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NO922642D0 - Oktadecyl-(2-(n-metylpiperidino)-etyl)-fosfat og fremgangsmaate til dets fremstilling - Google Patents

Oktadecyl-(2-(n-metylpiperidino)-etyl)-fosfat og fremgangsmaate til dets fremstilling

Info

Publication number
NO922642D0
NO922642D0 NO922642A NO922642A NO922642D0 NO 922642 D0 NO922642 D0 NO 922642D0 NO 922642 A NO922642 A NO 922642A NO 922642 A NO922642 A NO 922642A NO 922642 D0 NO922642 D0 NO 922642D0
Authority
NO
Norway
Prior art keywords
methylpiperidino
octadecyl
preparation
phosphate
ethyl
Prior art date
Application number
NO922642A
Other languages
English (en)
Other versions
NO303939B1 (no
NO922642L (no
Inventor
Wolfgang Schumacher
Juergen Engel
Gerhard Noessner
Bernhard Kutscher
Jurij Stekar
Peter Hilgard
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of NO922642D0 publication Critical patent/NO922642D0/no
Publication of NO922642L publication Critical patent/NO922642L/no
Publication of NO303939B1 publication Critical patent/NO303939B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
NO922642A 1991-07-04 1992-07-03 Oktadecyl-£2-(N-metylpiperidiono)-etyl|-fosfat og fremstilling derav, legemiddel omfattende forbindelsen og rensemetode for denne NO303939B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4122140 1991-07-04
DE4129364 1991-09-04

Publications (3)

Publication Number Publication Date
NO922642D0 true NO922642D0 (no) 1992-07-03
NO922642L NO922642L (no) 1993-01-05
NO303939B1 NO303939B1 (no) 1998-09-28

Family

ID=25905206

Family Applications (1)

Application Number Title Priority Date Filing Date
NO922642A NO303939B1 (no) 1991-07-04 1992-07-03 Oktadecyl-£2-(N-metylpiperidiono)-etyl|-fosfat og fremstilling derav, legemiddel omfattende forbindelsen og rensemetode for denne

Country Status (19)

Country Link
US (1) US5219866A (no)
EP (1) EP0521353B1 (no)
JP (1) JP3176720B2 (no)
KR (1) KR100255436B1 (no)
CN (1) CN1030658C (no)
AT (1) ATE136783T1 (no)
AU (1) AU651224B2 (no)
CA (1) CA2073146C (no)
DE (2) DE4219972A1 (no)
DK (1) DK0521353T3 (no)
EG (1) EG20082A (no)
ES (1) ES2086026T3 (no)
FI (1) FI108035B (no)
GR (1) GR3019776T3 (no)
HU (2) HUT61561A (no)
IE (1) IE73200B1 (no)
IL (1) IL102380A (no)
NO (1) NO303939B1 (no)
PL (3) PL173905B1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ538428A (en) * 2002-07-30 2006-09-29 Zentaris Gmbh Use of alkylphosphocholines in combination with antitumor medicaments
US8383605B2 (en) * 2002-07-30 2013-02-26 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
AU2006328479B2 (en) * 2005-12-19 2012-03-08 Aeterna Zentaris Gmbh Alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof
CN101340918B (zh) * 2005-12-19 2012-10-03 阿特纳赞塔里斯有限公司 具有降低细胞毒性的新烷基磷脂衍生物及其用途
JP5068630B2 (ja) * 2007-11-15 2012-11-07 オルガノ株式会社 アルコール含有溶液中のアルデヒド化合物の除去方法及び該方法により精製された醸造酒
CA2794513A1 (en) 2010-03-31 2011-10-06 Aeterna Zentaris Gmbh Perifosine and capecitabine as a combined treatment for cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU301951A1 (ru) * 1970-06-01 1973-04-05 В. А. Чернов, Т. С. Сафонова, Н. В. Сазонов, А. А. Кропачева, Лекарственное средство
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
EP0521297B1 (de) * 1991-07-04 1997-09-17 ASTA Medica Aktiengesellschaft Verfahren zur Herstellung von Alkylphosphocholinen und Reinherstellung derselben

Also Published As

Publication number Publication date
ATE136783T1 (de) 1996-05-15
FI923088A0 (fi) 1992-07-03
IL102380A (en) 1996-10-16
AU651224B2 (en) 1994-07-14
CN1068119A (zh) 1993-01-20
FI923088L (fi) 1993-01-05
PL173869B1 (pl) 1998-05-29
HUT61561A (en) 1993-01-28
DK0521353T3 (da) 1996-05-13
PL173794B1 (pl) 1998-05-29
NO303939B1 (no) 1998-09-28
PL173905B1 (pl) 1998-05-29
JP3176720B2 (ja) 2001-06-18
CN1030658C (zh) 1996-01-10
EG20082A (en) 1997-05-31
EP0521353A1 (de) 1993-01-07
ES2086026T3 (es) 1996-06-16
IE73200B1 (en) 1997-05-07
AU1943592A (en) 1993-03-11
KR930001909A (ko) 1993-02-22
DE59205998D1 (de) 1996-05-23
EP0521353B1 (de) 1996-04-17
IL102380A0 (en) 1993-01-14
GR3019776T3 (en) 1996-07-31
NO922642L (no) 1993-01-05
DE4219972A1 (de) 1993-01-07
JPH05213980A (ja) 1993-08-24
HU211483A9 (en) 1995-11-28
CA2073146A1 (en) 1993-01-05
IE922183A1 (en) 1993-01-13
CA2073146C (en) 2002-05-28
HU9202232D0 (en) 1992-10-28
US5219866A (en) 1993-06-15
KR100255436B1 (ko) 2000-05-01
PL295128A1 (en) 1993-08-23
FI108035B (fi) 2001-11-15

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