NO308852B1 - Indol-2,3-dion-3-oksim-derivater, farmasøytisk blanding og anvendelse av forbindelsen - Google Patents
Indol-2,3-dion-3-oksim-derivater, farmasøytisk blanding og anvendelse av forbindelsenInfo
- Publication number
- NO308852B1 NO308852B1 NO970904A NO970904A NO308852B1 NO 308852 B1 NO308852 B1 NO 308852B1 NO 970904 A NO970904 A NO 970904A NO 970904 A NO970904 A NO 970904A NO 308852 B1 NO308852 B1 NO 308852B1
- Authority
- NO
- Norway
- Prior art keywords
- pct
- dione
- indole
- compound
- pharmaceutical composition
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- LNMAXZZQNSPQSR-UHFFFAOYSA-N 3-(hydroxyamino)indol-2-one Chemical class C1=CC=CC2=NC(=O)C(NO)=C21 LNMAXZZQNSPQSR-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK105394 | 1994-09-14 | ||
| PCT/EP1995/003593 WO1996008494A1 (en) | 1994-09-14 | 1995-09-12 | Indole-2,3-dione-3-oxime derivatives, their preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970904D0 NO970904D0 (no) | 1997-02-27 |
| NO970904L NO970904L (no) | 1997-04-24 |
| NO308852B1 true NO308852B1 (no) | 2000-11-06 |
Family
ID=8100455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO970904A NO308852B1 (no) | 1994-09-14 | 1997-02-27 | Indol-2,3-dion-3-oksim-derivater, farmasøytisk blanding og anvendelse av forbindelsen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5917053A (fi) |
| EP (1) | EP0781284B1 (fi) |
| JP (1) | JP3164371B2 (fi) |
| AT (1) | ATE188700T1 (fi) |
| AU (1) | AU687255B2 (fi) |
| CA (1) | CA2199613C (fi) |
| DE (1) | DE69514532T2 (fi) |
| EE (1) | EE03355B1 (fi) |
| FI (1) | FI112482B (fi) |
| NO (1) | NO308852B1 (fi) |
| NZ (1) | NZ293265A (fi) |
| WO (1) | WO1996008494A1 (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| DE69922936T2 (de) * | 1998-03-31 | 2005-12-08 | Neurosearch A/S | Verwendung von indol-2,3-dione-3-oximderivate als ampa-antagonisten |
| CA2369746A1 (en) | 1999-05-19 | 2000-11-30 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
| AU781067B2 (en) | 2000-01-24 | 2005-05-05 | Neurosearch A/S | Isatine derivatives with neurotrophic activity |
| WO2002064139A1 (en) * | 2001-02-15 | 2002-08-22 | Neurosearch A/S | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity |
| BR0211140A (pt) | 2001-07-13 | 2005-10-25 | Upjohn Co | Compostos e composições de indóis de hexaidroazepina (4, 5-g) e indolinas como ligantes de receptores 5-ht |
| US7718641B2 (en) | 2005-11-23 | 2010-05-18 | Aros Pharma Aps | Pyrrolo [3,4-H] isoquinoline compounds and methods for modulating gated ion channels |
| WO2008031831A2 (en) * | 2006-09-12 | 2008-03-20 | Neurosearch A/S | Pharmaceutical compositions comprising combinations of an ampa/kainate antagonistic compound and an inhibitor of a multidrug resistance protein |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
| CA2076948C (en) * | 1991-08-28 | 2002-04-16 | Frank Watjen | Isatineoxime derivatives, their preparation and use |
| AU680632B2 (en) * | 1992-10-13 | 1997-08-07 | Neurosearch A/S | Quinoxalinedione derivatives as EAA antagonists |
-
1995
- 1995-09-12 NZ NZ293265A patent/NZ293265A/en unknown
- 1995-09-12 CA CA002199613A patent/CA2199613C/en not_active Expired - Fee Related
- 1995-09-12 EP EP95932729A patent/EP0781284B1/en not_active Expired - Lifetime
- 1995-09-12 JP JP50990796A patent/JP3164371B2/ja not_active Expired - Fee Related
- 1995-09-12 WO PCT/EP1995/003593 patent/WO1996008494A1/en active IP Right Grant
- 1995-09-12 US US08/809,082 patent/US5917053A/en not_active Expired - Lifetime
- 1995-09-12 DE DE69514532T patent/DE69514532T2/de not_active Expired - Lifetime
- 1995-09-12 AU AU35664/95A patent/AU687255B2/en not_active Ceased
- 1995-09-12 AT AT95932729T patent/ATE188700T1/de not_active IP Right Cessation
- 1995-09-12 EE EE9700052A patent/EE03355B1/xx not_active IP Right Cessation
-
1997
- 1997-02-21 FI FI970750A patent/FI112482B/fi active
- 1997-02-27 NO NO970904A patent/NO308852B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996008494A1 (en) | 1996-03-21 |
| FI970750A0 (fi) | 1997-02-21 |
| FI112482B (fi) | 2003-12-15 |
| NZ293265A (en) | 1998-01-26 |
| FI970750L (fi) | 1997-03-13 |
| NO970904L (no) | 1997-04-24 |
| CA2199613A1 (en) | 1996-03-21 |
| AU687255B2 (en) | 1998-02-19 |
| EP0781284A1 (en) | 1997-07-02 |
| NO970904D0 (no) | 1997-02-27 |
| JPH09511524A (ja) | 1997-11-18 |
| CA2199613C (en) | 2000-02-29 |
| ATE188700T1 (de) | 2000-01-15 |
| US5917053A (en) | 1999-06-29 |
| AU3566495A (en) | 1996-03-29 |
| EP0781284B1 (en) | 2000-01-12 |
| DE69514532D1 (de) | 2000-02-17 |
| EE03355B1 (et) | 2001-02-15 |
| DE69514532T2 (de) | 2000-07-06 |
| JP3164371B2 (ja) | 2001-05-08 |
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