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NO20044881L - Acyl-3-carboxyphenylurea derivatives, preparation method and use thereof - Google Patents

Acyl-3-carboxyphenylurea derivatives, preparation method and use thereof

Info

Publication number
NO20044881L
NO20044881L NO20044881A NO20044881A NO20044881L NO 20044881 L NO20044881 L NO 20044881L NO 20044881 A NO20044881 A NO 20044881A NO 20044881 A NO20044881 A NO 20044881A NO 20044881 L NO20044881 L NO 20044881L
Authority
NO
Norway
Prior art keywords
acyl
preparation
derivatives
well
acceptable salts
Prior art date
Application number
NO20044881A
Other languages
Norwegian (no)
Inventor
Alfons Enhsen
Andreas Herling
Elisabeth Defossa
Karl Schoenafinger
Thomas Klabunde
Karl-Ulrich Wendt
Dieter Kadereit
Hans-Joerg Burger
Erich Von Rodern
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20044881L publication Critical patent/NO20044881L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Oppfinnelsen vedrører acyl-3-karboksyfenyl-ureaderivater så vel som deres fysiologisk akseptable salter og fysiologisk funksjonelle derivater. Oppfinnelsen vedrører forbindelsen med formel (I), hvor restene har den angitte betydningen, så vel som deres fysiologisk akseptable salter og fremgangsmåte for deres fremstilling. Forbindelsene egner seg for eksempel som anti-diabetika.The invention relates to acyl-3-carboxyphenyl urea derivatives as well as their physiologically acceptable salts and physiologically functional derivatives. The invention relates to the compound of formula (I), wherein the residues have the indicated meaning, as well as their physiologically acceptable salts and process for their preparation. The compounds are suitable, for example, as anti-diabetics.

NO20044881A 2002-04-11 2004-11-09 Acyl-3-carboxyphenylurea derivatives, preparation method and use thereof NO20044881L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10215908A DE10215908B4 (en) 2002-04-11 2002-04-11 Acyl-3-carboxyphenyl-urea derivatives and their use as medicaments
PCT/EP2003/003254 WO2003084923A1 (en) 2002-04-11 2003-03-28 Acyl-3-carboxyphenylurea derivatives, method for production and use thereof

Publications (1)

Publication Number Publication Date
NO20044881L true NO20044881L (en) 2005-01-07

Family

ID=28684936

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044881A NO20044881L (en) 2002-04-11 2004-11-09 Acyl-3-carboxyphenylurea derivatives, preparation method and use thereof

Country Status (24)

Country Link
EP (1) EP1497263B1 (en)
JP (1) JP4328212B2 (en)
KR (1) KR20040097332A (en)
CN (1) CN1263734C (en)
AR (1) AR039402A1 (en)
AT (1) ATE404532T1 (en)
AU (1) AU2003232192A1 (en)
BR (1) BR0309130A (en)
CA (1) CA2481819A1 (en)
DE (2) DE10215908B4 (en)
HK (1) HK1075650A1 (en)
HR (1) HRP20040931A2 (en)
HU (1) HUP0500203A2 (en)
IL (1) IL164248A0 (en)
MA (1) MA27195A1 (en)
MX (1) MXPA04009239A (en)
NO (1) NO20044881L (en)
NZ (1) NZ535833A (en)
PL (1) PL371317A1 (en)
RS (1) RS88704A (en)
RU (1) RU2004133046A (en)
TW (1) TW200401765A (en)
WO (1) WO2003084923A1 (en)
ZA (1) ZA200407361B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10215907A1 (en) * 2002-04-11 2003-11-06 Aventis Pharma Gmbh Acyl-4-carboxyphenyl-urea derivatives, processes for their preparation and their use
DE10306502B4 (en) * 2003-02-17 2005-03-17 Aventis Pharma Deutschland Gmbh Substituted 3- (benzoylureido) thiophene derivatives and medicaments containing them
DE10308351A1 (en) 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituted cycloalkyl derivatives having acidic, usually heterocyclic groups, processes for their preparation and their use as medicaments
DE10308355A1 (en) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl-substituted alkanoic acid derivatives, process for their preparation and their use as medicaments
DE10308352A1 (en) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Branched side chain arylcycloalkyl derivatives, process for their preparation and their use as medicaments
DE10308353A1 (en) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkyl derivatives, processes for their preparation and their use as medicines
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
EP1586573B1 (en) 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolones, processes for their preparation and their use as pharmaceuticals
DE102005026762A1 (en) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-one derivatives as inhibitors of lipases and phospholipases
PE20110235A1 (en) 2006-05-04 2011-04-14 Boehringer Ingelheim Int PHARMACEUTICAL COMBINATIONS INCLUDING LINAGLIPTIN AND METMORPHINE

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62111961A (en) * 1985-09-30 1987-05-22 ユニオン・カ−バイド・コ−ポレ−シヨン Insecticidal 1-(4-aryloxyphenyl)-3-benzoyl urea compound andits production
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
ATE205477T1 (en) * 1995-06-06 2001-09-15 Pfizer SUBSTITUTED N-(INDOLE-2-CARBONYL)-AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS
AU3772800A (en) * 1999-03-24 2000-10-09 Sepracor, Inc. Diaryl thioethers, compositions and uses thereof
UY26615A1 (en) * 2000-03-16 2001-10-25 Pfizer Prod Inc GLUCOGEN PHOSPHORYLASE INHIBITOR.
KR20030007934A (en) * 2000-06-09 2003-01-23 아벤티스 파마 도이칠란트 게엠베하 Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
GB0021831D0 (en) * 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds
PE20021091A1 (en) * 2001-05-25 2003-02-04 Aventis Pharma Gmbh DERIVATIVES OF PHENYLUREA SUBSTITUTED WITH CARBONAMIDE AND PROCEDURE FOR THEIR PREPARATION

Also Published As

Publication number Publication date
ZA200407361B (en) 2006-02-22
WO2003084923A1 (en) 2003-10-16
RS88704A (en) 2007-02-05
EP1497263A1 (en) 2005-01-19
ATE404532T1 (en) 2008-08-15
BR0309130A (en) 2005-02-01
CA2481819A1 (en) 2003-10-16
JP2005522481A (en) 2005-07-28
CN1646486A (en) 2005-07-27
EP1497263B1 (en) 2008-08-13
NZ535833A (en) 2006-03-31
DE10215908A1 (en) 2003-11-06
HK1075650A1 (en) 2005-12-23
MXPA04009239A (en) 2005-01-25
DE10215908B4 (en) 2005-08-18
KR20040097332A (en) 2004-11-17
AR039402A1 (en) 2005-02-16
HUP0500203A2 (en) 2005-06-28
CN1263734C (en) 2006-07-12
TW200401765A (en) 2004-02-01
JP4328212B2 (en) 2009-09-09
HRP20040931A2 (en) 2005-02-28
RU2004133046A (en) 2005-04-20
AU2003232192A1 (en) 2003-10-20
IL164248A0 (en) 2005-12-18
PL371317A1 (en) 2005-06-13
DE50310320D1 (en) 2008-09-25
MA27195A1 (en) 2005-01-03

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