PL2958903T3 - Sposób wytwarzania wortioksetyny - Google Patents

Sposób wytwarzania wortioksetyny

Info

Publication number: PL2958903T3
Authority: PL; Poland
Prior art keywords: vortioxetine; manufacturing process; manufacturing; vortioxetine manufacturing
Prior art date: 2013-02-22

Application number

PL14705524T

Other languages

English (en)

Inventor

Thomas Ruhland

Kim Lasse Christensen

Original Assignee

H. Lundbeck A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-02-22

Filing date

2014-02-20

Publication date

2017-08-31

2014-02-20 Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S

2017-08-31 Publication of PL2958903T3 publication Critical patent/PL2958903T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Compounds Of Unknown Constitution (AREA)
Saccharide Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

PL14705524T 2013-02-22 2014-02-20 Sposób wytwarzania wortioksetyny PL2958903T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201361767883P	2013-02-22	2013-02-22
DKPA201300104		2013-02-22
EP14705524.8A EP2958903B1 (en)	2013-02-22	2014-02-20	Vortioxetine manufacturing process

Publications (1)

Publication Number	Publication Date
PL2958903T3 true PL2958903T3 (pl)	2017-08-31

Family

ID=59215387

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL14705524T PL2958903T3 (pl)	2013-02-22	2014-02-20	Sposób wytwarzania wortioksetyny

Country Status (38)

Country	Link
US (1)	US9353073B2 (pl)
EP (1)	EP2958903B1 (pl)
JP (1)	JP6464098B2 (pl)
KR (1)	KR102230628B1 (pl)
CN (1)	CN104995181B (pl)
AP (1)	AP2015008640A0 (pl)
AU (1)	AU2014220735B2 (pl)
BR (1)	BR112015019268B1 (pl)
CA (1)	CA2901821A1 (pl)
CL (1)	CL2015002309A1 (pl)
CR (1)	CR20150423A (pl)
CY (1)	CY1118883T1 (pl)
DK (1)	DK2958903T3 (pl)
DO (1)	DOP2015000187A (pl)
EA (1)	EA027756B1 (pl)
ES (1)	ES2625380T3 (pl)
GE (1)	GEP201706749B (pl)
HK (1)	HK1216098A1 (pl)
HR (1)	HRP20170607T1 (pl)
IL (1)	IL240501B (pl)
LT (1)	LT2958903T (pl)
MA (1)	MA38338B1 (pl)
ME (1)	ME02671B (pl)
MX (1)	MX362355B (pl)
MY (1)	MY172337A (pl)
PE (1)	PE20151589A1 (pl)
PH (1)	PH12015501807B1 (pl)
PL (1)	PL2958903T3 (pl)
PT (1)	PT2958903T (pl)
RS (1)	RS55932B1 (pl)
RU (1)	RU2652265C2 (pl)
SG (1)	SG11201506651SA (pl)
SI (1)	SI2958903T1 (pl)
SM (1)	SMT201700238T1 (pl)
TN (1)	TN2015000335A1 (pl)
UA (1)	UA116236C2 (pl)
WO (1)	WO2014128207A1 (pl)
ZA (1)	ZA201506050B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RS62051B1 (sr)	2010-08-18	2021-07-30	Biosplice Therapeutics Inc	Diketoni i hidroksiketoni kao aktivatori katenin signalnog puta
US9533976B2 (en)	2013-02-22	2017-01-03	Samumed, Llc	γ-diketones as WNT/β-catenin signaling pathway activators
KR102165385B1 (ko)	2014-08-20	2020-10-15	사뮤메드, 엘엘씨	피부 노화 및 주름의 치료 및 예방을 위한 감마-디케톤
WO2016125191A2 (en)	2015-02-04	2016-08-11	Mylan Laboratories Limited	Processes for the preparation of vortioxetine hydrobromide
EP3274330A1 (en)	2015-03-26	2018-01-31	Cipla Limited	Method for making serotonin reuptake inhibitors
CN106279065A (zh) *	2015-05-12	2017-01-04	北京深蓝海生物医药科技有限公司	一种氢溴酸沃替西汀的精制转晶方法
JO3456B1 (ar)	2015-05-13	2020-07-05	H Lundbeck As	فيروتيوكسيتين بيروجلوتامات
EP3414216B1 (en) *	2016-02-08	2020-10-21	AAA Chemistry ApS	Arylation of aliphatic amines
BR112018003930A2 (pt)	2016-07-01	2018-09-25	H Lundbeck As	regimes de dosagem de vortioxetina para início rápido de efeito antidepressivo
US10519121B2 (en)	2016-12-30	2019-12-31	Apicore Us Llc	Process and novel polymorphic form of vortioxetine and its pharmaceutically acceptable salts
CN109912538B (zh) *	2019-01-22	2021-03-12	安徽赛乐普制药有限公司	一种抗抑郁药沃替西汀的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA81749C2 (uk) *	2001-10-04	2008-02-11	Х. Луннбек А/С	Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
CA2467118A1 (en) *	2001-12-20	2003-07-03	H. Lundbeck A/S	Aryloxyphenyl and arylsulfanylphenyl derivatives
RS52205B2 (sr) *	2006-06-16	2021-05-31	H Lundbeck A/S	1-[2-(2,4-dimetilfenilsulfanil)-fenil]piperazin kao jedinjenje sa kombinovanom aktivnošću ponovnog uzimanja serotonina, 5-ht3 i 5-ht1a, za tretman kognitivnih oštećenja
TW201033181A (en) *	2009-02-17	2010-09-16	Lundbeck & Co As H	Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine

2014
- 2014-02-20 ME MEP-2017-91A patent/ME02671B/me unknown
- 2014-02-20 MY MYPI2015002072A patent/MY172337A/en unknown
- 2014-02-20 MA MA38338A patent/MA38338B1/fr unknown
- 2014-02-20 CA CA2901821A patent/CA2901821A1/en not_active Abandoned
- 2014-02-20 WO PCT/EP2014/053313 patent/WO2014128207A1/en active Application Filing
- 2014-02-20 SM SM20170238T patent/SMT201700238T1/it unknown
- 2014-02-20 CN CN201480009227.0A patent/CN104995181B/zh active Active
- 2014-02-20 RS RS20170399A patent/RS55932B1/sr unknown
- 2014-02-20 ES ES14705524.8T patent/ES2625380T3/es active Active
- 2014-02-20 MX MX2015010656A patent/MX362355B/es active IP Right Grant
- 2014-02-20 PE PE2015001720A patent/PE20151589A1/es active IP Right Grant
- 2014-02-20 RU RU2015134407A patent/RU2652265C2/ru active
- 2014-02-20 EP EP14705524.8A patent/EP2958903B1/en active Active
- 2014-02-20 JP JP2015558446A patent/JP6464098B2/ja active Active
- 2014-02-20 LT LTEP14705524.8T patent/LT2958903T/lt unknown
- 2014-02-20 EA EA201591349A patent/EA027756B1/ru not_active IP Right Cessation
- 2014-02-20 UA UAA201509642A patent/UA116236C2/uk unknown
- 2014-02-20 PL PL14705524T patent/PL2958903T3/pl unknown
- 2014-02-20 PT PT147055248T patent/PT2958903T/pt unknown
- 2014-02-20 AU AU2014220735A patent/AU2014220735B2/en active Active
- 2014-02-20 KR KR1020157021985A patent/KR102230628B1/ko active Active
- 2014-02-20 US US14/767,350 patent/US9353073B2/en active Active
- 2014-02-20 GE GEAP201413919A patent/GEP201706749B/en unknown
- 2014-02-20 AP AP2015008640A patent/AP2015008640A0/xx unknown
- 2014-02-20 SG SG11201506651SA patent/SG11201506651SA/en unknown
- 2014-02-20 DK DK14705524.8T patent/DK2958903T3/en active
- 2014-02-20 BR BR112015019268-8A patent/BR112015019268B1/pt active IP Right Grant
- 2014-02-20 SI SI201430214T patent/SI2958903T1/sl unknown
2015
- 2015-08-06 TN TN2015000335A patent/TN2015000335A1/en unknown
- 2015-08-10 DO DO2015000187A patent/DOP2015000187A/es unknown
- 2015-08-11 IL IL240501A patent/IL240501B/en active IP Right Grant
- 2015-08-17 PH PH12015501807A patent/PH12015501807B1/en unknown
- 2015-08-18 CL CL2015002309A patent/CL2015002309A1/es unknown
- 2015-08-18 CR CR20150423A patent/CR20150423A/es unknown
- 2015-08-20 ZA ZA2015/06050A patent/ZA201506050B/en unknown
2016
- 2016-04-08 HK HK16104011.9A patent/HK1216098A1/zh unknown
2017
- 2017-04-18 HR HRP20170607TT patent/HRP20170607T1/hr unknown
- 2017-05-03 CY CY20171100483T patent/CY1118883T1/el unknown

Also Published As

Publication number	Publication date
LT2958903T (lt)	2017-08-25
EA201591349A1 (ru)	2015-12-30
SG11201506651SA (en)	2015-09-29
AU2014220735A1 (en)	2015-08-20
EP2958903A1 (en)	2015-12-30
DOP2015000187A (es)	2015-11-30
WO2014128207A1 (en)	2014-08-28
TN2015000335A1 (en)	2017-01-03
HRP20170607T1 (hr)	2017-06-30
CR20150423A (es)	2015-10-20
PT2958903T (pt)	2017-05-26
US20160009670A1 (en)	2016-01-14
JP2016509042A (ja)	2016-03-24
MY172337A (en)	2019-11-21
PH12015501807B1 (en)	2019-05-31
CL2015002309A1 (es)	2016-03-04
DK2958903T3 (en)	2017-05-15
PE20151589A1 (es)	2015-12-03
RU2652265C2 (ru)	2018-04-27
MX2015010656A (es)	2015-12-17
KR20150118146A (ko)	2015-10-21
UA116236C2 (uk)	2018-02-26
CA2901821A1 (en)	2014-08-28
MX362355B (es)	2019-01-14
GEP201706749B (en)	2017-10-10
AU2014220735B2 (en)	2017-06-22
AP2015008640A0 (en)	2015-08-31
KR102230628B1 (ko)	2021-03-22
SI2958903T1 (sl)	2017-09-29
BR112015019268B1 (pt)	2023-01-10
BR112015019268A2 (pt)	2020-01-28
IL240501B (en)	2018-08-30
CY1118883T1 (el)	2018-01-10
RU2015134407A (ru)	2017-03-28
ZA201506050B (en)	2017-08-30
EA027756B1 (ru)	2017-08-31
SMT201700238T1 (it)	2017-07-18
US9353073B2 (en)	2016-05-31
ME02671B (me)	2017-06-20
CN104995181B (zh)	2017-03-08
MA38338B1 (fr)	2018-10-31
PH12015501807A1 (en)	2015-11-09
RS55932B1 (sr)	2017-09-29
IL240501A0 (en)	2015-09-24
HK1216098A1 (zh)	2016-10-14
EP2958903B1 (en)	2017-04-12
MA38338A1 (fr)	2016-09-30
ES2625380T3 (es)	2017-07-19
CN104995181A (zh)	2015-10-21
JP6464098B2 (ja)	2019-02-06

Publication	Publication Date	Title
GB2520596B (en)	2018-08-15	Manufacturing method
GB201312991D0 (en)	2013-09-04	Process
HK1216098A1 (zh)	2016-10-14	沃替西汀生產方法
GB201321440D0 (en)	2014-01-22	Process
GB201307334D0 (en)	2013-05-29	Process
HK1220983A1 (zh)	2017-05-19	方法
GB201416005D0 (en)	2014-10-22	Process
GB201322454D0 (en)	2014-02-05	Process
GB201421426D0 (en)	2015-01-14	Process
GB201421428D0 (en)	2015-01-14	Process
GB201401963D0 (en)	2014-03-19	Process
GB201318888D0 (en)	2013-12-11	Process
GB201401922D0 (en)	2014-03-19	Process
GB201322273D0 (en)	2014-01-29	Process
GB201320869D0 (en)	2014-01-08	Process
GB201314334D0 (en)	2013-09-25	Process
GB201307327D0 (en)	2013-05-29	Process
GB201302441D0 (en)	2013-03-27	Process
GB201316253D0 (en)	2013-10-30	Process
GB201307951D0 (en)	2013-06-12	Process
GB201300073D0 (en)	2013-02-20	Process
GB201413623D0 (en)	2014-09-17	Process
GB201323151D0 (en)	2014-02-12	Process
GB201303604D0 (en)	2013-04-10	Manufacturing process
GB201418099D0 (en)	2014-11-26	Process