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NO985375D0 - Benzofurankarboksamider og deres terapeutiske anvendelse - Google Patents

Benzofurankarboksamider og deres terapeutiske anvendelse

Info

Publication number
NO985375D0
NO985375D0 NO985375A NO985375A NO985375D0 NO 985375 D0 NO985375 D0 NO 985375D0 NO 985375 A NO985375 A NO 985375A NO 985375 A NO985375 A NO 985375A NO 985375 D0 NO985375 D0 NO 985375D0
Authority
NO
Norway
Prior art keywords
alkyl
heteroaryl
heterocyclo
optionally substituted
heterocyclyl
Prior art date
Application number
NO985375A
Other languages
English (en)
Norwegian (no)
Other versions
NO985375L (no
Inventor
Hazel Joan Dyke
John Gary Montana
Christopher Lowe
Hannah Jayne Kendall
Verity Margaret Sabin
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9610515.0A external-priority patent/GB9610515D0/en
Priority claimed from PCT/GB1996/003012 external-priority patent/WO1997020833A1/en
Priority claimed from GBGB9708070.9A external-priority patent/GB9708070D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of NO985375L publication Critical patent/NO985375L/no
Publication of NO985375D0 publication Critical patent/NO985375D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO985375A 1996-05-20 1998-11-19 Benzofurankarboksamider og deres terapeutiske anvendelse NO985375D0 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9610515.0A GB9610515D0 (en) 1996-05-20 1996-05-20 Novel compounds
PCT/GB1996/003012 WO1997020833A1 (en) 1995-12-05 1996-12-05 Benzofuran carboxamides and sulphonamides
GBGB9708070.9A GB9708070D0 (en) 1997-04-22 1997-04-22 Compounds
PCT/GB1997/001361 WO1997044337A1 (en) 1996-05-20 1997-05-20 Benzofuran carboxamides and their therapeutic use

Publications (2)

Publication Number Publication Date
NO985375L NO985375L (no) 1998-11-19
NO985375D0 true NO985375D0 (no) 1998-11-19

Family

ID=26309366

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985375A NO985375D0 (no) 1996-05-20 1998-11-19 Benzofurankarboksamider og deres terapeutiske anvendelse

Country Status (19)

Country Link
US (2) US5925636A (hu)
EP (1) EP0901482B1 (hu)
JP (1) JP2000510848A (hu)
CN (1) CN1219171A (hu)
AT (1) ATE239004T1 (hu)
BR (1) BR9709113A (hu)
CA (1) CA2252537A1 (hu)
CZ (1) CZ371998A3 (hu)
DE (1) DE69721526T2 (hu)
ES (1) ES2193376T3 (hu)
HU (1) HUP0100042A3 (hu)
IL (1) IL126558A (hu)
NO (1) NO985375D0 (hu)
NZ (1) NZ332340A (hu)
PL (1) PL329912A1 (hu)
RU (1) RU2162467C2 (hu)
SK (1) SK282676B6 (hu)
TR (1) TR199802386T2 (hu)
WO (1) WO1997044337A1 (hu)

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BR9611897A (pt) * 1995-12-05 1999-12-28 Darwin Discovery Ltd Benzofurano carboxamidas e sulfonamidas
DK0923568T5 (da) * 1996-08-19 2003-11-03 Altana Pharma Ag Hidtil ukendte benzofuran-4-carboxamider
JP4219554B2 (ja) 1997-10-01 2009-02-04 協和発酵キリン株式会社 ベンゾフラン誘導体
AU2529799A (en) * 1998-02-09 1999-08-23 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
ES2196806T3 (es) 1998-05-08 2003-12-16 Smithkline Beecham Plc Derivados de fenilurea y de feniltiourea.
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
US7217722B2 (en) 2000-02-01 2007-05-15 Kirin Beer Kabushiki Kaisha Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
WO2002012189A1 (fr) * 2000-08-09 2002-02-14 Mitsubishi Pharma Corporation Composes amide bicycliques condenses et utilisations medicales associees
US6953774B2 (en) 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation
KR101056916B1 (ko) 2001-12-14 2011-08-12 라보라토리스 세로노 에스.에이. 비폴리펩티드 고리에이엠피 레벨 모듈레이터를 이용한 배란유도 방법
MXPA04009477A (es) * 2002-03-28 2005-01-25 Jun Murakami Derivados de benzofurano.
WO2003090357A1 (en) * 2002-04-19 2003-10-30 Integrated Magnetoelectronics Corporation Interfaces between semiconductor circuitry and transpinnor-based circuitry
ES2195785B1 (es) * 2002-05-16 2005-03-16 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
DE10238257B4 (de) * 2002-08-21 2007-04-19 Johannes-Gutenberg-Universität Mainz Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US20050215626A1 (en) * 2003-09-25 2005-09-29 Wyeth Substituted benzofuran oximes
TW200524915A (en) * 2003-09-26 2005-08-01 Tanabe Seiyaku Co Carbamoyl-type benzofuran derivatives
ES2251866B1 (es) * 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
ES2251867B1 (es) * 2004-06-21 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
US20100130737A1 (en) * 2005-02-18 2010-05-27 Takeda Pharmaceutical Company Limited Regulating Agent of GPR34 Receptor Function
AU2006282896A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス,インコーポレイティド Pde阻害による神経新生の調節
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2027087A2 (en) 2006-05-18 2009-02-25 MannKind Corporation Intracellular kinase inhibitors
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
CN100434426C (zh) * 2006-10-10 2008-11-19 中国科学院昆明植物研究所 盐肤木内酯a,其制备方法和其在制药中的应用
CN101631792B (zh) * 2007-02-28 2013-05-01 利奥制药有限公司 新的磷酸二酯酶抑制剂
DK2114951T3 (da) * 2007-02-28 2014-06-23 Leo Pharma As Hidtil ukendte phosphodiesterase-inhibitorer
ES2320954B1 (es) * 2007-03-02 2010-03-16 Laboratorio Almirall S.A. Nuevo procedimiento de preparacion de 3-metil-4-fenilisoxazolo (3,4-d)iridazin-7(6h)-ona.
KR100752613B1 (ko) * 2007-05-02 2007-08-29 우석대학교 산학협력단 신규 벤조푸란 유도체를 포함하는 부정맥 예방용 식품
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GEP20135793B (en) 2008-09-11 2013-03-25 Pfizer Heteroaryls amide derivatives and their use as glucokinase activators
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DK2406253T3 (da) * 2009-03-11 2013-08-12 Pfizer Benzofuranylderivater anvendt som glucokinase-inhibitorer
RS58945B1 (sr) * 2010-06-24 2019-08-30 Leo Pharma As Derivati benzodioksola kao inhibitori fosfodiesteraze
CN102010405B (zh) * 2010-11-08 2012-07-25 湖南大学 4-(苯并呋喃-5-基)-2-苄亚氨基噻唑及其作为抗肿瘤药物的应用
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
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JPWO2020246418A1 (hu) * 2019-06-04 2020-12-10

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DK0923568T5 (da) * 1996-08-19 2003-11-03 Altana Pharma Ag Hidtil ukendte benzofuran-4-carboxamider

Also Published As

Publication number Publication date
JP2000510848A (ja) 2000-08-22
SK282676B6 (sk) 2002-11-06
EP0901482B1 (en) 2003-05-02
HUP0100042A3 (en) 2003-01-28
US5972936A (en) 1999-10-26
US5925636A (en) 1999-07-20
IL126558A0 (en) 1999-08-17
DE69721526D1 (de) 2003-06-05
SK160498A3 (en) 1999-06-11
RU2162467C2 (ru) 2001-01-27
IL126558A (en) 2002-07-25
CZ371998A3 (cs) 1999-03-17
ES2193376T3 (es) 2003-11-01
NO985375L (no) 1998-11-19
BR9709113A (pt) 1999-08-03
DE69721526T2 (de) 2004-04-08
CA2252537A1 (en) 1997-11-27
CN1219171A (zh) 1999-06-09
ATE239004T1 (de) 2003-05-15
WO1997044337A1 (en) 1997-11-27
HUP0100042A2 (hu) 2002-01-28
EP0901482A1 (en) 1999-03-17
TR199802386T2 (xx) 1999-02-22
NZ332340A (en) 2000-04-28
PL329912A1 (en) 1999-04-26

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