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PL383422A1 - Analogi 12-aryloprostaglandyny - Google Patents

Analogi 12-aryloprostaglandyny

Info

Publication number
PL383422A1
PL383422A1 PL383422A PL38342205A PL383422A1 PL 383422 A1 PL383422 A1 PL 383422A1 PL 383422 A PL383422 A PL 383422A PL 38342205 A PL38342205 A PL 38342205A PL 383422 A1 PL383422 A1 PL 383422A1
Authority
PL
Poland
Prior art keywords
prostaglandin analogs
aryl
aryl prostaglandin
analogs
prostaglandin
Prior art date
Application number
PL383422A
Other languages
English (en)
Other versions
PL216197B1 (pl
Inventor
Yariv Donde
Jeremiah H. Nguyen
Original Assignee
Allergan, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan, Inc. filed Critical Allergan, Inc.
Publication of PL383422A1 publication Critical patent/PL383422A1/pl
Publication of PL216197B1 publication Critical patent/PL216197B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PL383422A 2004-12-10 2005-12-08 Analog 12-aryloprostaglandyny, jego zastosowanie w medycynie i zawierająca go okulistycznie dopuszczalna kompozycja ciekła PL216197B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/009,298 US7091231B2 (en) 2004-12-10 2004-12-10 12-Aryl prostaglandin analogs

Publications (2)

Publication Number Publication Date
PL383422A1 true PL383422A1 (pl) 2008-03-17
PL216197B1 PL216197B1 (pl) 2014-03-31

Family

ID=36578246

Family Applications (1)

Application Number Title Priority Date Filing Date
PL383422A PL216197B1 (pl) 2004-12-10 2005-12-08 Analog 12-aryloprostaglandyny, jego zastosowanie w medycynie i zawierająca go okulistycznie dopuszczalna kompozycja ciekła

Country Status (21)

Country Link
US (3) US7091231B2 (pl)
EP (1) EP1819670B1 (pl)
JP (1) JP5342142B2 (pl)
KR (1) KR101367553B1 (pl)
CN (1) CN101107225B (pl)
AR (1) AR052264A1 (pl)
AU (1) AU2005314000B2 (pl)
BR (1) BRPI0518642A2 (pl)
CA (1) CA2589864C (pl)
DK (1) DK1819670T3 (pl)
ES (1) ES2394838T3 (pl)
HK (1) HK1114832A1 (pl)
IL (1) IL183360A (pl)
MX (1) MX2007006690A (pl)
NO (1) NO20072662L (pl)
NZ (1) NZ555352A (pl)
PL (1) PL216197B1 (pl)
RU (1) RU2439055C2 (pl)
TW (1) TWI392666B (pl)
WO (1) WO2006063179A1 (pl)
ZA (1) ZA200704087B (pl)

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US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US8673341B2 (en) 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US7674786B2 (en) * 2005-05-06 2010-03-09 Allergan, Inc. Therapeutic β-lactams
US8039507B2 (en) * 2005-06-29 2011-10-18 Allergan, Inc. Therapeutic substituted gamma lactams
US7427685B2 (en) * 2005-12-06 2008-09-23 Allergan, Inc. Therapeutic substituted cyclopentanes
US7585895B2 (en) * 2005-12-06 2009-09-08 Allergan, Inc. Therapeutic substituted cyclopentanes
US7592364B2 (en) * 2006-02-28 2009-09-22 Allergan, Inc. Substituted gamma lactams as therapeutic agents
JP5052596B2 (ja) 2006-03-29 2012-10-17 ディグニティー ヘルス 患者の心周期による迷走神経刺激の同期化
US20090016981A1 (en) * 2006-05-03 2009-01-15 Allergan, Inc. Therapeutic compounds
US7476755B2 (en) * 2006-05-04 2009-01-13 Allergan, Inc. Therapeutic compounds
US7491844B2 (en) * 2006-05-04 2009-02-17 Allergan, Inc. Therapeutic cyclopentane derivatives
US7547727B2 (en) * 2006-05-22 2009-06-16 Allergan, Inc. Therapeutic cyclopentane derivatives
US7795287B2 (en) * 2006-09-01 2010-09-14 Allergan, Inc. Therapeutic substituted hydantoins and related compounds
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WO2008091810A1 (en) * 2007-01-22 2008-07-31 Allergan, Inc. Substituted arylcylopentenes as therapeutic agents
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US8377984B2 (en) * 2008-01-29 2013-02-19 Allergan, Inc. Substituted gamma lactams as therapeutic agents
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US7956051B2 (en) * 2008-01-24 2011-06-07 Allergan, Inc. Therapeutic amides and related compounds
US8455547B2 (en) 2008-02-05 2013-06-04 Allergan, Inc. Substituted cyclopentanes having prostaglandin activity
US8633310B2 (en) * 2008-02-19 2014-01-21 Allergan, Inc. Therapeutic substituted lactams
US8440819B2 (en) * 2008-02-22 2013-05-14 Allergan, Inc. Therapeutic substituted beta-lactams
US8487091B2 (en) * 2008-03-04 2013-07-16 Allergan, Inc. Substituted cyclopentanes having prostaglandin activity
US7964596B2 (en) 2008-03-07 2011-06-21 Allergan, Inc. Therapeutic compounds
US20090233921A1 (en) * 2008-03-11 2009-09-17 Allergan, Inc. Therapeutic cyclopentane derivatives
US7960379B2 (en) * 2008-03-14 2011-06-14 Allergan, Inc. Therapeutic compounds
US8198318B2 (en) * 2008-03-18 2012-06-12 Allergen, Inc. Therapeutic amides
US7705001B2 (en) * 2008-03-18 2010-04-27 Allergan, Inc Therapeutic substituted gamma lactams
US7732443B2 (en) * 2008-03-18 2010-06-08 Yariv Donde Therapeutic substituted cyclopentanes
US7956055B2 (en) * 2008-03-25 2011-06-07 Allergan, Inc. Substituted gamma lactams as therapeutic agents
WO2009129187A2 (en) * 2008-04-16 2009-10-22 Allergan, Inc. Combination therapy for glaucoma
US7964634B2 (en) * 2008-04-24 2011-06-21 Allergan, Inc. Therapeutic compounds
CA2722403C (en) * 2008-04-24 2017-03-07 Allergan, Inc. Substituted arylcyclopentenes as therapeutic agents
CN102076681A (zh) * 2008-04-24 2011-05-25 阿勒根公司 作为治疗剂的取代γ-内酰胺
US8263593B2 (en) 2008-04-24 2012-09-11 Allergan, Inc. Therapeutic compounds
CA2722456A1 (en) * 2008-04-24 2009-10-29 Allergan, Inc. Substituted arylcyclopentenes as prostaglandin ep2 agonists
AU2009239371B2 (en) * 2008-04-24 2014-05-01 Allergan, Inc. Thiophene derivatives useful as ocular hypotensive agents
WO2009137411A1 (en) * 2008-05-09 2009-11-12 Allergan, Inc. Therapeutic compounds
CA2728227A1 (en) * 2008-05-09 2009-11-12 Allergan, Inc. Therapeutic cyclopentane derivatives
US7964599B2 (en) 2008-05-09 2011-06-21 Allergan, Inc. Therapeutic compounds
WO2009137412A1 (en) * 2008-05-09 2009-11-12 Allergan, Inc. Therapeutic compounds
CA2723894A1 (en) 2008-05-09 2009-11-12 Allergan, Inc. Therapeutic substituted hydantoins, and related compounds
KR20110028584A (ko) * 2008-05-09 2011-03-21 알러간, 인코포레이티드 치료학적인 n-아릴 또는 n-헤테로아릴 피라졸리딘 및 피라졸리딘온 유도체
WO2009146255A1 (en) * 2008-05-27 2009-12-03 Allergan, Inc. Prostaglandin produgs as hypotensive agents
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US8952051B2 (en) * 2009-11-05 2015-02-10 Allergan, Inc. Ophthalmic formulations containing substituted gamma lactams and methods for use thereof
US9090584B2 (en) * 2010-01-26 2015-07-28 Allergan, Inc. Therapeutic agents for treatment of ocular hypertension
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JP6270848B2 (ja) * 2012-08-27 2018-01-31 アラーガン、インコーポレイテッドAllergan,Incorporated ベータ−クロロシクロペンタンの親水性エステルプロドラッグの使用による角膜中央部肥厚の低下
US9000032B2 (en) 2013-05-31 2015-04-07 Allergan, Inc. Substituted cyclopentenes as therapeutic agents
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Also Published As

Publication number Publication date
WO2006063179A1 (en) 2006-06-15
AU2005314000A1 (en) 2006-06-15
US8044092B2 (en) 2011-10-25
CN101107225B (zh) 2012-11-28
DK1819670T3 (da) 2012-09-17
CA2589864C (en) 2015-02-03
TW200633966A (en) 2006-10-01
NZ555352A (en) 2011-01-28
IL183360A0 (en) 2007-09-20
RU2007120520A (ru) 2009-01-20
KR101367553B1 (ko) 2014-03-14
KR20070086001A (ko) 2007-08-27
CN101107225A (zh) 2008-01-16
TWI392666B (zh) 2013-04-11
US7799821B2 (en) 2010-09-21
BRPI0518642A2 (pt) 2008-12-02
US20060205800A1 (en) 2006-09-14
PL216197B1 (pl) 2014-03-31
HK1114832A1 (en) 2008-11-14
RU2439055C2 (ru) 2012-01-10
AR052264A1 (es) 2007-03-07
AU2005314000B2 (en) 2012-06-14
MX2007006690A (es) 2007-08-14
EP1819670A1 (en) 2007-08-22
JP2008523088A (ja) 2008-07-03
JP5342142B2 (ja) 2013-11-13
IL183360A (en) 2010-12-30
NO20072662L (no) 2007-09-04
ZA200704087B (en) 2008-09-25
CA2589864A1 (en) 2006-06-15
ES2394838T3 (es) 2013-02-06
US7091231B2 (en) 2006-08-15
EP1819670B1 (en) 2012-08-08
US20060148894A1 (en) 2006-07-06
US20100317872A1 (en) 2010-12-16

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