FI954829L - Aroyylipiperidiinijohdannaiset - Google Patents

Aroyylipiperidiinijohdannaiset Download PDF

Info

Publication number: FI954829L
Authority: FI; Finland
Prior art keywords: aroylpiperidine; derivatives; aroylpiperidine derivatives
Prior art date: 1994-10-14

Application number

FI954829A

Other languages

English (en)

Swedish (sv)

Other versions

FI954829A0 (fi

FI114795B (fi

Inventor

Silvio Ofner

Siem Jacob Veenstra

Walter Schilling

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-14

Filing date

1995-10-11

Publication date

1996-04-15

1995-10-11 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1995-10-11 Publication of FI954829A0 publication Critical patent/FI954829A0/fi

1996-04-15 Publication of FI954829L publication Critical patent/FI954829L/fi

2004-12-31 Application granted granted Critical

2004-12-31 Publication of FI114795B publication Critical patent/FI114795B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

FI954829A 1994-10-14 1995-10-11 Aroyylipiperidiinijohdannaiset FI114795B (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH309194		1994-10-14
CH309194		1994-10-14

Publications (3)

Publication Number	Publication Date
FI954829A0 FI954829A0 (fi)	1995-10-11
FI954829L true FI954829L (fi)	1996-04-15
FI114795B FI114795B (fi)	2004-12-31

Family

ID=4248427

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI954829A FI114795B (fi)	1994-10-14	1995-10-11	Aroyylipiperidiinijohdannaiset

Country Status (23)

Country	Link
US (1)	US5965562A (fi)
EP (1)	EP0707006B1 (fi)
JP (1)	JP3022951B2 (fi)
KR (1)	KR100413985B1 (fi)
CN (1)	CN1066445C (fi)
AT (1)	ATE178602T1 (fi)
AU (1)	AU705851B2 (fi)
CA (1)	CA2160444C (fi)
DE (1)	DE59505575D1 (fi)
DK (1)	DK0707006T3 (fi)
ES (1)	ES2132580T3 (fi)
FI (1)	FI114795B (fi)
GR (1)	GR3030515T3 (fi)
HU (1)	HUT74103A (fi)
IL (1)	IL115572A (fi)
MX (1)	MX9504349A (fi)
MY (1)	MY114679A (fi)
NO (1)	NO308034B1 (fi)
NZ (1)	NZ280212A (fi)
RU (1)	RU2158731C2 (fi)
SA (1)	SA96160637B1 (fi)
TW (1)	TW397825B (fi)
ZA (1)	ZA958647B (fi)

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TW397825B (en) *	1994-10-14	2000-07-11	Novartis Ag	Aroyl-piperidine derivatives
RU2156250C2 (ru) *	1995-04-24	2000-09-20	Новартис Аг	Производные хромона, способ их получения и фармацевтическая композиция
WO1997045119A1 (en) *	1996-05-24	1997-12-04	Novartis Ag	Use of substance p antagonists for treating social phobia
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ES2198948T3 (es) *	1998-08-25	2004-02-01	Novartis Ag	Usos de antagonistas de la substancia p para el tratamiento del sindrome de la fatiga cronica y/o de la fibromialgia.
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DK1246806T3 (da)	1999-11-03	2008-06-16	Amr Technology Inc	Aryl- og heteroarylsubstituerede tetrahydroisoquinoliner og anvendelse deraf til blokering af genoptagelse af norepinefrin, dopsmin og serotonin
US7163949B1 (en)	1999-11-03	2007-01-16	Amr Technology, Inc.	4-phenyl substituted tetrahydroisoquinolines and use thereof
JP2001294582A (ja) *	2000-04-12	2001-10-23	Fuji Chemical Industries Ltd	光学活性アミノブチロラクトンの製造法
WO2002004455A2 (en)	2000-07-11	2002-01-17	Albany Molecular Research, Inc	4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
SI1474395T1 (sl) *	2002-02-12	2008-02-29	Smithkline Beecham Corp	Nikotinamidni derivati, uporabni kot inhibitorji p38
GB0220953D0 (en)	2002-09-10	2002-10-23	Novartis Ag	Organic compounds
GB2394417A (en) *	2002-10-24	2004-04-28	Novartis Ag	Solid dispersion comprising a piperidine substance P antagonist and a carrier
BRPI0409211A (pt)	2003-04-18	2006-03-28	Lilly Co Eli	composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto
KR101389246B1 (ko)	2004-07-15	2014-04-24	브리스톨-마이어스스퀴브컴파니	아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및 이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
US8362075B2 (en)	2005-05-17	2013-01-29	Merck Sharp & Dohme Corp.	Cyclohexyl sulphones for treatment of cancer
NZ565111A (en)	2005-07-15	2011-10-28	Amr Technology Inc	Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
GB0603041D0 (en)	2006-02-15	2006-03-29	Angeletti P Ist Richerche Bio	Therapeutic compounds
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
CA2674436C (en)	2007-01-10	2012-07-17	Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A.	Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
EP2170076B1 (en)	2007-06-27	2016-05-18	Merck Sharp & Dohme Corp.	4-carboxybenzylamino derivatives as histone deacetylase inhibitors
AR071997A1 (es)	2008-06-04	2010-07-28	Bristol Myers Squibb Co	Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
US8691825B2 (en)	2009-04-01	2014-04-08	Merck Sharp & Dohme Corp.	Inhibitors of AKT activity
AU2010247763B2 (en)	2009-05-12	2015-12-24	Albany Molecular Research, Inc.	7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
ES2446971T3 (es)	2009-05-12	2014-03-11	Albany Molecular Research, Inc.	Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
ES2528404T3 (es)	2009-05-12	2015-02-10	Bristol-Myers Squibb Company	Formas cristalinas de (S)-7-([1,2,4]triazol[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y sus usos
US8859776B2 (en)	2009-10-14	2014-10-14	Merck Sharp & Dohme Corp.	Substituted piperidines that increase p53 activity and the uses thereof
CA2805265A1 (en)	2010-08-02	2012-02-09	Merck Sharp & Dohme Corp.	Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
HRP20191232T1 (hr)	2010-08-17	2019-11-01	Sirna Therapeutics Inc	Inhibicija, posredovana rna interferencijom, ekspresije gena virusa hepatitisa b (hbv) korištenjem kratkih interferirajućih nukleinskih kiselina (sina)
EP2608669B1 (en)	2010-08-23	2016-06-22	Merck Sharp & Dohme Corp.	NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
US8946216B2 (en)	2010-09-01	2015-02-03	Merck Sharp & Dohme Corp.	Indazole derivatives useful as ERK inhibitors
US9242981B2 (en)	2010-09-16	2016-01-26	Merck Sharp & Dohme Corp.	Fused pyrazole derivatives as novel ERK inhibitors
DK2632472T3 (en)	2010-10-29	2018-03-19	Sirna Therapeutics Inc	RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
EP2654748B1 (en)	2010-12-21	2016-07-27	Merck Sharp & Dohme Corp.	Indazole derivatives useful as erk inhibitors
AU2012245455A1 (en)	2011-04-21	2013-10-31	Merck Sharp & Dohme Corp.	Insulin-Like Growth Factor-1 Receptor inhibitors
EP2770987B1 (en)	2011-10-27	2018-04-04	Merck Sharp & Dohme Corp.	Novel compounds that are erk inhibitors
EP2844261B1 (en)	2012-05-02	2018-10-17	Sirna Therapeutics, Inc.	SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
JP6280554B2 (ja)	2012-09-28	2018-02-14	メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋＳｈａｒｐ＆ＤｏｈｍｅＣｏｒｐ．	Ｅｒｋ阻害剤である新規化合物
AU2013352568B2 (en)	2012-11-28	2019-09-19	Merck Sharp & Dohme Llc	Compositions and methods for treating cancer
KR102196882B1 (ko)	2012-12-20	2020-12-30	머크 샤프 앤드 돔 코포레이션	Hdm2 억제제로서의 치환된 이미다조피리딘
US9540377B2 (en)	2013-01-30	2017-01-10	Merck Sharp & Dohme Corp.	2,6,7,8 substituted purines as HDM2 inhibitors
US20160194368A1 (en)	2013-09-03	2016-07-07	Moderna Therapeutics, Inc.	Circular polynucleotides
US10975084B2 (en)	2016-10-12	2021-04-13	Merck Sharp & Dohme Corp.	KDM5 inhibitors
WO2019094311A1 (en)	2017-11-08	2019-05-16	Merck Sharp & Dohme Corp.	Prmt5 inhibitors
WO2019094312A1 (en)	2017-11-08	2019-05-16	Merck Sharp & Dohme Corp.	Prmt5 inhibitors
CN112805006B (zh)	2018-08-07	2024-09-24	默沙东有限责任公司	Prmt5抑制剂
EP3833667B1 (en)	2018-08-07	2024-03-13	Merck Sharp & Dohme LLC	Prmt5 inhibitors
EP3833668B1 (en)	2018-08-07	2025-03-19	Merck Sharp & Dohme LLC	Prmt5 inhibitors
CN111808017B (zh) *	2020-08-05	2023-11-28	国家纳米科学中心	一种含氮杂环化合物及其制备方法和应用

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SU1593569A3 (ru) *	1982-07-30	1990-09-15	Janssen Pharmaceutica Nv	Cпocoб пoлучehия пpoизboдhыx n-(3-гидpokcи-4-пипepидиhил)бehзamидa или иx kиcлotho-aддиtиbhыx coлeй
DK386089A (da) *	1988-08-12	1990-02-13	Japan Tobacco Inc	Katekolderivater
MX18467A (es) *	1988-11-23	1993-07-01	Pfizer	Agentes terapeuticos de quinuclidinas
US5145967A (en) *	1989-04-20	1992-09-08	Anaquest, Inc.	Method for preparing 4-alkoxyalkyl-4-phenylaminopiperdines and derivatives thereof
IE903957A1 (en) *	1989-11-06	1991-05-08	Sanofi Sa	Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
FR2654725B1 (fr) *	1989-11-23	1992-02-14	Rhone Poulenc Sante	Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
US5126455A (en) *	1989-12-13	1992-06-30	Glaxo Inc.	Preparation of substituted alkali metal piperidine-4-carboxylates
FR2659323B1 (fr) *	1990-03-07	1992-06-12	Synthelabo	Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique.
PL168236B1 (pl) *	1990-05-31	1996-01-31	Pfizer	Sposób wytwarzania podstawionych piperydyn PL PL PL
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MY110227A (en) *	1991-08-12	1998-03-31	Ciba Geigy Ag	1-acylpiperindine compounds.
TW397825B (en) *	1994-10-14	2000-07-11	Novartis Ag	Aroyl-piperidine derivatives

1995
- 1995-10-02 TW TW084110255A patent/TW397825B/zh not_active IP Right Cessation
- 1995-10-05 AT AT95810628T patent/ATE178602T1/de active
- 1995-10-05 ES ES95810628T patent/ES2132580T3/es not_active Expired - Lifetime
- 1995-10-05 DK DK95810628T patent/DK0707006T3/da active
- 1995-10-05 EP EP95810628A patent/EP0707006B1/de not_active Expired - Lifetime
- 1995-10-05 DE DE59505575T patent/DE59505575D1/de not_active Expired - Lifetime
- 1995-10-10 AU AU33174/95A patent/AU705851B2/en not_active Ceased
- 1995-10-10 MY MYPI95003026A patent/MY114679A/en unknown
- 1995-10-11 FI FI954829A patent/FI114795B/fi not_active IP Right Cessation
- 1995-10-11 IL IL11557295A patent/IL115572A/en not_active IP Right Cessation
- 1995-10-12 NZ NZ280212A patent/NZ280212A/en not_active IP Right Cessation
- 1995-10-12 CA CA002160444A patent/CA2160444C/en not_active Expired - Fee Related
- 1995-10-13 JP JP7265610A patent/JP3022951B2/ja not_active Expired - Fee Related
- 1995-10-13 NO NO954067A patent/NO308034B1/no not_active IP Right Cessation
- 1995-10-13 CN CN95116776A patent/CN1066445C/zh not_active Expired - Fee Related
- 1995-10-13 KR KR1019950035296A patent/KR100413985B1/ko not_active Expired - Fee Related
- 1995-10-13 ZA ZA958647A patent/ZA958647B/xx unknown
- 1995-10-13 HU HU9502973A patent/HUT74103A/hu not_active Application Discontinuation
- 1995-10-13 RU RU95117719/04A patent/RU2158731C2/ru not_active IP Right Cessation
- 1995-10-13 MX MX9504349A patent/MX9504349A/es unknown
1996
- 1996-03-02 SA SA96160637A patent/SA96160637B1/ar unknown
1997
- 1997-10-30 US US08/961,546 patent/US5965562A/en not_active Expired - Fee Related
1999
- 1999-06-15 GR GR990401590T patent/GR3030515T3/el unknown

Also Published As

Publication number	Publication date
HUT74103A (en)	1996-11-28
KR100413985B1 (ko)	2004-03-26
AU705851B2 (en)	1999-06-03
IL115572A (en)	2001-05-20
NO954067D0 (no)	1995-10-13
JP3022951B2 (ja)	2000-03-21
AU3317495A (en)	1996-04-26
FI954829A0 (fi)	1995-10-11
FI114795B (fi)	2004-12-31
CN1066445C (zh)	2001-05-30
IL115572A0 (en)	1996-01-19
ZA958647B (en)	1996-04-15
NO308034B1 (no)	2000-07-10
EP0707006B1 (de)	1999-04-07
EP0707006A1 (de)	1996-04-17
ATE178602T1 (de)	1999-04-15
DK0707006T3 (da)	1999-10-18
RU2158731C2 (ru)	2000-11-10
JPH08176145A (ja)	1996-07-09
CA2160444A1 (en)	1996-04-15
US5965562A (en)	1999-10-12
NZ280212A (en)	2001-10-26
MY114679A (en)	2002-12-31
ES2132580T3 (es)	1999-08-16
DE59505575D1 (de)	1999-05-12
TW397825B (en)	2000-07-11
NO954067L (no)	1996-04-15
GR3030515T3 (en)	1999-10-29
CN1133839A (zh)	1996-10-23
MX9504349A (es)	1997-03-29
KR960014121A (ko)	1996-05-22
SA96160637B1 (ar)	2005-06-14
CA2160444C (en)	2006-11-28
HU9502973D0 (en)	1995-12-28

Publication	Publication Date	Title
FI954829L (fi)	1996-04-15	Aroyylipiperidiinijohdannaiset
NO952854D0 (no)	1995-07-18	1-arylpyrimidin-derivater
DE59508427D1 (de)	2000-07-06	3-aryl-4-hydroxy-delta 3 -dihydrothiophenon-derivate
DK0901474T3 (da)	2006-07-31	Arylpyrimidinderivater
DK0891332T3 (da)	2004-07-05	6-phenylpyridyl-2-aminderivater
NO981946D0 (no)	1998-04-29	Imidazoquinazolin-derivater
EP0708091A3 (en)	1996-07-17	Indoloyl-guanidines derivatives
DE69732576D1 (de)	2005-03-31	Tetrahydrobenzindolon-derivate
DE69430587D1 (de)	2002-06-13	Pyrimidin-acyclonukleosid-derivate
BR9509793A (pt)	1997-09-30	Derivados de tiofeneno
FI971227A7 (fi)	1997-05-23	Pyramidinyylipyratsolijohdannaisia
FI960367A7 (fi)	1996-01-26	Uusia dialkoksipyridinyylibentsimidatsolijohdannaisia
IS5026A (is)	1999-04-15	2-metoxýfenýlpíperasín afleiður
DE69527786D1 (de)	2002-09-19	Diaminomethyliden-derivate
FI964853L (fi)	1997-02-07	Deasetoksitaksolijohdannaiset
NO970144D0 (no)	1997-01-14	Trifluormetylkinolinkarboksylsyre-derivat
DE69510792D1 (de)	1999-08-19	Naphtochinonderivate
DE59509209D1 (de)	2001-05-23	Diphenyloxazolin-derivate
FI955026L (fi)	1996-04-23	Alkyyli-5-metyylisulfonyylibentsoyyliguanidiinijohdannaisia
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1997-08-12	GB	Transfer or assigment of application	Owner name: NOVARTIS AG
2012-06-11	MM	Patent lapsed