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NO20056091L - Nye benzo[b]pyrano[3,2-h]akridin-7-on-cinnamatforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem - Google Patents

Nye benzo[b]pyrano[3,2-h]akridin-7-on-cinnamatforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Info

Publication number
NO20056091L
NO20056091L NO20056091A NO20056091A NO20056091L NO 20056091 L NO20056091 L NO 20056091L NO 20056091 A NO20056091 A NO 20056091A NO 20056091 A NO20056091 A NO 20056091A NO 20056091 L NO20056091 L NO 20056091L
Authority
NO
Norway
Prior art keywords
alkyl
aryl
optionally substituted
halo
acridin
Prior art date
Application number
NO20056091A
Other languages
English (en)
Inventor
Michel Koch
Alain Pierre
Sylvie Michel
John Hickman
Laurence Kraus-Berthier
Stephane Leonce
Bruno Pfeiffer
Francois Tillequin
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20056091L publication Critical patent/NO20056091L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Forbindelse med formel (I):. hvori:. X og Y hver representerer en gruppe valgt fra hydrogen, halogen, alkoksy, nitro, cyano, alkyl, alkenyl, polyhaloalkyl og -NRRhvori Ra og Rer som definert i beskrivelsen, Z representerer et oksygenatom eller NRhvori Rer som definert i beskrivelsen, Ar representerer aryl eller heteroaryl, Ri representerer et hydrogenatom eller en alkylgnippe, Rrepresenterer en gruppe valgt fra et hydrogenatom, alkyl, -ORog -NRR, hvori Ra og R, er som definert i beskrivelsen, Rog Rrepresenterer et hydrogenatom eller en alkylgnippe, Rrepresenterer et hydrogenatom eller en gruppe med formel OR;, NRR, Wi-C(W)-U-V, Wi-Crø-W-Teller Z-CO-CH=CHAr hvori R,, Ri, Wi, W, W, U, V, T, Z og Ar er som definert i beskrivelsen, deres isomerer, og også addisjonssalter derav med en farmasøytisk akseptabel syre eller base. Medikamenter.
NO20056091A 2004-12-22 2005-12-21 Nye benzo[b]pyrano[3,2-h]akridin-7-on-cinnamatforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem NO20056091L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0413682A FR2879600B1 (fr) 2004-12-22 2004-12-22 Nouveaux derives cinnamates de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
NO20056091L true NO20056091L (no) 2006-06-23

Family

ID=34954114

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20056091A NO20056091L (no) 2004-12-22 2005-12-21 Nye benzo[b]pyrano[3,2-h]akridin-7-on-cinnamatforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Country Status (26)

Country Link
US (1) US7144891B2 (no)
EP (1) EP1674101B1 (no)
JP (1) JP2006176525A (no)
KR (1) KR100742060B1 (no)
CN (1) CN1796387A (no)
AT (1) ATE378050T1 (no)
AU (1) AU2005247032A1 (no)
BR (1) BRPI0506019A (no)
CA (1) CA2529630A1 (no)
CY (1) CY1107100T1 (no)
DE (1) DE602005003315T2 (no)
DK (1) DK1674101T3 (no)
EA (1) EA010094B1 (no)
ES (1) ES2297648T3 (no)
FR (1) FR2879600B1 (no)
HR (1) HRP20070524T3 (no)
MA (1) MA27965A1 (no)
MX (1) MXPA05013993A (no)
MY (1) MY138045A (no)
NO (1) NO20056091L (no)
NZ (1) NZ544315A (no)
PL (1) PL1674101T3 (no)
PT (1) PT1674101E (no)
SG (1) SG123675A1 (no)
SI (1) SI1674101T1 (no)
ZA (1) ZA200510323B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902792A1 (fr) * 2006-06-21 2007-12-28 Servier Lab Nouveaux derives cinnamates de tetrahydro-7h-pyrano(2,3-c)acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2772765B1 (fr) * 1997-12-19 2000-03-17 Adir Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795071B1 (fr) * 1999-06-16 2001-07-27 Adir Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2827864B1 (fr) * 2001-07-25 2005-09-16 Servier Lab Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7056929B2 (en) * 2001-07-25 2006-06-06 Les Laboratoires Servier Benzo[b]pyrano[3,2-h]acridin-7-one compounds

Also Published As

Publication number Publication date
US7144891B2 (en) 2006-12-05
FR2879600B1 (fr) 2007-02-09
SG123675A1 (en) 2006-07-26
EA200501845A2 (ru) 2006-06-30
DE602005003315T2 (de) 2008-09-25
NZ544315A (en) 2006-11-30
DE602005003315D1 (de) 2007-12-27
EP1674101A1 (fr) 2006-06-28
PL1674101T3 (pl) 2008-05-30
JP2006176525A (ja) 2006-07-06
DK1674101T3 (da) 2008-03-03
MY138045A (en) 2009-04-30
FR2879600A1 (fr) 2006-06-23
MXPA05013993A (es) 2006-06-21
BRPI0506019A (pt) 2006-09-19
CA2529630A1 (fr) 2006-06-22
EA010094B1 (ru) 2008-06-30
US20060135545A1 (en) 2006-06-22
ATE378050T1 (de) 2007-11-15
CN1796387A (zh) 2006-07-05
PT1674101E (pt) 2007-12-17
EA200501845A3 (ru) 2006-10-27
ES2297648T3 (es) 2008-05-01
HRP20070524T3 (en) 2008-07-31
CY1107100T1 (el) 2012-10-24
ZA200510323B (en) 2006-12-27
MA27965A1 (fr) 2006-07-03
KR20060072093A (ko) 2006-06-27
AU2005247032A1 (en) 2006-07-06
EP1674101B1 (fr) 2007-11-14
KR100742060B1 (ko) 2007-07-23
SI1674101T1 (sl) 2008-04-30

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