[go: up one dir, main page]

PE35596A1 - Triterpeno tetraciclico - Google Patents

Triterpeno tetraciclico

Info

Publication number
PE35596A1
PE35596A1 PE1995274759A PE27475995A PE35596A1 PE 35596 A1 PE35596 A1 PE 35596A1 PE 1995274759 A PE1995274759 A PE 1995274759A PE 27475995 A PE27475995 A PE 27475995A PE 35596 A1 PE35596 A1 PE 35596A1
Authority
PE
Peru
Prior art keywords
dammara
compound
refers
formula
triterpen
Prior art date
Application number
PE1995274759A
Other languages
English (en)
Inventor
Lukas Oberer
Laszlo Revesz
Hans-Ulrich Nageli
Hans-Jorg Roth
Peter Hiestand
Reto Naef
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE35596A1 publication Critical patent/PE35596A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0014—Androstane derivatives substituted in position 17 alfa, not substituted in position 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UN COMPUESTO DAMMARA DE FORMULA Ia DONDE: a SIGNIFICA >CH-OR1; R1 SIGNIFICA HIDROGENO, UN RESIDUO DE ACILO o >C=O; R ES UN GRUPO C8 ALIFATICO QUE COMPRENDE EVENTUALMENTE UNO O DOS DOBLES ENLACES QUE PUEDE ESTAR SUSTITUIDO CON UN GRUPO HIDROXI; UN COMPUESTO PREFERIDO ES EL DE FORMULA Ic [(17 ALFA)-23-(E)-DAMMARA 20, 23-DIEN-3 BETA, 25-DIOL] O UN ESTER DEL MISMO, CON UN ESPECTRO NMR CARACTERISTICO. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION QUE COMPRENDE: a) EPIMERIZACION DE UN COMPUESTO 17-BETACARBONIL-DAMMARA PARA OBTENER UN COMPUESTO 17 ALFACARBONIL DAMMARA, Y SI SE REQUIERE; b) LA ULTERIOR DERIVATIZACION DE 17 ALFA CARBONIL-DAMMARA UTILIZANDO METODOS CONOCIDOS. ESTE COMPUESTO SE CARACTERIZA POR SUS PROPIEDADES INMUNOSUPRESORAS Y ANTIINFLAMATORIAS
PE1995274759A 1994-07-27 1995-07-26 Triterpeno tetraciclico PE35596A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9415161A GB9415161D0 (en) 1994-07-27 1994-07-27 Organic compounds

Publications (1)

Publication Number Publication Date
PE35596A1 true PE35596A1 (es) 1996-09-04

Family

ID=10758967

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1995274759A PE35596A1 (es) 1994-07-27 1995-07-26 Triterpeno tetraciclico

Country Status (20)

Country Link
US (1) US5852005A (es)
EP (1) EP0801653A2 (es)
JP (1) JPH10503191A (es)
AU (1) AU704929B2 (es)
BR (1) BR9508344A (es)
CA (1) CA2192789A1 (es)
CZ (1) CZ23497A3 (es)
FI (1) FI970320A (es)
GB (1) GB9415161D0 (es)
HU (1) HUT76831A (es)
IL (1) IL114723A0 (es)
MX (1) MX9700554A (es)
NO (1) NO970329L (es)
NZ (1) NZ290430A (es)
PE (1) PE35596A1 (es)
PL (1) PL318145A1 (es)
SK (1) SK11897A3 (es)
TR (1) TR199500905A2 (es)
WO (1) WO1996003419A1 (es)
ZA (1) ZA956279B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6124362A (en) * 1998-07-17 2000-09-26 The Procter & Gamble Company Method for regulating hair growth
US6450168B1 (en) 2001-04-17 2002-09-17 Kellie I. Nguyen Infant sleeping blanket/garment for use with medical devices
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
CN109985052A (zh) * 2017-12-29 2019-07-09 上海蓝木化工有限公司 三萜类化合物的新用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3644421A (en) * 1968-12-02 1972-02-22 Syntex Corp 4-oxa-3-keto-delta**1-pregnene derivatives
US3868453A (en) * 1970-03-04 1975-02-25 Philips Corp 16-Methylene-9/beta, 10alpha-steroid compounds, pharmaceutical preparations which contain the novel compounds as active ingredients and methods of producing the said compounds and preparations
US4057543A (en) * 1976-07-01 1977-11-08 G. D. Searle & Co. Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone
US4636496A (en) * 1984-03-20 1987-01-13 Wayne State University Compositions inhibiting murine MXT ductal carcinoma
US4755504A (en) * 1985-10-03 1988-07-05 Yaguang Liu Pharmaceutical composition from Tienchi
JPH04243833A (ja) * 1991-01-28 1992-08-31 Tsumura & Co １１β−ヒドロキシステロイドデヒドロゲナーゼ阻害剤

Also Published As

Publication number Publication date
NO970329D0 (no) 1997-01-24
FI970320A0 (fi) 1997-01-24
JPH10503191A (ja) 1998-03-24
CZ23497A3 (en) 1997-07-16
WO1996003419A1 (en) 1996-02-08
PL318145A1 (en) 1997-05-12
TR199500905A2 (tr) 1996-06-21
FI970320A (fi) 1997-01-24
US5852005A (en) 1998-12-22
BR9508344A (pt) 1998-07-14
IL114723A0 (en) 1995-11-27
ZA956279B (en) 1997-01-27
NO970329L (no) 1997-03-25
GB9415161D0 (en) 1994-09-14
EP0801653A3 (es) 1997-10-29
SK11897A3 (en) 1997-08-06
AU3116695A (en) 1996-02-22
AU704929B2 (en) 1999-05-06
NZ290430A (en) 1998-01-26
EP0801653A2 (en) 1997-10-22
HUT76831A (en) 1997-11-28
CA2192789A1 (en) 1996-02-08
MX9700554A (es) 1997-05-31

Similar Documents

Publication Publication Date Title
ES2157593T3 (es) Derivados de la adenosina heterociclicos sustituidos en n6.
SE8104132L (sv) Mjuka steroider med antiiflammatorisk verkan
ES2003843A4 (es) Proyectil perforante con nucleo duro y guia ductil y su procedimientode fabricacion.
ZA882140B (en) Novel alpha-aminoacetophenones as photoinitiators
ES2183847T3 (es) Composiciones a base de agua que contienen organopolisiloxano, procedimiento para su elaboracion y su uso.
PE35596A1 (es) Triterpeno tetraciclico
EP0283436A3 (en) Perylene-tetracarboxylic-acid diimides with long-chain residue containing carbonyl groups
MX7992A (es) Pinturas o lubricantes que contienen inhibidores de corrosion fenolicos.
AR001932A1 (es) Un hidrosol de una sal de un complejo procedimiento para su obtención una dispersion de éster polivínilico un procedimiento para su obtención y el usode mismo
ES2039322T5 (es) Perfil de estructura con un accesorio de equipo.
BR9302426A (pt) Processo para a separacao de uma mistura anomerica
DE3575715D1 (de) Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel.
ES2195312T3 (es) Copolimeros de alfa-olefina-cicloolefina y procedimiento para su preparacion.
ES2063313T3 (es) Nuevos acidos omega-fenilamino alcanoicos sustituidos en el nucleo aromatico por un radical derivado de 19-noresteroides, sus sales, su procedimiento de preparacion y los compuestos intermedios de este procedimiento, su aplicacion como medicamentos y composiciones que los contien
DE69432623D1 (de) Kationen-Sensor-Verbundstruktur und Verbindungen zur Verwendung darin
DK165987C (da) 14-azido-steroider, der er anvendelige som mellemprodukter
ES479667A1 (es) Un procedimiento para la preparacion de derivados de karra- micina.
GR1002598B (el) Παραγωγα επι-επιβατιδινης.
MX9202972A (es) Nuevos esteroides sustituidos con metilo en la posicion 16 derivados de la pregna-1, 4-dieno-3,20-diona, su preparacion, su aplicacion a la preparacion de esteroides sustituidos con metileno en la posicion 16, y nuevos compuestos intermedios.
SE8005575L (sv) Farmaceutisk komposition innehallande derivat av aminobensoesyra for reglering av prostaglandiner
MX169085B (es) Composicion de material para camara a base de hule curable
DK37782A (da) Fremgangsmaade til fremstilling af 17alfa-hydroxy-17beta-hydroxyacetylsteroider
ES476024A1 (es) Un procedimiento para preparar derivados de cefalosporina
CO4810308A1 (es) Procedimiento para la obtencion de fenilcetoenoles 2 y 2,5 sustituidos y compuesto intermedio para realizar dicho procedimiento
ES2070230T3 (es) Compuesto mesomorfico, composicion de cristal liquido que contiene el mismo y dispositivo de cristal liquido que lo utiliza.

Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed