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KR960701045A - 항종양 화합물, 약제학적 조성물, 그의 제조방법 및 치료방법(anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment) - Google Patents

항종양 화합물, 약제학적 조성물, 그의 제조방법 및 치료방법(anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment)

Info

Publication number
KR960701045A
KR960701045A KR1019950704147A KR19950704147A KR960701045A KR 960701045 A KR960701045 A KR 960701045A KR 1019950704147 A KR1019950704147 A KR 1019950704147A KR 19950704147 A KR19950704147 A KR 19950704147A KR 960701045 A KR960701045 A KR 960701045A
Authority
KR
South Korea
Prior art keywords
treatment
pharmaceutical compositions
preparation
methods
tumor compounds
Prior art date
Application number
KR1019950704147A
Other languages
English (en)
Other versions
KR100223720B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to KR1019980709593A priority Critical patent/KR100223114B1/ko
Publication of KR960701045A publication Critical patent/KR960701045A/ko
Application granted granted Critical
Publication of KR100223720B1 publication Critical patent/KR100223720B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
KR1019950704147A 1993-03-26 1994-03-24 항종양화합물 및 그 제조방법 KR100223720B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019980709593A KR100223114B1 (ko) 1993-03-26 1994-03-24 항종양화합물,그제조방법및용도

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/040,189 US5475011A (en) 1993-03-26 1993-03-26 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US8/040189 1993-03-26
PCT/US1994/003215 WO1994022856A1 (en) 1993-03-26 1994-03-24 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1019980709593A Division KR100223114B1 (ko) 1993-03-26 1994-03-24 항종양화합물,그제조방법및용도

Publications (2)

Publication Number Publication Date
KR960701045A true KR960701045A (ko) 1996-02-24
KR100223720B1 KR100223720B1 (ko) 1999-10-15

Family

ID=21909617

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950704147A KR100223720B1 (ko) 1993-03-26 1994-03-24 항종양화합물 및 그 제조방법

Country Status (19)

Country Link
US (3) US5475011A (ko)
EP (1) EP0690856B1 (ko)
JP (2) JP3157165B2 (ko)
KR (1) KR100223720B1 (ko)
CN (1) CN1067682C (ko)
AT (1) ATE229018T1 (ko)
AU (1) AU676041B2 (ko)
CA (1) CA2158147C (ko)
CZ (1) CZ288924B6 (ko)
DE (1) DE69431833T2 (ko)
DK (1) DK0690856T3 (ko)
ES (1) ES2190440T3 (ko)
HU (1) HUT73848A (ko)
NO (1) NO311722B1 (ko)
PL (2) PL179587B1 (ko)
PT (1) PT690856E (ko)
RU (1) RU2137764C1 (ko)
SK (1) SK282317B6 (ko)
WO (1) WO1994022856A1 (ko)

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US6335362B1 (en) * 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
FR2718137B1 (fr) * 1994-04-05 1996-04-26 Rhone Poulenc Rorer Sa Procédé de préparation de trialcoylsilyl-7 baccatine III.
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IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
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US5807888A (en) * 1995-12-13 1998-09-15 Xechem International, Inc. Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US5854278A (en) * 1995-12-13 1998-12-29 Xechem International, Inc. Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US6177456B1 (en) 1995-10-02 2001-01-23 Xechem International, Inc. Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
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EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
DE60032633T2 (de) * 1999-11-24 2007-10-04 Immunogen Inc., Cambridge Zytotoxische mittel, die taxane enthalten und ihre therapeutische anwendung
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KR101764081B1 (ko) 2008-04-30 2017-08-01 이뮤노젠 아이엔씨 가교제 및 그 용도
KR20190049930A (ko) 2008-05-23 2019-05-09 더 유니버시티 오브 브리티쉬 콜롬비아 리포좀 나노입자에 사용하기 위한 변형된 약물
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CN103732229A (zh) 2011-08-02 2014-04-16 安斯泰来制药株式会社 基于药剂的联用的癌症治疗方法
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CN105849086B (zh) 2012-11-24 2018-07-31 杭州多禧生物科技有限公司 亲水性链接体及其在药物分子和细胞结合分子共轭反应上的应用
JP6100627B2 (ja) * 2013-06-24 2017-03-22 株式会社パイロットコーポレーション 熱消色性筆記具インキ組成物及びそれを内蔵した筆記具
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物
CN114262344A (zh) 2014-02-28 2022-04-01 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
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KR102459468B1 (ko) 2016-11-14 2022-10-26 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
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FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
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IT1254517B (it) * 1992-03-06 1995-09-25 Indena Spa 14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
FR2698363B1 (fr) * 1992-11-23 1994-12-30 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent.
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Also Published As

Publication number Publication date
EP0690856A1 (en) 1996-01-10
CN1123547A (zh) 1996-05-29
JPH11322737A (ja) 1999-11-24
EP0690856B1 (en) 2002-12-04
HUT73848A (en) 1996-09-30
JP3145993B2 (ja) 2001-03-12
EP0690856A4 (ko) 1996-02-07
RU2137764C1 (ru) 1999-09-20
DK0690856T3 (da) 2003-03-31
PT690856E (pt) 2003-04-30
NO311722B1 (no) 2002-01-14
PL180708B1 (pl) 2001-03-30
NO953796D0 (no) 1995-09-25
JP3157165B2 (ja) 2001-04-16
KR100223720B1 (ko) 1999-10-15
US5599820A (en) 1997-02-04
CA2158147A1 (en) 1994-10-13
CZ248095A3 (en) 1996-03-13
ES2190440T3 (es) 2003-08-01
ATE229018T1 (de) 2002-12-15
US5475011A (en) 1995-12-12
AU6491694A (en) 1994-10-24
HU9502642D0 (en) 1995-11-28
JPH08508497A (ja) 1996-09-10
WO1994022856A1 (en) 1994-10-13
SK282317B6 (sk) 2002-01-07
AU676041B2 (en) 1997-02-27
CA2158147C (en) 1999-10-05
DE69431833D1 (de) 2003-01-16
NO953796L (no) 1995-11-15
US5705508A (en) 1998-01-06
DE69431833T2 (de) 2003-11-06
CN1067682C (zh) 2001-06-27
SK118395A3 (en) 1996-06-05
CZ288924B6 (cs) 2001-09-12
PL310827A1 (en) 1996-01-08
PL179587B1 (pl) 2000-09-29

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