PT3723815T - Ligandos psma para imagiologia e endorradioterapia - Google Patents

Ligandos psma para imagiologia e endorradioterapia

Info

Publication number: PT3723815T
Authority: PT; Portugal
Prior art keywords: ligads; endoradiotherapy; psma; imaging; psma ligads
Prior art date: 2017-12-11

Application number

PT188122154T

Other languages

English (en)

Original Assignee

Univ Muenchen Tech

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-12-11

Filing date

2018-12-11

Publication date

2022-05-30

2018-12-11 Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech

2022-05-30 Publication of PT3723815T publication Critical patent/PT3723815T/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Optics & Photonics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nuclear Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT188122154T 2017-12-11 2018-12-11 Ligandos psma para imagiologia e endorradioterapia PT3723815T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP17206510		2017-12-11

Publications (1)

Publication Number	Publication Date
PT3723815T true PT3723815T (pt)	2022-05-30

Family

ID=60654872

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT188122154T PT3723815T (pt)	2017-12-11	2018-12-11	Ligandos psma para imagiologia e endorradioterapia
PT212181804T PT4008359T (pt)	2017-12-11	2018-12-11	Ligandos psma para imagiologia e endorradioterapia

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT212181804T PT4008359T (pt)	2017-12-11	2018-12-11	Ligandos psma para imagiologia e endorradioterapia

Country Status (32)

Country	Link
US (2)	US11497819B2 (pt)
EP (3)	EP3723815B1 (pt)
JP (3)	JP7317375B2 (pt)
KR (1)	KR20200097690A (pt)
CN (2)	CN116617421A (pt)
AU (2)	AU2018382479B2 (pt)
BR (1)	BR112020011727A2 (pt)
CA (1)	CA3078104A1 (pt)
CL (1)	CL2020001542A1 (pt)
CR (1)	CR20200241A (pt)
CU (1)	CU24677B1 (pt)
DK (2)	DK3723815T3 (pt)
EC (1)	ECSP20029142A (pt)
ES (2)	ES2997266T3 (pt)
FI (1)	FI4008359T3 (pt)
HR (2)	HRP20220764T1 (pt)
HU (1)	HUE059083T2 (pt)
IL (2)	IL274072B2 (pt)
JO (1)	JOP20200135A1 (pt)
LT (2)	LT4008359T (pt)
MX (2)	MX2020005430A (pt)
PE (1)	PE20210456A1 (pt)
PL (1)	PL3723815T3 (pt)
PT (2)	PT3723815T (pt)
RS (2)	RS63279B1 (pt)
SG (1)	SG11202002965WA (pt)
SI (1)	SI3723815T1 (pt)
SM (1)	SMT202400439T1 (pt)
TN (1)	TN2020000072A1 (pt)
UA (1)	UA126413C2 (pt)
WO (1)	WO2019115547A1 (pt)
ZA (1)	ZA202003472B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT3723815T (pt)	2017-12-11	2022-05-30	Univ Muenchen Tech	Ligandos psma para imagiologia e endorradioterapia
EA202192045A1 (ru)	2019-01-30	2021-10-27	Технише Универзитет Мюнхен	Средства для диагностической визуализации ракового заболевания
PL3917626T3 (pl) *	2019-01-30	2023-11-27	Technische Universität München	Dwutrybowy radioznacznik i terapeutyk wiążący psma
CA3144094A1 (en)	2019-06-21	2020-12-24	Provincial Health Services Authority	Radiolabeled compounds targeting the prostate-specific membrane antigen
CN112321673B (zh) *	2020-11-04	2022-09-20	北京市肿瘤防治研究所	一种前列腺特异性膜抗原靶向抑制剂及应用和探针
CN113354707A (zh) *	2021-06-07	2021-09-07	苏州思萃同位素技术研究所有限公司	一种针对前列腺癌的三功能诊疗一体化药物前体的合成方法及其产品
WO2023173074A2 (en) *	2022-03-10	2023-09-14	The Research Foundation For The State University Of New York	Immunostimulant-cytotoxic conjugate composition and methods for cancer treatment
CN115010629B (zh) *	2022-06-07	2024-02-23	西南医科大学附属医院	前列腺特异性膜抗原抑制剂、其核素标记物及制法和应用
WO2025022285A2 (en)	2023-07-21	2025-01-30	Novartis Ag	Psma-targeting radioligand treatment regimen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200716632A (en)	2005-05-16	2007-05-01	Gilead Sciences Inc	Integrase inhibitor compounds
CA2987744C (en) *	2008-08-01	2022-11-15	The Johns Hopkins University	Psma-binding agents and uses thereof
WO2010135431A2 (en) *	2009-05-19	2010-11-25	The Regents Of The University Of California	Compositions, devices, and methods related to prostate-specific membrane antigen
DE202014011593U1 (de) *	2013-10-18	2023-08-23	Novartis Ag	Markierte Inhibitoren des prostataspezifischen Membranantigens (PSMA), deren Verwendung als bildgebende Mittel und pharmazeutische Wirkstoffe für die Behandlung von Prostatakrebs
JP6749249B2 (ja)	2014-05-06	2020-09-02	ザジョンズホプキンズユニヴァーシティー	Ｐｓｍａを標的としたイメージング及び放射線治療のための金属／放射性金属標識ｐｓｍａ阻害剤
US10688200B2 (en)	2015-12-31	2020-06-23	Five Eleven Pharma Inc.	Urea-based prostate specific membrane antigen (PSMA) inhibitors for imaging and therapy
US11458213B2 (en) *	2016-03-22	2022-10-04	The Johns Hopkins University	Prostate-specific membrane antigen targeted high-affinity agents for endoradiotherapy of prostate cancer
TW201930265A (zh)	2017-12-11	2019-08-01	西班牙商阿爾米雷爾有限公司	作為acc抑制劑的吡咯衍生物
EP3724176B1 (en)	2017-12-11	2022-01-26	Helsinn Healthcare SA	Fumarate salt of (r)-3-(1-(2,3-dichloro-4-(pyrazin-2-yl)phenyl)-2,2,2-trifluoroethyl)-1-methyl-1-(1-methylpiperidin-4-yl) urea, methods of preparation, and uses thereof
PT3723815T (pt)	2017-12-11	2022-05-30	Univ Muenchen Tech	Ligandos psma para imagiologia e endorradioterapia

2018
- 2018-12-11 PT PT188122154T patent/PT3723815T/pt unknown
- 2018-12-11 DK DK18812215.4T patent/DK3723815T3/da active
- 2018-12-11 PT PT212181804T patent/PT4008359T/pt unknown
- 2018-12-11 KR KR1020207014036A patent/KR20200097690A/ko not_active Application Discontinuation
- 2018-12-11 LT LTEP21218180.4T patent/LT4008359T/lt unknown
- 2018-12-11 JP JP2020526146A patent/JP7317375B2/ja active Active
- 2018-12-11 SM SM20240439T patent/SMT202400439T1/it unknown
- 2018-12-11 CN CN202310801735.3A patent/CN116617421A/zh active Pending
- 2018-12-11 MX MX2020005430A patent/MX2020005430A/es unknown
- 2018-12-11 WO PCT/EP2018/084399 patent/WO2019115547A1/en active Application Filing
- 2018-12-11 ES ES21218180T patent/ES2997266T3/es active Active
- 2018-12-11 FI FIEP21218180.4T patent/FI4008359T3/fi active
- 2018-12-11 US US16/765,729 patent/US11497819B2/en active Active
- 2018-12-11 IL IL274072A patent/IL274072B2/en unknown
- 2018-12-11 PE PE2020000552A patent/PE20210456A1/es unknown
- 2018-12-11 DK DK21218180.4T patent/DK4008359T3/da active
- 2018-12-11 RS RS20220527A patent/RS63279B1/sr unknown
- 2018-12-11 PL PL18812215.4T patent/PL3723815T3/pl unknown
- 2018-12-11 HR HRP20220764TT patent/HRP20220764T1/hr unknown
- 2018-12-11 BR BR112020011727-7A patent/BR112020011727A2/pt unknown
- 2018-12-11 CR CR20200241A patent/CR20200241A/es unknown
- 2018-12-11 RS RS20241176A patent/RS66086B1/sr unknown
- 2018-12-11 IL IL313103A patent/IL313103A/en unknown
- 2018-12-11 TN TNP/2020/000072A patent/TN2020000072A1/en unknown
- 2018-12-11 SG SG11202002965WA patent/SG11202002965WA/en unknown
- 2018-12-11 HR HRP20241453TT patent/HRP20241453T1/hr unknown
- 2018-12-11 SI SI201830691T patent/SI3723815T1/sl unknown
- 2018-12-11 HU HUE18812215A patent/HUE059083T2/hu unknown
- 2018-12-11 EP EP18812215.4A patent/EP3723815B1/en active Active
- 2018-12-11 AU AU2018382479A patent/AU2018382479B2/en active Active
- 2018-12-11 CA CA3078104A patent/CA3078104A1/en active Pending
- 2018-12-11 JO JOP/2020/0135A patent/JOP20200135A1/ar unknown
- 2018-12-11 ES ES18812215T patent/ES2914832T3/es active Active
- 2018-12-11 EP EP24198677.7A patent/EP4464341A3/en active Pending
- 2018-12-11 UA UAA202003533A patent/UA126413C2/uk unknown
- 2018-12-11 EP EP21218180.4A patent/EP4008359B1/en active Active
- 2018-12-11 LT LTEPPCT/EP2018/084399T patent/LT3723815T/lt unknown
- 2018-12-11 CN CN201880056196.2A patent/CN111182927B/zh active Active
- 2018-12-11 CU CU2020000052A patent/CU24677B1/es unknown
2020
- 2020-06-03 EC ECSENADI202029142A patent/ECSP20029142A/es unknown
- 2020-06-10 ZA ZA2020/03472A patent/ZA202003472B/en unknown
- 2020-06-10 CL CL2020001542A patent/CL2020001542A1/es unknown
- 2020-07-13 MX MX2023005053A patent/MX2023005053A/es unknown
2022
- 2022-07-15 US US17/866,034 patent/US20230122957A1/en active Pending
2023
- 2023-07-11 JP JP2023113523A patent/JP7572080B2/ja active Active
2024
- 2024-10-03 JP JP2024173980A patent/JP2025011169A/ja active Pending
2025
- 2025-02-07 AU AU2025200837A patent/AU2025200837A1/en active Pending

Also Published As

Publication number	Publication date
CN116617421A (zh)	2023-08-22
MX2020005430A (es)	2020-08-27
BR112020011727A2 (pt)	2020-11-17
EP4008359A1 (en)	2022-06-08
JP2025011169A (ja)	2025-01-23
SMT202400439T1 (it)	2024-11-15
IL274072B1 (en)	2024-07-01
SI3723815T1 (sl)	2022-07-29
US11497819B2 (en)	2022-11-15
TN2020000072A1 (en)	2022-01-06
JP2023139063A (ja)	2023-10-03
EP4008359B1 (en)	2024-09-11
MX2023005053A (es)	2023-05-17
RU2020116158A (ru)	2022-01-13
CN111182927A (zh)	2020-05-19
RS63279B1 (sr)	2022-06-30
AU2025200837A1 (en)	2025-02-27
ES2997266T3 (en)	2025-02-14
EP4464341A2 (en)	2024-11-20
PT4008359T (pt)	2024-10-25
LT3723815T (lt)	2022-07-25
HUE059083T2 (hu)	2022-10-28
EP3723815B1 (en)	2022-04-20
EP4464341A3 (en)	2025-01-22
JOP20200135A1 (ar)	2020-06-02
IL274072B2 (en)	2024-11-01
WO2019115547A1 (en)	2019-06-20
HRP20220764T1 (hr)	2022-09-16
IL274072A (en)	2020-06-30
IL313103A (en)	2024-07-01
HRP20241453T1 (hr)	2024-12-20
FI4008359T3 (fi)	2024-11-11
CN111182927B (zh)	2023-07-21
CU20200052A7 (es)	2021-03-11
ES2914832T3 (es)	2022-06-16
LT4008359T (lt)	2024-12-27
JP7572080B2 (ja)	2024-10-23
US20200297876A1 (en)	2020-09-24
ECSP20029142A (es)	2020-09-30
RS66086B1 (sr)	2024-11-29
CU24677B1 (es)	2023-09-07
KR20200097690A (ko)	2020-08-19
DK3723815T3 (da)	2022-07-11
US20230122957A1 (en)	2023-04-20
CL2020001542A1 (es)	2020-10-02
AU2018382479A1 (en)	2020-04-16
SG11202002965WA (en)	2020-04-29
JP7317375B2 (ja)	2023-07-31
CA3078104A1 (en)	2019-06-20
EP3723815A1 (en)	2020-10-21
DK4008359T3 (da)	2024-10-14
JP2021505532A (ja)	2021-02-18
CR20200241A (es)	2020-09-21
PL3723815T3 (pl)	2022-07-18
AU2018382479B2 (en)	2024-11-07
ZA202003472B (en)	2022-06-29
UA126413C2 (uk)	2022-09-28
PE20210456A1 (es)	2021-03-08

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