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BR0101466A - Compostos de ciclobutaindolcarboxamida,processo para a sua preparação e composiçõesfarmacêuticas contendo os mesmos - Google Patents

Compostos de ciclobutaindolcarboxamida,processo para a sua preparação e composiçõesfarmacêuticas contendo os mesmos

Info

Publication number
BR0101466A
BR0101466A BR0101466-8A BR0101466A BR0101466A BR 0101466 A BR0101466 A BR 0101466A BR 0101466 A BR0101466 A BR 0101466A BR 0101466 A BR0101466 A BR 0101466A
Authority
BR
Brazil
Prior art keywords
compounds
pharmaceutical compositions
compositions containing
same
hydrogen
Prior art date
Application number
BR0101466-8A
Other languages
English (en)
Inventor
Jean-Louis Peglion
Bertrand Goument
Mark Millan
Francoise Lejeune
Didier Cussac
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of BR0101466A publication Critical patent/BR0101466A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: "COMPOSTOS DECICLOBUTAINDOLCARBOXAMIDA, PROCESSO PARA A SUAPREPARAçãO E COMPOSIçõES FARMACêUTICASCONTENDO OS MESMOS". Compostos da fórmulas (I): onde: nrepresenta um número inteiro de O a 6; R~ 1~ representa um gruposelecionado de hidrogênio, hidróxi, ciano, alcóxi, alcoxicarbonila,carbóxi, aminocarbonila opcionalmente substituída e NR~ 4~R~5~ onde R~ 4~ e R~ 5~, são como definido no relatório R~ 2~representa um grupo selecionado de hidrogênio, alquila,hidroximetila, um grupo da fórmula onde T, U, V e W são conformedefinido no relatório e R~ 3~ representa um grupo selecionado dehidrogênio, (C~ 1~-C~ 6~) alquila linear ou ramificada, arila eheteroarila, seus isómeros, e também aos seus sais de adição comum ácido ou base farmaceuticamente aceitável.
BR0101466-8A 2000-04-13 2001-04-11 Compostos de ciclobutaindolcarboxamida,processo para a sua preparação e composiçõesfarmacêuticas contendo os mesmos BR0101466A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0004743A FR2807754A1 (fr) 2000-04-13 2000-04-13 Nouveaux derives de cyclobuta-indole carboxamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR0101466A true BR0101466A (pt) 2001-12-11

Family

ID=8849213

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0101466-8A BR0101466A (pt) 2000-04-13 2001-04-11 Compostos de ciclobutaindolcarboxamida,processo para a sua preparação e composiçõesfarmacêuticas contendo os mesmos

Country Status (24)

Country Link
US (2) US6452015B2 (pt)
EP (1) EP1146044B1 (pt)
JP (1) JP3396675B2 (pt)
KR (1) KR100470691B1 (pt)
CN (1) CN1323796A (pt)
AR (1) AR042379A1 (pt)
AT (1) ATE275140T1 (pt)
AU (1) AU779366B2 (pt)
BR (1) BR0101466A (pt)
CA (1) CA2344108C (pt)
DE (1) DE60105219T2 (pt)
DK (1) DK1146044T3 (pt)
EA (1) EA004738B1 (pt)
ES (1) ES2227082T3 (pt)
FR (1) FR2807754A1 (pt)
HK (1) HK1040247A1 (pt)
HU (1) HUP0101504A3 (pt)
NO (1) NO318206B1 (pt)
NZ (1) NZ511091A (pt)
PL (1) PL347046A1 (pt)
PT (1) PT1146044E (pt)
SI (1) SI1146044T1 (pt)
TR (1) TR200402685T4 (pt)
ZA (1) ZA200103064B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2837823B1 (fr) * 2002-03-27 2005-04-08 Servier Lab Nouveaux derives d'indoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2933975B1 (fr) * 2008-07-17 2011-02-18 Servier Lab Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable.
KR20220029900A (ko) * 2020-09-02 2022-03-10 에스케이하이닉스 주식회사 버퍼 회로

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ254785A (en) * 1992-08-20 1995-09-26 Smithkline Beecham Plc Heterocyclically-condensed indoles and medicaments
GB9306460D0 (en) * 1993-03-29 1993-05-19 Smithkline Beecham Plc Novel compounds
WO1995029177A1 (en) * 1994-04-23 1995-11-02 Smithkline Beecham P.L.C. Tricyclic derivatives as 5ht2c and 5ht2b antagonists
RO115522B1 (ro) * 1995-02-02 2000-03-30 Smithkline Beecham P.L.C. Derivaţi de indolină, procedee pentru prepararea acestora, compoziţii farmaceutice care îi conţin şi metodă de tratament
CA2195346C (en) * 1995-12-21 2007-04-10 Zhi Yuan Wang Benzocyclobutenones and polymers derived therefrom
CA2321900C (en) * 1998-02-27 2011-07-19 The Board Of Trustees Of The University Of Illinois Agents with serotonin-related activity for the treatment for sleep apnea

Also Published As

Publication number Publication date
FR2807754A1 (fr) 2001-10-19
JP2001302661A (ja) 2001-10-31
NO318206B1 (no) 2005-02-14
US6743818B2 (en) 2004-06-01
KR100470691B1 (ko) 2005-03-07
PT1146044E (pt) 2004-11-30
AU779366B2 (en) 2005-01-20
NO20011863L (no) 2001-10-15
HUP0101504A3 (en) 2002-11-28
SI1146044T1 (en) 2004-12-31
DE60105219T2 (de) 2005-09-15
ATE275140T1 (de) 2004-09-15
ES2227082T3 (es) 2005-04-01
EA200100344A3 (ru) 2002-02-28
US6452015B2 (en) 2002-09-17
CN1323796A (zh) 2001-11-28
EP1146044B1 (fr) 2004-09-01
PL347046A1 (en) 2001-10-22
HUP0101504A2 (hu) 2002-02-28
JP3396675B2 (ja) 2003-04-14
NO20011863D0 (no) 2001-04-11
AR042379A1 (es) 2005-06-22
US20010044426A1 (en) 2001-11-22
AU3518601A (en) 2001-10-18
CA2344108A1 (fr) 2001-10-13
EA200100344A2 (ru) 2001-10-22
EA004738B1 (ru) 2004-08-26
US20030032812A1 (en) 2003-02-13
HK1040247A1 (zh) 2002-05-31
NZ511091A (en) 2001-09-28
CA2344108C (fr) 2005-11-29
DE60105219D1 (de) 2004-10-07
ZA200103064B (en) 2001-10-18
KR20010098581A (ko) 2001-11-08
DK1146044T3 (da) 2004-12-27
EP1146044A1 (fr) 2001-10-17
HU0101504D0 (en) 2001-06-28
TR200402685T4 (tr) 2004-11-22

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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