PT2198886E - Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis sob movimentação - Google Patents
Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis sob movimentação Download PDFInfo
- Publication number
- PT2198886E PT2198886E PT10001518T PT10001518T PT2198886E PT 2198886 E PT2198886 E PT 2198886E PT 10001518 T PT10001518 T PT 10001518T PT 10001518 T PT10001518 T PT 10001518T PT 2198886 E PT2198886 E PT 2198886E
- Authority
- PT
- Portugal
- Prior art keywords
- blood
- motion
- flexible containers
- exposure bag
- inactivating pathogens
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 239000012141 concentrate Substances 0.000 title 1
- 210000003743 erythrocyte Anatomy 0.000 title 1
- 230000000415 inactivating effect Effects 0.000 title 1
- 244000052769 pathogen Species 0.000 title 1
- 210000002381 plasma Anatomy 0.000 title 1
- 238000002428 photodynamic therapy Methods 0.000 abstract 2
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 abstract 1
- 108010076830 Thionins Proteins 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 229960000907 methylthioninium chloride Drugs 0.000 abstract 1
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical compound N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 abstract 1
- 229950003937 tolonium Drugs 0.000 abstract 1
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
- A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultraviolet radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005062634A DE102005062634A1 (de) | 2005-12-23 | 2005-12-23 | Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2198886E true PT2198886E (pt) | 2011-09-28 |
Family
ID=38043033
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT06840887T PT1962905E (pt) | 2005-12-23 | 2006-12-21 | Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis por agitação |
PT10001518T PT2198886E (pt) | 2005-12-23 | 2006-12-21 | Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis sob movimentação |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT06840887T PT1962905E (pt) | 2005-12-23 | 2006-12-21 | Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis por agitação |
Country Status (17)
Country | Link |
---|---|
US (2) | US8164073B2 (pt) |
EP (2) | EP2198886B1 (pt) |
JP (1) | JP5232008B2 (pt) |
KR (1) | KR101499735B1 (pt) |
CN (1) | CN101340930B (pt) |
AT (2) | ATE514432T1 (pt) |
AU (1) | AU2006332291B2 (pt) |
CA (1) | CA2632558C (pt) |
DE (2) | DE102005062634A1 (pt) |
DK (2) | DK2198886T3 (pt) |
ES (2) | ES2341368T3 (pt) |
HK (3) | HK1121406A1 (pt) |
PL (2) | PL1962905T3 (pt) |
PT (2) | PT1962905E (pt) |
RU (1) | RU2466742C2 (pt) |
SI (2) | SI1962905T1 (pt) |
WO (1) | WO2007076832A1 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005062410A1 (de) | 2005-12-23 | 2007-08-09 | Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. | Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht |
DE102005062634A1 (de) | 2005-12-23 | 2007-06-28 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH | Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung |
EP1902740A1 (en) | 2006-09-19 | 2008-03-26 | Maco Pharma S.A. | Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system |
EP2008669A1 (en) | 2007-06-22 | 2008-12-31 | Maco Pharma S.A. | Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process |
PL2459248T3 (pl) * | 2009-06-02 | 2020-01-31 | Biolitec Unternehmensbeteiligungs Ii Ag | Nowy sposób zmniejszania liczby drobnoustrojów w ludzkiej krwi i produktach krwiopochodnych z użyciem przeciwdrobnoustrojowej terapii fotodynamicznej |
GB201006753D0 (en) | 2010-04-22 | 2010-06-09 | Biotest Ag | Process for preparing an immunolobulin composition |
US20210392873A1 (en) | 2011-03-15 | 2021-12-23 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
US8883409B1 (en) * | 2013-12-08 | 2014-11-11 | Hemalux LLC | Method of reducing pathogens in whole blood by illuminating with ultraviolet light under low oxygen conditions |
CN107833751A (zh) * | 2017-10-27 | 2018-03-23 | 吉林化工学院 | 一种复合膜电极制备方法及光电性质检测方法 |
US11964092B2 (en) | 2019-03-11 | 2024-04-23 | ABC Med Tech Corp. | Portable centrifuge and method of use |
WO2020252148A1 (en) * | 2019-06-11 | 2020-12-17 | Paragonix Technologies, Inc. | Organ transport container with antiviral therapy |
CA3153723A1 (en) * | 2019-09-24 | 2021-04-01 | ABC Med Tech Corp. | Centrifuge device and method of use |
US20210338860A1 (en) | 2020-05-01 | 2021-11-04 | Uv Innovators, Llc | Ultraviolet (uv) light emission device employing visible light for operation guidance, and related methods of use, particularly suited for decontamination |
FR3117872A1 (fr) * | 2020-12-21 | 2022-06-24 | Maco Pharma | Procédé et système pour produire des cellules mononucléées apoptotiques |
DE102021119408A1 (de) * | 2021-07-27 | 2023-02-02 | Blutspendedienst der Landesverbände des DRK in Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen g.G.m.b.H. | Additivlösung für Erythrozytenkonzentrate |
CN115350296A (zh) * | 2022-08-30 | 2022-11-18 | 南京双威生物医学科技有限公司 | 基于核黄素光化学法的血液病原体灭活处理系统 |
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US4469227A (en) | 1983-08-17 | 1984-09-04 | Clifford Faust | Package for cryogenically frozen liquids |
US4586928A (en) | 1984-10-09 | 1986-05-06 | Miles Laboratories, Inc. | Pivoting frangible valve for plastic bags |
US4952812A (en) | 1986-08-26 | 1990-08-28 | Baxter International Inc. | Irradiation of blood products |
US4878891A (en) | 1987-06-25 | 1989-11-07 | Baylor Research Foundation | Method for eradicating infectious biological contaminants in body tissues |
GB8807380D0 (en) * | 1988-03-29 | 1988-05-05 | Gunn A | Blood processing apparatus |
US5661126A (en) * | 1989-01-19 | 1997-08-26 | The General Hospital Corporation | Use of mullerian inhibiting substance for treating certain tumors and for modulating class I major histocompatibility antigen expression |
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EP0516836B1 (en) * | 1990-12-20 | 1996-03-13 | Baxter International Inc. | A device and method for eradicating contaminants in fluids |
JPH05131018A (ja) | 1991-11-11 | 1993-05-28 | Terumo Corp | バツグ連結体およびその製造方法 |
US6420570B1 (en) * | 1993-06-28 | 2002-07-16 | Cerus Corporation | Psoralen compounds |
US5625079A (en) * | 1993-06-28 | 1997-04-29 | Cerus Corporation | Synthesizing psoralen compounds useful as intermediates |
JP3677287B2 (ja) | 1993-11-10 | 2005-07-27 | セラス コーポレーション | 光活性化のための装置および方法 |
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US6576201B1 (en) * | 2000-01-28 | 2003-06-10 | Baxter International Inc. | Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation |
AU2001296309A1 (en) | 2000-09-27 | 2002-04-08 | Gambro, Inc | Inactivation of contaminants using photosensitizers and pulsed light |
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US20030127603A1 (en) * | 2001-05-15 | 2003-07-10 | Bernard Horowitz | Apparatus for the inactivation of pathogens in protein-containing fluids and uses thereof |
US20030064001A1 (en) | 2001-05-17 | 2003-04-03 | Fries William M. | System for the decontamination of fluid products using light |
US20030228564A1 (en) | 2001-05-30 | 2003-12-11 | Edrich Richard Alan | Nitric oxide in a pathogen inactivation process |
JP2005503870A (ja) * | 2001-09-27 | 2005-02-10 | ガンブロ、 インコーポレイテッド | 体外血液処理に使用する高周波または電磁気情報装置および方法 |
DE10152159A1 (de) | 2001-10-25 | 2003-05-15 | Aventis Behring Gmbh | Verfahren zur proteinschonenden Reinigung von kontaminierten biologischen Flüssigkeiten |
JP4704684B2 (ja) * | 2002-02-01 | 2011-06-15 | カリディアンビーシーティ バイオテクノロジーズ,エルエルシー | 光増感剤および光のピーク波長を使用する血液および血液製剤中の汚染の減少 |
AU2002306757B2 (en) | 2002-04-12 | 2009-07-02 | Throwleigh Technologies, L.L.C. | Methods and apparatus for decontaminating fluids |
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US7207964B2 (en) | 2003-03-17 | 2007-04-24 | Hemavation, Llc | Apparatus and method for down-regulating immune system mediators in blood |
WO2005115357A2 (en) * | 2004-05-14 | 2005-12-08 | Hans-Dietrich Polaschegg | Taurolidine formulations and delivery |
US8296071B2 (en) * | 2004-03-15 | 2012-10-23 | Terumo Bct Biotechnologies, Llc | Methods for uniformly treating biological samples with electromagnetic radiation |
FR2887335B1 (fr) | 2005-06-21 | 2007-08-10 | Maco Pharma Sa | Procede pour la determination d'une contamination pathogene dans un fluide contenant des plaquettes sanguines |
DE102005062634A1 (de) | 2005-12-23 | 2007-06-28 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH | Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung |
DE102005062410A1 (de) | 2005-12-23 | 2007-08-09 | Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. | Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht |
EP1902740A1 (en) * | 2006-09-19 | 2008-03-26 | Maco Pharma S.A. | Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system |
EP2008669A1 (en) * | 2007-06-22 | 2008-12-31 | Maco Pharma S.A. | Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process |
-
2005
- 2005-12-23 DE DE102005062634A patent/DE102005062634A1/de not_active Withdrawn
-
2006
- 2006-12-21 US US11/643,728 patent/US8164073B2/en active Active
- 2006-12-21 CA CA2632558A patent/CA2632558C/en active Active
- 2006-12-21 PT PT06840887T patent/PT1962905E/pt unknown
- 2006-12-21 CN CN2006800479151A patent/CN101340930B/zh active Active
- 2006-12-21 DE DE502006006204T patent/DE502006006204D1/de active Active
- 2006-12-21 WO PCT/DE2006/002307 patent/WO2007076832A1/de active Application Filing
- 2006-12-21 AT AT10001518T patent/ATE514432T1/de active
- 2006-12-21 SI SI200630632T patent/SI1962905T1/sl unknown
- 2006-12-21 JP JP2008546124A patent/JP5232008B2/ja active Active
- 2006-12-21 DK DK10001518.9T patent/DK2198886T3/da active
- 2006-12-21 RU RU2008129480/14A patent/RU2466742C2/ru active
- 2006-12-21 DK DK06840887.1T patent/DK1962905T3/da active
- 2006-12-21 KR KR1020087017172A patent/KR101499735B1/ko active Active
- 2006-12-21 ES ES06840887T patent/ES2341368T3/es active Active
- 2006-12-21 ES ES10001518T patent/ES2369059T3/es active Active
- 2006-12-21 SI SI200631112T patent/SI2198886T1/sl unknown
- 2006-12-21 AU AU2006332291A patent/AU2006332291B2/en active Active
- 2006-12-21 PL PL06840887T patent/PL1962905T3/pl unknown
- 2006-12-21 EP EP10001518A patent/EP2198886B1/de active Active
- 2006-12-21 AT AT06840887T patent/ATE457739T1/de active
- 2006-12-21 PT PT10001518T patent/PT2198886E/pt unknown
- 2006-12-21 EP EP06840887A patent/EP1962905B1/de active Active
- 2006-12-21 PL PL10001518T patent/PL2198886T3/pl unknown
-
2009
- 2009-03-03 HK HK09101974.9A patent/HK1121406A1/xx unknown
- 2009-03-03 HK HK09101975.8A patent/HK1121407A1/xx unknown
-
2010
- 2010-11-16 HK HK10110638.5A patent/HK1144249A1/xx unknown
-
2012
- 2012-03-14 US US13/419,778 patent/US8525128B2/en active Active
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