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PL1978015T3 - Związek prekursorowy związku organicznego znakowanego radioaktywnym halogenem - Google Patents

Związek prekursorowy związku organicznego znakowanego radioaktywnym halogenem

Info

Publication number
PL1978015T3
PL1978015T3 PL06833463T PL06833463T PL1978015T3 PL 1978015 T3 PL1978015 T3 PL 1978015T3 PL 06833463 T PL06833463 T PL 06833463T PL 06833463 T PL06833463 T PL 06833463T PL 1978015 T3 PL1978015 T3 PL 1978015T3
Authority
PL
Poland
Prior art keywords
compound
radioactive halogen
labeled organic
organic compound
halogen labeled
Prior art date
Application number
PL06833463T
Other languages
English (en)
Inventor
Osamu; Ito
Akio; Hayashi
Fumie; Kurosaki
Masahito; Toyama
Toshiyuki; Shinmura
Arinori; Harano
Original Assignee
Nihon Medi-Physics Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Medi-Physics Co., Ltd. filed Critical Nihon Medi-Physics Co., Ltd.
Publication of PL1978015T3 publication Critical patent/PL1978015T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0404Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL06833463T 2005-11-29 2006-11-28 Związek prekursorowy związku organicznego znakowanego radioaktywnym halogenem PL1978015T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005343653 2005-11-29
EP06833463.0A EP1978015B1 (en) 2005-11-29 2006-11-28 Precursor compound of radioactive halogen labeled organic compound
PCT/JP2006/323659 WO2007063824A1 (ja) 2005-11-29 2006-11-28 放射性ハロゲン標識有機化合物の前駆体化合物

Publications (1)

Publication Number Publication Date
PL1978015T3 true PL1978015T3 (pl) 2018-07-31

Family

ID=38092157

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06833463T PL1978015T3 (pl) 2005-11-29 2006-11-28 Związek prekursorowy związku organicznego znakowanego radioaktywnym halogenem

Country Status (17)

Country Link
US (7) US8758724B2 (pl)
EP (2) EP3354639B1 (pl)
JP (2) JP5635225B2 (pl)
KR (3) KR101643991B1 (pl)
CN (1) CN101316812A (pl)
AU (1) AU2006319987B2 (pl)
BR (1) BRPI0619213B8 (pl)
CA (1) CA2629227C (pl)
ES (1) ES2663496T3 (pl)
IL (2) IL191184A (pl)
NO (3) NO341981B1 (pl)
NZ (1) NZ568179A (pl)
PL (1) PL1978015T3 (pl)
PT (1) PT1978015T (pl)
RU (1) RU2428415C2 (pl)
TW (1) TW200800869A (pl)
WO (1) WO2007063824A1 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8758773B2 (en) 2005-12-09 2014-06-24 Wisconsin Alumni Research Foundation Vaccine candidates against Johne's disease
RU2466984C2 (ru) * 2006-12-27 2012-11-20 Нихон Меди-Физикс Ко., Лтд. Процесс получения соединений-предшественников для радиоактивных галогенпомеченных соединений
WO2012055992A2 (en) 2010-10-28 2012-05-03 Ge Healthcare Limited Stabilisation of radiopharmaceutical precursors
AU2011335084B2 (en) * 2010-11-29 2015-08-20 Ge Healthcare Limited Preparation of pet precursor
GB201021523D0 (en) 2010-12-20 2011-02-02 Ge Healthcare Ltd Process simplification for precursor compound
US9061977B2 (en) 2010-12-20 2015-06-23 Ge Healthcare Limited Purification of precursor compound by crystallisation
GB201021530D0 (en) * 2010-12-20 2011-02-02 Ge Healthcare Ltd Purification of precursor compound by crystallisation
WO2012120025A1 (en) 2011-03-08 2012-09-13 Ge Healthcare Limited Preparation of a 1-amino-3-hydroxy-cyclobutane-1-carboxylic acid derivative
ES2546997T3 (es) 2011-06-14 2015-09-30 Ge Healthcare Limited Preparación de un precursor para PET
ES2710564T3 (es) 2011-07-21 2019-04-25 Ge Healthcare Ltd Compuestos precursores y métodos para preparar los mismos
US11534494B2 (en) 2011-12-21 2022-12-27 Ge Healthcare Limited Formulation and method of synthesis
CA2853415C (en) * 2011-12-21 2020-11-17 Ge Healthcare Limited 18f - fluciclovine compositions in citrate buffers
GB201411569D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Novel formulation and method of synthesis
BR112017026003A2 (pt) * 2015-06-04 2018-08-14 Nihon Mediphysics Co Ltd ?agente de imagem de diagnóstico para metástase óssea precoce de câncer?
US10513367B2 (en) * 2016-02-12 2019-12-24 Graphic Packaging International, Llc Carton with handle
JP7165853B2 (ja) * 2017-03-07 2022-11-07 日本メジフィジックス株式会社 放射性フッ素標識前駆体化合物及びそれを用いた放射性フッ素標識化合物の製造方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360928A (en) * 1989-10-23 1994-11-01 Research Corporation Technologies, Inc. Synthesis and use of amino acid fluorides as peptide coupling reagents
JP3722294B2 (ja) 1993-02-23 2005-11-30 ワーナー−ランバート・コンパニー 実質的にアルコールを含有しない医薬組成物の製造方法
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
EP1077998B1 (en) * 1998-05-15 2008-01-16 GE Healthcare Limited Labelled glutamine and lysine analogues
PL360373A1 (pl) * 2000-08-08 2004-09-06 Ortho Mcneil Pharmaceutical, Inc. Bezimidazolowe aryloksypiperydyny
WO2002030943A1 (fr) 2000-10-12 2002-04-18 Chugai Seiyaku Kabushiki Kaisha Derive d'erythromycine possedant des nouvelles structures cristallines et procedes associes de production
EP1420831A1 (en) 2001-07-27 2004-05-26 Targesome, Inc. Lipid constructs as therapeutic and imaging agents
GB0229695D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
EP1660137A4 (en) 2003-07-31 2008-11-12 Univ St Louis SIGMA 2 RECEPTOR RADIOTRACER FOR IMAGING THE PROLIFERATION STATUS OF SOLID TUMORS
WO2005030677A1 (ja) * 2003-09-30 2005-04-07 Nihon Medi-Physics Co., Ltd. 放射性フッ素化合物の製造方法
CA2573109A1 (en) * 2004-06-17 2006-01-26 Thomas A. Dix Non-natural amino acids
JP4989467B2 (ja) * 2005-05-23 2012-08-01 日本メジフィジックス株式会社 新規有機化合物及び該化合物を利用した放射性ハロゲン標識有機化合物の製造方法
CA2612186A1 (en) * 2005-06-23 2007-01-04 Emory University Imaging agents
WO2007001958A2 (en) * 2005-06-23 2007-01-04 Emory University Stereoselective synthesis of amino acid analogs for tumor imaging
ES2380372T3 (es) 2006-05-11 2012-05-11 Nihon Medi-Physics Co., Ltd. Procedimiento para la producción de compuesto orgánico marcado con flúor radioactivo
EP2106808B1 (en) 2006-12-21 2018-02-21 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent comprising 1-amino-3-[18f]fluorocyclobutanecarboxylic acid
RU2466984C2 (ru) 2006-12-27 2012-11-20 Нихон Меди-Физикс Ко., Лтд. Процесс получения соединений-предшественников для радиоактивных галогенпомеченных соединений
EP2119458B9 (en) 2007-02-13 2013-08-21 Nihon Medi-Physics Co., Ltd. Method for production of radiation diagnostic imaging agent
JP5732198B2 (ja) 2007-12-19 2015-06-10 日本メジフィジックス株式会社 放射性フッ素標識有機化合物の製造方法

Also Published As

Publication number Publication date
US20160000944A1 (en) 2016-01-07
BRPI0619213B8 (pt) 2021-07-27
KR20130101158A (ko) 2013-09-12
NO2018027I1 (no) 2018-08-27
US10953112B2 (en) 2021-03-23
AU2006319987B2 (en) 2012-09-06
CN101316812A (zh) 2008-12-03
RU2428415C2 (ru) 2011-09-10
KR101643991B1 (ko) 2016-07-29
NZ568179A (en) 2010-06-25
EP1978015A1 (en) 2008-10-08
NO20180010A1 (no) 2008-08-25
US20080281121A1 (en) 2008-11-13
PT1978015T (pt) 2018-03-26
AU2006319987A1 (en) 2007-06-07
NO20082877L (no) 2008-08-25
CA2629227A1 (en) 2007-06-07
KR20080071146A (ko) 2008-08-01
US10010632B2 (en) 2018-07-03
US20180256760A1 (en) 2018-09-13
JP2013177468A (ja) 2013-09-09
IL235029A (en) 2016-02-29
US20160082135A1 (en) 2016-03-24
JPWO2007063824A1 (ja) 2009-05-07
EP1978015B1 (en) 2018-03-07
WO2007063824A1 (ja) 2007-06-07
KR20140108350A (ko) 2014-09-05
US9381259B2 (en) 2016-07-05
KR101608755B1 (ko) 2016-04-04
BRPI0619213A2 (pt) 2011-09-20
TWI371439B (pl) 2012-09-01
US20200282082A1 (en) 2020-09-10
NO2018027I2 (no) 2018-08-27
CA2629227C (en) 2014-02-25
US20210386873A1 (en) 2021-12-16
ES2663496T3 (es) 2018-04-13
IL191184A (en) 2015-07-30
EP3354639A1 (en) 2018-08-01
US20140213817A1 (en) 2014-07-31
TW200800869A (en) 2008-01-01
US11083804B2 (en) 2021-08-10
EP1978015A4 (en) 2010-08-11
JP5684333B2 (ja) 2015-03-11
BRPI0619213B1 (pt) 2018-12-26
JP5635225B2 (ja) 2014-12-03
NO341981B1 (no) 2018-03-05
RU2008126277A (ru) 2010-01-10
US9387266B2 (en) 2016-07-12
US8758724B2 (en) 2014-06-24
EP3354639B1 (en) 2024-02-21

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