NO311672B1 - Nye forbindelser, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelser, og fremgangsmåter for deresfremstilling - Google Patents

Nye forbindelser, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelser, og fremgangsmåter for deresfremstilling Download PDF

Info

Publication number: NO311672B1
Authority: NO; Norway
Prior art keywords: compound; formula; compound according; pharmaceutically acceptable; acceptable salt
Prior art date: 1996-06-10

Application number

NO19985764A

Other languages

English (en)

Norwegian (no)

Other versions

NO985764L (no

NO985764D0 (no

Inventor

Kosrat Amin

Mikael Dahlstroem

Peter Nordberg

Ingemar Starke

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-10

Filing date

1998-12-09

Publication date

2002-01-02

1998-12-09 Application filed by Astra Ab filed Critical Astra Ab

1998-12-09 Publication of NO985764L publication Critical patent/NO985764L/no

1998-12-09 Publication of NO985764D0 publication Critical patent/NO985764D0/no

2002-01-02 Publication of NO311672B1 publication Critical patent/NO311672B1/no

Links

150000001875 compounds Chemical class 0.000 title claims description 121
238000002360 preparation method Methods 0.000 title claims description 23
238000000034 method Methods 0.000 title claims description 13
239000000825 pharmaceutical preparation Substances 0.000 title description 4
150000003839 salts Chemical class 0.000 claims description 26
125000000217 alkyl group Chemical group 0.000 claims description 16
125000000623 heterocyclic group Chemical group 0.000 claims description 10
238000004519 manufacturing process Methods 0.000 claims description 10
238000011282 treatment Methods 0.000 claims description 10
239000004480 active ingredient Substances 0.000 claims description 9
BSMKWPQXLZDVIV-UHFFFAOYSA-N n-[(2,6-dimethylphenyl)methyl]-2-methyl-1h-benzimidazol-4-amine Chemical compound C=12NC(C)=NC2=CC=CC=1NCC1=C(C)C=CC=C1C BSMKWPQXLZDVIV-UHFFFAOYSA-N 0.000 claims description 8
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO19985764A 1996-06-10 1998-12-09 Nye forbindelser, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelser, og fremgangsmåter for deresfremstilling NO311672B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9602286A SE9602286D0 (sv)	1996-06-10	1996-06-10	New compounds
PCT/SE1997/000991 WO1997047603A1 (en)	1996-06-10	1997-06-05	New compounds

Publications (3)

Publication Number	Publication Date
NO985764L NO985764L (no)	1998-12-09
NO985764D0 NO985764D0 (no)	1998-12-09
NO311672B1 true NO311672B1 (no)	2002-01-02

Family

ID=20402945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19985764A NO311672B1 (no)	1996-06-10	1998-12-09	Nye forbindelser, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelser, og fremgangsmåter for deresfremstilling

Country Status (33)

Country	Link
US (1)	US6465505B1 (et)
EP (1)	EP0906288B1 (et)
JP (1)	JP2000512291A (et)
CN (1)	CN1101385C (et)
AR (1)	AR007352A1 (et)
AT (1)	ATE227273T1 (et)
AU (1)	AU712173B2 (et)
BR (1)	BR9709666A (et)
CA (1)	CA2256687C (et)
CZ (1)	CZ291469B6 (et)
DE (1)	DE69716904T2 (et)
DK (1)	DK0906288T3 (et)
EE (1)	EE03682B1 (et)
ES (1)	ES2184097T3 (et)
HK (1)	HK1017351A1 (et)
HU (1)	HUP0002952A3 (et)
ID (1)	ID18431A (et)
IL (1)	IL127432A0 (et)
IS (1)	IS1864B (et)
MY (1)	MY119012A (et)
NO (1)	NO311672B1 (et)
NZ (1)	NZ332965A (et)
PL (1)	PL330525A1 (et)
PT (1)	PT906288E (et)
RU (1)	RU2184113C2 (et)
SA (1)	SA97180427B1 (et)
SE (1)	SE9602286D0 (et)
SK (1)	SK282704B6 (et)
TR (1)	TR199802554T2 (et)
TW (1)	TW470742B (et)
UA (1)	UA64714C2 (et)
WO (1)	WO1997047603A1 (et)
ZA (1)	ZA974681B (et)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9704404D0 (sv)	1997-11-28	1997-11-28	Astra Ab	New compounds
AR043063A1 (es) *	2002-12-13	2005-07-13	Altana Pharma Ag	Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
KR20060015483A (ko)	2003-04-04	2006-02-17	알타나 파마 아게	시클릭 벤즈이미다졸
AR046893A1 (es) *	2003-12-16	2005-12-28	Altana Pharma Ag	Bencimidazoles triciclicos
AR048869A1 (es) *	2004-04-26	2006-06-07	Altana Pharma Ag	Bencimidazoles triciclicos
AR049168A1 (es) *	2004-05-18	2006-07-05	Altana Pharma Ag	Derivados de benzimidazol
ATE374774T1 (de) *	2004-06-09	2007-10-15	Nycomed Gmbh	Substituierte tricyclische benzimidazole
CA2582256A1 (en) *	2004-10-01	2006-04-13	Altana Pharma Ag	Substituted tricyclic benzimidazoles
AR051041A1 (es) *	2004-10-04	2006-12-13	Altana Pharma Ag	Bencimidazoles triciclicos condensados
US7718809B2 (en)	2005-06-14	2010-05-18	Raqualia Pharma Inc.	Chromane substituted benzimidazole derivatives as acid pump antagonists
AU2006283876A1 (en) *	2005-08-22	2007-03-01	Nycomed Gmbh	Isotopically substituted benzimidazole derivatives
WO2007072142A2 (en) *	2005-12-19	2007-06-28	Pfizer Japan Inc.	Benzimidazole-5-carboxamide derivatives
KR101088247B1 (ko) *	2005-12-19	2011-11-30	라퀄리아 파마 인코포레이티드	크로메인 치환된 벤즈이미다졸 및 이들의 산 펌프억제제로서의 용도
US20080027044A1 (en) *	2006-06-13	2008-01-31	Kim Lewis	Prodrug antibiotic screens
CA2668925A1 (en) *	2006-11-10	2008-05-22	The Regents Of The University Of California	Atmospheric pressure plasma-induced graft polymerization
US20110046142A1 (en) *	2007-06-13	2011-02-24	Northeastern University	Antibiotic compounds
WO2008151927A2 (en) *	2007-06-15	2008-12-18	Nycomed Gmbh	6-n-substituted benz imidazole derivatives as acid pump antagonists
US8445076B2 (en) *	2008-06-11	2013-05-21	The Regents Of The University Of California	Fouling and scaling resistant nano-structured reverse osmosis membranes
KR101472686B1 (ko)	2013-07-09	2014-12-16	씨제이헬스케어 주식회사	벤즈이미다졸 유도체의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8604566D0 (sv)	1986-10-27	1986-10-27	Haessle Ab	Novel compunds
DE3770117D1 (de) *	1986-10-29	1991-06-20	Binder Dieter	Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3-phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
AU2991595A (en) *	1994-08-03	1996-03-04	Fujisawa Pharmaceutical Co., Ltd.	Heterocyclic compound
SE9700661D0 (sv)	1997-02-25	1997-02-25	Astra Ab	New compounds

1996
- 1996-06-10 SE SE9602286A patent/SE9602286D0/xx unknown
1997
- 1997-05-06 UA UA98126867A patent/UA64714C2/uk unknown
- 1997-05-28 ZA ZA974681A patent/ZA974681B/xx unknown
- 1997-05-29 TW TW086107338A patent/TW470742B/zh active
- 1997-05-30 AR ARP970102342A patent/AR007352A1/es unknown
- 1997-06-05 CN CN97196704A patent/CN1101385C/zh not_active Expired - Fee Related
- 1997-06-05 BR BR9709666-0A patent/BR9709666A/pt not_active Application Discontinuation
- 1997-06-05 EP EP97927552A patent/EP0906288B1/en not_active Expired - Lifetime
- 1997-06-05 ES ES97927552T patent/ES2184097T3/es not_active Expired - Lifetime
- 1997-06-05 JP JP10501511A patent/JP2000512291A/ja not_active Ceased
- 1997-06-05 NZ NZ332965A patent/NZ332965A/xx unknown
- 1997-06-05 SK SK1654-98A patent/SK282704B6/sk unknown
- 1997-06-05 CA CA002256687A patent/CA2256687C/en not_active Expired - Fee Related
- 1997-06-05 RU RU99100397/04A patent/RU2184113C2/ru not_active IP Right Cessation
- 1997-06-05 HU HU0002952A patent/HUP0002952A3/hu unknown
- 1997-06-05 PT PT97927552T patent/PT906288E/pt unknown
- 1997-06-05 DE DE69716904T patent/DE69716904T2/de not_active Expired - Fee Related
- 1997-06-05 WO PCT/SE1997/000991 patent/WO1997047603A1/en active IP Right Grant
- 1997-06-05 EE EE9800430A patent/EE03682B1/et not_active IP Right Cessation
- 1997-06-05 AT AT97927552T patent/ATE227273T1/de not_active IP Right Cessation
- 1997-06-05 CZ CZ19984039A patent/CZ291469B6/cs not_active IP Right Cessation
- 1997-06-05 AU AU31992/97A patent/AU712173B2/en not_active Ceased
- 1997-06-05 DK DK97927552T patent/DK0906288T3/da active
- 1997-06-05 TR TR1998/02554T patent/TR199802554T2/xx unknown
- 1997-06-05 PL PL97330525A patent/PL330525A1/xx unknown
- 1997-06-05 US US08/875,132 patent/US6465505B1/en not_active Expired - Lifetime
- 1997-06-05 IL IL12743297A patent/IL127432A0/xx unknown
- 1997-06-05 ID IDP971913A patent/ID18431A/id unknown
- 1997-06-09 MY MYPI97002563A patent/MY119012A/en unknown
- 1997-09-24 SA SA97180427A patent/SA97180427B1/ar unknown
1998
- 1998-11-25 IS IS4907A patent/IS1864B/is unknown
- 1998-12-09 NO NO19985764A patent/NO311672B1/no unknown
1999
- 1999-05-31 HK HK99102417A patent/HK1017351A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0002952A3 (en)	2001-11-28
IS4907A (is)	1998-11-25
NO985764L (no)	1998-12-09
DE69716904D1 (de)	2002-12-12
RU2184113C2 (ru)	2002-06-27
EP0906288B1 (en)	2002-11-06
AU3199297A (en)	1998-01-07
ID18431A (id)	1998-04-09
ATE227273T1 (de)	2002-11-15
HK1017351A1 (en)	1999-11-19
SA97180427B1 (ar)	2005-10-15
US6465505B1 (en)	2002-10-15
ZA974681B (en)	1998-08-25
AR007352A1 (es)	1999-10-27
BR9709666A (pt)	2000-05-09
JP2000512291A (ja)	2000-09-19
ES2184097T3 (es)	2003-04-01
SK165498A3 (en)	1999-06-11
EE9800430A (et)	1999-06-15
NO985764D0 (no)	1998-12-09
EE03682B1 (et)	2002-04-15
IS1864B (is)	2003-04-15
NZ332965A (en)	2000-05-26
EP0906288A1 (en)	1999-04-07
SE9602286D0 (sv)	1996-06-10
PL330525A1 (en)	1999-05-24
TR199802554T2 (xx)	1999-03-22
TW470742B (en)	2002-01-01
DE69716904T2 (de)	2003-07-24
PT906288E (pt)	2003-02-28
CZ403998A3 (cs)	1999-05-12
CA2256687C (en)	2005-08-09
AU712173B2 (en)	1999-10-28
HUP0002952A2 (hu)	2001-05-28
CA2256687A1 (en)	1997-12-18
WO1997047603A1 (en)	1997-12-18
DK0906288T3 (da)	2003-01-06
CN1101385C (zh)	2003-02-12
MY119012A (en)	2005-03-31
UA64714C2 (en)	2004-03-15
SK282704B6 (sk)	2002-11-06
CZ291469B6 (cs)	2003-03-12
CN1226236A (zh)	1999-08-18
IL127432A0 (en)	1999-10-28

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RU2238271C2 (ru)	2004-10-20	Производные имидазопиридина, способы их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты, способ лечения желудочно-кишечных воспалительных заболеваний и способ лечения состояний, в которых вовлечено инфицирование h.pylori
RU2241000C2 (ru)	2004-11-27	Гетероциклические соединения с замещенной фенильной группировкой, способ их получения (варианты), фармацевтические препараты на их основе и способ ингибирования секреции желудочной кислоты
NO311672B1 (no)	2002-01-02	Nye forbindelser, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelser, og fremgangsmåter for deresfremstilling
SK109999A3 (en)	2000-01-18	Compounds for inhibition of gastric acid secretion
RU2294935C2 (ru)	2007-03-10	Имидазопиридиновые производные для применения в терапии в качестве лекарственного средства, ингибирующего протонный насос, и промежуточные соединения для их получения
EP1105390B1 (en)	2003-06-04	Imidazo[1,2-a]pyridine derivatives for the treatment of gastrointestinal diseases
KR100487029B1 (ko)	2005-11-25	신규화합물
MXPA00010231A (en)	2002-05-09	Imidazo pyridine derivatives which inhibit gastric acid secretion