[go: up one dir, main page]

DK1173178T3 - Præparat, der omfatter apomorfin og sildenafil, og anvendelse deraf til behandling af erektil dysfunktion - Google Patents

Præparat, der omfatter apomorfin og sildenafil, og anvendelse deraf til behandling af erektil dysfunktion

Info

Publication number
DK1173178T3
DK1173178T3 DK00916324T DK00916324T DK1173178T3 DK 1173178 T3 DK1173178 T3 DK 1173178T3 DK 00916324 T DK00916324 T DK 00916324T DK 00916324 T DK00916324 T DK 00916324T DK 1173178 T3 DK1173178 T3 DK 1173178T3
Authority
DK
Denmark
Prior art keywords
apomorphine
sildenafil
treatment
administered
composition
Prior art date
Application number
DK00916324T
Other languages
Danish (da)
English (en)
Inventor
Ragab El-Rashidy
Original Assignee
Pentech Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentech Pharmaceuticals Inc filed Critical Pentech Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1173178T3 publication Critical patent/DK1173178T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00916324T 1999-03-16 2000-03-14 Præparat, der omfatter apomorfin og sildenafil, og anvendelse deraf til behandling af erektil dysfunktion DK1173178T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/270,035 US6087362A (en) 1999-03-16 1999-03-16 Apomorphine and sildenafil composition

Publications (1)

Publication Number Publication Date
DK1173178T3 true DK1173178T3 (da) 2005-11-07

Family

ID=23029614

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00916324T DK1173178T3 (da) 1999-03-16 2000-03-14 Præparat, der omfatter apomorfin og sildenafil, og anvendelse deraf til behandling af erektil dysfunktion

Country Status (21)

Country Link
US (1) US6087362A (pt)
EP (1) EP1173178B1 (pt)
JP (1) JP2002539163A (pt)
CN (1) CN1350454A (pt)
AT (1) ATE302003T1 (pt)
AU (1) AU3744500A (pt)
BR (1) BR0009016A (pt)
CA (1) CA2367605A1 (pt)
CZ (1) CZ20013344A3 (pt)
DE (1) DE60022021T2 (pt)
DK (1) DK1173178T3 (pt)
ES (1) ES2244418T3 (pt)
HU (1) HUP0200549A3 (pt)
IL (1) IL145487A0 (pt)
MX (1) MXPA01009332A (pt)
NO (1) NO324511B1 (pt)
NZ (1) NZ514464A (pt)
PL (1) PL350313A1 (pt)
PT (1) PT1173178E (pt)
WO (1) WO2000054774A1 (pt)
ZA (1) ZA200107920B (pt)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040063719A1 (en) * 1998-08-26 2004-04-01 Queen's University At Kingston Combination therapy using antihypertensive agents and endothelin antagonists
US6428769B1 (en) * 1999-05-04 2002-08-06 Aradigm Corporation Acute testosterone administration
US20020013327A1 (en) * 2000-04-18 2002-01-31 Lee Andrew G. Compositions and methods for treating female sexual dysfunction
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
NZ524601A (en) * 2000-08-30 2006-04-28 Unimed Pharmaceuticals Inc Method for treating erectile dysfunction and increasing libido in men
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US6821978B2 (en) 2000-09-19 2004-11-23 Schering Corporation Xanthine phosphodiesterase V inhibitors
US20020091129A1 (en) * 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
JP2004520389A (ja) * 2001-02-08 2004-07-08 ファルマシア・コーポレーション 性的不全の治療のための早期効果発現薬剤
ES2180446B1 (es) * 2001-07-02 2004-01-16 Esteve Labor Dr Empleo de derivados de acidos 2,5-dihidroxibencenosulfonicos en la elaboracion de un medicamento para potenciar el efecto de otros farmacos en el tratamiento de la disfuncion erectil.
US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
CN1781920A (zh) * 2001-08-28 2006-06-07 先灵公司 多环鸟嘌呤磷酸二酯酶v抑制剂
US20030114469A1 (en) * 2001-09-27 2003-06-19 Cohen David Saul Combinations
US20030216407A1 (en) * 2002-01-31 2003-11-20 Pfizer Inc. Use of PDE5 inhibitors in the treatment of scarring
US20060004190A1 (en) * 2002-03-19 2006-01-05 Michael Holick Glycoside and orthoester glycoside derivatives of apomorphine, analogs, and uses thereof
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
US7037257B1 (en) * 2002-08-22 2006-05-02 Koenig J Frank Erectile dysfuction treatments comprising momentary vacuum therapy alone or with medications
TWI330529B (en) * 2003-01-13 2010-09-21 Horphag Res Luxembourg Holding Sa A preparation for improving sperm quality or fertility,a kit comprising the same and uses thereof
GB0304636D0 (en) * 2003-02-28 2003-04-02 Britannia Pharmaceuticals Ltd Pharmaceutical composition for nasal delivery
US7306812B2 (en) * 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
DE10325813B4 (de) * 2003-06-06 2007-12-20 Universitätsklinikum Freiburg Prophylaxe und/oder Therapie bei der portalen Hypertonie
AU2005239962B2 (en) * 2004-05-11 2011-07-07 Eb Ip Lybrido B.V. Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction
RS20070166A (en) * 2004-10-20 2008-09-29 Endorecherche Inc., Sex steroid precursors alone or in combination with a selective estrogen receptor modulator...
TR201815853T4 (tr) 2005-10-12 2018-11-21 Besins Healthcare Sarl Hipogonadizmin tedavisinde kullanıma yönelik geliştirilmiş testosteron jeli.
KR20090121315A (ko) * 2007-02-12 2009-11-25 디엠아이 바이오사이언시스 인코포레이티드 조루 및 발기부전을 동시에 치료하는 방법
DK2114147T3 (da) * 2007-02-12 2012-06-25 Dmi Biosciences Inc Reduktion af bivirkninger af tramadol
US8741918B2 (en) 2007-06-21 2014-06-03 Veroscience Llc Parenteral formulations of dopamine agonists
US20100035886A1 (en) 2007-06-21 2010-02-11 Veroscience, Llc Parenteral formulations of dopamine agonists
GB0715285D0 (en) * 2007-08-06 2007-09-12 Britannia Pharmaceuticals Ltd Improvements in or relating to powdered medicaments for nasal delivery
US8268806B2 (en) 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
US9011864B2 (en) * 2007-12-26 2015-04-21 Biotest Ag Method of decreasing cytotoxic side-effects and improving efficacy of immunoconjugates
RU2486203C2 (ru) * 2007-12-26 2013-06-27 Биотест Аг Способы улучшения направленного воздействия на cd138-экспрессирующие опухолевые клетки и агенты для их осуществления
JP5990365B2 (ja) * 2007-12-26 2016-09-14 バイオテスト・アクチエンゲゼルシヤフト Ｃｄ１３８を標的とする剤及びその使用
WO2009080830A1 (en) * 2007-12-26 2009-07-02 Biotest Ag Immunoconjugates targeting cd138 and uses thereof
US20090246298A1 (en) * 2008-03-31 2009-10-01 Ceola P. Steele Viagra
US20100184722A1 (en) * 2008-12-19 2010-07-22 Shimoda Biotech (Pty) Ltd Inclusion complexes of alpha-cyclodextrin and sildenafil salt
CA2761120A1 (en) * 2009-05-06 2010-11-11 Biotest Ag Uses of immunoconjugates targeting cd138
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
DK2442650T3 (en) 2009-06-12 2015-12-07 Cynapsus Therapeutics Inc sublingual apomorphine
WO2012000634A1 (de) 2010-06-29 2012-01-05 Georg Bambach Pharmazeutische zusammensetzung zur behandlung von erektiler dysfunktion
TWI462739B (zh) 2010-11-02 2014-12-01 Univ Kaohsiung Medical Ｓｉｌｄｅｎａｆｉｌ－同族物四級銨哌嗪鹽類之製備及醫療用途
CA3115370A1 (en) 2010-12-16 2012-06-21 Sunovion Pharmaceuticals Inc. Sublingual films comprising apomorphine and an organic base
RU2632108C2 (ru) 2011-12-08 2017-10-02 Биотест Аг Применения иммуноконъюгатов, мишенью которых является cd138
CA3127926A1 (en) 2015-04-21 2016-10-27 Sunovion Pharmaceuticals Inc. Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256652A (en) * 1987-11-12 1993-10-26 Pharmedic Co. Topical compositions and methods for treatment of male impotence
DE69514794T2 (de) * 1994-04-22 2000-07-27 Pentech Pharmaceuticals, Inc. Sublinguale dosierungsformen enthaltend apomorphin zur verwendung bei der behandlung von erektiler dysfunktion
GB9612514D0 (en) * 1996-06-14 1996-08-14 Pfizer Ltd Novel process
BR9809848A (pt) * 1997-05-19 2000-06-27 Zonagen Inc Composição
US6037346A (en) * 1997-10-28 2000-03-14 Vivus, Inc. Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
US6200591B1 (en) * 1998-06-25 2001-03-13 Anwar A. Hussain Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction

Also Published As

Publication number Publication date
BR0009016A (pt) 2002-04-16
EP1173178A1 (en) 2002-01-23
ES2244418T3 (es) 2005-12-16
CA2367605A1 (en) 2000-09-21
CN1350454A (zh) 2002-05-22
JP2002539163A (ja) 2002-11-19
PT1173178E (pt) 2005-11-30
NZ514464A (en) 2004-01-30
HUP0200549A3 (en) 2004-07-28
MXPA01009332A (es) 2002-06-21
HUP0200549A2 (hu) 2002-07-29
NO324511B1 (no) 2007-11-05
WO2000054774A1 (en) 2000-09-21
PL350313A1 (en) 2002-12-02
ATE302003T1 (de) 2005-09-15
CZ20013344A3 (cs) 2002-08-14
US6087362A (en) 2000-07-11
NO20014519L (no) 2001-10-25
EP1173178A4 (en) 2002-09-04
DE60022021T2 (de) 2006-06-08
AU3744500A (en) 2000-10-04
DE60022021D1 (de) 2005-09-22
IL145487A0 (en) 2002-06-30
NO20014519D0 (no) 2001-09-17
EP1173178B1 (en) 2005-08-17
ZA200107920B (en) 2003-03-26

Similar Documents

Publication Publication Date Title
DK1173178T3 (da) Præparat, der omfatter apomorfin og sildenafil, og anvendelse deraf til behandling af erektil dysfunktion
NO20043871L (no) Legemiddelformuleringer med kontrollert frigjoring som inneholder et baererpeptid
EA200600820A1 (ru) Способы лечения, модификации и устранения боли с использованием 1-оксо-2-(2,6-диоксопиперидин-3-ил)-4-метилизоиндолина
NZ517038A (en) Use of serotonin reuptake inihibitor in medicaments for treating sexual dysfunction
BRPI0510862A (pt) medicamento para tratar disfunção sexual em um paciente, medicamento para tratar disfunção erétil em um paciente, medicamento para diminuir os efeitos colaterais associados com os agentes terapêuticos para tratar a disfunção sexual em um paciente, método para fabricação de um medicamento para tratamento da disfunção sexual de um paciente responsivo marginalmente ao inibidor de pde5, e uso do peptìdeo ac-nle-ciclo (-asp-his-d-phe-arg-trp-lys) -0h na perparação de um medicamento
WO2004039325A3 (en) Treatment of pain with jnk inhibitors
ATE405272T1 (de) Behandlung von t-zellen-lymphom mittels 10- propargyl-10-deazaaminopterin
AR023185A1 (es) Tratamiento de cancer mejorado con temozolomida
FI20011464A0 (fi) Yhdistelmäterapia sydämen vajaatoiminnan hoitoon
HK1077215A1 (en) A pharmaceutical composition for treatment of acute myocardial infarction
AR048318A1 (es) Formulaciones de matriz orales que comprenden licarbazepina
PT1251850E (pt) Utilizacao de uma preparacao de combinacao na terapia do cancro
AR029160A1 (es) El uso del interferon-alfa pegilado para la preparacion de un medicamento para el tratamiento del carcinoma de celula renal, un kit y el uso del mismo
AR047154A1 (es) Tratamiento del insomnio en pacientes humanos administrandoles una cantidad diaria de gaboxadol
AR109456A2 (es) Uso de et743 para la preparación de un medicamento para el tratamiento de un paciente humano afectado por cáncer mediante terapia de combinación
TH68160A (th) การรักษาการเสื่อมหน้าที่ทางเพศที่เกิดจากยาต้านอาการซึมเศร้าด้วยอะโพมอร์ฟีน
RU2002129097A (ru) Комбинированные терапии с использованием активности, повреждающей сосуды
DK1265629T3 (da) Anvendelse af væksthormon i lav dosis
EA200000514A1 (ru) Способ лечения эректильной дисфункции
BRPI0503488A (pt) agente de tratamento para sìndrome de intestino irritável com diarréia predominante