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PL443857A1 - 3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone - Google Patents

3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone

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Publication number
PL443857A1
PL443857A1 PL443857A PL44385723A PL443857A1 PL 443857 A1 PL443857 A1 PL 443857A1 PL 443857 A PL443857 A PL 443857A PL 44385723 A PL44385723 A PL 44385723A PL 443857 A1 PL443857 A1 PL 443857A1
Authority
PL
Poland
Prior art keywords
chloro
methylglucopyranosyl
dihydrochalcone
formula
producing
Prior art date
Application number
PL443857A
Other languages
Polish (pl)
Inventor
Agnieszka Krawczyk-Łebek
Edyta Kostrzewa-Susłow
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL443857A priority Critical patent/PL443857A1/en
Publication of PL443857A1 publication Critical patent/PL443857A1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Przedmiotem zgłoszenia jest 3-Chloro-2'-O-β-D-(4"-O-metyloglukopiranozylo)-dihydrochalkon o wzorze 2 oraz sposób wytwarzania 3-chloro-2'-O-β-D-(4"-O-metyloglukopiranozylo)-dihydrochalkonu charakteryzujący się tym, że do podłoża odpowiedniego dla grzybów strzępkowych wprowadza się szczep Beauveria bassiana KCH J1.5, następnie po upływie co najmniej 72 godzin do hodowli wprowadza się substrat, którym jest 3-chloro-2'-hydroksychalkon o wzorze 1, rozpuszczony w rozpuszczalniku organicznym mieszającym się z wodą, transformację prowadzi się w temperaturze od 20 do 30 stopni Celsjusza, przy ciągłym wstrząsaniu, co najmniej 96 godzin, po czym produkt ekstrahuje się rozpuszczalnikiem organicznym niemieszającym się z wodą i oczyszcza chromatograficznie, przy czym 3-chloro-2'-O-β-D-(4"-O-metyloglukopiranozylo)-dihydrochalkon o wzorze 2 znajduje się we frakcji o pośredniej polarności, w trzecim paśmie od linii startu.The subject of the application is 3-Chloro-2'-O-β-D-(4"-O-methylglucopyranosyl)-dihydrochalcone of formula 2 and a method for producing 3-chloro-2'-O-β-D-(4"-O-methylglucopyranosyl)-dihydrochalcone characterized in that the Beauveria bassiana KCH J1.5 strain is introduced into a medium suitable for filamentous fungi, then after at least 72 hours a substrate is introduced into the culture, which is 3-chloro-2'-hydroxychalcone of formula 1, dissolved in an organic solvent miscible with water, the transformation is carried out at a temperature of 20 to 30 degrees Celsius, with continuous shaking, for at least 96 hours, after which the product is extracted with an organic solvent immiscible with water and purified chromatographically, wherein 3-chloro-2'-O-β-D-(4"-O-methylglucopyranosyl)-dihydrochalcone of formula 2 is located in the fraction of intermediate polarity, in the third band from the starting line.

PL443857A 2023-02-22 2023-02-22 3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone PL443857A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL443857A PL443857A1 (en) 2023-02-22 2023-02-22 3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL443857A PL443857A1 (en) 2023-02-22 2023-02-22 3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone

Publications (1)

Publication Number Publication Date
PL443857A1 true PL443857A1 (en) 2024-08-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL443857A PL443857A1 (en) 2023-02-22 2023-02-22 3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone

Country Status (1)

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PL (1) PL443857A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL438351A1 (en) * 2021-07-05 2023-01-09 Uniwersytet Przyrodniczy we Wrocławiu 2'-Hydroxy-2-methyl-3'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for the preparation of 2'-hydroxy-2-methyl-3'-O-β-D- (4''-O-methylglucopyranosyl)-dihydrochalcone
PL438645A1 (en) * 2021-07-30 2023-02-06 Uniwersytet Przyrodniczy we Wrocławiu 3-Hydroxy-2-methyl-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for the preparation of 3-hydroxy-2-methyl-2'-O-β-D-(4 ''O-methylglucopyranosyl)-dihydrochalcone

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL438351A1 (en) * 2021-07-05 2023-01-09 Uniwersytet Przyrodniczy we Wrocławiu 2'-Hydroxy-2-methyl-3'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for the preparation of 2'-hydroxy-2-methyl-3'-O-β-D- (4''-O-methylglucopyranosyl)-dihydrochalcone
PL438645A1 (en) * 2021-07-30 2023-02-06 Uniwersytet Przyrodniczy we Wrocławiu 3-Hydroxy-2-methyl-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for the preparation of 3-hydroxy-2-methyl-2'-O-β-D-(4 ''O-methylglucopyranosyl)-dihydrochalcone

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