[go: up one dir, main page]

NO20074861L - Fremgangsmate for fremstilling av docetaxel - Google Patents

Fremgangsmate for fremstilling av docetaxel

Info

Publication number
NO20074861L
NO20074861L NO20074861A NO20074861A NO20074861L NO 20074861 L NO20074861 L NO 20074861L NO 20074861 A NO20074861 A NO 20074861A NO 20074861 A NO20074861 A NO 20074861A NO 20074861 L NO20074861 L NO 20074861L
Authority
NO
Norway
Prior art keywords
hydroxy groups
iii
positions
docetaxel
protected hydroxy
Prior art date
Application number
NO20074861A
Other languages
English (en)
Inventor
Antoine Paul Gaston Leze
Regis Perion
Original Assignee
Seripharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35106645&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20074861(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Seripharm filed Critical Seripharm
Publication of NO20074861L publication Critical patent/NO20074861L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Fremgangsmåte for fremstilling av docetaxel fra paclitaxel, hvori man utfører følgende trinn:. a) acetylering av paclitaxel. b) beskyttelse av de frie hydroksyfunksjonene henholdsvis i stilling -7,-10 og -2', c) avbenzoylering av amin i stilling -3' til et primæramin avledet fra 10-deacetylbaccatin, hvorav hydroksyfunksj onene i stilling -7, -10 og -2' er beskyttet, d) funksjonalisering av aminet ved et t-butoksykarbonylradikal for å oppnå et du docetaxelderivat med generell formel: hvori X representerer beskyttende radikaler eller hydrogenatomer, deretter eventuelt, e) frigjøring av hydroksyfunksj onene først beskyttet for å oppnå docetaxel.
NO20074861A 2005-02-24 2007-09-24 Fremgangsmate for fremstilling av docetaxel NO20074861L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0501882A FR2882363B1 (fr) 2005-02-24 2005-02-24 Procede de preparation du docetaxel
PCT/FR2006/000386 WO2006090056A1 (fr) 2005-02-24 2006-02-21 Procede de preparation du docetaxel

Publications (1)

Publication Number Publication Date
NO20074861L true NO20074861L (no) 2007-11-26

Family

ID=35106645

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074861A NO20074861L (no) 2005-02-24 2007-09-24 Fremgangsmate for fremstilling av docetaxel

Country Status (16)

Country Link
US (1) US20080200699A1 (no)
EP (1) EP1856080B1 (no)
JP (1) JP2008531527A (no)
KR (1) KR20070108188A (no)
CN (1) CN101128449A (no)
AT (1) ATE490245T1 (no)
AU (1) AU2006217803A1 (no)
BR (1) BRPI0607989A2 (no)
CA (1) CA2596696A1 (no)
DE (1) DE602006018584D1 (no)
FR (1) FR2882363B1 (no)
IL (1) IL185464A0 (no)
MX (1) MX2007010331A (no)
NO (1) NO20074861L (no)
RU (1) RU2007134454A (no)
WO (1) WO2006090056A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2914642B1 (fr) * 2007-04-03 2009-10-16 Seripharm Procede de preparation de taxanes 3'-n-substitues a partir du paclitaxel
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
CN103808851A (zh) * 2012-11-15 2014-05-21 刘胜远 一种红豆杉中10-去乙酰基紫杉醇的薄层色谱检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679807A (en) * 1995-01-30 1997-10-21 Hauser, Inc. Preparation of taxol and docetaxel through primary amines
US6891050B2 (en) * 2001-08-10 2005-05-10 Dabur India Limited Process for the preparation of taxanes such as paclitaxel, docetaxel and structurally similar analogs
DE60327651D1 (de) * 2002-10-09 2009-06-25 Chatham Biotec Ltd Thio-analoga von paclitaxel und deren vorprodukte

Also Published As

Publication number Publication date
WO2006090056A1 (fr) 2006-08-31
US20080200699A1 (en) 2008-08-21
CA2596696A1 (fr) 2006-08-31
CN101128449A (zh) 2008-02-20
DE602006018584D1 (de) 2011-01-13
BRPI0607989A2 (pt) 2009-10-27
AU2006217803A1 (en) 2006-08-31
JP2008531527A (ja) 2008-08-14
IL185464A0 (en) 2008-01-06
EP1856080A1 (fr) 2007-11-21
ATE490245T1 (de) 2010-12-15
KR20070108188A (ko) 2007-11-08
MX2007010331A (es) 2008-03-04
FR2882363B1 (fr) 2007-05-11
RU2007134454A (ru) 2009-03-27
EP1856080B1 (fr) 2010-12-01
FR2882363A1 (fr) 2006-08-25

Similar Documents

Publication Publication Date Title
WO2007118198A8 (en) 2-METHYLENE-1α,25-DIHYDROXY-19,21-DINORVITAMIN D3 ANALOGS AND USES THEREOF
WO2011018612A3 (en) Thiol protecting group
WO2008035207A3 (en) 2-methylene-1alpha-hydroxy-19,21-dinorvitamin d3 analogs and uses thereof
WO2008117796A1 (ja) 新規ムチリン誘導体
BR0306561A (pt) Processo para preparação de um sistema de camadas resistente a arranhões
CY1113176T1 (el) Παρασκευη ταξανων απο 9-διυδρο-13-ακετυλοβακκατινη iii
NO20074861L (no) Fremgangsmate for fremstilling av docetaxel
DE602005007504D1 (de) Eintopfsynthese von taxanderivaten und deren umwandlung in paclitaxel und docetaxel
ATE554774T1 (de) 2-methylen-19-nor-(20s-24epi)-1alpha,25- dihydrovitamin-d2
FR2907330B1 (fr) Dispositif de protection des berges d'incision.
BRPI0608015A2 (pt) processo para reparar o paclitaxel
HUP0202448A2 (hu) Eljárás paclitaxel C-4-metil-karbonát-analóg előállítására
NO20075195L (no) En fremgangsmate for rensingen av 10-deacetylbaccatin III fra 10-deacetyl-2-deabenzoyl-2-pentenoylbaccatin III
HUP9700991A2 (hu) Taxoidszármazékok és eljárás előállításukra
WO2006135692A3 (en) Processes for the preparation of docetaxel
EA201001738A1 (ru) Индолсульфонильные защитные группы, предназначенные для защиты гуанидиногрупп и аминогрупп
DE502004008550D1 (de) System und verfahren zum schutz von transportmitteln gegen ir-gelenkte flugkörper
WO2008125901A8 (en) 2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin d3 and uses thereof
WO2006084116A3 (en) Amine derivative containing compositions and methods for the treatment of viral infections related to the etiology of cancer
EP1827452A4 (en) 2-METHYLENE-19,21-DINOR-1alpha-HYDROXY-BISHOMOPREGNACALCIFEROL
WO2008035206A3 (en) 2-methylene-1 alpha-hydroxy-18,19,21-trinorvitamin d3 analogs and uses thereof
TW200510360A (en) Process for preparing 4-alkyl-or 4-aryl-oxycarbonyl paclitaxel analogs and novel intermediates
WO2006106244A3 (fr) PROCEDE DE PREPARATION DE β-AMINOESTERS OU α-, β-DIAMINOESTERS DERIVES DE LA SERINE

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application