[go: up one dir, main page]

NO20064732L - Alfa-aminoamidderivater nyttige i behandlingen av urolige bein-syndromet og additive lidelser - Google Patents

Alfa-aminoamidderivater nyttige i behandlingen av urolige bein-syndromet og additive lidelser

Info

Publication number
NO20064732L
NO20064732L NO20064732A NO20064732A NO20064732L NO 20064732 L NO20064732 L NO 20064732L NO 20064732 A NO20064732 A NO 20064732A NO 20064732 A NO20064732 A NO 20064732A NO 20064732 L NO20064732 L NO 20064732L
Authority
NO
Norway
Prior art keywords
treatment
troubled
alpha
useful
aminoamide derivatives
Prior art date
Application number
NO20064732A
Other languages
English (en)
Other versions
NO337900B1 (no
Inventor
Elena Barbanti
Florian Thaler
Patricia Salvati
Claudia Besana
Emanuela Izzo
Ruggero Fariello
Luca Benati
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of NO20064732L publication Critical patent/NO20064732L/no
Publication of NO337900B1 publication Critical patent/NO337900B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Oppfinnelsen vedrører anvendelsen av visse a-aminoamidderivater med formel (I) i behandlingen av RLS og addiktive forstyrrelser. Forbindelsene ifølge denne oppfinnelsen er i stand til å redusere eller til og med stoppe symptomene RLS og addiktive forstyrrelser vesentlig uten bivirkninger.
NO20064732A 2004-04-22 2006-10-19 Anvendelse av alfa-aminoamidderivater for fremstilling av medikamenter til urolige bein-syndromet NO337900B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04009532A EP1588704A1 (en) 2004-04-22 2004-04-22 Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
PCT/EP2005/004166 WO2005102300A1 (en) 2004-04-22 2005-04-19 α-AMINOAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF RESTLESS LEGS SYNDROME AND ADDICTIVE DISORDERS

Publications (2)

Publication Number Publication Date
NO20064732L true NO20064732L (no) 2006-11-22
NO337900B1 NO337900B1 (no) 2016-07-04

Family

ID=34924693

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20064732A NO337900B1 (no) 2004-04-22 2006-10-19 Anvendelse av alfa-aminoamidderivater for fremstilling av medikamenter til urolige bein-syndromet
NO20150971A NO338870B1 (no) 2004-04-22 2015-07-27 Alfa-aminoamidderivater nyttige i behandlingen av addiktive forstyrrelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20150971A NO338870B1 (no) 2004-04-22 2015-07-27 Alfa-aminoamidderivater nyttige i behandlingen av addiktive forstyrrelser

Country Status (26)

Country Link
US (2) US8445513B2 (no)
EP (3) EP1588704A1 (no)
JP (1) JP5020069B2 (no)
KR (2) KR101195819B1 (no)
CN (1) CN1942179B (no)
AT (2) ATE405256T1 (no)
AU (1) AU2005235428B2 (no)
BR (2) BR122020004541B1 (no)
CA (1) CA2563674C (no)
CY (2) CY1108494T1 (no)
DE (2) DE602005009162D1 (no)
DK (2) DK1737438T3 (no)
ES (2) ES2313330T3 (no)
HK (1) HK1099216A1 (no)
HR (2) HRP20080593T3 (no)
IL (1) IL178732A (no)
ME (2) ME01219B (no)
MX (1) MXPA06012163A (no)
NO (2) NO337900B1 (no)
NZ (1) NZ550664A (no)
PL (2) PL1737438T3 (no)
PT (2) PT1900362E (no)
RS (2) RS51791B (no)
RU (1) RU2403030C2 (no)
SI (2) SI1737438T1 (no)
WO (1) WO2005102300A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
BRPI0212298B8 (pt) * 2001-09-03 2021-05-25 Newron Pharm Spa composição farmacêutica compreendendo gabapentina ou um análogo da mesma e (alfa)-aminoamida e seu uso analgésico
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
RU2396251C2 (ru) * 2003-08-25 2010-08-10 Ньюрон Фармасьютикалс, Спа Производные альфа-аминоамидов, применимые в качестве противовоспалительных агентов
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
AU2005282028B2 (en) * 2004-09-10 2011-03-24 Newron Pharmaceuticals S.P.A. (halobenzyloxy) benzylamino-propanamides as sodium and/or calcium channel selective modulators
US20060173074A1 (en) * 2004-11-10 2006-08-03 Juha Ellmen Treatment of restless legs syndrome
SI1963280T1 (sl) 2005-12-22 2016-02-29 Newron Pharmaceuticals S.P.A. 2-feniletilamino derivati kot modulatorji kalcijevih in/ali natrijevih kanalčkov
NZ571591A (en) * 2006-04-03 2011-09-30 Teva Pharma Use of rasagiline for the treatment of restless legs syndrome
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
EA025326B1 (ru) * 2006-06-19 2016-12-30 Ньюрон Фармасьютикалс С.П.А. Применение сафинамида и ралфинамида высокой степени чистоты для лечения заболеваний и болезненных состояний в условиях, не препятствующих активности цитохромов системы cyp450 и не проявляющих блокирующих свойств в отношении herg канала
GB0706630D0 (en) * 2007-04-04 2007-05-16 Glaxo Group Ltd Novel compounds
US8519000B2 (en) 2007-06-15 2013-08-27 Newron Pharmaceuticals S.P.A. Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
US8530701B2 (en) 2007-12-11 2013-09-10 Newron Pharmaceuticals, S.P.A. High purity 2-[4-(3- OR 2-fluorobenzyloxy)benzylamino]propanamides and methods of use thereof
JP5736175B2 (ja) * 2007-12-19 2015-06-17 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー 精神障害の治療に有用なα−アミノアミド誘導体
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
KR101851118B1 (ko) 2010-04-27 2018-04-23 뉴론 파마슈티칼즈 에스. 피. 에이. 랄핀아미드 메탄설포네이트 염들 또는 이들의 ｒ―에난티오머들의 제조 방법
US11278651B2 (en) * 2018-10-17 2022-03-22 Gambro Lundia Ab Membrane and device for treating restless leg syndrome
CN114667963B (zh) * 2020-12-24 2024-04-26 中国科学院脑科学与智能技术卓越创新中心 一种非人灵长类动物药物成瘾性评估的装置

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US4049663A (en) * 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4935429A (en) * 1985-10-25 1990-06-19 Dackis Charles A Method of treating psychostimulant addiction
EP0331620B1 (de) * 1988-03-01 1993-08-11 Birkmayer, Walther, Prof. Dr. Mittel zur Behandlung des Parkinson-Syndroms
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
EP0520325A1 (de) * 1991-06-28 1992-12-30 F.Hoffmann-La Roche & Co. Aktiengesellschaft Verwendung von Monoaminoxidase-B-Hemmern zur Verhütung und Behandlung von Entzugserscheinungen nach Alkohol- und Drogenmissbrauch
GB9306886D0 (en) 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
IL111240A (en) * 1993-10-18 2001-10-31 Teva Pharma Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
JPH11505828A (ja) * 1995-05-26 1999-05-25 ファイザー・インコーポレーテッド パーキンソン症候群の治療用の選択的ｎｍｄａアンタゴニスト含有組合せ
WO1997000511A1 (de) 1995-06-17 1997-01-03 Baumann Guenter Scheibenkörper
GB9515411D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa N-(4-substituted-benzyl)-2-aminolactam derivatives
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
GB9727521D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Substituted 2-benzylamino-2-phenyl-acetamide compounds
WO1999035215A2 (en) 1998-01-12 1999-07-15 Deborah Wenzel An additive composition also used as a fuel composition comprising water soluble alcohols
FI109453B (fi) * 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
WO2001034172A2 (en) * 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome
AU2080201A (en) 1999-12-10 2001-06-18 University Of Cincinnati, The Treatment of addiction disorders
US20020019421A1 (en) * 2000-07-05 2002-02-14 Roni Biberman Compositions and therapy for substance addiction
WO2002100350A2 (en) * 2001-06-13 2002-12-19 The Regents Of University Of Michigan Dopamine receptor ligands and therapeutic methods based thereon
ES2324214T3 (es) * 2002-05-29 2009-08-03 F. Hoffmann-La Roche Ag Derivados de n-acilaminobenceno como inhibidores de la monoamina oxidasa b selectiva.
EP1515921B1 (en) 2002-06-24 2006-03-08 Rockwool International A/S Process and apparatus for controlling mineral wool production using a cascade rotor
US6900354B2 (en) * 2002-07-15 2005-05-31 Hoffman-La Roche Inc. 3-phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives
AR044007A1 (es) 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
JP2005060370A (ja) * 2003-07-25 2005-03-10 Kyowa Hakko Kogyo Co Ltd 医薬組成物
EP1524267A1 (en) 2003-10-15 2005-04-20 Newron Pharmaceuticals S.p.A. Substituted benzylaminoalkylene heterocycles
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders

Also Published As

Publication number Publication date
PT1737438E (pt) 2008-12-22
KR20120028399A (ko) 2012-03-22
HRP20080593T3 (en) 2008-12-31
NO20150971L (no) 2006-11-22
ES2357559T3 (es) 2011-04-27
SI1737438T1 (sl) 2008-12-31
CY1108494T1 (el) 2014-04-09
US8445513B2 (en) 2013-05-21
EP1900362A2 (en) 2008-03-19
EP1737438A1 (en) 2007-01-03
NO338870B1 (no) 2016-10-31
AU2005235428B2 (en) 2010-03-18
WO2005102300A1 (en) 2005-11-03
MXPA06012163A (es) 2007-01-17
CN1942179A (zh) 2007-04-04
US20070203182A1 (en) 2007-08-30
EP1900362B1 (en) 2011-01-12
CN1942179B (zh) 2010-08-11
KR101195819B1 (ko) 2012-11-05
ATE405256T1 (de) 2008-09-15
JP2007533691A (ja) 2007-11-22
JP5020069B2 (ja) 2012-09-05
ES2313330T3 (es) 2009-03-01
HK1099216A1 (en) 2007-08-10
BR122020004541B1 (pt) 2021-11-09
BRPI0509976B8 (pt) 2021-05-25
NO337900B1 (no) 2016-07-04
EP1737438B1 (en) 2008-08-20
PL1737438T3 (pl) 2009-01-30
CA2563674C (en) 2012-12-18
AU2005235428A1 (en) 2005-11-03
US20130217747A1 (en) 2013-08-22
KR20070042914A (ko) 2007-04-24
PT1900362E (pt) 2011-03-09
IL178732A0 (en) 2007-05-15
CA2563674A1 (en) 2005-11-03
IL178732A (en) 2013-01-31
KR101238377B1 (ko) 2013-03-04
BRPI0509976A (pt) 2007-10-16
EP1900362A3 (en) 2009-04-01
SI1900362T1 (sl) 2011-03-31
ME01219B (me) 2013-06-20
DK1737438T3 (da) 2008-12-08
DK1900362T3 (da) 2011-05-09
EP1588704A1 (en) 2005-10-26
BRPI0509976B1 (pt) 2020-10-06
NZ550664A (en) 2010-08-27
PL1900362T3 (pl) 2011-06-30
RU2403030C2 (ru) 2010-11-10
DE602005025941D1 (de) 2011-02-24
RS50667B (sr) 2010-06-30
RS51791B (en) 2011-12-31
DE602005009162D1 (de) 2008-10-02
ME02324B (me) 2016-06-20
CY1111656T1 (el) 2015-10-07
RU2006137079A (ru) 2008-04-27
HRP20110230T1 (hr) 2011-04-30
ATE494890T1 (de) 2011-01-15
US8697738B2 (en) 2014-04-15

Similar Documents

Publication Publication Date Title
NO20064732L (no) Alfa-aminoamidderivater nyttige i behandlingen av urolige bein-syndromet og additive lidelser
NO20070049L (no) Pyrrolotriazinderivater anvendelig for behandling av hyperproliferative forstyrrelser og sykdommer assosiert med angiogenese
NO20060424L (no) 5-heteroringbaserte P38 kinaseinhibitorer
DE602004022668D1 (de) 5-gliedrige heterocyclische p-38 inhibitoren
NO20075099L (no) Alkynyl-pyrrolopyrmidiner og relaterte analoger som HSP90-inhibitorer
ATE457313T1 (de) Bicyclische heterocyclische p-38-kinase- inhibitoren
NO20074941L (no) Anvendelse av diosmetinforbindelser i behandlingen og forebyggingen av trombotiske patologier
NO20065260L (no) Tri(cyklo)substituerte amidforbindelser
NO20082594L (no) Pyrimidinylbenzotiofenforbindelser
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
NO20076515L (no) Hydantoinforbindelser
NO20053792L (no) Heterocykly-3-sulfonylindazoler som 5-hydroksytryptamin-6 ligander
NO20053111L (no) Peptider som inhiberer angiogenese, cellemigrering, celleinvasjon og celleproliferering.
NO20080354L (no) Benzofuranylderivater som 5-HT6-reseptorinhibitorer
NO20072078L (no) Indolderivater som inhibitorer av loselig adenylsyklase
NO20071466L (no) 3-substituerte-5- og 6-aminoalkyl indol-2-karboksylsyreamider og relaterte analoger som inhibitorer av kaseinkinase IE
GB0407025D0 (en) Novel compounds
NO20070065L (no) Indolyalkylaminmetabolitter som 5-hydroksytrytamin-6 ligander
SE0301905D0 (sv) Novel imidazopyridine compound I with therapeutic effect
MY140718A (en) Novel imidazopyridine compound ii with therapeutic effect
SE0301903D0 (sv) Novel imidazopyridine compound III with therapeutic effect
NO20070058L (no) Amino-halogen-imidazopyridiner som protonpumpeinhibitorer
NO20071685L (no) Tricykliske adamantylamidderivater som 11-beta hydroksysteroid-dehydrogenaseinhibitorer