NO962856D0 - Antisopp Sordaridin-derivater - Google Patents

Antisopp Sordaridin-derivater

Info

Publication number: NO962856D0
Authority: NO; Norway
Prior art keywords: sordaridine; antifungal; derivatives; sordaridine derivatives; antifungal sordaridine
Prior art date: 1994-11-08

Application number

NO962856A

Other languages

English (en)

Other versions

NO962856L (no

NO307092B1 (no

Inventor

Jose Ramon Ruiz Gomez

Jose Maria Bueno Calderon

Silvestre Garcia-Ochoa Dorado

Maria Teresa Fraile Gabaldon

Julia Castro Pichel

Jose Fiandor Roman

Domingo Gargallo Viola

Juan Carlos Cuevas Zurita

Jose Luis Lavandera Diaz

Sophie Huss

Original Assignee

Glaxo Wellcome Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-08

Filing date

1996-07-05

Publication date

1996-07-05

1994-11-08 Priority claimed from EP94500175A external-priority patent/EP0711784A1/en

1994-11-08 Priority claimed from EP94500173A external-priority patent/EP0712859A1/en

1996-07-05 Application filed by Glaxo Wellcome Sa filed Critical Glaxo Wellcome Sa

1996-07-05 Publication of NO962856D0 publication Critical patent/NO962856D0/no

1996-09-05 Publication of NO962856L publication Critical patent/NO962856L/no

2000-02-07 Publication of NO307092B1 publication Critical patent/NO307092B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

NO962856A 1994-11-08 1996-07-05 Sordaridin-derivater, anvendelse derav og farmasoeytisk blanding NO307092B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP94500175A EP0711784A1 (en)	1994-11-08	1994-11-08	Antifungal Sordarin derivatives
EP94500173A EP0712859A1 (en)	1994-11-08	1994-11-08	Antifungal Sordarin derivatives
PCT/EP1995/004331 WO1996014326A1 (en)	1994-11-08	1995-11-06	Antifungal sordaridin derivatives

Publications (3)

Publication Number	Publication Date
NO962856D0 true NO962856D0 (no)	1996-07-05
NO962856L NO962856L (no)	1996-09-05
NO307092B1 NO307092B1 (no)	2000-02-07

Family

ID=26137608

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO962856A NO307092B1 (no)	1994-11-08	1996-07-05	Sordaridin-derivater, anvendelse derav og farmasoeytisk blanding

Country Status (35)

Country	Link
US (2)	US5854280A (no)
EP (1)	EP0753001B1 (no)
JP (1)	JPH09508144A (no)
KR (1)	KR100391401B1 (no)
CN (1)	CN1056849C (no)
AP (1)	AP614A (no)
AR (1)	AR013815A1 (no)
AT (1)	ATE184284T1 (no)
AU (1)	AU704405B2 (no)
BG (1)	BG62620B1 (no)
BR (1)	BR9506473A (no)
CA (1)	CA2179403A1 (no)
CO (1)	CO4520226A1 (no)
CZ (1)	CZ202796A3 (no)
DE (1)	DE69512041T2 (no)
DK (1)	DK0753001T3 (no)
EE (1)	EE9600117A (no)
ES (1)	ES2137549T3 (no)
FI (1)	FI962773L (no)
GR (1)	GR3031677T3 (no)
HK (1)	HK1004222A1 (no)
HU (1)	HU218611B (no)
IL (1)	IL115905A0 (no)
IS (1)	IS4352A (no)
MX (1)	MX9602563A (no)
NO (1)	NO307092B1 (no)
NZ (1)	NZ296091A (no)
OA (1)	OA10303A (no)
PE (1)	PE49696A1 (no)
RU (1)	RU2152398C1 (no)
SI (1)	SI0753001T1 (no)
SK (1)	SK88496A3 (no)
TW (1)	TW321644B (no)
WO (1)	WO1996014326A1 (no)
ZA (1)	ZA959362B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997042195A1 (en) *	1996-05-08	1997-11-13	Glaxo Wellcome S.A.	Process for the preparation of an indacene compound
US6436395B1 (en) *	1996-09-18	2002-08-20	Merck & Co., Inc.	Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control
US6040463A (en) *	1996-10-07	2000-03-21	Merck & Co., Inc.	Sordarin derivatives
US6096511A (en) *	1997-06-10	2000-08-01	Merck & Co., Inc.	Protein elongation factor 2 as a target for antifungal and antiparasitic agents
US5972996A (en) *	1997-08-22	1999-10-26	Merck & Co., Inc.	4-cyano-4-deformylsordarin derivatives
SK2092000A3 (en) *	1997-08-22	2001-02-12	Merck & Co Inc	4-cyano-4-deformylsordarin derivatives, process for the preparation thereof and agricultural agent containing the same and use thereof
US5965612A (en) *	1997-08-22	1999-10-12	Merck & Co., Inc.	4-cyano-4-deformylsordaricin derivatives
US6136853A (en) *	1997-10-03	2000-10-24	Merck & Co., Inc.	Sordarin derivatives
FI974385A0 (fi) *	1997-12-01	1997-12-01	Xyrofin Oy	Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning
US7070965B1 (en) *	1998-04-14	2006-07-04	Zhenhua Yang	Small molecule anticancer compounds and related production process
MA26628A1 (fr) *	1998-05-11	2004-12-20	Glaxo Wellcome Sa	Morpholino ethers
AU760975B2 (en)	1998-10-26	2003-05-22	Merck & Co., Inc.	Microbial transformation product
EP1191948A2 (en)	1999-06-11	2002-04-03	Neorx Corporation	High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en)	1999-07-11	2006-08-22	Neorx Corporation	Skeletal-targeted radiation to treat bone-associated pathologies
EP1228049A1 (en)	1999-11-11	2002-08-07	Glaxo Wellcome S.A.	Antifungal sordaricin derivatives
US20040176391A1 (en) *	2002-12-31	2004-09-09	Nektar Therapeutics	Aerosolizable pharmaceutical formulation for fungal infection therapy
AU2001289063A1 (en) *	2000-09-15	2002-03-26	Bristol-Myers Squibb Company	Novel thio derivatives of sordarin as antifungal agents
AU2002249935A1 (en)	2001-01-08	2002-08-19	Neorx Corporation	Radioactively labelled conjugates of phosphonates
WO2003007878A2 (en)	2001-07-18	2003-01-30	Merck & Co., Inc.	Antifungal agents of sordarin derivatives
EP1458416A1 (en)	2001-12-13	2004-09-22	Dow Global Technologies Inc.	Treatment of osteomyelitis with radiopharmaceuticals
EP1458725B1 (en) *	2001-12-14	2007-02-21	Merck & Co., Inc.	A novel sordarin derivative isolated from culture fermentations and functions as an antifungal agent
US9314524B2 (en)	2007-12-31	2016-04-19	Calla Therapeutics Llc	Topical formulations of Flucytosine
US8419948B2 (en) *	2009-11-22	2013-04-16	United Laboratories International, Llc	Wastewater treatment
WO2012033427A1 (ru) *	2010-09-08	2012-03-15	Dalin Mikhail Viktorovich	Способ лечения микотических инфекций и препарат для его осуществления
RU2630403C2 (ru) *	2016-02-25	2017-09-07	Жанна Владимировна Вараткова	Абразивная масса для изготовления инструмента с высокими номерами структуры

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH465771A (de) *	1965-12-06	1968-11-30	Sandoz Ag	Verfahren zur Herstellung eines neuen Antibioticums
JPH0615555B2 (ja) *	1985-08-14	1994-03-02	三共株式会社	抗生物質ゾフイマリン
JP3189443B2 (ja) *	1992-11-20	2001-07-16	萬有製薬株式会社	抗真菌性物質ｂｅ−３１４０５
ES2203819T3 (es) *	1996-09-12	2004-04-16	MERCK & CO., INC.	Terapia antifungica combinada.

1995
- 1995-11-06 SK SK884-96A patent/SK88496A3/sk unknown
- 1995-11-06 EP EP95938406A patent/EP0753001B1/en not_active Expired - Lifetime
- 1995-11-06 ZA ZA959362A patent/ZA959362B/xx unknown
- 1995-11-06 RU RU96115273/04A patent/RU2152398C1/ru active
- 1995-11-06 AP APAP/P/1996/000824A patent/AP614A/en active
- 1995-11-06 CZ CZ962027A patent/CZ202796A3/cs unknown
- 1995-11-06 BR BR9506473A patent/BR9506473A/pt not_active IP Right Cessation
- 1995-11-06 SI SI9530311T patent/SI0753001T1/xx not_active IP Right Cessation
- 1995-11-06 CA CA002179403A patent/CA2179403A1/en not_active Abandoned
- 1995-11-06 PE PE1995283875A patent/PE49696A1/es not_active Application Discontinuation
- 1995-11-06 EE EE9600117A patent/EE9600117A/xx unknown
- 1995-11-06 MX MX9602563A patent/MX9602563A/es not_active IP Right Cessation
- 1995-11-06 DE DE69512041T patent/DE69512041T2/de not_active Expired - Fee Related
- 1995-11-06 NZ NZ296091A patent/NZ296091A/en unknown
- 1995-11-06 KR KR1019960703661A patent/KR100391401B1/ko not_active IP Right Cessation
- 1995-11-06 ES ES95938406T patent/ES2137549T3/es not_active Expired - Lifetime
- 1995-11-06 US US08/669,441 patent/US5854280A/en not_active Expired - Fee Related
- 1995-11-06 DK DK95938406T patent/DK0753001T3/da active
- 1995-11-06 AT AT95938406T patent/ATE184284T1/de not_active IP Right Cessation
- 1995-11-06 CN CN95192028A patent/CN1056849C/zh not_active Expired - Fee Related
- 1995-11-06 HU HU9701865A patent/HU218611B/hu not_active IP Right Cessation
- 1995-11-06 WO PCT/EP1995/004331 patent/WO1996014326A1/en not_active Application Discontinuation
- 1995-11-06 AU AU39809/95A patent/AU704405B2/en not_active Ceased
- 1995-11-06 JP JP8515051A patent/JPH09508144A/ja not_active Ceased
- 1995-11-07 AR ARP950100073A patent/AR013815A1/es unknown
- 1995-11-07 CO CO95052481A patent/CO4520226A1/es unknown
- 1995-11-07 IL IL11590595A patent/IL115905A0/xx unknown
- 1995-11-18 TW TW084112259A patent/TW321644B/zh active
1996
- 1996-06-10 IS IS4352A patent/IS4352A/is unknown
- 1996-07-03 OA OA60855A patent/OA10303A/en unknown
- 1996-07-05 NO NO962856A patent/NO307092B1/no not_active IP Right Cessation
- 1996-07-05 FI FI962773A patent/FI962773L/fi not_active IP Right Cessation
- 1996-07-05 BG BG100699A patent/BG62620B1/xx unknown
1998
- 1998-04-21 HK HK98103335A patent/HK1004222A1/xx not_active IP Right Cessation
- 1998-05-19 US US09/081,090 patent/US5952334A/en not_active Expired - Fee Related
1999
- 1999-10-27 GR GR990402767T patent/GR3031677T3/el unknown

Also Published As

Publication number	Publication date
BG100699A (bg)	1997-02-28
HUT76292A (en)	1997-07-28
DE69512041T2 (de)	2000-02-03
HK1004222A1 (en)	1998-11-20
MX9602563A (es)	1997-05-31
NZ296091A (en)	1998-06-26
WO1996014326A1 (en)	1996-05-17
AU3980995A (en)	1996-05-31
EP0753001B1 (en)	1999-09-08
BG62620B1 (en)	2000-03-31
AR013815A1 (es)	2001-01-31
RU2152398C1 (ru)	2000-07-10
US5854280A (en)	1998-12-29
GR3031677T3 (en)	2000-02-29
AU704405B2 (en)	1999-04-22
AP9600824A0 (en)	1996-07-31
CN1143965A (zh)	1997-02-26
ATE184284T1 (de)	1999-09-15
CA2179403A1 (en)	1996-05-17
IS4352A (is)	1996-06-10
FI962773A0 (fi)	1996-07-05
IL115905A0 (en)	1996-01-31
BR9506473A (pt)	1997-10-07
HU9601865D0 (en)	1996-11-28
HU218611B (hu)	2000-10-28
EE9600117A (et)	1997-04-15
SI0753001T1 (en)	1999-12-31
KR100391401B1 (ko)	2003-12-31
ES2137549T3 (es)	1999-12-16
OA10303A (en)	1997-10-07
CO4520226A1 (es)	1997-10-15
NO962856L (no)	1996-09-05
EP0753001A1 (en)	1997-01-15
DE69512041D1 (de)	1999-10-14
CN1056849C (zh)	2000-09-27
NO307092B1 (no)	2000-02-07
CZ202796A3 (en)	1997-02-12
ZA959362B (en)	1996-05-08
JPH09508144A (ja)	1997-08-19
AP614A (en)	1997-09-05
PE49696A1 (es)	1996-12-05
FI962773L (fi)	1996-08-26
TW321644B (no)	1997-12-01
US5952334A (en)	1999-09-14
SK88496A3 (en)	1997-04-09
DK0753001T3 (da)	2000-05-08

Publication	Publication Date	Title
NO304430B1 (no)	1998-12-14	Antifungale midler
FI954829L (fi)	1996-04-15	Aroyylipiperidiinijohdannaiset
NO952854D0 (no)	1995-07-18	1-arylpyrimidin-derivater
DE59508427D1 (de)	2000-07-06	3-aryl-4-hydroxy-delta 3 -dihydrothiophenon-derivate
DE69512041D1 (de)	1999-10-14	Antifungale sordaridin-derivate
ATA147195A (de)	1996-08-15	Alkoxyphenyl-substituierte bisbenzoylphosphinoxide
ATA163695A (de)	1999-01-15	2-hydroxyphenyltriazine
EP0708091A3 (en)	1996-07-17	Indoloyl-guanidines derivatives
DE69430587D1 (de)	2002-06-13	Pyrimidin-acyclonukleosid-derivate
BR9509793A (pt)	1997-09-30	Derivados de tiofeneno
FI971227L (fi)	1997-05-23	Pyramidinyylipyratsolijohdannaisia
FI973812L (fi)	1997-11-11	Antifungaalisia koostumuksia
FI960367L (fi)	1996-01-26	Uusia dialkoksipyridinyylibentsimidatsolijohdannaisia
FI950710A0 (fi)	1995-02-16	Fungisidisia 2-imidatsoliini-5-onejohdannaisia
DE69527786D1 (de)	2002-09-19	Diaminomethyliden-derivate
FI964853L (fi)	1997-02-07	Deasetoksitaksolijohdannaiset
ATA108995A (de)	2005-07-15	Differenzdruckakkumulator
KR950033309U (ko)	1995-12-16	줄연장
DE59509209D1 (de)	2001-05-23	Diphenyloxazolin-derivate
FI955026L (fi)	1996-04-23	Alkyyli-5-metyylisulfonyylibentsoyyliguanidiinijohdannaisia
NO970144L (no)	1997-01-20	Trifluormetylkinolinkarboksylsyre-derivat
DE69510792D1 (de)	1999-08-19	Naphtochinonderivate
BR9509877A (pt)	1997-09-30	Novos derivados de pirimidinilóxi-e piridimidinilamino- etilfenil-dioxolano
FI963122L (fi)	1996-08-09	Karbamoyylimetyyliureajohdannaiset
BR9506613A (pt)	1997-09-16	Derivados de feniltio-oxazolinas

Legal Events

Date	Code	Title	Description
2002-07-08	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MAY 2002