NO327453B1 - Anvendelse av et alfa-amionoamid for fremstilling av et medikament for bruk som et smertestillende middel - Google Patents

Anvendelse av et alfa-amionoamid for fremstilling av et medikament for bruk som et smertestillende middel Download PDF

Info

Publication number: NO327453B1
Authority: NO; Norway
Prior art keywords: sub; propanamide; hydrogen; alkyl; benzylamino
Prior art date: 1997-12-31

Application number

NO20003399A

Other languages

English (en)

Norwegian (no)

Other versions

NO20003399D0 (no

NO20003399L (no

Inventor

Mario Varasi

Paolo Pevarello

Patricia Salvati

Claes Post

Original Assignee

Newron Pharm Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-31

Filing date

2000-06-29

Publication date

2009-07-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10824342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO327453(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-06-29 Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa

2000-06-29 Publication of NO20003399D0 publication Critical patent/NO20003399D0/no

2000-08-02 Publication of NO20003399L publication Critical patent/NO20003399L/no

2009-07-06 Publication of NO327453B1 publication Critical patent/NO327453B1/no

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

NO20003399A 1997-12-31 2000-06-29 Anvendelse av et alfa-amionoamid for fremstilling av et medikament for bruk som et smertestillende middel NO327453B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9727523.4A GB9727523D0 (en)	1997-12-31	1997-12-31	Alpha-aminoamide derivatives useful as analgesic agents
PCT/EP1998/008157 WO1999035125A1 (en)	1997-12-31	1998-12-12	Alpha-aminoamide derivatives useful as analgesic agents

Publications (3)

Publication Number	Publication Date
NO20003399D0 NO20003399D0 (no)	2000-06-29
NO20003399L NO20003399L (no)	2000-08-02
NO327453B1 true NO327453B1 (no)	2009-07-06

Family

ID=10824342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20003399A NO327453B1 (no)	1997-12-31	2000-06-29	Anvendelse av et alfa-amionoamid for fremstilling av et medikament for bruk som et smertestillende middel

Country Status (19)

Country	Link
US (2)	USRE40259E1 (hu)
EP (1)	EP1045830B1 (hu)
JP (1)	JP4410930B2 (hu)
KR (1)	KR100525587B1 (hu)
AT (1)	ATE238273T1 (hu)
BR (1)	BR9814548A (hu)
CA (1)	CA2316902C (hu)
DE (1)	DE69813896T2 (hu)
DK (1)	DK1045830T3 (hu)
EA (1)	EA002763B1 (hu)
ES (1)	ES2194392T3 (hu)
GB (1)	GB9727523D0 (hu)
HK (1)	HK1028020A1 (hu)
HU (1)	HU228995B1 (hu)
IL (2)	IL136734A0 (hu)
NO (1)	NO327453B1 (hu)
NZ (1)	NZ505440A (hu)
PT (1)	PT1045830E (hu)
WO (1)	WO1999035125A1 (hu)

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EP1438956A1 (en) *	2003-01-16	2004-07-21	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful as antimigraine agents
WO2004087125A1 (en) *	2003-04-02	2004-10-14	Ionix Pharmaceuticals Limited	Amino acid derivatives as inhibitors of mammalian sodium channels
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US20070276046A1 (en) *	2003-08-25	2007-11-29	Patricia Salvati	Alpha-Aminoamide Derivatives Useful as Anti-Inflammatory Agents
EP1524267A1 (en) *	2003-10-15	2005-04-20	Newron Pharmaceuticals S.p.A.	Substituted benzylaminoalkylene heterocycles
EP1533298A1 (en) *	2003-11-21	2005-05-25	Newron Pharmaceuticals S.p.A.	3-aminopyrrolidone derivatives
EP1533302A1 (en) *	2003-11-21	2005-05-25	Newron Pharmaceuticals S.p.A.	Histidine derivatives
EP1533295A1 (en) *	2003-11-24	2005-05-25	Newron Pharmaceuticals S.p.A.	Cyclopentyl Derivatives
EP1535908A1 (en)	2003-11-24	2005-06-01	Newron Pharmaceuticals S.p.A.	N-acyl-N'-benzyl-alkylendiamino drivatives
EP1557166A1 (en) *	2004-01-21	2005-07-27	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
EP1588704A1 (en)	2004-04-22	2005-10-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
ME01801B (me) *	2004-09-10	2011-02-28	Newron Pharm Spa	UPOTREBA (R)-(HALOBENZILOKSI) BENZILAMINO-PROPANAMIDA KAO SELEKTIVNIH MODULATORA NATRIJUMOVIH l/ILI KALCIJUMOVIH KANALA
ATE472529T1 (de) *	2005-10-10	2010-07-15	Glaxo Group Ltd	Prolinamidderivate als natriumkanalmodulatoren
TW200730494A (en)	2005-10-10	2007-08-16	Glaxo Group Ltd	Novel compounds
TW200728258A (en)	2005-10-10	2007-08-01	Glaxo Group Ltd	Novel compounds
DK1963280T3 (en) *	2005-12-22	2015-12-14	Newron Pharm Spa	2-phenylethylamine derivatives by calcium and / or sodium channel
EP1870097A1 (en) *	2006-06-15	2007-12-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
JP5240476B2 (ja)	2006-06-19	2013-07-17	ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー	２−［４−（３−及び２−フルオロベンジルオキシ）ベンジルアミノ］プロパンアミドの製造方法
AU2008261325B2 (en)	2007-06-15	2012-12-06	Newron Pharmaceuticals S.P.A.	Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
HUE036232T2 (hu)	2007-12-11	2018-06-28	Newron Pharm Spa	Eljárás nagy tisztasági fokú 2-[4-(3- vagy 2-fluorbenziloxi)-benzilamino]- propánamidok elõállítására
EP2314569A1 (en)	2009-10-22	2011-04-27	Merck Patent GmbH	Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
CN102858330B (zh)	2010-04-27	2015-07-22	纽朗制药有限公司	用于制备拉非酰胺甲磺酸盐或其r-对映异构体的方法
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1997
- 1997-12-31 GB GBGB9727523.4A patent/GB9727523D0/en not_active Ceased
1998
- 1998-12-12 BR BR9814548-7A patent/BR9814548A/pt not_active Application Discontinuation
- 1998-12-12 ES ES98966617T patent/ES2194392T3/es not_active Expired - Lifetime
- 1998-12-12 PT PT98966617T patent/PT1045830E/pt unknown
- 1998-12-12 CA CA002316902A patent/CA2316902C/en not_active Expired - Lifetime
- 1998-12-12 KR KR10-2000-7007229A patent/KR100525587B1/ko not_active IP Right Cessation
- 1998-12-12 HU HU0100870A patent/HU228995B1/hu unknown
- 1998-12-12 WO PCT/EP1998/008157 patent/WO1999035125A1/en active IP Right Grant
- 1998-12-12 DK DK98966617T patent/DK1045830T3/da active
- 1998-12-12 AT AT98966617T patent/ATE238273T1/de active
- 1998-12-12 JP JP2000527527A patent/JP4410930B2/ja not_active Expired - Lifetime
- 1998-12-12 EP EP98966617A patent/EP1045830B1/en not_active Expired - Lifetime
- 1998-12-12 DE DE69813896T patent/DE69813896T2/de not_active Expired - Lifetime
- 1998-12-12 EA EA200000731A patent/EA002763B1/ru not_active IP Right Cessation
- 1998-12-12 US US11/359,982 patent/USRE40259E1/en not_active Expired - Lifetime
- 1998-12-12 NZ NZ505440A patent/NZ505440A/en not_active IP Right Cessation
- 1998-12-12 US US09/582,198 patent/US6306903B1/en not_active Ceased
- 1998-12-12 IL IL13673498A patent/IL136734A0/xx active IP Right Grant
2000
- 2000-06-13 IL IL136734A patent/IL136734A/en not_active IP Right Cessation
- 2000-06-29 NO NO20003399A patent/NO327453B1/no not_active IP Right Cessation
- 2000-11-20 HK HK00107398A patent/HK1028020A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB9727523D0 (en)	1998-02-25
CA2316902C (en)	2006-06-06
WO1999035125A1 (en)	1999-07-15
HK1028020A1 (en)	2001-02-02
HU228995B1 (en)	2013-07-29
USRE40259E1 (en)	2008-04-22
EP1045830A1 (en)	2000-10-25
DE69813896D1 (de)	2003-05-28
BR9814548A (pt)	2000-10-10
EA002763B1 (ru)	2002-08-29
EP1045830B1 (en)	2003-04-23
NO20003399D0 (no)	2000-06-29
IL136734A0 (en)	2001-06-14
IL136734A (en)	2007-03-08
KR100525587B1 (ko)	2005-11-03
HUP0100870A2 (hu)	2001-07-30
HUP0100870A3 (en)	2002-11-28
DE69813896T2 (de)	2003-11-06
NZ505440A (en)	2002-02-01
ATE238273T1 (de)	2003-05-15
NO20003399L (no)	2000-08-02
DK1045830T3 (da)	2003-08-04
CA2316902A1 (en)	1999-07-15
ES2194392T3 (es)	2003-11-16
JP4410930B2 (ja)	2010-02-10
EA200000731A1 (ru)	2001-02-26
KR20010033706A (ko)	2001-04-25
US6306903B1 (en)	2001-10-23
PT1045830E (pt)	2003-08-29
JP2002508302A (ja)	2002-03-19

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NZ262907A (en)	1996-02-27	Phenylalkyloxybenzylaminoacetamide, derivatives thereof and medicaments
CA2536764A1 (en)	2005-03-03	.alpha.-aminoamide derivatives useful as anti-inflammatory agents
MXPA00006352A (en)	2002-06-05	Alpha-aminoamide derivatives useful as analgesic agents
WO2019099760A1 (en)	2019-05-23	Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures
MXPA00006354A (en)	2002-06-05	Substituted 2-benzylamino-2-phenyl-acetamide compounds

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2019-01-14	MK1K	Patent expired