NO951181D0 - Immunogen menigokokk-LPS, ytter-membranvesikler, samt vaksine fremstilt derav - Google Patents
Immunogen menigokokk-LPS, ytter-membranvesikler, samt vaksine fremstilt deravInfo
- Publication number
- NO951181D0 NO951181D0 NO951181A NO951181A NO951181D0 NO 951181 D0 NO951181 D0 NO 951181D0 NO 951181 A NO951181 A NO 951181A NO 951181 A NO951181 A NO 951181A NO 951181 D0 NO951181 D0 NO 951181D0
- Authority
- NO
- Norway
- Prior art keywords
- outer membrane
- omp
- pct
- lipopolysaccharide
- directed
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 7
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title 1
- 239000002158 endotoxin Substances 0.000 abstract 5
- 229920006008 lipopolysaccharide Polymers 0.000 abstract 5
- 230000003213 activating effect Effects 0.000 abstract 2
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 101710116435 Outer membrane protein Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 229930182830 galactose Natural products 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000036046 immunoreaction Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 150000002482 oligosaccharides Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9201716A NL9201716A (nl) | 1992-10-02 | 1992-10-02 | Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. |
PCT/NL1993/000163 WO1994008021A1 (en) | 1992-10-02 | 1993-07-30 | Immunogenic meningococcal lps and outer membrane vesicles and vaccine therefrom |
Publications (3)
Publication Number | Publication Date |
---|---|
NO951181D0 true NO951181D0 (no) | 1995-03-28 |
NO951181L NO951181L (no) | 1995-06-01 |
NO321651B1 NO321651B1 (no) | 2006-06-19 |
Family
ID=19861338
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19951181A NO321651B1 (no) | 1992-10-02 | 1995-03-28 | Immunogent meningokokk-lipopoly-sakkarid, ytter-membranvesikler, samt vaksine fremstilt derav. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5705161A (no) |
EP (1) | EP0680512B1 (no) |
JP (1) | JPH08501940A (no) |
AT (1) | ATE364702T1 (no) |
AU (1) | AU684720B2 (no) |
CA (1) | CA2146145C (no) |
DE (1) | DE69334147T2 (no) |
DK (1) | DK0680512T3 (no) |
ES (1) | ES2289739T3 (no) |
FI (1) | FI951535L (no) |
NL (1) | NL9201716A (no) |
NO (1) | NO321651B1 (no) |
PT (1) | PT680512E (no) |
WO (1) | WO1994008021A1 (no) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7118757B1 (en) * | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
AU707131B2 (en) * | 1995-08-04 | 1999-07-01 | University Of Guelph | Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same |
US20020028215A1 (en) | 1999-08-09 | 2002-03-07 | Jagath L. Kadurugamuwa | Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same |
US6872398B2 (en) * | 1995-12-22 | 2005-03-29 | The United States Of America As Represented By The Secretary Of The Army | Conjugate vaccine against gram-negative bacterial infections |
US6645503B1 (en) * | 1998-03-10 | 2003-11-11 | Wyeth Holdings Corporation | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria |
US10967045B2 (en) | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
US6514948B1 (en) * | 1999-07-02 | 2003-02-04 | The Regents Of The University Of California | Method for enhancing an immune response |
US6531131B1 (en) | 1999-08-10 | 2003-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for Neisseria meningitidis |
US7585510B1 (en) | 1999-09-30 | 2009-09-08 | Isis Innovation Limited | Vaccine |
AU2001280883A1 (en) * | 2000-07-27 | 2002-02-13 | The Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
CA2479879A1 (en) * | 2002-03-20 | 2003-10-02 | Emory University | Neisseria mutants, lipooligosaccharides and immunogenic compositions |
MY149591A (en) | 2002-08-02 | 2013-09-13 | Glaxosmithkline Biolog Sa | Vaccines comprising l2 and/or l3 los from neisseria |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
SI2351579T1 (sl) | 2002-10-11 | 2017-05-31 | Glaxosmithkline Biologicals Sa | Polipeptidna cepiva za široko zaščito proti hipervirulentnim meningokoknim linijam |
ATE466875T1 (de) | 2002-11-15 | 2010-05-15 | Novartis Vaccines & Diagnostic | Unerwartete oberflächenproteine in neisseria meningitidis |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
CA2514328C (en) | 2003-01-30 | 2020-01-14 | Chiron Srl | Injectable vaccines against multiple meningococcal serogroups |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
US7537766B2 (en) * | 2004-08-30 | 2009-05-26 | Wyeth | Neisseria meningitidis inner core lipo-oligosaccharide epitopes, multivalent conjugates thereof and immunogenic compositions thereof |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
NZ555937A (en) | 2005-01-27 | 2009-05-31 | Childrens Hosp & Res Ct Oak | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
US20090246224A1 (en) | 2006-06-12 | 2009-10-01 | Nathalie Devos | Vaccine |
WO2009104097A2 (en) | 2008-02-21 | 2009-08-27 | Novartis Ag | Meningococcal fhbp polypeptides |
MX2010012999A (es) * | 2008-05-30 | 2012-03-07 | U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army | Vacuna de vesícula de membrana externa nativa multivalente del meningococo, método para su fabricación y uso. |
CA2756533A1 (en) | 2009-03-24 | 2010-09-30 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
HUE049695T2 (hu) | 2009-03-24 | 2020-10-28 | Glaxosmithkline Biologicals Sa | Adjuváló H meningococcus faktort kötõ fehérje |
AU2010247254A1 (en) * | 2009-05-14 | 2012-01-12 | Sanofi Pasteur | Menigococcus vaccine containing lipooligosaccharide (LOS) from modified strains of L6 immunotype Neisseria meningitidis |
JP5536765B2 (ja) * | 2009-05-20 | 2014-07-02 | 国立大学法人鳥取大学 | 部分糖鎖エピトープを用いた、病原性ナイセリア属細菌感染の検出方法およびそれら細菌に対するワクチン |
US20110076300A1 (en) | 2009-08-27 | 2011-03-31 | Mariagrazia Pizza | Hybrid Polypeptides Including Meningococcal fHBP Sequences |
CN102740882A (zh) | 2009-08-27 | 2012-10-17 | 诺华有限公司 | 含有铝、寡核苷酸和聚阳离子的佐剂 |
AU2010302344A1 (en) | 2009-09-30 | 2012-04-26 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
JP5960055B2 (ja) | 2009-10-27 | 2016-08-02 | ノバルティス アーゲー | 改変髄膜炎菌fHBPポリペプチド |
EP2547357A1 (en) | 2010-03-18 | 2013-01-23 | Novartis AG | Adjuvanted vaccines for serogroup b meningococcus |
US10478483B2 (en) | 2010-06-25 | 2019-11-19 | Glaxosmithkline Biologicals Sa | Combinations of meningococcal factor H binding proteins |
BR112014016223A8 (pt) | 2011-12-29 | 2017-07-04 | Novartis Ag | combinações adjuvantes de proteínas de ligação de fator h meningocócico |
KR20160127104A (ko) | 2014-02-28 | 2016-11-02 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 변형된 수막구균 fhbp 폴리펩티드 |
GB201712824D0 (en) | 2017-08-10 | 2017-09-27 | Glaxosmithkline Biologicals Sa | Multi-functionalized nOMV Conjugates |
JP2021533834A (ja) * | 2018-08-14 | 2021-12-09 | エバーサイト・ゲーエムベーハー | 標的特異的細胞外小胞 |
EP4277654A1 (en) | 2021-01-18 | 2023-11-22 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990006696A2 (en) * | 1988-12-19 | 1990-06-28 | Praxis Biologics, Inc. | Meningococcal class 1 outer-membrane protein vaccine |
NL9101359A (nl) * | 1991-08-07 | 1993-03-01 | Nederlanden Staat | Nieuw saccharide-peptide-conjugaat, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk saccharide-peptide-conjugaat omvat. |
-
1992
- 1992-10-02 NL NL9201716A patent/NL9201716A/nl not_active Application Discontinuation
-
1993
- 1993-07-30 CA CA002146145A patent/CA2146145C/en not_active Expired - Lifetime
- 1993-07-30 EP EP93921120A patent/EP0680512B1/en not_active Expired - Lifetime
- 1993-07-30 DK DK93921120T patent/DK0680512T3/da active
- 1993-07-30 JP JP6508917A patent/JPH08501940A/ja active Pending
- 1993-07-30 AU AU48351/93A patent/AU684720B2/en not_active Ceased
- 1993-07-30 AT AT93921120T patent/ATE364702T1/de active
- 1993-07-30 DE DE69334147T patent/DE69334147T2/de not_active Expired - Lifetime
- 1993-07-30 US US08/411,727 patent/US5705161A/en not_active Expired - Lifetime
- 1993-07-30 WO PCT/NL1993/000163 patent/WO1994008021A1/en active IP Right Grant
- 1993-07-30 ES ES93921120T patent/ES2289739T3/es not_active Expired - Lifetime
- 1993-07-30 PT PT93921120T patent/PT680512E/pt unknown
-
1995
- 1995-03-28 NO NO19951181A patent/NO321651B1/no not_active IP Right Cessation
- 1995-03-31 FI FI951535A patent/FI951535L/fi unknown
Also Published As
Publication number | Publication date |
---|---|
WO1994008021A1 (en) | 1994-04-14 |
DE69334147D1 (de) | 2007-07-26 |
NO321651B1 (no) | 2006-06-19 |
AU684720B2 (en) | 1998-01-08 |
NL9201716A (nl) | 1994-05-02 |
JPH08501940A (ja) | 1996-03-05 |
ATE364702T1 (de) | 2007-07-15 |
CA2146145A1 (en) | 1994-04-14 |
FI951535A0 (fi) | 1995-03-31 |
NO951181L (no) | 1995-06-01 |
PT680512E (pt) | 2007-09-25 |
EP0680512A1 (en) | 1995-11-08 |
ES2289739T3 (es) | 2008-02-01 |
CA2146145C (en) | 2009-10-27 |
AU4835193A (en) | 1994-04-26 |
DE69334147T2 (de) | 2008-02-14 |
FI951535L (fi) | 1995-06-01 |
DK0680512T3 (da) | 2007-10-01 |
US5705161A (en) | 1998-01-06 |
EP0680512B1 (en) | 2007-06-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO951181L (no) | Immunogen menigokokk-LPS, ytter-membranvesikler, samt vaksine fremstilt derav | |
WO1990006696A3 (en) | Meningococcal class 1 outer-membrane protein vaccine | |
Wetzler et al. | Gonococcal porin vaccine evaluation: comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants | |
NO943739L (no) | Vaksiner inneholdende vesikler basert på ikke-ioniske overflate-aktive midler | |
AU657487B2 (en) | Nucleotide sequence coding for an outer membrane protein from neisseria meningitidis and use of said protein in vaccine preparations | |
ATE252602T1 (de) | Meningokokkus b-epitop ausbildende monoklonale antikoerper und deren verwendung zur herstellung von impfstoffzusammenstellungen | |
WO1996029605A3 (en) | Compounds and methods for the dectection of t. cruzi infection | |
KR900009095A (ko) | 합성 항원, 이의 제조방법 및 용도 | |
ES2063965T3 (es) | Vacunas para haemophilus influenzae no tipificable. | |
Muttilainen et al. | TheNeisseria meningitidisouter membrane protein P1 produced inBacillus subtilisand reconstituted into phospholipid vesicles elicits antibodies to native P1 epitopes | |
WO1996021734A3 (en) | P15 and tyrosinase melanoma antigens and their use in diagnostic and therapeutic methods | |
DE68915046D1 (de) | Haemophilus influenzae Typ B Polysaccharid-Aussermembranprotein-Konjugat als Impfstoff. | |
MX9803841A (es) | Compuestos y metodos para la deteccion y prevencion de infeccion por t. cruzi. | |
CA2007248A1 (en) | Meningococcal class 1 outer-membrane protein vaccine | |
BR9905780A (pt) | Antìgenos vacinais de leptospira para prevenção da laptospirose | |
NZ227943A (en) | An antigen derived from the neck region of the rhoptries of merozoites and vaccine against plasmodium falciparum | |
NO912823L (no) | Fremgangsmaate for fremstilling av klasse ii-proteinet av neisseria meningitidis samt vaksiner som inneholder dette. | |
Van Welzijn | Jay R. Luly; Megumi Kawai; Or Yat Sun; Paul Wiedeman; Rolf Wagner Abbott Laboratories, Libertyville, IL, United States | |
Gorlina et al. | Immunochemical properties of a protective cross-reacting antigen of meningococci | |
AU7614798A (en) | High level expression, purification and refolding of the Neisseria meningitidis outer membrane group B porin proteins |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |