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PT1978015T - Composto precursor de composto orgânico marcado com halogéneo radioativo - Google Patents

Composto precursor de composto orgânico marcado com halogéneo radioativo

Info

Publication number
PT1978015T
PT1978015T PT68334630T PT06833463T PT1978015T PT 1978015 T PT1978015 T PT 1978015T PT 68334630 T PT68334630 T PT 68334630T PT 06833463 T PT06833463 T PT 06833463T PT 1978015 T PT1978015 T PT 1978015T
Authority
PT
Portugal
Prior art keywords
compound
radioactive halogen
labeled organic
organic compound
halogen labeled
Prior art date
Application number
PT68334630T
Other languages
English (en)
Inventor
Ito Osamu
Hayashi Akio
Kurosaki Fumie
Toyama Masahito
Shinmura Toshiyuki
Harano Arinori
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of PT1978015T publication Critical patent/PT1978015T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0404Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT68334630T 2005-11-29 2006-11-28 Composto precursor de composto orgânico marcado com halogéneo radioativo PT1978015T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005343653 2005-11-29

Publications (1)

Publication Number Publication Date
PT1978015T true PT1978015T (pt) 2018-03-26

Family

ID=38092157

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68334630T PT1978015T (pt) 2005-11-29 2006-11-28 Composto precursor de composto orgânico marcado com halogéneo radioativo

Country Status (17)

Country Link
US (7) US8758724B2 (pt)
EP (2) EP1978015B1 (pt)
JP (2) JP5635225B2 (pt)
KR (3) KR101608755B1 (pt)
CN (1) CN101316812A (pt)
AU (1) AU2006319987B2 (pt)
BR (1) BRPI0619213B8 (pt)
CA (1) CA2629227C (pt)
ES (1) ES2663496T3 (pt)
IL (2) IL191184A (pt)
NO (3) NO341981B1 (pt)
NZ (1) NZ568179A (pt)
PL (1) PL1978015T3 (pt)
PT (1) PT1978015T (pt)
RU (1) RU2428415C2 (pt)
TW (1) TW200800869A (pt)
WO (1) WO2007063824A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8758773B2 (en) 2005-12-09 2014-06-24 Wisconsin Alumni Research Foundation Vaccine candidates against Johne's disease
CN101573330B (zh) 2006-12-27 2015-04-08 日本医事物理股份有限公司 放射性卤素标记的有机化合物的前体化合物的制备方法
CN103167884A (zh) * 2010-10-28 2013-06-19 通用电气健康护理有限公司 用干燥剂稳定放射性药物前体
JP6018578B2 (ja) 2010-11-29 2016-11-02 ジーイー・ヘルスケア・リミテッド Pet前駆体の製造
GB201021530D0 (en) * 2010-12-20 2011-02-02 Ge Healthcare Ltd Purification of precursor compound by crystallisation
US9061977B2 (en) 2010-12-20 2015-06-23 Ge Healthcare Limited Purification of precursor compound by crystallisation
GB201021523D0 (en) 2010-12-20 2011-02-02 Ge Healthcare Ltd Process simplification for precursor compound
DK2683684T3 (en) 2011-03-08 2018-02-05 Ge Healthcare Ltd PREPARATION OF A 1-AMINO-3-HYDROXY-CYCLOBUTANE-1-CARBOXYLIC ACID DERIVATIVE
ES2546997T3 (es) 2011-06-14 2015-09-30 Ge Healthcare Limited Preparación de un precursor para PET
EP2734494B1 (en) 2011-07-21 2019-01-02 GE Healthcare Limited Precursor compounds and methods for making same
ES2841109T3 (es) * 2011-12-21 2021-07-07 Ge Healthcare Ltd Composiciones de 18F-fluciclovina en tampones citrato
GB201411569D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Novel formulation and method of synthesis
US11534494B2 (en) 2011-12-21 2022-12-27 Ge Healthcare Limited Formulation and method of synthesis
US10857245B2 (en) * 2015-06-04 2020-12-08 Nihon Medi-Physics Co., Ltd. Diagnostic imaging agent for early bone metastasis from cancer
AU2017218125B2 (en) * 2016-02-12 2019-10-10 Graphic Packaging International, Llc Carton with handle
EP3594200B1 (en) * 2017-03-07 2022-03-02 Nihon Medi-Physics Co., Ltd. Radioactive fluorine-labeled precursor compound, and method for producing radioactive fluorine-labeled compound using same

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360928A (en) * 1989-10-23 1994-11-01 Research Corporation Technologies, Inc. Synthesis and use of amino acid fluorides as peptide coupling reagents
AU671536B2 (en) 1993-02-23 1996-08-29 Warner-Lambert Company A process for the preparation of substantially alcohol free pharmaceutical compositions
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
WO1999060018A1 (en) * 1998-05-15 1999-11-25 Nycomed Amersham Plc Labelled glutamine and lysine analogues
CN100396668C (zh) * 2000-08-08 2008-06-25 奥索-麦克尼尔药品公司 非-咪唑芳氧基哌啶
CA2425913C (en) 2000-10-12 2008-07-15 Chugai Seiyaku Kabushiki Kaisha Erythromycin derivative having novel crystal structures and processes for their production
EP1420831A1 (en) * 2001-07-27 2004-05-26 Targesome, Inc. Lipid constructs as therapeutic and imaging agents
GB0229695D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
US7390902B2 (en) 2003-07-31 2008-06-24 Washington University Sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors
WO2005030677A1 (ja) * 2003-09-30 2005-04-07 Nihon Medi-Physics Co., Ltd. 放射性フッ素化合物の製造方法
WO2006009902A2 (en) * 2004-06-17 2006-01-26 Musc Foundation For Research Development Non-natural amino acids
DK1889834T3 (da) * 2005-05-23 2011-08-08 Nihon Mediphysics Co Ltd Ny organisk forbindelse og fremgangsmåde til at fremstille radioaktiv halogenmærket organisk forbindelse ved anvendelse af samme
US7837982B2 (en) * 2005-06-23 2010-11-23 Emory University Imaging agents
US20060292073A1 (en) * 2005-06-23 2006-12-28 Emory University Stereoselective Synthesis of Amino Acid Analogs for Tumor Imaging
JP4550141B2 (ja) 2006-05-11 2010-09-22 日本メジフィジックス株式会社 放射性フッ素標識有機化合物の製造方法
KR101579796B1 (ko) 2006-12-21 2015-12-24 니혼 메디피직스 가부시키가이샤 방사성 화상 진단제
CN101573330B (zh) 2006-12-27 2015-04-08 日本医事物理股份有限公司 放射性卤素标记的有机化合物的前体化合物的制备方法
KR101485445B1 (ko) 2007-02-13 2015-01-22 니혼 메디피직스 가부시키가이샤 방사성 화상진단제의 제조 방법
EP2230229B1 (en) 2007-12-19 2016-10-12 Nihon Medi-Physics Co., Ltd. Process for production of radioactive-fluorine-labeled organic compound

Also Published As

Publication number Publication date
CN101316812A (zh) 2008-12-03
US20160000944A1 (en) 2016-01-07
RU2428415C2 (ru) 2011-09-10
US20180256760A1 (en) 2018-09-13
NO20082877L (no) 2008-08-25
US10010632B2 (en) 2018-07-03
IL235029A (en) 2016-02-29
US20080281121A1 (en) 2008-11-13
US9381259B2 (en) 2016-07-05
JP5684333B2 (ja) 2015-03-11
JP5635225B2 (ja) 2014-12-03
EP1978015A1 (en) 2008-10-08
EP3354639B1 (en) 2024-02-21
JP2013177468A (ja) 2013-09-09
BRPI0619213A2 (pt) 2011-09-20
US20140213817A1 (en) 2014-07-31
US9387266B2 (en) 2016-07-12
BRPI0619213B1 (pt) 2018-12-26
PL1978015T3 (pl) 2018-07-31
JPWO2007063824A1 (ja) 2009-05-07
AU2006319987B2 (en) 2012-09-06
NZ568179A (en) 2010-06-25
US11083804B2 (en) 2021-08-10
EP3354639A1 (en) 2018-08-01
US20160082135A1 (en) 2016-03-24
KR20080071146A (ko) 2008-08-01
NO341981B1 (no) 2018-03-05
NO2018027I1 (no) 2018-08-27
TW200800869A (en) 2008-01-01
US10953112B2 (en) 2021-03-23
KR20140108350A (ko) 2014-09-05
EP1978015A4 (en) 2010-08-11
KR20130101158A (ko) 2013-09-12
US20210386873A1 (en) 2021-12-16
RU2008126277A (ru) 2010-01-10
WO2007063824A1 (ja) 2007-06-07
US8758724B2 (en) 2014-06-24
KR101643991B1 (ko) 2016-07-29
NO2018027I2 (no) 2018-08-27
ES2663496T3 (es) 2018-04-13
NO20180010A1 (no) 2008-08-25
AU2006319987A1 (en) 2007-06-07
KR101608755B1 (ko) 2016-04-04
EP1978015B1 (en) 2018-03-07
TWI371439B (pt) 2012-09-01
BRPI0619213B8 (pt) 2021-07-27
CA2629227A1 (en) 2007-06-07
CA2629227C (en) 2014-02-25
IL191184A (en) 2015-07-30
US20200282082A1 (en) 2020-09-10

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