zh) 2001-06-27
SK118395A3 (en) 1996-06-05
CZ288924B6 (cs) 2001-09-12
PL310827A1 (en) 1996-01-08
PL179587B1 (pl) 2000-09-29
KR960701045A (ko) 1996-02-24

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