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NO972261L - Hypolipidemiske benzodiazepiner - Google Patents

Hypolipidemiske benzodiazepiner

Info

Publication number
NO972261L
NO972261L NO972261A NO972261A NO972261L NO 972261 L NO972261 L NO 972261L NO 972261 A NO972261 A NO 972261A NO 972261 A NO972261 A NO 972261A NO 972261 L NO972261 L NO 972261L
Authority
NO
Norway
Prior art keywords
hypolipidemic
benzodiazepines
novel
prophylaxis
atherosclerosis
Prior art date
Application number
NO972261A
Other languages
English (en)
Other versions
NO972261D0 (no
NO308470B1 (no
Inventor
Lawrence Edward Brieaddy
Anthony Louis Handlon
Jr Gordon Lewis Hodgson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO972261D0 publication Critical patent/NO972261D0/no
Publication of NO972261L publication Critical patent/NO972261L/no
Publication of NO308470B1 publication Critical patent/NO308470B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Denne oppfinnelse vedrører nye hypolipidemiske forbindelser med formel (I), fremgangsmåter og nye mellomprodukter for deres fremstilling, farmasøytiske blandinger inneholdende dem og deres anvendelse i medisinen, spesielt ved profylakse og behandling av hyperlipidemiske tilstander, og beslektede sykdommer som for eksempel aterosklerose.
NO972261A 1994-11-17 1997-05-16 Hypolipidemiske benzotiazepiner, anvendelse derav, kjemisk forbindelse og farmasøytisk blanding NO308470B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9423172A GB9423172D0 (en) 1994-11-17 1994-11-17 Hypolipidemic benzothiazepines
PCT/GB1995/002700 WO1996016051A1 (en) 1994-11-17 1995-11-16 Hypolipidemic benzothiazepines

Publications (3)

Publication Number Publication Date
NO972261D0 NO972261D0 (no) 1997-05-16
NO972261L true NO972261L (no) 1997-07-16
NO308470B1 NO308470B1 (no) 2000-09-18

Family

ID=10764525

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972261A NO308470B1 (no) 1994-11-17 1997-05-16 Hypolipidemiske benzotiazepiner, anvendelse derav, kjemisk forbindelse og farmasøytisk blanding

Country Status (22)

Country Link
US (1) US5998400A (no)
EP (1) EP0792268B1 (no)
JP (1) JP2868623B2 (no)
KR (1) KR970707111A (no)
CN (1) CN1059674C (no)
AT (1) ATE189891T1 (no)
AU (1) AU706325B2 (no)
BR (1) BR9509683A (no)
CZ (1) CZ147397A3 (no)
DE (1) DE69515183T2 (no)
DK (1) DK0792268T3 (no)
ES (1) ES2144151T3 (no)
FI (1) FI972085L (no)
GB (1) GB9423172D0 (no)
GR (1) GR3033450T3 (no)
HU (1) HUT77412A (no)
MX (1) MX9703546A (no)
NO (1) NO308470B1 (no)
NZ (1) NZ295426A (no)
PL (1) PL320093A1 (no)
PT (1) PT792268E (no)
WO (1) WO1996016051A1 (no)

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Also Published As

Publication number Publication date
AU3876295A (en) 1996-06-17
NO972261D0 (no) 1997-05-16
FI972085A0 (fi) 1997-05-15
EP0792268B1 (en) 2000-02-23
GB9423172D0 (en) 1995-01-04
CN1164230A (zh) 1997-11-05
DE69515183T2 (de) 2000-08-17
PT792268E (pt) 2000-06-30
MX9703546A (es) 1997-08-30
NO308470B1 (no) 2000-09-18
KR970707111A (ko) 1997-12-01
ATE189891T1 (de) 2000-03-15
CN1059674C (zh) 2000-12-20
AU706325B2 (en) 1999-06-17
GR3033450T3 (en) 2000-09-29
DK0792268T3 (da) 2000-07-31
NZ295426A (en) 1997-10-24
EP0792268A1 (en) 1997-09-03
US5998400A (en) 1999-12-07
CZ147397A3 (en) 1997-11-12
DE69515183D1 (de) 2000-03-30
PL320093A1 (en) 1997-09-15
BR9509683A (pt) 1997-09-16
FI972085L (fi) 1997-05-15
WO1996016051A1 (en) 1996-05-30
HUT77412A (hu) 1998-04-28
JPH11500102A (ja) 1999-01-06
ES2144151T3 (es) 2000-06-01
JP2868623B2 (ja) 1999-03-10

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