PT1173178E - Composicao compreendendo apomorfina e sildenafil e utilizacao da mesma para o tratamento da disfuncao erectil - Google Patents
Composicao compreendendo apomorfina e sildenafil e utilizacao da mesma para o tratamento da disfuncao erectilInfo
- Publication number
- PT1173178E PT1173178E PT00916324T PT00916324T PT1173178E PT 1173178 E PT1173178 E PT 1173178E PT 00916324 T PT00916324 T PT 00916324T PT 00916324 T PT00916324 T PT 00916324T PT 1173178 E PT1173178 E PT 1173178E
- Authority
- PT
- Portugal
- Prior art keywords
- apomorphine
- sildenafil
- treatment
- administered
- composition understanding
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/270,035 US6087362A (en) | 1999-03-16 | 1999-03-16 | Apomorphine and sildenafil composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1173178E true PT1173178E (pt) | 2005-11-30 |
Family
ID=23029614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00916324T PT1173178E (pt) | 1999-03-16 | 2000-03-14 | Composicao compreendendo apomorfina e sildenafil e utilizacao da mesma para o tratamento da disfuncao erectil |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6087362A (pt) |
| EP (1) | EP1173178B1 (pt) |
| JP (1) | JP2002539163A (pt) |
| CN (1) | CN1350454A (pt) |
| AT (1) | ATE302003T1 (pt) |
| AU (1) | AU3744500A (pt) |
| BR (1) | BR0009016A (pt) |
| CA (1) | CA2367605A1 (pt) |
| CZ (1) | CZ20013344A3 (pt) |
| DE (1) | DE60022021T2 (pt) |
| DK (1) | DK1173178T3 (pt) |
| ES (1) | ES2244418T3 (pt) |
| HU (1) | HUP0200549A3 (pt) |
| IL (1) | IL145487A0 (pt) |
| MX (1) | MXPA01009332A (pt) |
| NO (1) | NO324511B1 (pt) |
| NZ (1) | NZ514464A (pt) |
| PL (1) | PL350313A1 (pt) |
| PT (1) | PT1173178E (pt) |
| WO (1) | WO2000054774A1 (pt) |
| ZA (1) | ZA200107920B (pt) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040063719A1 (en) * | 1998-08-26 | 2004-04-01 | Queen's University At Kingston | Combination therapy using antihypertensive agents and endothelin antagonists |
| US6428769B1 (en) * | 1999-05-04 | 2002-08-06 | Aradigm Corporation | Acute testosterone administration |
| US20020013327A1 (en) * | 2000-04-18 | 2002-01-31 | Lee Andrew G. | Compositions and methods for treating female sexual dysfunction |
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| NZ524601A (en) * | 2000-08-30 | 2006-04-28 | Unimed Pharmaceuticals Inc | Method for treating erectile dysfunction and increasing libido in men |
| US20030139384A1 (en) * | 2000-08-30 | 2003-07-24 | Dudley Robert E. | Method for treating erectile dysfunction and increasing libido in men |
| US6821978B2 (en) | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
| US20020091129A1 (en) * | 2000-11-20 | 2002-07-11 | Mitradev Boolell | Treatment of premature ejaculation |
| JP2004520389A (ja) * | 2001-02-08 | 2004-07-08 | ファルマシア・コーポレーション | 性的不全の治療のための早期効果発現薬剤 |
| ES2180446B1 (es) * | 2001-07-02 | 2004-01-16 | Esteve Labor Dr | Empleo de derivados de acidos 2,5-dihidroxibencenosulfonicos en la elaboracion de un medicamento para potenciar el efecto de otros farmacos en el tratamiento de la disfuncion erectil. |
| US20030044458A1 (en) * | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
| CN1781920A (zh) * | 2001-08-28 | 2006-06-07 | 先灵公司 | 多环鸟嘌呤磷酸二酯酶v抑制剂 |
| US20030114469A1 (en) * | 2001-09-27 | 2003-06-19 | Cohen David Saul | Combinations |
| US20030216407A1 (en) * | 2002-01-31 | 2003-11-20 | Pfizer Inc. | Use of PDE5 inhibitors in the treatment of scarring |
| US20060004190A1 (en) * | 2002-03-19 | 2006-01-05 | Michael Holick | Glycoside and orthoester glycoside derivatives of apomorphine, analogs, and uses thereof |
| US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
| US7037257B1 (en) * | 2002-08-22 | 2006-05-02 | Koenig J Frank | Erectile dysfuction treatments comprising momentary vacuum therapy alone or with medications |
| TWI330529B (en) * | 2003-01-13 | 2010-09-21 | Horphag Res Luxembourg Holding Sa | A preparation for improving sperm quality or fertility,a kit comprising the same and uses thereof |
| GB0304636D0 (en) * | 2003-02-28 | 2003-04-02 | Britannia Pharmaceuticals Ltd | Pharmaceutical composition for nasal delivery |
| US7306812B2 (en) * | 2003-05-09 | 2007-12-11 | Cephalon, Inc. | Dissolvable backing layer for use with a transmucosal delivery device |
| US7276246B2 (en) * | 2003-05-09 | 2007-10-02 | Cephalon, Inc. | Dissolvable backing layer for use with a transmucosal delivery device |
| DE10325813B4 (de) * | 2003-06-06 | 2007-12-20 | Universitätsklinikum Freiburg | Prophylaxe und/oder Therapie bei der portalen Hypertonie |
| AU2005239962B2 (en) * | 2004-05-11 | 2011-07-07 | Eb Ip Lybrido B.V. | Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction |
| RS20070166A (en) * | 2004-10-20 | 2008-09-29 | Endorecherche Inc., | Sex steroid precursors alone or in combination with a selective estrogen receptor modulator... |
| TR201815853T4 (tr) | 2005-10-12 | 2018-11-21 | Besins Healthcare Sarl | Hipogonadizmin tedavisinde kullanıma yönelik geliştirilmiş testosteron jeli. |
| KR20090121315A (ko) * | 2007-02-12 | 2009-11-25 | 디엠아이 바이오사이언시스 인코포레이티드 | 조루 및 발기부전을 동시에 치료하는 방법 |
| DK2114147T3 (da) * | 2007-02-12 | 2012-06-25 | Dmi Biosciences Inc | Reduktion af bivirkninger af tramadol |
| US8741918B2 (en) | 2007-06-21 | 2014-06-03 | Veroscience Llc | Parenteral formulations of dopamine agonists |
| US20100035886A1 (en) | 2007-06-21 | 2010-02-11 | Veroscience, Llc | Parenteral formulations of dopamine agonists |
| GB0715285D0 (en) * | 2007-08-06 | 2007-09-12 | Britannia Pharmaceuticals Ltd | Improvements in or relating to powdered medicaments for nasal delivery |
| US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
| US9011864B2 (en) * | 2007-12-26 | 2015-04-21 | Biotest Ag | Method of decreasing cytotoxic side-effects and improving efficacy of immunoconjugates |
| RU2486203C2 (ru) * | 2007-12-26 | 2013-06-27 | Биотест Аг | Способы улучшения направленного воздействия на cd138-экспрессирующие опухолевые клетки и агенты для их осуществления |
| JP5990365B2 (ja) * | 2007-12-26 | 2016-09-14 | バイオテスト・アクチエンゲゼルシヤフト | Ｃｄ１３８を標的とする剤及びその使用 |
| WO2009080830A1 (en) * | 2007-12-26 | 2009-07-02 | Biotest Ag | Immunoconjugates targeting cd138 and uses thereof |
| US20090246298A1 (en) * | 2008-03-31 | 2009-10-01 | Ceola P. Steele | Viagra |
| US20100184722A1 (en) * | 2008-12-19 | 2010-07-22 | Shimoda Biotech (Pty) Ltd | Inclusion complexes of alpha-cyclodextrin and sildenafil salt |
| CA2761120A1 (en) * | 2009-05-06 | 2010-11-11 | Biotest Ag | Uses of immunoconjugates targeting cd138 |
| US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
| DK2442650T3 (en) | 2009-06-12 | 2015-12-07 | Cynapsus Therapeutics Inc | sublingual apomorphine |
| WO2012000634A1 (de) | 2010-06-29 | 2012-01-05 | Georg Bambach | Pharmazeutische zusammensetzung zur behandlung von erektiler dysfunktion |
| TWI462739B (zh) | 2010-11-02 | 2014-12-01 | Univ Kaohsiung Medical | Ｓｉｌｄｅｎａｆｉｌ－同族物四級銨哌嗪鹽類之製備及醫療用途 |
| CA3115370A1 (en) | 2010-12-16 | 2012-06-21 | Sunovion Pharmaceuticals Inc. | Sublingual films comprising apomorphine and an organic base |
| RU2632108C2 (ru) | 2011-12-08 | 2017-10-02 | Биотест Аг | Применения иммуноконъюгатов, мишенью которых является cd138 |
| CA3127926A1 (en) | 2015-04-21 | 2016-10-27 | Sunovion Pharmaceuticals Inc. | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
| WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256652A (en) * | 1987-11-12 | 1993-10-26 | Pharmedic Co. | Topical compositions and methods for treatment of male impotence |
| DE69514794T2 (de) * | 1994-04-22 | 2000-07-27 | Pentech Pharmaceuticals, Inc. | Sublinguale dosierungsformen enthaltend apomorphin zur verwendung bei der behandlung von erektiler dysfunktion |
| GB9612514D0 (en) * | 1996-06-14 | 1996-08-14 | Pfizer Ltd | Novel process |
| BR9809848A (pt) * | 1997-05-19 | 2000-06-27 | Zonagen Inc | Composição |
| US6037346A (en) * | 1997-10-28 | 2000-03-14 | Vivus, Inc. | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
| US6200591B1 (en) * | 1998-06-25 | 2001-03-13 | Anwar A. Hussain | Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction |
-
1999
- 1999-03-16 US US09/270,035 patent/US6087362A/en not_active Expired - Fee Related
-
2000
- 2000-03-14 CA CA002367605A patent/CA2367605A1/en not_active Abandoned
- 2000-03-14 DK DK00916324T patent/DK1173178T3/da active
- 2000-03-14 DE DE60022021T patent/DE60022021T2/de not_active Expired - Fee Related
- 2000-03-14 JP JP2000604850A patent/JP2002539163A/ja active Pending
- 2000-03-14 ES ES00916324T patent/ES2244418T3/es not_active Expired - Lifetime
- 2000-03-14 AT AT00916324T patent/ATE302003T1/de not_active IP Right Cessation
- 2000-03-14 EP EP00916324A patent/EP1173178B1/en not_active Expired - Lifetime
- 2000-03-14 PL PL00350313A patent/PL350313A1/xx not_active Application Discontinuation
- 2000-03-14 WO PCT/US2000/006654 patent/WO2000054774A1/en active IP Right Grant
- 2000-03-14 NZ NZ514464A patent/NZ514464A/xx unknown
- 2000-03-14 IL IL14548700A patent/IL145487A0/xx unknown
- 2000-03-14 CN CN00807580A patent/CN1350454A/zh active Pending
- 2000-03-14 PT PT00916324T patent/PT1173178E/pt unknown
- 2000-03-14 MX MXPA01009332A patent/MXPA01009332A/es active IP Right Grant
- 2000-03-14 HU HU0200549A patent/HUP0200549A3/hu unknown
- 2000-03-14 CZ CZ20013344A patent/CZ20013344A3/cs unknown
- 2000-03-14 AU AU37445/00A patent/AU3744500A/en not_active Abandoned
- 2000-03-14 BR BR0009016-6A patent/BR0009016A/pt not_active Application Discontinuation
-
2001
- 2001-09-17 NO NO20014519A patent/NO324511B1/no unknown
- 2001-09-26 ZA ZA200107920A patent/ZA200107920B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0009016A (pt) | 2002-04-16 |
| EP1173178A1 (en) | 2002-01-23 |
| ES2244418T3 (es) | 2005-12-16 |
| CA2367605A1 (en) | 2000-09-21 |
| CN1350454A (zh) | 2002-05-22 |
| JP2002539163A (ja) | 2002-11-19 |
| NZ514464A (en) | 2004-01-30 |
| HUP0200549A3 (en) | 2004-07-28 |
| MXPA01009332A (es) | 2002-06-21 |
| HUP0200549A2 (hu) | 2002-07-29 |
| NO324511B1 (no) | 2007-11-05 |
| DK1173178T3 (da) | 2005-11-07 |
| WO2000054774A1 (en) | 2000-09-21 |
| PL350313A1 (en) | 2002-12-02 |
| ATE302003T1 (de) | 2005-09-15 |
| CZ20013344A3 (cs) | 2002-08-14 |
| US6087362A (en) | 2000-07-11 |
| NO20014519L (no) | 2001-10-25 |
| EP1173178A4 (en) | 2002-09-04 |
| DE60022021T2 (de) | 2006-06-08 |
| AU3744500A (en) | 2000-10-04 |
| DE60022021D1 (de) | 2005-09-22 |
| IL145487A0 (en) | 2002-06-30 |
| NO20014519D0 (no) | 2001-09-17 |
| EP1173178B1 (en) | 2005-08-17 |
| ZA200107920B (en) | 2003-03-26 |
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