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PT1095040E - Novos benzoxazoles com actividade inibidora da pde - Google Patents

Novos benzoxazoles com actividade inibidora da pde

Info

Publication number
PT1095040E
PT1095040E PT99931198T PT99931198T PT1095040E PT 1095040 E PT1095040 E PT 1095040E PT 99931198 T PT99931198 T PT 99931198T PT 99931198 T PT99931198 T PT 99931198T PT 1095040 E PT1095040 E PT 1095040E
Authority
PT
Portugal
Prior art keywords
inhibiting activity
pde
benzoxazoles
new
pde inhibiting
Prior art date
Application number
PT99931198T
Other languages
English (en)
Inventor
Dietrich Hafner
Hans-Peter Kley
Thomas Bar
Thomas Martin
Wolf-Rudiger Ulrich
Hildegard Boss
Dieter Flockerzi
Beate Schmidt
Armin Hatzelmann
Hermann Amschler
Ulrich Thibaut
Rolf Beume
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT1095040E publication Critical patent/PT1095040E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT99931198T 1998-07-06 1999-06-26 Novos benzoxazoles com actividade inibidora da pde PT1095040E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98112469 1998-07-06

Publications (1)

Publication Number Publication Date
PT1095040E true PT1095040E (pt) 2004-08-31

Family

ID=8232222

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99931198T PT1095040E (pt) 1998-07-06 1999-06-26 Novos benzoxazoles com actividade inibidora da pde

Country Status (14)

Country Link
US (1) US6376485B1 (pt)
EP (1) EP1095040B1 (pt)
JP (1) JP2002519423A (pt)
AT (1) ATE263166T1 (pt)
AU (1) AU761647B2 (pt)
CA (1) CA2336894A1 (pt)
DE (1) DE69916066T2 (pt)
DK (1) DK1095040T3 (pt)
ES (1) ES2219031T3 (pt)
IL (1) IL140468A0 (pt)
PT (1) PT1095040E (pt)
SI (1) SI1095040T1 (pt)
WO (1) WO2000001695A1 (pt)
ZA (1) ZA200100088B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83620C2 (ru) 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
CA2625153A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス，インコーポレイティド 神経発生のｇａｂａ受容体媒介調節
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
KR20100097711A (ko) * 2007-11-21 2010-09-03 디코드 제네틱스 이에이치에프 폐 및 심혈관 질환의 치료를 위한 치환된 벤조아졸 ｐｄｅ4 억제제
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405633A (en) * 1982-03-01 1983-09-20 Usv Pharmaceutical Corporation Method of treatment of asthma
US4490373A (en) * 1983-05-20 1984-12-25 Usv Pharmaceutical Corporation Method of treating asthma
ATE248153T1 (de) * 1994-10-12 2003-09-15 Euro Celtique Sa Neue benzoxazole
ATE230404T1 (de) * 1995-05-18 2003-01-15 Altana Pharma Ag Cyclohexyldihydrobenzofurane
DK0771794T3 (da) * 1995-05-19 2006-09-11 Kyowa Hakko Kogyo Kk Oxygenholdige heterocykliske forbindelser

Also Published As

Publication number Publication date
CA2336894A1 (en) 2000-01-13
ES2219031T3 (es) 2004-11-16
DE69916066T2 (de) 2005-02-24
SI1095040T1 (en) 2004-10-31
EP1095040A1 (en) 2001-05-02
DK1095040T3 (da) 2004-07-26
US6376485B1 (en) 2002-04-23
EP1095040B1 (en) 2004-03-31
AU761647B2 (en) 2003-06-05
ZA200100088B (en) 2002-05-06
WO2000001695A1 (en) 2000-01-13
ATE263166T1 (de) 2004-04-15
JP2002519423A (ja) 2002-07-02
IL140468A0 (en) 2002-02-10
AU4778699A (en) 2000-01-24
DE69916066D1 (de) 2004-05-06

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