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NO20044590L - Fremgansmate og anordning for optisk deteksjon og analyse av partikler - Google Patents

Fremgansmate og anordning for optisk deteksjon og analyse av partikler

Info

Publication number
NO20044590L
NO20044590L NO20044590A NO20044590A NO20044590L NO 20044590 L NO20044590 L NO 20044590L NO 20044590 A NO20044590 A NO 20044590A NO 20044590 A NO20044590 A NO 20044590A NO 20044590 L NO20044590 L NO 20044590L
Authority
NO
Norway
Prior art keywords
optical element
metal
optical
particles
close
Prior art date
Application number
NO20044590A
Other languages
English (en)
Inventor
Robert Jeffry Geddes Carr
Original Assignee
Nanosight Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanosight Ltd filed Critical Nanosight Ltd
Publication of NO20044590L publication Critical patent/NO20044590L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SAMMENDRAG Det er beskrevet en fremgangsmåte og et apparat for enkeltvis deteksjon av partikler eller submikron-strukturer slik som biologiske molekyler og virus ved å benytte et optisk element (100) som omfatter et optisk transparent substrat (1) delvis belagt med en tynn film av metall (2) belyst med en optisk stråle (4) som treffer et område (3) av overflaten til det optiske metallet som ikke er belagt med metall ved et punkt tilstøtende eller nær det metallbelagte område til det optiske elementet, slik at strålen forplanter seg over, men nær og hovedsakelig parallelt med metalloverflaten som definerer en målesone hvorfra submikron-partikler (7) som befinner seg i en prøve (6) plassert i kontakt med det optiske elementet, sprer eller sender ut lys som kan detekteres i fjernfeltet ved hjelp av konvensjonelle foto-detektorsystemer. Apparatet kan være utformet i en strømningscelle- eller optisk mikroskop-konfigurasjon.
NO20044590A 2002-04-29 2004-10-25 Fremgansmate og anordning for optisk deteksjon og analyse av partikler NO20044590L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0209666A GB2388189B (en) 2002-04-29 2002-04-29 Optical detection and analysis of particles
PCT/GB2003/001827 WO2003093801A1 (en) 2002-04-29 2003-04-29 Optical detection and analysis of particles

Publications (1)

Publication Number Publication Date
NO20044590L true NO20044590L (no) 2005-01-28

Family

ID=9935629

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044590A NO20044590L (no) 2002-04-29 2004-10-25 Fremgansmate og anordning for optisk deteksjon og analyse av partikler

Country Status (13)

Country Link
US (2) US7399600B2 (no)
EP (1) EP1499871B1 (no)
JP (1) JP4002577B2 (no)
AT (1) ATE497154T1 (no)
AU (1) AU2003224315B2 (no)
CA (1) CA2482979C (no)
DE (1) DE60335872D1 (no)
DK (1) DK1499871T3 (no)
ES (1) ES2360906T3 (no)
GB (1) GB2388189B (no)
NO (1) NO20044590L (no)
WO (1) WO2003093801A1 (no)
ZA (1) ZA200408658B (no)

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US10031061B2 (en) 2009-05-13 2018-07-24 Intellicyt Corporation Flow measurement and control for improved quantification of particles in flow cytometry
CN102549445B (zh) 2009-09-28 2015-04-08 皇家飞利浦电子股份有限公司 用于单个颗粒检测的生物传感器系统
DE102009045075A1 (de) 2009-09-28 2011-04-07 Carl Zeiss Ag Messung des Dispergierungszustandes von nanoskaligen Füllstoffen in flüssigen und viskosen Medien
CA2791905A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarkers for theranostics
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US8681215B2 (en) 2011-04-29 2014-03-25 ProteinSimple Method and particle analyzer for determining a broad particle size distribution
GB2493391B (en) 2011-08-05 2015-09-16 Malvern Instr Ltd Optical detection and analysis of particles
US20130330711A1 (en) * 2012-06-06 2013-12-12 National Taiwan University Sensor for detection of a target of interest
US9958448B2 (en) 2012-10-23 2018-05-01 Caris Life Sciences Switzerland Holdings Gmbh Aptamers and uses thereof
US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
US9939443B2 (en) 2012-12-19 2018-04-10 Caris Life Sciences Switzerland Holdings Gmbh Compositions and methods for aptamer screening
US9194848B2 (en) 2013-03-15 2015-11-24 Practichem, Llc Multi-measurement flow cell assembly for liquid chromatography
EP2972154A4 (en) * 2013-03-15 2016-11-16 Practichem Llc MULTI-MEASUREMENT CIRCULATION TANK KIT FOR LIQUID PHASE CHROMATOGRAPHY
WO2015031694A2 (en) 2013-08-28 2015-03-05 Caris Science, Inc. Oligonucleotide probes and uses thereof
CN104518835B (zh) * 2013-10-08 2019-07-23 中兴通讯股份有限公司 一种可见光通信mimo系统的接收装置
GB2520491A (en) * 2013-11-20 2015-05-27 Malvern Instr Ltd Improvements in or relating to calibration of instruments
US9964487B2 (en) * 2013-12-23 2018-05-08 Koninklijke Philips N.V. Detection apparatus for detecting particles
KR101765070B1 (ko) 2015-02-25 2017-08-04 연세대학교 원주산학협력단 세포의 움직임 분석을 통한 세포 구별 방법 및 기구
CA2979361A1 (en) 2015-03-09 2016-09-15 Caris Science, Inc. Method of preparing oligonucleotide libraries
IL318703A (en) 2015-06-29 2025-03-01 Caris Science Inc Therapeutic oligonucleotides
EP3328873A4 (en) 2015-07-28 2019-04-10 Caris Science, Inc. TARGETED OLIGONUCLEOTIDES
US11857575B2 (en) 2015-11-02 2024-01-02 Takeda Pharmaceutical Company Limited Mesenchymal stem cell-derived exosomes and their uses
US20170121685A1 (en) 2015-11-02 2017-05-04 Tigenix S.A.U. Mesenchymal stem cell-derived exosomes and their uses
WO2017093466A1 (en) 2015-12-02 2017-06-08 Gothenburg Sensor Devices Ab A method for determining a hydrodynamic size of an object
JP2019516393A (ja) 2016-03-18 2019-06-20 カリス サイエンス インコーポレイテッド オリゴヌクレオチドプローブおよびその使用
WO2017205686A1 (en) 2016-05-25 2017-11-30 Caris Science, Inc. Oligonucleotide probes and uses thereof
RU174054U1 (ru) * 2016-10-24 2017-09-27 Общество с ограниченной ответственностью Фотокор Инвертированный анализатор траекторий наночастиц
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CN108051362B (zh) * 2017-11-09 2021-10-08 中国科学院微电子研究所 一种针对单个纳米颗粒的检测方法
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EP3830547B1 (en) 2018-08-01 2023-11-29 Sartorius BioAnalytical Instruments, Inc. Methods, kits and stain compositions for flow cytometry evaluation of unassociated virus-size particles using multiple fluorogenic dyes
JP7462632B2 (ja) 2018-11-30 2024-04-05 カリス エムピーアイ インコーポレイテッド 次世代分子プロファイリング
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RU204569U1 (ru) * 2021-03-23 2021-05-31 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский университет "Московский институт электронной техники" Анализатор траекторий наночастиц в объеме жидкости
CN118984933A (zh) 2022-02-07 2024-11-19 马尔文帕纳科公司 颗粒分析

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GB2326229A (en) * 1997-06-13 1998-12-16 Robert Jeffrey Geddes Carr Detecting and analysing submicron particles
CA2403427C (en) * 2000-03-22 2013-04-30 M. Cynthia Goh Method and apparatus for assay for multiple analytes
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US6804007B2 (en) * 2002-09-10 2004-10-12 Reichert, Inc. Apparatus for multiplexing two surface plasma resonance channels onto a single linear scanned array

Also Published As

Publication number Publication date
GB2388189A (en) 2003-11-05
DK1499871T3 (da) 2011-05-16
GB2388189B (en) 2006-01-11
US20080252884A1 (en) 2008-10-16
WO2003093801A1 (en) 2003-11-13
CA2482979C (en) 2013-04-02
EP1499871B1 (en) 2011-01-26
US7751053B2 (en) 2010-07-06
ES2360906T3 (es) 2011-06-10
DE60335872D1 (de) 2011-03-10
ZA200408658B (en) 2006-04-26
EP1499871A1 (en) 2005-01-26
ATE497154T1 (de) 2011-02-15
AU2003224315B2 (en) 2008-06-12
CA2482979A1 (en) 2003-11-13
JP4002577B2 (ja) 2007-11-07
AU2003224315A1 (en) 2003-11-17
GB0209666D0 (en) 2002-06-05
US20050226129A1 (en) 2005-10-13
JP2005524083A (ja) 2005-08-11
US7399600B2 (en) 2008-07-15

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