NO994146L - Celleoverflatemolekyl som formidler celleadhesjon og signatransmisjon - Google Patents
Celleoverflatemolekyl som formidler celleadhesjon og signatransmisjonInfo
- Publication number
- NO994146L NO994146L NO994146A NO994146A NO994146L NO 994146 L NO994146 L NO 994146L NO 994146 A NO994146 A NO 994146A NO 994146 A NO994146 A NO 994146A NO 994146 L NO994146 L NO 994146L
- Authority
- NO
- Norway
- Prior art keywords
- cell surface
- surface molecule
- surface molecules
- cell
- mediates
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 title abstract 6
- 230000021164 cell adhesion Effects 0.000 title abstract 2
- 230000005540 biological transmission Effects 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 2
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 230000000527 lymphocytic effect Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Rehabilitation Therapy (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Record Carriers (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6229097 | 1997-02-27 | ||
JP06221798A JP3521382B2 (ja) | 1997-02-27 | 1998-02-26 | 細胞間接着及びシグナル伝達を媒介する細胞表面分子 |
PCT/JP1998/000837 WO1998038216A1 (fr) | 1997-02-27 | 1998-02-27 | Molecule de surface cellulaire induisant l'adhesion cellulaire et la transmission de signaux |
Publications (3)
Publication Number | Publication Date |
---|---|
NO994146D0 NO994146D0 (no) | 1999-08-26 |
NO994146L true NO994146L (no) | 1999-10-27 |
NO327500B1 NO327500B1 (no) | 2009-07-20 |
Family
ID=26403281
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19994146A NO327500B1 (no) | 1997-02-27 | 1999-08-26 | Polypeptid som utgjor et celleoverflatemolekyl, polypeptidfragment, gen, vektor, transformant, fusjonspolypeptid, homodimert molekyl, farmasoytisk preparat, antistoff, eller del av dette, hybridom, transgen mus samt knockout-mus. |
NO20073155A NO331064B1 (no) | 1997-02-27 | 2007-06-20 | Farmasoytisk preparat |
NO20092369A NO20092369L (no) | 1997-02-27 | 2009-06-18 | Polypeptid som utgjor et celleoverflatemolekyl, polypeptidfragment, gen, vektor, transformant, fusjonspolypeptid, homodimert molekyl, farmasoytisk preparat, antistoff eller del av dette, hybridom og transgen mus |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073155A NO331064B1 (no) | 1997-02-27 | 2007-06-20 | Farmasoytisk preparat |
NO20092369A NO20092369L (no) | 1997-02-27 | 2009-06-18 | Polypeptid som utgjor et celleoverflatemolekyl, polypeptidfragment, gen, vektor, transformant, fusjonspolypeptid, homodimert molekyl, farmasoytisk preparat, antistoff eller del av dette, hybridom og transgen mus |
Country Status (20)
Country | Link |
---|---|
US (10) | US7030225B1 (no) |
EP (2) | EP0984023B9 (no) |
JP (1) | JP3521382B2 (no) |
KR (1) | KR100349388B1 (no) |
CN (3) | CN100400546C (no) |
AT (1) | ATE360645T1 (no) |
AU (1) | AU732378B2 (no) |
BR (1) | BR9807788B1 (no) |
CA (1) | CA2282727C (no) |
DE (1) | DE69837658T2 (no) |
DK (1) | DK0984023T3 (no) |
ES (1) | ES2285763T3 (no) |
HK (2) | HK1026433A1 (no) |
ID (1) | ID23386A (no) |
IL (3) | IL131584A0 (no) |
NO (3) | NO327500B1 (no) |
NZ (1) | NZ337425A (no) |
PT (1) | PT984023E (no) |
SI (1) | SI0984023T1 (no) |
WO (1) | WO1998038216A1 (no) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7112655B1 (en) | 1997-02-27 | 2006-09-26 | Japan Tobacco, Inc. | JTT-1 protein and methods of inhibiting lymphocyte activation |
JP3521382B2 (ja) | 1997-02-27 | 2004-04-19 | 日本たばこ産業株式会社 | 細胞間接着及びシグナル伝達を媒介する細胞表面分子 |
WO1999015553A2 (de) * | 1997-09-23 | 1999-04-01 | Bundesrepublik Deutschland Letztvertreten Durch Den Direktor Des Robert-Koch-Instituts | Ko-stimulierendes polypeptid von t-zellen, monoklonale antikörper sowie die herstellung und deren verwendung |
DE19821060A1 (de) | 1997-09-23 | 1999-04-15 | Bundesrepublik Deutschland Let | Ko-stimulierendes Polypeptid von T-Zellen, monoklonale Antikörper sowie die Herstellung und deren Verwendung |
EP1119253A4 (en) * | 1998-10-07 | 2005-12-21 | Millennium Pharm Inc | NEW SPECIFIC MOLECULES OF Th2 AND USES THEREOF |
US8624010B1 (en) | 1999-02-03 | 2014-01-07 | Steven K. Yoshinaga | Nucleic acids encoding B7RP1 |
AU773954B2 (en) * | 1999-02-03 | 2004-06-10 | Amgen, Inc. | Novel Polypeptides involved in immune response |
US7435796B1 (en) | 1999-02-03 | 2008-10-14 | Amgen Inc. | Antibodies which bind B7RP1 |
US7708993B2 (en) | 1999-02-03 | 2010-05-04 | Amgen Inc. | Polypeptides involved in immune response |
WO2001008700A1 (en) | 1999-07-28 | 2001-02-08 | Genetics Institute, Inc. | Preventing immune-mediated abortion by inhibiting costimulation |
ES2539411T3 (es) | 1999-08-23 | 2015-06-30 | Dana-Farber Cancer Institute, Inc. | PD-1, receptor para la B7-4 y su utilización |
JP3871503B2 (ja) | 1999-08-30 | 2007-01-24 | 日本たばこ産業株式会社 | 免疫性疾患治療剤 |
JP4210454B2 (ja) | 2001-03-27 | 2009-01-21 | 日本たばこ産業株式会社 | 炎症性腸疾患治療剤 |
ES2290052T3 (es) | 1999-09-21 | 2008-02-16 | Genetics Institute, Llc | Moleculas gl50 y usos para las mismas. |
US7718644B2 (en) * | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
US6489125B1 (en) * | 2000-05-10 | 2002-12-03 | The Trustees Of Columbia University In The City Of New York | Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor |
US20040048780A1 (en) * | 2000-05-10 | 2004-03-11 | The Trustees Of Columbia University In The City Of New York | Method for treating and preventing cardiac arrhythmia |
US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US7879840B2 (en) * | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US20060293266A1 (en) * | 2000-05-10 | 2006-12-28 | The Trustees Of Columbia | Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure |
US7393652B2 (en) * | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
JP3543966B2 (ja) * | 2000-05-18 | 2004-07-21 | 日本たばこ産業株式会社 | 副刺激伝達分子ailimに対するヒトモノクローナル抗体及びその医薬用途 |
JP3597140B2 (ja) | 2000-05-18 | 2004-12-02 | 日本たばこ産業株式会社 | 副刺激伝達分子ailimに対するヒトモノクローナル抗体及びその医薬用途 |
US7094874B2 (en) | 2000-05-26 | 2006-08-22 | Bristol-Myers Squibb Co. | Soluble CTLA4 mutant molecules |
KR100895134B1 (ko) * | 2000-05-26 | 2009-05-04 | 브리스톨-마이어스스퀴브컴파니 | 가용성 ctla4 돌연변이 분자 및 그의 용도 |
AU2002308267A1 (en) * | 2001-01-16 | 2002-10-03 | Bayer Aktiengesellschaft | Regulation of human icos v protein |
NZ526507A (en) * | 2001-01-26 | 2005-07-29 | Commw Scient Ind Res Org | Methods and means for producing efficient silencing construct using recombinational cloning |
JP4212278B2 (ja) * | 2001-03-01 | 2009-01-21 | 日本たばこ産業株式会社 | 移植片拒絶反応抑制剤 |
WO2002079499A1 (en) | 2001-04-02 | 2002-10-10 | Wyeth | Pd-1, a receptor for b7-4, and uses therefor |
JP2005505258A (ja) * | 2001-06-21 | 2005-02-24 | イシス・イノベイション・リミテッド | アトピーにおけるange遺伝子 |
EP1456652A4 (en) | 2001-11-13 | 2005-11-02 | Dana Farber Cancer Inst Inc | IMMUNOCELL ACTIVATION MODULATING SUBSTANCES AND USE METHOD THEREFOR |
US7544678B2 (en) * | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
US8710045B2 (en) * | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
WO2005103086A1 (en) | 2004-04-23 | 2005-11-03 | Bundesrepublik Deutschland letztvertreten durch das Robert-Koch-Institut vertreten durch seinen Präsidenten | Method for the treatment of t cell mediated conditions by depletion of icos-positive cells in vivo |
US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
EP2031062B1 (en) | 2006-06-07 | 2018-10-24 | The University of Tokyo | Dna encoding polypeptide capable of modulating muscle-specific tyrosine kinase activity |
WO2008149794A1 (ja) | 2007-05-30 | 2008-12-11 | Hoya Corporation | 眼内レンズ挿入器具 |
WO2008149795A1 (ja) | 2007-05-30 | 2008-12-11 | Hoya Corporation | 眼内レンズ挿入器具 |
EP2160796B1 (en) * | 2007-06-22 | 2017-04-05 | Nokia Technologies Oy | An antenna arrangement |
JP5086713B2 (ja) | 2007-07-11 | 2012-11-28 | Hoya株式会社 | 眼内レンズ挿入器具 |
EP2221065B1 (en) | 2007-11-26 | 2016-12-28 | Japan Science and Technology Agency | Therapeutic or prophylactic agent, detection method and detection agent for metabolic syndrome, and method for screening of candidate compound for therapeutic agent for metabolic syndrome |
PL2342226T3 (pl) | 2008-09-26 | 2017-01-31 | Dana-Farber Cancer Institute, Inc. | Ludzkie przeciwciała anty-PD-1, PD-L1 i PD-L2 oraz ich zastosowania |
EP2455396A4 (en) | 2009-07-16 | 2013-05-01 | Otsuka Chemical Co Ltd | EXTRACELLULAR AILIM DOMAIN PLACED WITH SUGAR CHAINS AND METHOD OF MANUFACTURING THE SAME |
US20130042873A1 (en) | 2010-03-09 | 2013-02-21 | Klaus Bechgaard | Contraceptive device |
US8642557B2 (en) | 2010-03-12 | 2014-02-04 | Abbvie Biotherapeutics Inc. | CTLA4 proteins and their uses |
PL2925350T3 (pl) | 2012-12-03 | 2019-07-31 | Bristol-Myers Squibb Company | Zwiększenie aktywności przeciwnowotworowej immunomodulacyjnych białek fuzyjnych fc |
US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
PH12022550138A1 (en) | 2013-03-13 | 2023-03-06 | Amgen Inc | Proteins specific for baff and b7rp1 and uses thereof |
AU2014275166B2 (en) | 2013-06-06 | 2020-09-10 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for identification, assessment prevention, and treatment of cancer using PD-L1 isoforms |
GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
MA41414A (fr) | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
ITUB20151014A1 (it) * | 2015-05-27 | 2016-11-27 | Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro | Ligandi del recettore b7h nel trattamento di osteopenia e osteoporosi |
WO2017190100A1 (en) * | 2016-04-28 | 2017-11-02 | The Trustees Of Dartmouth College | Nucleic acid constructs for co-expression of chimeric antigen receptor and transcription factor, cells containing and therapeutic use thereof |
WO2018029474A2 (en) | 2016-08-09 | 2018-02-15 | Kymab Limited | Anti-icos antibodies |
US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
WO2017220990A1 (en) | 2016-06-20 | 2017-12-28 | Kymab Limited | Anti-pd-l1 antibodies |
US11858996B2 (en) | 2016-08-09 | 2024-01-02 | Kymab Limited | Anti-ICOS antibodies |
WO2018043707A1 (ja) | 2016-09-02 | 2018-03-08 | 学校法人慶應義塾 | 視覚機能再生剤又は視覚機能低下予防剤 |
US11779604B2 (en) | 2016-11-03 | 2023-10-10 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses and methods |
TWI788340B (zh) | 2017-04-07 | 2023-01-01 | 美商必治妥美雅史谷比公司 | 抗icos促效劑抗體及其用途 |
GB201709808D0 (en) | 2017-06-20 | 2017-08-02 | Kymab Ltd | Antibodies |
WO2019122882A1 (en) | 2017-12-19 | 2019-06-27 | Kymab Limited | Bispecific antibody for icos and pd-l1 |
GB201721338D0 (en) | 2017-12-19 | 2018-01-31 | Kymab Ltd | Anti-icos Antibodies |
EP3502140A1 (en) * | 2017-12-21 | 2019-06-26 | F. Hoffmann-La Roche AG | Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules |
PE20210665A1 (es) | 2018-03-23 | 2021-03-31 | Bristol Myers Squibb Co | Anticuerpos contra mica y/o micb y sus usos |
JOP20210298A1 (ar) | 2019-05-14 | 2023-01-30 | Provention Bio Inc | طرق وتركيبات للوقاية من مرض السكري من النوع الأول |
EP3976831A1 (en) | 2019-05-30 | 2022-04-06 | Bristol-Myers Squibb Company | Multi-tumor gene signatures for suitability to immuno-oncology therapy |
US20220233691A1 (en) | 2019-05-30 | 2022-07-28 | Bristol-Myers Squibb Company | Cell localization signature and combination therapy |
KR20220016155A (ko) | 2019-05-30 | 2022-02-08 | 브리스톨-마이어스 스큅 컴퍼니 | 면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법 |
US11771741B2 (en) | 2019-09-13 | 2023-10-03 | Restore Vision Inc. | Nucleic acid construct that encodes chimeric rhodopsin |
JPWO2021049634A1 (no) | 2019-09-13 | 2021-03-18 | ||
KR20220088752A (ko) | 2019-10-28 | 2022-06-28 | 메드임뮨 리미티드 | 흉선 기질 림포포이에틴 (tslp)-결합 항체들의 건조 분말 제형 및 이의 사용 방법 |
GB202007099D0 (en) | 2020-05-14 | 2020-07-01 | Kymab Ltd | Tumour biomarkers for immunotherapy |
CA3182445A1 (en) | 2020-06-11 | 2021-12-16 | Francisco Leon | Methods and compositions for preventing type 1 diabetes |
EP4204453A1 (en) | 2020-08-31 | 2023-07-05 | Bristol-Myers Squibb Company | Cell localization signature and immunotherapy |
EP4215212A4 (en) | 2020-09-17 | 2024-04-24 | Restore Vision Inc. | COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES, DISORDERS OR CONDITIONS ASSOCIATED WITH ENDOPLASTIC RETICULUM STRESS OR ALL-TRANS-RETINOAL |
WO2022120179A1 (en) | 2020-12-03 | 2022-06-09 | Bristol-Myers Squibb Company | Multi-tumor gene signatures and uses thereof |
JP2024503265A (ja) | 2020-12-28 | 2024-01-25 | ブリストル-マイヤーズ スクイブ カンパニー | 抗体組成物およびその使用の方法 |
MX2023007650A (es) | 2020-12-28 | 2023-09-11 | Bristol Myers Squibb Co | Metodos de tratamiento de tumores. |
US20240376224A1 (en) | 2021-04-02 | 2024-11-14 | The Regents Of The University Of California | Antibodies against cleaved cdcp1 and uses thereof |
TW202313682A (zh) | 2021-05-18 | 2023-04-01 | 英商凱麥博有限公司 | 抗icos抗體之用途 |
GB202107994D0 (en) | 2021-06-04 | 2021-07-21 | Kymab Ltd | Treatment of cancer |
WO2023178329A1 (en) | 2022-03-18 | 2023-09-21 | Bristol-Myers Squibb Company | Methods of isolating polypeptides |
WO2023222854A1 (en) | 2022-05-18 | 2023-11-23 | Kymab Limited | Uses of anti-icos antibodies |
WO2023235847A1 (en) | 2022-06-02 | 2023-12-07 | Bristol-Myers Squibb Company | Antibody compositions and methods of use thereof |
WO2024054992A1 (en) | 2022-09-09 | 2024-03-14 | Bristol-Myers Squibb Company | Methods of separating chelator |
WO2024196952A1 (en) | 2023-03-20 | 2024-09-26 | Bristol-Myers Squibb Company | Tumor subtype assessment for cancer therapy |
WO2025038763A1 (en) | 2023-08-15 | 2025-02-20 | Bristol-Myers Squibb Company | Ceramic hydroxyapatite chromatography flow through method |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US182667A (en) * | 1876-09-26 | Improvement in flue-stoppers | ||
US177191A (en) * | 1876-05-09 | Improvement in lamps | ||
US164697A (en) * | 1875-06-22 | Improvement in cloth-steaming machines | ||
NZ218336A (en) * | 1985-12-09 | 1991-08-27 | Kirin Amgen Inc | Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf) |
US5506126A (en) | 1988-02-25 | 1996-04-09 | The General Hospital Corporation | Rapid immunoselection cloning method |
SE8801537D0 (sv) * | 1988-04-26 | 1988-04-26 | Ellco Food Ab | Cellodlingsmedium samt forfarande for dess framstellning |
US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
US5580756A (en) | 1990-03-26 | 1996-12-03 | Bristol-Myers Squibb Co. | B7Ig fusion protein |
US5770197A (en) | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
US5504126A (en) * | 1991-11-07 | 1996-04-02 | Safas Corporation | Mineral-like coating and methods of using same |
US5484892A (en) * | 1993-05-21 | 1996-01-16 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells |
US6719972B1 (en) | 1994-06-03 | 2004-04-13 | Repligen Corporation | Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies |
US5914112A (en) | 1996-01-23 | 1999-06-22 | Genentech, Inc. | Anti-CD18 antibodies in stroke |
ATE222774T1 (de) | 1996-01-23 | 2002-09-15 | Genentech Inc | Antikörper gegen cd 18 zur verwendung gegen gehirnschlag |
PT928197E (pt) | 1996-09-18 | 2003-06-30 | Zetesis Spa | Utilizacao de proteinas como agentes contra doencas de natureza autoimunitaria |
KR100510604B1 (ko) | 1996-11-08 | 2005-08-31 | 아이덱 파마슈티칼즈 코포레이션 | 특정 항체와 사람 b7.1 및 b7.2의 공동 자극 항원간의 특이한 결합 상호작용의 확인 방법 |
AU4145597A (en) | 1997-02-20 | 1998-09-09 | Cedars-Sinai Medical Center | Ulcerative colitis panca secretory vesicle antigen and methods of using sa me |
US7112655B1 (en) | 1997-02-27 | 2006-09-26 | Japan Tobacco, Inc. | JTT-1 protein and methods of inhibiting lymphocyte activation |
JP3521382B2 (ja) * | 1997-02-27 | 2004-04-19 | 日本たばこ産業株式会社 | 細胞間接着及びシグナル伝達を媒介する細胞表面分子 |
WO2001032675A1 (en) | 1999-10-29 | 2001-05-10 | Human Genome Sciences, Inc. | 32 human secreted proteins |
DK0973804T3 (da) | 1997-04-07 | 2007-05-07 | Genentech Inc | Anti-VEGF-antistoffer |
DE19821060A1 (de) | 1997-09-23 | 1999-04-15 | Bundesrepublik Deutschland Let | Ko-stimulierendes Polypeptid von T-Zellen, monoklonale Antikörper sowie die Herstellung und deren Verwendung |
WO1999015553A2 (de) * | 1997-09-23 | 1999-04-01 | Bundesrepublik Deutschland Letztvertreten Durch Den Direktor Des Robert-Koch-Instituts | Ko-stimulierendes polypeptid von t-zellen, monoklonale antikörper sowie die herstellung und deren verwendung |
JPH11228442A (ja) | 1998-02-09 | 1999-08-24 | Cypros Pharmaceut Corp | 臓器移植後のシクロスポリン投与量を低減するためのフルクトース二リン酸の使用 |
JP2000154151A (ja) | 1998-09-14 | 2000-06-06 | Kyo Jo | 免疫抑制剤 |
EP1119253A4 (en) | 1998-10-07 | 2005-12-21 | Millennium Pharm Inc | NEW SPECIFIC MOLECULES OF Th2 AND USES THEREOF |
AU773954B2 (en) | 1999-02-03 | 2004-06-10 | Amgen, Inc. | Novel Polypeptides involved in immune response |
BR0010711A (pt) | 1999-05-06 | 2002-02-13 | Genetics Inst | Uso de moléculas co-estimulatórias solúveis para intensificar respostas imunes |
WO2001008700A1 (en) | 1999-07-28 | 2001-02-08 | Genetics Institute, Inc. | Preventing immune-mediated abortion by inhibiting costimulation |
WO2001012658A2 (en) | 1999-08-11 | 2001-02-22 | Isis Innovations Limited | Human icos ligand and application thereof |
JP4210454B2 (ja) | 2001-03-27 | 2009-01-21 | 日本たばこ産業株式会社 | 炎症性腸疾患治療剤 |
JP3871503B2 (ja) | 1999-08-30 | 2007-01-24 | 日本たばこ産業株式会社 | 免疫性疾患治療剤 |
CA2383800A1 (en) | 1999-09-03 | 2001-03-15 | Human Genome Sciences Inc. | 52 human secreted proteins |
ES2290052T3 (es) | 1999-09-21 | 2008-02-16 | Genetics Institute, Llc | Moleculas gl50 y usos para las mismas. |
WO2001064704A1 (en) | 2000-03-02 | 2001-09-07 | Mayo Foundation For Medical Education And Research | hB7-H2, A NOVEL CO-STIMULATORY MOLECULE |
JP3597140B2 (ja) | 2000-05-18 | 2004-12-02 | 日本たばこ産業株式会社 | 副刺激伝達分子ailimに対するヒトモノクローナル抗体及びその医薬用途 |
EP2351840A1 (en) | 2000-11-28 | 2011-08-03 | Amgen Inc. | Polypeptides involved in immune response |
JP4212278B2 (ja) | 2001-03-01 | 2009-01-21 | 日本たばこ産業株式会社 | 移植片拒絶反応抑制剤 |
US20040001831A1 (en) * | 2002-06-26 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Methods and compositions for the diagnosis and treatment of demyelinating inflammatory disorders |
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- 1998-02-27 EP EP04022364.6A patent/EP1502920B1/en not_active Expired - Lifetime
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1999
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- 1999-08-26 US US09/383,551 patent/US7030225B1/en not_active Expired - Lifetime
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2000
- 2000-09-06 HK HK00105622A patent/HK1026433A1/xx not_active IP Right Cessation
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2002
- 2002-11-21 US US10/301,056 patent/US20030083472A1/en not_active Abandoned
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2003
- 2003-11-07 US US10/704,030 patent/US7279560B2/en not_active Expired - Fee Related
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2004
- 2004-03-05 US US10/794,344 patent/US7259147B2/en not_active Expired - Fee Related
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2007
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