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PL1677846T3 - Kompozycje bioaktywnego hydrożelu do regenerowania tkanki łącznej - Google Patents

Kompozycje bioaktywnego hydrożelu do regenerowania tkanki łącznej

Info

Publication number
PL1677846T3
PL1677846T3 PL04796100T PL04796100T PL1677846T3 PL 1677846 T3 PL1677846 T3 PL 1677846T3 PL 04796100 T PL04796100 T PL 04796100T PL 04796100 T PL04796100 T PL 04796100T PL 1677846 T3 PL1677846 T3 PL 1677846T3
Authority
PL
Poland
Prior art keywords
connective tissue
hydrogel compositions
bioactive hydrogel
regenerating connective
regenerating
Prior art date
Application number
PL04796100T
Other languages
English (en)
Inventor
Ronald Stewart Hill
Richard Chris Klann
Francis V Lamberti
Original Assignee
Encelle Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Encelle Inc filed Critical Encelle Inc
Publication of PL1677846T3 publication Critical patent/PL1677846T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/10—Materials or treatment for tissue regeneration for reconstruction of tendons or ligaments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Composite Materials (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
PL04796100T 2003-10-22 2004-10-22 Kompozycje bioaktywnego hydrożelu do regenerowania tkanki łącznej PL1677846T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51339203P 2003-10-22 2003-10-22
EP04796100.8A EP1677846B1 (en) 2003-10-22 2004-10-22 Bioactive hydrogel compositions for regenerating connective tissue
PCT/US2004/035046 WO2005042048A2 (en) 2003-10-22 2004-10-22 Bioactive hydrogel compositions for regenerating connective tissue

Publications (1)

Publication Number Publication Date
PL1677846T3 true PL1677846T3 (pl) 2015-02-27

Family

ID=34549273

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04796100T PL1677846T3 (pl) 2003-10-22 2004-10-22 Kompozycje bioaktywnego hydrożelu do regenerowania tkanki łącznej

Country Status (8)

Country Link
US (6) US20050118230A1 (pl)
EP (2) EP1677846B1 (pl)
AU (1) AU2004285480B2 (pl)
CA (1) CA2543255C (pl)
ES (1) ES2522575T3 (pl)
NZ (2) NZ547140A (pl)
PL (1) PL1677846T3 (pl)
WO (1) WO2005042048A2 (pl)

Families Citing this family (177)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
EP1667623B1 (en) * 2003-09-12 2010-11-24 Z-Medica Corporation Partially hydrated hemostatic agent
EP1663090A4 (en) 2003-09-12 2010-07-21 Z Medica Corp HEMOSTATIC AGENT OF CALCIUM ZEOLITE
WO2006050091A2 (en) * 2004-10-28 2006-05-11 Medivas, Llc Bioactive wound dressings and implantable devices and methods of use
CA2558661C (en) 2004-02-06 2012-09-04 Georgia Tech Research Corporation Load bearing biocompatible device
CA2558623C (en) 2004-02-06 2013-04-16 Georgia Tech Research Corporation Surface directed cellular attachment
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US7736669B2 (en) * 2004-11-30 2010-06-15 University Of Washington Porous structures, and methods of use
WO2006062989A1 (en) * 2004-12-07 2006-06-15 Bacterin International, Inc. Three-dimensional cell culsture system
US20060178609A1 (en) * 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
KR20070117589A (ko) 2005-02-15 2007-12-12 버지니아 커먼웰스 유니버시티 급성 지혈 및 급성 상처와 만성 궤양의 치료를 위한 광물기술
EP1865970A4 (en) * 2005-03-23 2010-11-10 Childrens Medical Center MINIMALLY INVASIVE CLINICAL TREATMENT PROCEDURE FOR THE CLOSURE OF NERVE BREAKS
US9326995B2 (en) 2005-04-04 2016-05-03 The Regents Of The University Of California Oxides for wound healing and body repair
US20060282046A1 (en) * 2005-04-13 2006-12-14 Horn Jeffrey L Device and method for subcutaneous delivery of blood clotting agent
US20090148486A1 (en) * 2005-04-28 2009-06-11 Helen Lu Compositions and methods for treating pulp inflammations caused by infection or trauma
WO2006116530A2 (en) * 2005-04-28 2006-11-02 The Trustees Of Columbia University In The City Of New York Compositions and methods for treating pulp inflammations caused by infection or trauma
EP1898881B1 (en) 2005-05-27 2012-04-04 Royer Biomedical, INC. Bioresorbable polymer matrices and methods of making and using the same
WO2007011644A2 (en) * 2005-07-15 2007-01-25 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent tissue
DE602006018023D1 (de) * 2005-08-08 2010-12-16 Angstrom Medica Inc Zementprodukte sowie verfahren zu deren herstellung und verwendung
CN101370531A (zh) 2005-11-17 2009-02-18 生物模拟治疗公司 采用rhPDGF-BB和生物相容性基质的颌面骨增高
US8048443B2 (en) * 2005-12-16 2011-11-01 Cerapedics, Inc. Pliable medical device and method of use
US20090208464A1 (en) * 2006-01-24 2009-08-20 Centeno Christopher J Mesenchymal stem cell isolation and transplantation method and system to be used in a clinical setting
WO2007092622A2 (en) 2006-02-09 2007-08-16 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US20070276308A1 (en) * 2006-05-26 2007-11-29 Huey Raymond J Hemostatic agents and devices for the delivery thereof
US8202532B2 (en) 2006-05-26 2012-06-19 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
DE102006026589A1 (de) * 2006-06-01 2007-12-06 Ossacur Ag Verwendung eines Kollagens mit osteoinduktiven Wirkstoffen zur Behandlung von Sehnen- und/oder Bänderdefekten
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
ES2664229T3 (es) * 2006-06-30 2018-04-18 Biomimetic Therapeutics, Llc Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador
US20080033572A1 (en) * 2006-08-03 2008-02-07 Ebi L.P. Bone graft composites and methods of treating bone defects
EP3181157B1 (en) 2006-11-03 2019-08-14 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
US8080593B2 (en) * 2006-11-29 2011-12-20 University Of Southern California Reversible thermoresponsive adhesives for implants
US20080132604A1 (en) * 2006-11-30 2008-06-05 Terumo Kabushiki Kaisha Poly-(alpha-hydroxy acid) composition and method of producing molded article using the same
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
WO2008095170A1 (en) * 2007-02-01 2008-08-07 The Research Foundation Of State University Of New York A composite hydrogel
EP2586403B1 (en) 2007-02-06 2023-12-27 Pioneer Surgical Technology, Inc. Intervertebral implant devices
US8753391B2 (en) 2007-02-12 2014-06-17 The Trustees Of Columbia University In The City Of New York Fully synthetic implantable multi-phased scaffold
EP2201910B1 (en) * 2007-06-01 2013-04-03 Allergan, Inc. Biological tissue growth support trough induced tensile stress
US10092524B2 (en) * 2008-06-11 2018-10-09 Edge Therapeutics, Inc. Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
US9095562B2 (en) 2007-07-05 2015-08-04 Regenerative Sciences, Inc. Methods and compositions for optimized expansion and implantation of mesenchymal stem cells
EP2192886B1 (en) 2007-08-28 2017-12-20 Pioneer Surgical Technology, Inc. Cement products and methods of making and using the same
US20090162406A1 (en) * 2007-09-05 2009-06-25 Z-Medica Corporation Wound healing with zeolite-based hemostatic devices
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
US20110171607A1 (en) * 2007-10-25 2011-07-14 The Trustees Of Columbia University In The City Of New York Biopulp
US20090130756A1 (en) * 2007-11-20 2009-05-21 Pioneer Surgical Orthobiologics,Inc. Cryopreservation of cells using cross-linked bioactive hydrogel matrix particles
CN101945994A (zh) 2007-12-19 2011-01-12 再生科学有限责任公司 促进干细胞移植和植入的组合物和方法
US9700584B2 (en) * 2007-12-21 2017-07-11 Rti Surgical, Inc. Osteoinductive putties and methods of making and using such putties
ES2422259T3 (es) 2008-02-07 2013-09-10 Biomimetic Therapeutics Inc Composiciones para la osteogénesis por distracción
US8293813B2 (en) * 2008-03-05 2012-10-23 Biomet Manufacturing Corporation Cohesive and compression resistant demineralized bone carrier matrix
US20110052533A1 (en) * 2008-03-14 2011-03-03 Regenerative Sciences, Llc Compositions and Methods for Cartilage Repair
US20100112014A1 (en) * 2008-04-11 2010-05-06 Gilbert Ryan J Novel hydrogel compositions and methods of using
US20110150846A1 (en) * 2008-07-02 2011-06-23 Allergan, Inc. Compositions and methods for tissue filling and regeneration
CA2735173C (en) 2008-09-02 2017-01-10 Tautona Group Lp Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
BR122020000059B8 (pt) 2008-09-09 2021-06-22 Biomimetic Therapeutics Inc composição que compreende uma matriz biocompatível e um fator de crescimento derivado de plaqueta e kit
AR074551A1 (es) 2008-12-05 2011-01-26 Regenerative Sciences Llc Metodos y composiciones para facilitar la reparacion de tejido avascular
US20100168022A1 (en) * 2008-12-11 2010-07-01 Centeno Christopher J Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens
JP2012512846A (ja) * 2008-12-19 2012-06-07 セリェリクス、ソシエダッド、アノニマ 脂肪幹細胞を含んでなる組成物
MY159533A (en) 2009-01-02 2017-01-13 Univ Putra Malaysia Porous bioceramic composition for bone repair
KR20110106440A (ko) * 2009-01-14 2011-09-28 코넬 유니버시티 생체의료 용도를 위한 생분해성 히드로겔의 제법
US20100249924A1 (en) * 2009-03-27 2010-09-30 Allergan, Inc. Bioerodible matrix for tissue involvement
WO2010123946A2 (en) * 2009-04-20 2010-10-28 Allergan, Inc. Silk fibroin hydrogels and uses thereof
AU2010286826B2 (en) * 2009-08-25 2014-05-08 Genzyme Corporation Cartilage repair
US20110076332A1 (en) * 2009-08-27 2011-03-31 Xiaojun Yu Dextran-chitosan based in-situ gelling hydrogels for biomedical applications
US20110054929A1 (en) * 2009-09-01 2011-03-03 Cell Solutions Colorado Llc Stem Cell Marketplace
EP2480075B1 (en) * 2009-09-23 2020-07-01 Glenpharma AB Compositions and methods for inducing or enhancing connective tissue repair
US9113950B2 (en) 2009-11-04 2015-08-25 Regenerative Sciences, Llc Therapeutic delivery device
PT104879B (pt) 2009-12-10 2012-10-17 Univ Do Minho Hidrogel de dextrino para aplicações biomédicas
AU2014218483B2 (en) * 2009-12-13 2017-01-12 Advanced Biologics, Llc Bioactive grafts and composites
EP3417889A1 (en) 2009-12-13 2018-12-26 Amit Prakash Govil Bioactive grafts and composites
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
KR101959571B1 (ko) 2010-02-22 2019-03-18 바이오미메틱 세라퓨틱스, 인크. 건 질환의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
WO2011119468A1 (en) 2010-03-22 2011-09-29 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US8614190B2 (en) 2010-06-30 2013-12-24 Industrial Technology Research Institute Thermal responsive composition for treating bone diseases
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
EP2605762A1 (en) 2010-08-19 2013-06-26 Allergan, Inc. Compositions comprising adipose tissue and a pge2 analogue and their use in the treatment of a soft tissue condition
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods
US9339387B2 (en) * 2010-10-13 2016-05-17 Cibor, Inc. Synthetic bone grafts constructed from carbon foam materials
WO2012068135A1 (en) 2010-11-15 2012-05-24 Zimmer Orthobiologics, Inc. Bone void fillers
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US8637067B1 (en) 2011-03-10 2014-01-28 Lifecell Corporation Elastic tissue matrix derived hydrogel
US9157908B2 (en) 2011-04-22 2015-10-13 University Of Washington Through Its Center For Commercialization Chitosan-alginate scaffold cell culture system and related methods
EP2757964B1 (en) 2011-05-26 2016-05-04 Cartiva, Inc. Tapered joint implant and related tools
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
CA2838237C (en) 2011-06-03 2020-05-26 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130071360A1 (en) 2011-06-29 2013-03-21 Biorestorative Therapies, Inc. Brown Fat Cell Compositions and Methods
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
KR101351515B1 (ko) * 2011-09-23 2014-01-15 전북대학교산학협력단 방사성 핵종이 표지되고 약물이 담지된 고분자 하이드로겔 및 이의 제조방법, 및 이를 유효성분으로 함유하는 암 치료용 약학 조성물
US9132021B2 (en) 2011-10-07 2015-09-15 Pioneer Surgical Technology, Inc. Intervertebral implant
JP2014532713A (ja) * 2011-11-02 2014-12-08 ハルシオン，インコーポレイテッド 創傷処置の方法及び組成物
ITRM20110648A1 (it) * 2011-12-06 2013-06-07 Uni Degli Studi Camerino Materiali elettroattivi per applicazioni biomediche
WO2013086404A1 (en) * 2011-12-09 2013-06-13 The Board Of Trustees Of The Leland Stanford Junior University Decellularized composite tissue bioscaffolds for musculoskeletal tissue interface reconstruction and methods of production
EP3842078A1 (en) 2011-12-20 2021-06-30 LifeCell Corporation Sheet tissue products
US9549805B2 (en) 2011-12-20 2017-01-24 Lifecell Corporation Flowable tissue products
WO2013096650A2 (en) 2011-12-23 2013-06-27 Pioneer Surgical Technology Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith
ES2705823T3 (es) 2012-01-24 2019-03-26 Lifecell Corp Matrices de tejidos alargadas
US20150177115A1 (en) 2012-04-06 2015-06-25 Slingshot Biosciences Hydrogel particles with tunable optical properties
WO2013162997A1 (en) 2012-04-24 2013-10-31 Lifecell Corporation Functionalized tissue matrices
HUE046178T2 (hu) * 2012-05-17 2020-02-28 Cartiheal 2009 Ltd Biomátrix hidrogélek és alkalmazási eljárásaik
US10207027B2 (en) 2012-06-11 2019-02-19 Globus Medical, Inc. Bioactive bone graft substitutes
MX376779B (es) 2012-06-22 2025-03-07 Teleflex Tech Llc Dispositivos hemostaticos.
AU2013341718B2 (en) * 2012-09-18 2017-11-23 Novabone Products, Llc Bioglass with glycosaminoglycans
US10806823B2 (en) * 2013-02-13 2020-10-20 Cartiheal (2009) Ltd. Solid substrates for promoting cell and tissue growth
WO2014164815A2 (en) 2013-03-12 2014-10-09 Allergan, Inc. Adipose tissue combinations, devices, and uses thereof
WO2014169249A1 (en) 2013-04-12 2014-10-16 The Trustees Of Columbia University In The City Of New York Methods for host cell homing and dental pulp regeneration
CA2911102A1 (en) * 2013-05-01 2014-11-06 Halscion, Inc. Hydrogel adapted for treatment of acute dermal wounds
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US9248384B2 (en) 2013-10-02 2016-02-02 Allergan, Inc. Fat processing system
US9539286B2 (en) 2013-10-18 2017-01-10 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9486483B2 (en) 2013-10-18 2016-11-08 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
KR20150053606A (ko) * 2013-11-08 2015-05-18 세원셀론텍(주) 콜라겐과 히알루론산의 천연가교를 통한 고무성질의 물성이 강화된 생체재료물질 및 그 제조방법
US20150216923A1 (en) * 2014-02-05 2015-08-06 Ralph L. Peterson Biochemical Scaffolds for Modulating Cell Function
US9579421B2 (en) 2014-02-07 2017-02-28 Globus Medical Inc. Bone grafts and methods of making and using bone grafts
US9463264B2 (en) 2014-02-11 2016-10-11 Globus Medical, Inc. Bone grafts and methods of making and using bone grafts
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
EP3166624B1 (en) 2014-07-09 2020-06-03 Mayo Foundation for Medical Education and Research Treating rotator cuff conditions
US10722444B2 (en) 2014-09-30 2020-07-28 Allergan Industrie, Sas Stable hydrogel compositions including additives
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
US10238507B2 (en) 2015-01-12 2019-03-26 Surgentec, Llc Bone graft delivery system and method for using same
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
CN114923837A (zh) 2015-02-09 2022-08-19 弹弓生物科学公司 具有可调光学性质的水凝胶颗粒以及使用其的方法
JP7274817B2 (ja) 2015-02-13 2023-05-17 アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ 顎先等の顔面の容貌を造形し、拡張し、または補正するためのインプラント
EP3268063A4 (en) 2015-03-10 2018-10-31 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Multiple needle injector
CA2981061A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
CA2981064C (en) 2015-03-31 2024-01-02 Cartiva, Inc. Carpometacarpal (cmc) implants and methods
EP3282961A4 (en) 2015-04-14 2018-12-05 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
WO2016195462A1 (ko) * 2015-06-05 2016-12-08 국립암센터 전기활성화 전도성 폴리머를 사용한 기능성 세포 시트 및 이의 제조방법
US10016529B2 (en) 2015-06-10 2018-07-10 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US11426489B2 (en) 2015-06-10 2022-08-30 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US10596192B2 (en) * 2015-07-16 2020-03-24 Mayo Foundation For Medical Education And Research Treating rotator cuff conditions
CN108602048B (zh) 2015-12-18 2022-02-18 坎特伯雷大学 分离介质
RU2709154C1 (ru) 2016-04-08 2019-12-16 Аллерган, Инк. Аспирационно-инъекционное устройство
WO2018119493A1 (en) * 2016-12-30 2018-07-05 Commercial Development & Industry Partnerships A synthetic implantable scaffold
CN106730021B (zh) * 2016-12-31 2019-12-10 华南理工大学 一种生物活性玻璃-改性明胶复合水凝胶及其制备方法
GB201708909D0 (en) * 2017-06-05 2017-07-19 Orthox Ltd Implantable tissue repair devices and methods for manufacturing the same
JP7521152B2 (ja) 2017-09-08 2024-07-24 エクスタント メディカル ホールディングス，インコーポレイテッド． 椎間インプラント、器具、及び方法
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
CN107823711B (zh) * 2017-11-09 2020-10-30 华中科技大学同济医学院附属协和医院 核壳结构复合材料的制备及利用其构建组织工程微组织的方法
KR102075596B1 (ko) * 2017-12-04 2020-02-10 이일훈 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물
US20190192437A1 (en) * 2017-12-27 2019-06-27 Industrial Technology Research Institute Powder form and use of hydrogel compositions for alleviating degenerative joint and tendon tear
CN108295303A (zh) * 2018-02-08 2018-07-20 中山大学附属第三医院（中山大学肝脏病医院） 一种钛金属植入物及其制备方法和用途
BR112020017030A2 (pt) * 2018-02-20 2020-12-15 Advanced Aesthetic Technologies, Inc. Hidrogéis de alta concentração e métodos relacionados
US11235086B2 (en) 2018-02-22 2022-02-01 Cerapedics, Inc. Processes for coating inorganic particles with a peptide or protein useful for improving cellular activity related to bone growth
US10687828B2 (en) 2018-04-13 2020-06-23 Surgentec, Llc Bone graft delivery system and method for using same
US11116647B2 (en) 2018-04-13 2021-09-14 Surgentec, Llc Bone graft delivery system and method for using same
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
CZ308845B6 (cs) * 2019-01-21 2021-07-07 Globetech Innovation S.R.O Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran
US20220288273A1 (en) * 2019-06-13 2022-09-15 The Regents Of The University Of California Osteoinductive modified gelatin hydrogels and methods of making and using the same
US11446084B2 (en) 2019-07-12 2022-09-20 Neuralink Corp. Laser drilling of pia mater
KR102099842B1 (ko) * 2019-09-26 2020-04-10 (주)리젠바이오참 조직재생용 하이드로겔 조성물 및 이를 이용하여 제조된 지지체
CN110746516B (zh) * 2019-10-29 2021-06-25 无锡贝迪生物工程股份有限公司 一种基于胶原的天然高分子水凝胶及其制备方法
KR20220129585A (ko) 2020-01-24 2022-09-23 슬링샷 바이오사이언시즈 인코포레이티드 세포-유사 보정 입자를 위한 조성물 및 방법
WO2021226036A1 (en) 2020-05-04 2021-11-11 Slingshot Biosciences, Inc. Compositions and methods for passive optical barcoding for multiplexed assays
IT202000016576A1 (it) 2020-07-08 2022-01-08 Univ Degli Studi Di Brescia Corpo poroso bioattivo tridimensionale per la rigenerazione di tessuto osseo e processo per la sua produzione
US11896736B2 (en) 2020-07-13 2024-02-13 Globus Medical, Inc Biomaterial implants and methods of making the same
CN113499476B (zh) * 2021-07-12 2022-03-18 上海市第一人民医院 协同骨肉瘤治疗和促进骨再生的导电水凝胶支架材料、制备方法及其应用
CN113546211B (zh) * 2021-07-31 2022-08-23 福建省博特生物科技有限公司 一种牛皮制备可注射温敏水凝胶的方法及水凝胶的应用
WO2023076629A1 (en) 2021-10-29 2023-05-04 Slingshot Biosciences, Inc. Hydrogel particles as feeder cells and as synthetic antigen presenting cells
WO2023201431A1 (en) * 2022-04-21 2023-10-26 Oligo Médic Inc. Self-healing injectable super-lubricating hydrogels and biomedical applications thereof
AU2023280490A1 (en) 2022-06-02 2024-12-05 Slingshot Biosciences, Inc. Apoptotic cell mimic
WO2024092161A2 (en) 2022-10-26 2024-05-02 Slingshot Biosciences, Inc. Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation
US12285541B2 (en) 2023-01-26 2025-04-29 Insignia Pharmaceuticals, Llc Pharmaceutical compositions for treating osteoarthritis
CN118204495B (zh) * 2024-02-03 2024-08-20 哈尔滨工业大学（威海） 一种多孔钽融合器及其制备方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520821A (en) * 1982-04-30 1985-06-04 The Regents Of The University Of California Growing of long-term biological tissue correction structures in vivo
GB8328074D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compositions
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5306500A (en) * 1988-11-21 1994-04-26 Collagen Corporation Method of augmenting tissue with collagen-polymer conjugates
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5800541A (en) * 1988-11-21 1998-09-01 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5073373A (en) * 1989-09-21 1991-12-17 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5290558A (en) * 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5645591A (en) * 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
CS277533B6 (en) * 1990-12-29 1993-03-17 Krajicek Milan Fixed osteaosynthesis appliance
US6352707B1 (en) * 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US5824331A (en) * 1992-02-24 1998-10-20 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US6231881B1 (en) * 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
DE69534640T2 (de) * 1994-04-29 2006-08-10 Scimed Life Systems, Inc., Maple Grove Stent mit Kollagen
US5783214A (en) * 1994-06-13 1998-07-21 Buford Biomedical, Inc. Bio-erodible matrix for the controlled release of medicinals
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US6132759A (en) * 1996-05-03 2000-10-17 Innogenetics N.V. Medicaments containing gelatin cross-linked with oxidized polysaccharides
US5866165A (en) * 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
WO1999042147A1 (en) * 1998-02-23 1999-08-26 Massachusetts Institute Of Technology Biodegradable shape memory polymers
US7045141B2 (en) * 1998-02-27 2006-05-16 Musculoskeletal Transplant Foundation Allograft bone composition having a gelatin binder
EP1056836B1 (en) 1998-02-27 2009-02-18 Purdue Research Foundation Submucosa gel compositions
US6113629A (en) * 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
EP1095159A4 (en) * 1998-07-15 2003-01-02 Human Genome Sciences Inc Bone Morphogenetic Protein
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
US6696410B1 (en) * 1999-09-27 2004-02-24 Stryker Corporation Compositions and therapeutic methods using morphogenic proteins, hormones and hormone receptors
AU2001238695B2 (en) * 2000-02-26 2005-11-24 Artecel Sciences, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
US7291673B2 (en) * 2000-06-02 2007-11-06 Eidgenossiche Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US6902881B2 (en) * 2000-10-13 2005-06-07 President And Fellows Of Harvard College Compounds and methods for regulating cell differentiation
CA2365376C (en) * 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US20020176893A1 (en) * 2001-02-02 2002-11-28 Wironen John F. Compositions, implants, methods, and kits for closure of lumen openings, repair of ruptured tissue, and for bulking of tissue
WO2003072155A1 (en) * 2002-02-21 2003-09-04 Encelle, Inc. Cross-linked bioactive hydrogel matrices
CA2489712C (en) * 2002-06-21 2016-07-12 University Of Utah Research Foundation Crosslinked compounds and methods of making and using thereof
CN101632843A (zh) * 2002-08-20 2010-01-27 精密技术公司 骨生长诱导材料的携带和输送用组合物以及生产和应用该组合物的方法
US7862831B2 (en) * 2002-10-09 2011-01-04 Synthasome, Inc. Method and material for enhanced tissue-biomaterial integration

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