NO882341L - Ekspresjon av humant proapolipoprotein a-i. - Google Patents
Ekspresjon av humant proapolipoprotein a-i.Info
- Publication number
- NO882341L NO882341L NO88882341A NO882341A NO882341L NO 882341 L NO882341 L NO 882341L NO 88882341 A NO88882341 A NO 88882341A NO 882341 A NO882341 A NO 882341A NO 882341 L NO882341 L NO 882341L
- Authority
- NO
- Norway
- Prior art keywords
- proapolipoprotein
- sequence
- expression
- expression vectors
- humant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878712540A GB8712540D0 (en) | 1987-05-28 | 1987-05-28 | Expression of human proapolipoprotein a-i |
Publications (4)
Publication Number | Publication Date |
---|---|
NO882341D0 NO882341D0 (no) | 1988-05-27 |
NO882341L true NO882341L (no) | 1988-11-29 |
NO179253B NO179253B (no) | 1996-05-28 |
NO179253C NO179253C (no) | 1996-09-04 |
Family
ID=10618034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO882341A NO179253C (no) | 1987-05-28 | 1988-05-27 | Rekombinant DNA-sekvens som koder for humant proapolipoprotein A-I, ekspresjonsvektorer, cellekulturer samt fremgangsmåte for fremstilling av proteinet |
Country Status (33)
Country | Link |
---|---|
US (1) | US5059528A (no) |
EP (1) | EP0293357B1 (no) |
JP (1) | JP2634193B2 (no) |
KR (1) | KR970000808B1 (no) |
CN (1) | CN1031892C (no) |
AT (1) | ATE89006T1 (no) |
AU (1) | AU615654B2 (no) |
CA (1) | CA1323851C (no) |
CY (1) | CY1809A (no) |
CZ (1) | CZ283648B6 (no) |
DD (1) | DD291093A5 (no) |
DE (1) | DE3880739T2 (no) |
DK (1) | DK175686B1 (no) |
EG (1) | EG19101A (no) |
ES (1) | ES2054878T3 (no) |
FI (1) | FI100056B (no) |
GB (1) | GB8712540D0 (no) |
HK (1) | HK137794A (no) |
HU (1) | HU204562B (no) |
IE (1) | IE62422B1 (no) |
IL (1) | IL86480A (no) |
LT (1) | LT3600B (no) |
LV (1) | LV5288A3 (no) |
NO (1) | NO179253C (no) |
NZ (1) | NZ224808A (no) |
PL (1) | PL158064B1 (no) |
PT (1) | PT87562B (no) |
RU (1) | RU2009198C1 (no) |
SG (1) | SG131594G (no) |
SK (1) | SK279166B6 (no) |
SU (1) | SU1834904A3 (no) |
UA (1) | UA19765A (no) |
ZA (1) | ZA883824B (no) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU587989B2 (en) * | 1984-10-16 | 1989-09-07 | Mitsubishi Chemical Corporation | DMA fragments, expression vectors, proteins, hosts, and process for production of the proteins |
JP2606228B2 (ja) * | 1987-09-18 | 1997-04-30 | 三菱化学株式会社 | ヒトプロアポリポプロテインa−i様蛋白の産生法 |
DE68917379T2 (de) * | 1988-05-31 | 1994-12-01 | Mitsubishi Chem Ind | Verfahren zur Herstellung von Proteinen, die ähnlich dem natürlich-menschlichen Apolipoprotein-E sind. |
US5846799A (en) * | 1988-06-14 | 1998-12-08 | La Region Wallone | Human myeloperoxidase and its therapeutic application |
US5460961A (en) * | 1988-06-14 | 1995-10-24 | La Region Wallonne | Human myeloperoxidase and its therapeutic application |
IT1229996B (it) * | 1989-04-20 | 1991-09-20 | Cesare Sirtori | Espressione di apolipoproteina ai e apolipoproteina ai-milano in lievito e composizioni farmaceutiche che contengono dette apolipoproteine. |
ATE158816T1 (de) * | 1990-11-26 | 1997-10-15 | Genetics Inst | Expression von pace in wirtszellen und verfahren zu dessen verwendung |
WO1992010760A1 (en) * | 1990-11-30 | 1992-06-25 | Monoclonetics International, Incorporated | Methods for the diagnosis of chronic lower back and cervical pain |
US5844097A (en) * | 1990-11-30 | 1998-12-01 | Monoclonetics International, Inc. | Methods for the diagnosis of peripheral nerve damage |
SE9500778D0 (sv) * | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
US5994061A (en) * | 1995-09-29 | 1999-11-30 | Queen's University At Kingston | DNA constructs and methods for screening for increased expression of human apo AI gene |
SE9603068D0 (sv) | 1996-08-23 | 1996-08-23 | Pharmacia & Upjohn Ab | Process for purifying a protein |
SE9603304D0 (sv) * | 1996-09-11 | 1996-09-11 | Pharmacia & Upjohn Ab | Process for purifying a compound |
SE9603303D0 (sv) | 1996-09-11 | 1996-09-11 | Pharmacia & Upjohn Ab | Process for purifying a protein |
KR100330355B1 (ko) * | 1999-06-04 | 2002-04-01 | 장인순 | 회전유동발생 날개를 가진 덕트형 핵연료 집합체 지지격자 |
US20040047853A1 (en) * | 2000-06-09 | 2004-03-11 | Dahl Soren W | Purified proenzyme of dipeptidyl peptidase i (pro-dppi) |
AU2002232642B2 (en) * | 2000-12-12 | 2007-02-01 | Lexicon Pharmaceuticals, Inc. | Novel human kinases and uses thereof |
KR100560102B1 (ko) * | 2004-06-25 | 2006-03-13 | 한국생명공학연구원 | 프로아포리포단백질 a-ⅰ 변이체와, 이를 포함하는고지혈증 또는 동맥경화증 예방 및 치료제 |
US7427662B2 (en) * | 2005-02-01 | 2008-09-23 | Baord Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Inhibition of angiogenesis and destruction of angiogenic vessels by apolipoprotein A-I and high density lipoprotein |
US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
WO2007023476A2 (en) * | 2005-08-26 | 2007-03-01 | Cerenis Therapeutics Holding Sa | Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria |
US20080293102A1 (en) * | 2007-02-28 | 2008-11-27 | Cerenis Therapeutics Holding, S.A. | Compositions and methods for producing apolipoprotein |
MX339820B (es) * | 2008-10-03 | 2016-06-13 | Curna Inc | Compuestos oligonucleottidos designados para inhibir el transcrito antisentido natrual apra apolipoproteina-a1. |
SG10201901089TA (en) | 2008-11-10 | 2019-03-28 | Arbutus Biopharma Corp | Novel lipids and compositions for the delivery of therapeutics |
CA2751342C (en) | 2009-01-29 | 2019-05-07 | Alnylam Pharmaceuticals, Inc. | Lipid formulations comprising cationic lipid and a targeting lipid comprising n-acetyl galactosamine for delivery of nucleic acid |
NZ594995A (en) | 2009-03-12 | 2013-06-28 | Alnylam Pharmaceuticals Inc | LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF HUMAN KINESIN FAMILY MEMBER 11 (Eg5) AND VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) GENES |
NZ711583A (en) | 2009-05-05 | 2017-03-31 | Arbutus Biopharma Corp | Lipid compositions |
CN102459596B (zh) | 2009-05-06 | 2016-09-07 | 库尔纳公司 | 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病 |
SMT202100696T1 (it) | 2009-06-10 | 2022-01-10 | Arbutus Biopharma Corp | Formulazione lipidica migliorata |
EP2464336A4 (en) | 2009-08-14 | 2013-11-20 | Alnylam Pharmaceuticals Inc | COMPOSITIONS FORMULATED IN LIPIDS AND METHODS OF INHIBITING THE EXPRESSION OF EBOLA VIRUS GENE |
US10894098B2 (en) | 2012-04-09 | 2021-01-19 | Signablok, Inc. | Methods and compositions for targeted imaging |
US10525152B2 (en) | 2009-10-09 | 2020-01-07 | Signablok, Inc. | Methods and compositions for targeted imaging |
US9687550B2 (en) | 2009-12-07 | 2017-06-27 | Arbutus Biopharma Corporation | Compositions for nucleic acid delivery |
NZ600725A (en) | 2009-12-18 | 2015-08-28 | Univ British Colombia | Methods and compositions for delivery of nucleic acids |
US20130156845A1 (en) | 2010-04-29 | 2013-06-20 | Alnylam Pharmaceuticals, Inc. | Lipid formulated single stranded rna |
US20130137628A1 (en) | 2010-05-11 | 2013-05-30 | Esperion Therapeutics, Inc. | Dimeric Oxidation-Resistant Apolipoprotein A1 Variants |
KR20190039347A (ko) | 2010-06-03 | 2019-04-10 | 알닐람 파마슈티칼스 인코포레이티드 | 활성제의 전달을 위한 생분해성 지질 |
WO2012016184A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
WO2012016188A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
CN103370054A (zh) | 2010-11-09 | 2013-10-23 | 阿尔尼拉姆医药品有限公司 | 用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法 |
DK3202760T3 (da) | 2011-01-11 | 2019-11-25 | Alnylam Pharmaceuticals Inc | Pegylerede lipider og deres anvendelse til lægemiddelfremføring |
JP6219170B2 (ja) | 2011-02-07 | 2017-10-25 | セレニス セラピューティクス ホールディング エスアー | リポタンパク質複合体ならびにその製造および使用 |
AU2012315965A1 (en) | 2011-09-27 | 2014-04-03 | Alnylam Pharmaceuticals, Inc. | Di-aliphatic substituted PEGylated lipids |
WO2014011908A1 (en) | 2012-07-11 | 2014-01-16 | Esperion Therapeutics, Inc. | Apolipoprotein mixtures |
JP6387084B2 (ja) * | 2013-05-01 | 2018-09-05 | アイオーニス ファーマシューティカルズ, インコーポレーテッドIonis Pharmaceuticals,Inc. | アポリポタンパク質c−iiiの発現を調節するための組成物および方法 |
EP2853259A1 (en) | 2013-09-30 | 2015-04-01 | Université Pierre et Marie Curie (Paris 6) | Reconstituted high density lipoproteins composition and uses thereof |
MX2016014306A (es) | 2014-05-02 | 2017-06-12 | Cerenis Therapeutics Holding Sa | Marcadores para terapia con lipoproteinas de alta densidad (hdl). |
CN108473990A (zh) * | 2016-10-27 | 2018-08-31 | 中国科学院微生物研究所 | 氨基酸衰减子的改造方法及其在生产中的应用 |
EP3668549B1 (en) | 2017-08-10 | 2024-05-15 | Abionyx Pharma SA | Apomers |
WO2019030574A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | CARGOMÈRES |
US11461863B2 (en) | 2018-08-24 | 2022-10-04 | Bright Marbles, Inc. | Idea assessment and landscape mapping |
US11081113B2 (en) | 2018-08-24 | 2021-08-03 | Bright Marbles, Inc. | Idea scoring for creativity tool selection |
US11189267B2 (en) | 2018-08-24 | 2021-11-30 | Bright Marbles, Inc. | Intelligence-driven virtual assistant for automated idea documentation |
US11164065B2 (en) | 2018-08-24 | 2021-11-02 | Bright Marbles, Inc. | Ideation virtual assistant tools |
JP2023522889A (ja) | 2020-04-16 | 2023-06-01 | アビオニクス ファーマ エスエー | 脂質結合タンパク質ベースの複合体を使用した、急性病態を治療するための方法 |
EP4221686A2 (en) | 2020-10-01 | 2023-08-09 | Abionyx Pharma SA | Compositions comprising lipid binding protein-based complexes for use for treating eye diseases |
MX2023012223A (es) | 2021-04-15 | 2023-10-26 | Abionyx Pharma Sa | Uso de complejos a base de proteinas de union a lipidos en soluciones de conservacion de organos. |
WO2023194797A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
CN119317440A (zh) | 2022-04-06 | 2025-01-14 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗白细胞增多、内皮功能障碍和心脏炎的方法 |
AU2023284357A1 (en) | 2022-06-10 | 2025-01-23 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
IL317448A (en) | 2022-06-10 | 2025-02-01 | Abionyx Pharma Sa | Methods for treating hyperinflammatory conditions using complexes based on lipid-binding proteins |
WO2024150064A1 (en) | 2023-01-13 | 2024-07-18 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU587989B2 (en) * | 1984-10-16 | 1989-09-07 | Mitsubishi Chemical Corporation | DMA fragments, expression vectors, proteins, hosts, and process for production of the proteins |
JPS6198998A (ja) | 1984-10-18 | 1986-05-17 | Matsushita Electric Ind Co Ltd | 電動送風機 |
BE901119A (fr) | 1984-11-23 | 1985-03-15 | Wallone Region | Procede de preparation de plasmides vecteurs capables de transformer un hote bacterien escherichia coli et d'y promouvoir et controler l'expression d'un adn heterologue. |
AU580145B2 (en) | 1985-02-13 | 1989-01-05 | Scios Nova Inc. | Human metallothionein-ii promoter in mammalian expression system |
GB8507833D0 (en) * | 1985-03-26 | 1985-05-01 | Biogen Nv | Production of human somatomedin c |
EP0239631A4 (en) | 1985-10-04 | 1989-01-12 | Biotech Res Partners Ltd | RECOMBINANT APOLIPOPROTEINS AND METHODS. |
GB8625435D0 (en) * | 1986-10-23 | 1986-11-26 | Erba Farmitalia | Human apolipoprotein ai |
AU8273987A (en) * | 1986-10-29 | 1988-05-25 | Biotechnology Research Partners Limited | Apoai-ciii-aiv, apoaii apob , apoci, and ldl receptor polymorphisms for genetic fingerprinting and predictive of atherosclerosis |
-
1987
- 1987-05-28 GB GB878712540A patent/GB8712540D0/en active Pending
-
1988
- 1988-05-16 CA CA000566894A patent/CA1323851C/en not_active Expired - Fee Related
- 1988-05-24 DE DE8888870095T patent/DE3880739T2/de not_active Expired - Lifetime
- 1988-05-24 ES ES88870095T patent/ES2054878T3/es not_active Expired - Lifetime
- 1988-05-24 PT PT87562A patent/PT87562B/pt not_active IP Right Cessation
- 1988-05-24 IL IL86480A patent/IL86480A/xx not_active IP Right Cessation
- 1988-05-24 AT AT88870095T patent/ATE89006T1/de not_active IP Right Cessation
- 1988-05-24 EP EP88870095A patent/EP0293357B1/fr not_active Expired - Lifetime
- 1988-05-25 FI FI882456A patent/FI100056B/fi not_active IP Right Cessation
- 1988-05-26 SU SU884356123A patent/SU1834904A3/ru active
- 1988-05-26 NZ NZ224808A patent/NZ224808A/en unknown
- 1988-05-26 PL PL1988272698A patent/PL158064B1/pl unknown
- 1988-05-26 DD DD88316110A patent/DD291093A5/de not_active IP Right Cessation
- 1988-05-26 US US07/198,830 patent/US5059528A/en not_active Expired - Lifetime
- 1988-05-26 EG EG28288A patent/EG19101A/xx active
- 1988-05-26 UA UA4613079A patent/UA19765A/uk unknown
- 1988-05-27 CN CN88103118A patent/CN1031892C/zh not_active Expired - Fee Related
- 1988-05-27 CZ CS883638A patent/CZ283648B6/cs not_active IP Right Cessation
- 1988-05-27 HU HU882707A patent/HU204562B/hu not_active IP Right Cessation
- 1988-05-27 DK DK198802896A patent/DK175686B1/da not_active IP Right Cessation
- 1988-05-27 SK SK3638-88A patent/SK279166B6/sk unknown
- 1988-05-27 IE IE159788A patent/IE62422B1/en not_active IP Right Cessation
- 1988-05-27 AU AU16723/88A patent/AU615654B2/en not_active Ceased
- 1988-05-27 JP JP63130033A patent/JP2634193B2/ja not_active Expired - Fee Related
- 1988-05-27 ZA ZA883824A patent/ZA883824B/xx unknown
- 1988-05-27 NO NO882341A patent/NO179253C/no not_active IP Right Cessation
- 1988-05-28 KR KR88006286A patent/KR970000808B1/ko not_active IP Right Cessation
- 1988-12-20 RU SU884613079A patent/RU2009198C1/ru active
-
1993
- 1993-06-01 LV LV930445A patent/LV5288A3/xx unknown
- 1993-08-03 LT LTIP828A patent/LT3600B/lt not_active IP Right Cessation
-
1994
- 1994-09-12 SG SG131594A patent/SG131594G/en unknown
- 1994-12-08 HK HK137794A patent/HK137794A/xx not_active IP Right Cessation
-
1995
- 1995-10-20 CY CY180995A patent/CY1809A/xx unknown
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |