[go: up one dir, main page]

PT1146044E - Derivados de ciclobuta-indole-carboxamida que actuam sobre o sistema nervoso central processo para a sua preparacao e as composicoes farmaceuticas que os contem - Google Patents

Derivados de ciclobuta-indole-carboxamida que actuam sobre o sistema nervoso central processo para a sua preparacao e as composicoes farmaceuticas que os contem

Info

Publication number
PT1146044E
PT1146044E PT01400939T PT01400939T PT1146044E PT 1146044 E PT1146044 E PT 1146044E PT 01400939 T PT01400939 T PT 01400939T PT 01400939 T PT01400939 T PT 01400939T PT 1146044 E PT1146044 E PT 1146044E
Authority
PT
Portugal
Prior art keywords
cylobutan
indole
contain
preparation
pharmaceutical compositions
Prior art date
Application number
PT01400939T
Other languages
English (en)
Inventor
Jean-Louis Peglion
Mark Millan
Francoise Lejeune
Bertrand Goument
Didier Cussac
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of PT1146044E publication Critical patent/PT1146044E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT01400939T 2000-04-13 2001-04-12 Derivados de ciclobuta-indole-carboxamida que actuam sobre o sistema nervoso central processo para a sua preparacao e as composicoes farmaceuticas que os contem PT1146044E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0004743A FR2807754A1 (fr) 2000-04-13 2000-04-13 Nouveaux derives de cyclobuta-indole carboxamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PT1146044E true PT1146044E (pt) 2004-11-30

Family

ID=8849213

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01400939T PT1146044E (pt) 2000-04-13 2001-04-12 Derivados de ciclobuta-indole-carboxamida que actuam sobre o sistema nervoso central processo para a sua preparacao e as composicoes farmaceuticas que os contem

Country Status (24)

Country Link
US (2) US6452015B2 (pt)
EP (1) EP1146044B1 (pt)
JP (1) JP3396675B2 (pt)
KR (1) KR100470691B1 (pt)
CN (1) CN1323796A (pt)
AR (1) AR042379A1 (pt)
AT (1) ATE275140T1 (pt)
AU (1) AU779366B2 (pt)
BR (1) BR0101466A (pt)
CA (1) CA2344108C (pt)
DE (1) DE60105219T2 (pt)
DK (1) DK1146044T3 (pt)
EA (1) EA004738B1 (pt)
ES (1) ES2227082T3 (pt)
FR (1) FR2807754A1 (pt)
HK (1) HK1040247A1 (pt)
HU (1) HUP0101504A3 (pt)
NO (1) NO318206B1 (pt)
NZ (1) NZ511091A (pt)
PL (1) PL347046A1 (pt)
PT (1) PT1146044E (pt)
SI (1) SI1146044T1 (pt)
TR (1) TR200402685T4 (pt)
ZA (1) ZA200103064B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2837823B1 (fr) * 2002-03-27 2005-04-08 Servier Lab Nouveaux derives d'indoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2933975B1 (fr) * 2008-07-17 2011-02-18 Servier Lab Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable.
KR20220029900A (ko) * 2020-09-02 2022-03-10 에스케이하이닉스 주식회사 버퍼 회로

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ254785A (en) * 1992-08-20 1995-09-26 Smithkline Beecham Plc Heterocyclically-condensed indoles and medicaments
GB9306460D0 (en) * 1993-03-29 1993-05-19 Smithkline Beecham Plc Novel compounds
WO1995029177A1 (en) * 1994-04-23 1995-11-02 Smithkline Beecham P.L.C. Tricyclic derivatives as 5ht2c and 5ht2b antagonists
RO115522B1 (ro) * 1995-02-02 2000-03-30 Smithkline Beecham P.L.C. Derivaţi de indolină, procedee pentru prepararea acestora, compoziţii farmaceutice care îi conţin şi metodă de tratament
CA2195346C (en) * 1995-12-21 2007-04-10 Zhi Yuan Wang Benzocyclobutenones and polymers derived therefrom
CA2321900C (en) * 1998-02-27 2011-07-19 The Board Of Trustees Of The University Of Illinois Agents with serotonin-related activity for the treatment for sleep apnea

Also Published As

Publication number Publication date
FR2807754A1 (fr) 2001-10-19
BR0101466A (pt) 2001-12-11
JP2001302661A (ja) 2001-10-31
NO318206B1 (no) 2005-02-14
US6743818B2 (en) 2004-06-01
KR100470691B1 (ko) 2005-03-07
AU779366B2 (en) 2005-01-20
NO20011863L (no) 2001-10-15
HUP0101504A3 (en) 2002-11-28
SI1146044T1 (en) 2004-12-31
DE60105219T2 (de) 2005-09-15
ATE275140T1 (de) 2004-09-15
ES2227082T3 (es) 2005-04-01
EA200100344A3 (ru) 2002-02-28
US6452015B2 (en) 2002-09-17
CN1323796A (zh) 2001-11-28
EP1146044B1 (fr) 2004-09-01
PL347046A1 (en) 2001-10-22
HUP0101504A2 (hu) 2002-02-28
JP3396675B2 (ja) 2003-04-14
NO20011863D0 (no) 2001-04-11
AR042379A1 (es) 2005-06-22
US20010044426A1 (en) 2001-11-22
AU3518601A (en) 2001-10-18
CA2344108A1 (fr) 2001-10-13
EA200100344A2 (ru) 2001-10-22
EA004738B1 (ru) 2004-08-26
US20030032812A1 (en) 2003-02-13
HK1040247A1 (zh) 2002-05-31
NZ511091A (en) 2001-09-28
CA2344108C (fr) 2005-11-29
DE60105219D1 (de) 2004-10-07
ZA200103064B (en) 2001-10-18
KR20010098581A (ko) 2001-11-08
DK1146044T3 (da) 2004-12-27
EP1146044A1 (fr) 2001-10-17
HU0101504D0 (en) 2001-06-28
TR200402685T4 (tr) 2004-11-22

Similar Documents

Publication Publication Date Title
PT1339675E (pt) Compostos bisarilo orto, meta-substituidos, processo para a sua preparacao, sua utilizacao como medicamentos e composicoes farmaceuticas que os contem
PT1150961E (pt) Derivados do acido pirazolecarboxilico processo para a sua preparacao e as composicoes farmaceuticas que os contem
PT1192122E (pt) Derivados de benzeno processo para a sua preparacao e composicoes farmaceuticas que os contem
BR0017030B1 (pt) derivados de tiazolilamida, processo para sua preparação, composição farmacêutica que os compreende e uso dos mesmos
BR0008840B1 (pt) derivados de camptotecina, processos para a sua preparaÇço, composiÇço farmacÊutica que os compreende e uso dos mesmos.
PT1152765E (pt) Etanolato de azitromicina, processo de preparacao e composicoes farmaceuticas que os contem
PT1194403E (pt) Benzenocarbonamidas substituidas com indanilo, processo para a sua preparacao, sua utilizacao como medicamento bem como preparacoes farmaceuticas que as contem
BR9910900B1 (pt) compostos derivados de isotiazol, processo para sua preparação e composição farmacêutica dos mesmos
BR0009083B1 (pt) derivado de amida compreendendo um núcleo de quinazolinona, processo para a preparação de um derivado de amida, composição farmacêutica, e, uso de um derivado de amida.
PT1202965E (pt) Derivados de indol processos para a sua preparacao composicoes farmaceuticas que os contem e a sua aplicacao
PT1036794E (pt) Derivados de 2-aril-8-oxodi-hidropurina processo para a sua producao composicoes medicinais que os contem e seus intermediarios
BR0009486B1 (pt) composto que compreende uma amida, composição farmacêutica que compreende esse composto, seu uso e processo para a preparação do mesmo.
PT99671A (pt) Processo para a preparacao de heparosanos-n,o-sulfatados e de composicoes farmaceuticas que os contem
PT1112266E (pt) 4-amino-2-aril-pirimidinas substituidas, sua preparacao, sua utilizacao e composicoes farmaceuticas que as contem.
PT1122254E (pt) Derivados de 4-sulfonamidas piperidina, processo para a sua preparacao e as composicoes farmaceuticas que os contem
BR0015939B1 (pt) Sistema terapêutico transdérmico com estabilidade aperfeiçoada e processo para a sua preparação
PT1118610E (pt) Novos derivados de benzeno-sulfonamida processo para a sua preparacao e as composicoes farmaceuticas que os contem
PT1187847E (pt) Derivados de estreptograminas sua preparacao e as composicoes que os contem
AR026072A1 (es) Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
BR9701085A (pt) Derivado de vitamina d cristalina processo para preparar o mesmo medicamento composição farmacéutica processo para preparar a mesma e uso do derivado
PT1049706E (pt) Novos penta-sacaridos os respectivos metodos de producao e as composicoes farmaceuticas que os contem
PT1224210E (pt) Compostos monociclicos basicos tendo accao antagonista de nk-2 processos para a sua preparacao e formulacoes que os contem
PT1275647E (pt) Derivados de octa-hidro-2h-pirido¬1,2-a|pirazina processo para a sua preparacao e as composicoes farmaceuticas que os contem
PT1245565E (pt) Derivados de indenoindolonas processo para a sua preparacao e as composicoes farmaceuticas que os contem
PT1395582E (pt) Novos derivados de piperidinocarboxamida, metodo para a sua preparacao e composicoes farmaceuticas que os contem