NO20063859L - Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and use thereof as medicaments - Google Patents
Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and use thereof as medicamentsInfo
- Publication number
- NO20063859L NO20063859L NO20063859A NO20063859A NO20063859L NO 20063859 L NO20063859 L NO 20063859L NO 20063859 A NO20063859 A NO 20063859A NO 20063859 A NO20063859 A NO 20063859A NO 20063859 L NO20063859 L NO 20063859L
- Authority
- NO
- Norway
- Prior art keywords
- quinolone
- medicaments
- amino
- carboxylic acid
- acid derivatives
- Prior art date
Links
- CVSYGPGKZKCLHQ-UHFFFAOYSA-N 7-amino-4-oxo-3h-quinoline-3-carboxylic acid Chemical class O=C1C(C(O)=O)C=NC2=CC(N)=CC=C21 CVSYGPGKZKCLHQ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives as well as their physiologically compatible salts and physiologically functional derivatives. The invention concerns compounds of formula (I), wherein the radicals have the cited meanings, and the physiologically compatible salts thereof. The compounds are suited for use, e.g. as medicaments for preventing and treating type 2 diabetes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004004971A DE102004004971B3 (en) | 2004-01-31 | 2004-01-31 | Cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as Arnzeimittel |
PCT/EP2005/000373 WO2005073231A1 (en) | 2004-01-31 | 2005-01-15 | Cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20063859L true NO20063859L (en) | 2006-08-29 |
Family
ID=34813070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20063859A NO20063859L (en) | 2004-01-31 | 2006-08-29 | Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and use thereof as medicaments |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1713804B1 (en) |
JP (1) | JP4838730B2 (en) |
KR (1) | KR20060132672A (en) |
CN (1) | CN1910182A (en) |
AT (1) | ATE389654T1 (en) |
AU (1) | AU2005209368A1 (en) |
BR (1) | BRPI0507321A (en) |
CA (1) | CA2554527A1 (en) |
DE (2) | DE102004004971B3 (en) |
IL (1) | IL176915A0 (en) |
MA (1) | MA28340A1 (en) |
MX (1) | MXPA06007954A (en) |
NO (1) | NO20063859L (en) |
RU (1) | RU2006131307A (en) |
WO (1) | WO2005073231A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20110235A1 (en) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | PHARMACEUTICAL COMBINATIONS INCLUDING LINAGLIPTIN AND METMORPHINE |
PT2074123E (en) | 2006-10-16 | 2013-01-22 | Bionomics Ltd | Novel anxiolytic compounds |
US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
EP2582709B1 (en) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
CA2828780A1 (en) | 2011-03-02 | 2012-09-07 | Bionomics Limited | Novel small-molecules as therapeutics |
EP2683701B1 (en) | 2011-03-08 | 2014-12-24 | Sanofi | Oxathiazine derivatives substituted with benzyl or heteromethylene groups, method for their preparation, their usage as medicament, medicament containing same and its use |
US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
AU2012253237B2 (en) | 2011-05-12 | 2015-09-24 | Bionomics Limited | Methods for preparing naphthyridines |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2193252T3 (en) * | 1995-08-02 | 2003-11-01 | Darwin Discovery Ltd | QUINOLONAS AND ITS THERAPEUTIC USE. |
GB0205165D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
CN1652784A (en) * | 2002-05-14 | 2005-08-10 | 加利福尼亚大学董事会 | Substituted quinolone carboxylic acids, their derivatives, sites of action, and uses thereof |
-
2004
- 2004-01-31 DE DE102004004971A patent/DE102004004971B3/en not_active Expired - Fee Related
-
2005
- 2005-01-15 WO PCT/EP2005/000373 patent/WO2005073231A1/en active IP Right Grant
- 2005-01-15 CA CA002554527A patent/CA2554527A1/en not_active Abandoned
- 2005-01-15 EP EP05700960A patent/EP1713804B1/en not_active Expired - Lifetime
- 2005-01-15 MX MXPA06007954A patent/MXPA06007954A/en not_active Application Discontinuation
- 2005-01-15 BR BRPI0507321-9A patent/BRPI0507321A/en not_active Application Discontinuation
- 2005-01-15 JP JP2006549992A patent/JP4838730B2/en not_active Expired - Fee Related
- 2005-01-15 AT AT05700960T patent/ATE389654T1/en not_active IP Right Cessation
- 2005-01-15 RU RU2006131307/04A patent/RU2006131307A/en not_active Application Discontinuation
- 2005-01-15 KR KR1020067015358A patent/KR20060132672A/en not_active Application Discontinuation
- 2005-01-15 DE DE502005003310T patent/DE502005003310D1/en not_active Expired - Lifetime
- 2005-01-15 CN CNA2005800028932A patent/CN1910182A/en active Pending
- 2005-01-15 AU AU2005209368A patent/AU2005209368A1/en not_active Abandoned
-
2006
- 2006-07-17 IL IL176915A patent/IL176915A0/en unknown
- 2006-07-28 MA MA29219A patent/MA28340A1/en unknown
- 2006-08-29 NO NO20063859A patent/NO20063859L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0507321A (en) | 2007-06-26 |
CN1910182A (en) | 2007-02-07 |
JP4838730B2 (en) | 2011-12-14 |
AU2005209368A1 (en) | 2005-08-11 |
MXPA06007954A (en) | 2007-03-21 |
EP1713804B1 (en) | 2008-03-19 |
DE502005003310D1 (en) | 2008-04-30 |
JP2007519651A (en) | 2007-07-19 |
IL176915A0 (en) | 2006-12-10 |
WO2005073231A1 (en) | 2005-08-11 |
CA2554527A1 (en) | 2005-08-11 |
EP1713804A1 (en) | 2006-10-25 |
DE102004004971B3 (en) | 2005-09-15 |
KR20060132672A (en) | 2006-12-21 |
MA28340A1 (en) | 2006-12-01 |
RU2006131307A (en) | 2008-03-10 |
ATE389654T1 (en) | 2008-04-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20063859L (en) | Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and use thereof as medicaments | |
NO20063865L (en) | Heterocyclic substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | |
TNSN06409A1 (en) | Novel fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof | |
SE0301010D0 (en) | Novel compounds | |
SE0301009D0 (en) | Novel compounds | |
NO20070224L (en) | 2-urea-4-phenylthiazole derivatives, preparation and therapeutic use thereof | |
NO20085068L (en) | Phenylamino-benzoxazole-substituted carboxylic acids, process for their preparation and use thereof as medicaments | |
WO2006099943A8 (en) | Amide-substituted 8-n-benzimidazoles, method for the production thereof, and use of the same as medicaments | |
RS20050019A (en) | Heterocyclically substituted benzoylureas,method for their production and their use as medicaments | |
ATE433447T1 (en) | PYRIMIIDINE COMPOUNDS | |
NO20085067L (en) | 4,5-diphenyl-pyrimidinyl substituted carboxylic acids, processes for their preparation and use thereof as medicaments | |
NO20071577L (en) | Biphenyloxyacetic acid derivatives for the treatment of respiratory diseases | |
NO20064078L (en) | Substituted azetidine compositions, their preparation and use as drugs | |
RS20060015A (en) | Substituted thiazole- benzoisothiazole dioxide derivatives, method for the production thereof and use of the same | |
EA200801608A1 (en) | DERIVATIVES OF BENZIMIDAZOLONIC CARBONIC ACID | |
NO20080394L (en) | N- (arylalkyl) -1H-pyrrolopyridine-2-carboxamide derivatives, preparation and use thereof | |
NO20060718L (en) | Substituted thiophones and their use | |
DE502005008057D1 (en) | SUBSTITUTED CYCLOPENTE COMPOUNDS | |
TW200616985A (en) | Salicylthiazoles substituted by diphenylamine or diphenylamine derivatives, process for their preparation and their use | |
EA200600760A1 (en) | NEW COMPOUNDS PHENILPYRIDILPIPERAZINE, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
TNSN06233A1 (en) | 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments | |
NO20063790L (en) | Substituted azetidine compositions as cyclooxygenase-1-cyclooxygenase-2 inhibitors, and their preparation and use as medicaments | |
NO20054418L (en) | Substituted benzoylureidopyridylpiperidine and pyrrolidinecarboxylic acid derivatives, their preparation and use | |
TW200505892A (en) | Substituted 3-(benzoylureido)thiophene derivatives, processes for preparing them and their use | |
MX2007010841A (en) | Substituted, bicyclic 8-pyrrolidino-benzimidazoles, method for their production and their use as medicaments. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |