NO20073797L - Humane monoklonale antistoffer mot prostata spesifikt membran antigen (PSMA) - Google Patents
Humane monoklonale antistoffer mot prostata spesifikt membran antigen (PSMA)Info
- Publication number
- NO20073797L NO20073797L NO20073797A NO20073797A NO20073797L NO 20073797 L NO20073797 L NO 20073797L NO 20073797 A NO20073797 A NO 20073797A NO 20073797 A NO20073797 A NO 20073797A NO 20073797 L NO20073797 L NO 20073797L
- Authority
- NO
- Norway
- Prior art keywords
- monoclonal antibodies
- psma
- human monoclonal
- antibodies
- antibodies against
- Prior art date
Links
- 102100041003 Glutamate carboxypeptidase 2 Human genes 0.000 title abstract 3
- 101000892862 Homo sapiens Glutamate carboxypeptidase 2 Proteins 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 229940127121 immunoconjugate Drugs 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001481 poly(stearyl methacrylate) Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SAMMENDRAG Foreliggende oppfinnelse tilveiebringer isolerte monoklonale antistoffer, spesielt humane monoklonale antistoffer, som spesifikt binder til PSMA med høy affinitet. Nukleinsyremolekyler som koder for antistoffene ifølge oppfinnelsen, ekspresjonsvektorer, vertsceller og fremgangsmåter for å uttrykke antistoffene ifølge oppfinnelsen tilveiebringes også. Immunokonjugater, bispesifikke molekyler og farmasøytiske blandinger omfattende antistoffene ifølge oppfinnelsen er også gitt. Oppfinnelsen tilveiebringer også fremgangsmåter for behandling av kreft.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65412505P | 2005-02-18 | 2005-02-18 | |
| US72049905P | 2005-09-26 | 2005-09-26 | |
| US74841705P | 2005-12-08 | 2005-12-08 | |
| PCT/US2006/005852 WO2006089230A2 (en) | 2005-02-18 | 2006-02-17 | Human monoclonal antibodies to prostate specific membrane antigen (psma) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20073797L true NO20073797L (no) | 2007-09-12 |
Family
ID=36658707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20073797A NO20073797L (no) | 2005-02-18 | 2007-07-20 | Humane monoklonale antistoffer mot prostata spesifikt membran antigen (PSMA) |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090297438A1 (no) |
| EP (1) | EP1851250B1 (no) |
| JP (1) | JP2008529556A (no) |
| KR (1) | KR20070115967A (no) |
| CN (1) | CN101124249B (no) |
| AU (1) | AU2006214031A1 (no) |
| BR (1) | BRPI0607757A2 (no) |
| CA (1) | CA2598522A1 (no) |
| CY (1) | CY1113089T1 (no) |
| DK (1) | DK1851250T3 (no) |
| ES (1) | ES2386366T3 (no) |
| HR (1) | HRP20120709T1 (no) |
| IL (1) | IL184733A (no) |
| MX (1) | MX2007009878A (no) |
| NO (1) | NO20073797L (no) |
| NZ (1) | NZ556661A (no) |
| PL (1) | PL1851250T3 (no) |
| PT (1) | PT1851250E (no) |
| WO (1) | WO2006089230A2 (no) |
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| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
| DE102008010363A1 (de) * | 2008-02-18 | 2009-08-20 | Lang, Florian, Prof. Dr.med. | Sgk1 als therapeutisches und diagnostisches Target für karzinomatöse Erkrankungen |
| CA2721169A1 (en) * | 2008-04-14 | 2009-10-22 | Proscan Rx Pharma Inc. | Prostate specific membrane antigen antibodies and antigen binding fragments |
| DK2326350T3 (da) | 2008-09-08 | 2013-12-16 | Psma Dev Company L L C | Forbindelser til at dræbe psma-udtrykkende, taxanresistente cancerceller |
| WO2010037837A2 (en) | 2008-10-01 | 2010-04-08 | Micromet Ag | Bispecific single chain antibodies with specificity for high molecular weight target antigens |
| JP6126782B2 (ja) * | 2008-10-01 | 2017-05-10 | アムゲン リサーチ (ミュンヘン) ゲーエムベーハー | 異種間特異的psma×cd3二重特異性単鎖抗体 |
| CN101891818B (zh) * | 2009-01-16 | 2012-07-25 | 中国人民解放军第四军医大学 | 抗人前列腺特异性膜抗原胞外区单链抗体及其应用 |
| EP2419451A4 (en) * | 2009-04-14 | 2012-11-14 | Proscan Rx Pharma Inc | ANTIBODIES DIRECTED AGAINST THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN |
| EA201290020A1 (ru) | 2009-05-19 | 2013-10-30 | ЭйАйСи БЛЭБ КОМПАНИ | Композитный токоприемник и способы его изготовления |
| US8394922B2 (en) | 2009-08-03 | 2013-03-12 | Medarex, Inc. | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof |
| TWI629357B (zh) * | 2009-10-02 | 2018-07-11 | 安進研究(慕尼黑)有限責任公司 | 跨物種特異性的PSMAxCD3雙特異性單鏈抗體 |
| TWI653333B (zh) | 2010-04-01 | 2019-03-11 | 安進研究(慕尼黑)有限責任公司 | 跨物種專一性之PSMAxCD3雙專一性單鏈抗體 |
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-
2006
- 2006-02-17 PL PL06735489T patent/PL1851250T3/pl unknown
- 2006-02-17 MX MX2007009878A patent/MX2007009878A/es not_active Application Discontinuation
- 2006-02-17 JP JP2007556368A patent/JP2008529556A/ja active Pending
- 2006-02-17 ES ES06735489T patent/ES2386366T3/es not_active Expired - Lifetime
- 2006-02-17 HR HRP20120709TT patent/HRP20120709T1/hr unknown
- 2006-02-17 BR BRPI0607757-9A patent/BRPI0607757A2/pt not_active Application Discontinuation
- 2006-02-17 NZ NZ556661A patent/NZ556661A/en not_active IP Right Cessation
- 2006-02-17 US US11/918,153 patent/US20090297438A1/en not_active Abandoned
- 2006-02-17 WO PCT/US2006/005852 patent/WO2006089230A2/en not_active Ceased
- 2006-02-17 KR KR1020077021333A patent/KR20070115967A/ko not_active Withdrawn
- 2006-02-17 EP EP06735489A patent/EP1851250B1/en not_active Expired - Lifetime
- 2006-02-17 CN CN2006800053479A patent/CN101124249B/zh not_active Expired - Fee Related
- 2006-02-17 AU AU2006214031A patent/AU2006214031A1/en not_active Abandoned
- 2006-02-17 PT PT06735489T patent/PT1851250E/pt unknown
- 2006-02-17 CA CA002598522A patent/CA2598522A1/en not_active Abandoned
- 2006-02-17 DK DK06735489.4T patent/DK1851250T3/da active
-
2007
- 2007-07-19 IL IL184733A patent/IL184733A/en not_active IP Right Cessation
- 2007-07-20 NO NO20073797A patent/NO20073797L/no not_active Application Discontinuation
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Also Published As
| Publication number | Publication date |
|---|---|
| PT1851250E (pt) | 2012-08-27 |
| CY1113089T1 (el) | 2016-04-13 |
| MX2007009878A (es) | 2007-10-03 |
| EP1851250B1 (en) | 2012-06-06 |
| AU2006214031A1 (en) | 2006-08-24 |
| KR20070115967A (ko) | 2007-12-06 |
| PL1851250T3 (pl) | 2012-10-31 |
| DK1851250T3 (da) | 2012-07-09 |
| BRPI0607757A2 (pt) | 2009-10-06 |
| IL184733A0 (en) | 2007-12-03 |
| WO2006089230A3 (en) | 2006-11-16 |
| CN101124249B (zh) | 2011-06-29 |
| HRP20120709T1 (hr) | 2012-10-31 |
| NZ556661A (en) | 2010-10-29 |
| EP1851250A2 (en) | 2007-11-07 |
| JP2008529556A (ja) | 2008-08-07 |
| IL184733A (en) | 2015-07-30 |
| CA2598522A1 (en) | 2006-08-24 |
| WO2006089230A2 (en) | 2006-08-24 |
| ES2386366T3 (es) | 2012-08-17 |
| US20090297438A1 (en) | 2009-12-03 |
| CN101124249A (zh) | 2008-02-13 |
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| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
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