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NO920616D0 - Nye inhibitorer for thrombin - Google Patents

Nye inhibitorer for thrombin

Info

Publication number
NO920616D0
NO920616D0 NO920616A NO920616A NO920616D0 NO 920616 D0 NO920616 D0 NO 920616D0 NO 920616 A NO920616 A NO 920616A NO 920616 A NO920616 A NO 920616A NO 920616 D0 NO920616 D0 NO 920616D0
Authority
NO
Norway
Prior art keywords
thrombin
molecules
relates
new inhibitors
moiety
Prior art date
Application number
NO920616A
Other languages
English (en)
Other versions
NO310294B1 (no
NO920616L (no
Inventor
John M Maraganore
Ii John W Fenton
Toni Kline
Original Assignee
Biogen Inc
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27015128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO920616(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Inc, Health Research Inc filed Critical Biogen Inc
Publication of NO920616D0 publication Critical patent/NO920616D0/no
Publication of NO920616L publication Critical patent/NO920616L/no
Publication of NO310294B1 publication Critical patent/NO310294B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19920616A 1989-08-18 1992-02-17 Nye inhibitorer for trombin NO310294B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39548289A 1989-08-18 1989-08-18
US07549388 US5196404B1 (en) 1989-08-18 1990-07-06 Inhibitors of thrombin
PCT/US1990/004642 WO1991002750A1 (en) 1989-08-18 1990-08-17 Novel inhibitors of thrombin

Publications (3)

Publication Number Publication Date
NO920616D0 true NO920616D0 (no) 1992-02-17
NO920616L NO920616L (no) 1992-04-13
NO310294B1 NO310294B1 (no) 2001-06-18

Family

ID=27015128

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19920616A NO310294B1 (no) 1989-08-18 1992-02-17 Nye inhibitorer for trombin
NO2004008C NO2004008I2 (no) 1989-08-18 2004-11-29 Bivalirudin

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2004008C NO2004008I2 (no) 1989-08-18 2004-11-29 Bivalirudin

Country Status (18)

Country Link
US (3) US5196404B1 (no)
EP (1) EP0489070B1 (no)
JP (1) JPH0768141B2 (no)
KR (1) KR100199534B1 (no)
AT (1) ATE137246T1 (no)
AU (1) AU652125B2 (no)
CA (1) CA2065150C (no)
DE (2) DE69026715T2 (no)
DK (1) DK0489070T3 (no)
ES (1) ES2086411T3 (no)
FI (1) FI102183B (no)
HK (1) HK1001562A1 (no)
HU (2) HUT60285A (no)
LU (1) LU91119I2 (no)
NL (1) NL300162I1 (no)
NO (2) NO310294B1 (no)
SG (1) SG79180A1 (no)
WO (1) WO1991002750A1 (no)

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US6291662B1 (en) 1984-12-05 2001-09-18 Amgen Inc. Recombinant methods for production of serine protease inhibitors and DNA sequences
US6132990A (en) * 1984-12-06 2000-10-17 Amgen Boulder Inc. Recombinant methods for production of serine protease inhibitors and DNA sequences useful for same
US5900400A (en) * 1984-12-06 1999-05-04 Amgen Inc. Serine protease inhibitor analogs
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
DE4005591A1 (de) * 1990-02-22 1991-09-05 Behringwerke Ag Die blutgerinnung inhibierende peptide, verfahren zu ihrer herstellung und ihre verwendung
US6060451A (en) * 1990-06-15 2000-05-09 The National Research Council Of Canada Thrombin inhibitors based on the amino acid sequence of hirudin
HUT63440A (en) 1990-06-15 1993-08-30 Ca Nat Research Council Proccess for producing thrombin inhibitors based on amino acid sequence of hirudine and pharmaceutical compositions comprising same
US5242810A (en) * 1990-12-07 1993-09-07 Biogen, Inc. Bifunctional inhibitors of thrombin and platelet activation
US5736122A (en) * 1991-02-08 1998-04-07 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
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US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
CA2136330C (en) * 1992-05-21 2002-03-19 Richard T. Dean Technetium-99m labeled peptides for thrombus imaging
WO1993025220A1 (en) * 1992-06-05 1993-12-23 Reid Thomas J Iii Test for quantitative thrombin time
US5476771A (en) * 1993-02-22 1995-12-19 The United States Of America As Represented By The Secretary Of The Army Test for quantitative thrombin time
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US6869925B1 (en) * 1992-09-09 2005-03-22 Amgen Inc. Inhibition of retrovirus infection
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Also Published As

Publication number Publication date
DE69026715D1 (en) 1996-05-30
FI102183B1 (fi) 1998-10-30
US5433940A (en) 1995-07-18
ES2086411T3 (es) 1996-07-01
DE122004000042I1 (de) 2005-02-24
EP0489070A1 (en) 1992-06-10
US5196404A (en) 1993-03-23
AU652125B2 (en) 1994-08-18
HU9200473D0 (en) 1992-05-28
NL300162I2 (nl) 2005-01-03
LU91119I2 (fr) 2004-12-29
NL300162I1 (nl) 2005-01-03
HK1001562A1 (en) 1998-06-26
KR100199534B1 (en) 1999-06-15
DE122004000042I2 (de) 2008-01-24
CA2065150C (en) 1999-12-14
SG79180A1 (en) 2001-03-20
ATE137246T1 (de) 1996-05-15
AU6284190A (en) 1991-04-03
CA2065150A1 (en) 1991-02-19
US5691311A (en) 1997-11-25
JPH04507253A (ja) 1992-12-17
EP0489070B1 (en) 1996-04-24
US5196404B1 (en) 1996-09-10
NO2004008I1 (no) 2004-12-27
FI102183B (fi) 1998-10-30
WO1991002750A1 (en) 1991-03-07
NO2004008I2 (no) 2008-01-28
JPH0768141B2 (ja) 1995-07-26
DE69026715T2 (de) 1996-10-17
HU211158A9 (en) 1995-10-30
HUT60285A (en) 1992-08-28
DK0489070T3 (da) 1996-07-15
NO310294B1 (no) 2001-06-18
FI920672A0 (fi) 1992-02-17
NO920616L (no) 1992-04-13
KR920702372A (ko) 1992-09-03

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