[go: up one dir, main page]

NO20025811D0 - Forbindelser som er effektive som beta-2-adrenoreseptor- anonister så vel som PDE4-inhibitorer - Google Patents

Forbindelser som er effektive som beta-2-adrenoreseptor- anonister så vel som PDE4-inhibitorer

Info

Publication number
NO20025811D0
NO20025811D0 NO20025811A NO20025811A NO20025811D0 NO 20025811 D0 NO20025811 D0 NO 20025811D0 NO 20025811 A NO20025811 A NO 20025811A NO 20025811 A NO20025811 A NO 20025811A NO 20025811 D0 NO20025811 D0 NO 20025811D0
Authority
NO
Norway
Prior art keywords
anonists
adrenoreceptor
beta
compounds
effective
Prior art date
Application number
NO20025811A
Other languages
English (en)
Other versions
NO20025811L (no
Inventor
Armin Hatzelmann
Daniela Bundschuh
Manfrid Eltze
Geert Jan Sterk
Yvonne Johanna Van Der Laan
Hendrik Timmermann
Johannes A M Christiaans
Paulus Johannes Gaurer Brundel
Original Assignee
Altana Pharma Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Bv filed Critical Altana Pharma Bv
Publication of NO20025811D0 publication Critical patent/NO20025811D0/no
Publication of NO20025811L publication Critical patent/NO20025811L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/32Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20025811A 2000-06-05 2002-12-03 Forbindelser som er effektive som beta-2-adrenoreseptor- agonister så vel som PDE4-inhibitorer NO20025811L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00111795 2000-06-05
PCT/EP2001/006230 WO2001094319A1 (en) 2000-06-05 2001-06-01 Compounds effective as beta-2-adrenoreceptor agonists as well as pde4-inhibitors

Publications (2)

Publication Number Publication Date
NO20025811D0 true NO20025811D0 (no) 2002-12-03
NO20025811L NO20025811L (no) 2003-02-04

Family

ID=8168897

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025811A NO20025811L (no) 2000-06-05 2002-12-03 Forbindelser som er effektive som beta-2-adrenoreseptor- agonister så vel som PDE4-inhibitorer

Country Status (20)

Country Link
US (1) US6933296B2 (no)
EP (1) EP1296956A1 (no)
JP (1) JP2003535850A (no)
KR (1) KR20030031907A (no)
CN (1) CN1471515A (no)
AU (2) AU6233201A (no)
BR (1) BR0111440A (no)
CA (1) CA2411351A1 (no)
CZ (1) CZ20023997A3 (no)
EA (1) EA005824B1 (no)
HK (1) HK1052346A1 (no)
HU (1) HUP0301240A3 (no)
IL (1) IL152846A0 (no)
MX (1) MXPA02012042A (no)
NO (1) NO20025811L (no)
NZ (1) NZ522882A (no)
PL (1) PL358057A1 (no)
SK (1) SK17052002A3 (no)
WO (1) WO2001094319A1 (no)
ZA (1) ZA200209598B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064584A1 (en) 2001-02-15 2002-08-22 Altana Pharma Ag Phthalayinone-piperidino-derivatives as pde4 inhibitors
CN1503792A (zh) 2001-04-25 2004-06-09 ��̹��ҽҩ��˾ 新的酞嗪酮
US7022696B2 (en) 2001-04-25 2006-04-04 Altana Pharma Ag Piperazino-derivatives and their use as PDE4 inhibitor
ES2195785B1 (es) 2002-05-16 2005-03-16 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
CA2494643A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-n-oxide-derivatives
WO2004018451A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Pyridazinone-derivatives as pde4 inhibitors
DE60313472T2 (de) * 2002-08-10 2008-01-24 Nycomed Gmbh Pyrrolidindion-substituierte piperidin-phthalazone als pde4-inhibitoren
CA2511496A1 (en) * 2002-12-23 2004-07-15 Artesian Therapeutics, Inc. Cardiotonic compounds with inhibitory activity against .beta.-adrenergic receptors and phosphodiesterase
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
ES2232306B1 (es) 2003-11-10 2006-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
EP1716123A1 (en) * 2004-02-04 2006-11-02 Altana Pharma AG Pyridazinone derivatives and their use as pde4 inhibitors
CA2554797C (en) * 2004-02-04 2012-09-04 Altana Pharma Ag 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
ES2251866B1 (es) 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
US20070225217A1 (en) 2005-11-09 2007-09-27 Combinatorx, Incorporated Methods, compositions, and kits for the treatment of medical conditions
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
GB0805535D0 (en) 2008-03-27 2008-04-30 Univ Leicester Scar prevention
JP5529131B2 (ja) * 2008-08-13 2014-06-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング キマーゼ阻害薬
AU2011253203A1 (en) * 2010-05-10 2012-11-22 Gilead Sciences, Inc. Bifunctional quinoline derivatives
UY33373A (es) 2010-05-10 2011-12-30 Gilead Sciences Inc ?Compuestos de pirazolopiridina bifuncionales, su uso en terapia y composiciones que los comprenden?.
WO2012171900A1 (en) * 2011-06-17 2012-12-20 Nycomed Gmbh Novel phthalazinone-pyrrolopyrimidinecarboxamide derivatives
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
GB2513297A (en) 2013-03-08 2014-10-29 Univ Leicester Methods
EP3877376B1 (en) 2018-11-06 2023-08-23 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
AU2019374812B2 (en) 2018-11-06 2025-03-06 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
JP2023526247A (ja) * 2020-05-13 2023-06-21 エッジワイズ セラピューティクス, インコーポレイテッド 神経筋疾患の処置のためのピリダジノン化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030835B1 (en) * 1979-12-05 1983-05-11 Morishita Pharmaceutical Co. Ltd. Derivatives of 2-substituted-6-phenyl-3(2h)pyridazinone, their production and pharmaceutical compositions containing them
JPS58146571A (ja) * 1982-02-25 1983-09-01 Morishita Seiyaku Kk ウレア誘導体およびその製造法
PL164079B1 (pl) * 1990-06-15 1994-06-30 Akad Medyczna posób wytwarzania nowych 2-amlnoalkilopochodnych 5-aminometyleno-6-/p-chlorofenylo /-4,5-dihydro-2H- plrydazyn -3-onu
CA2400368A1 (en) 1992-12-02 1994-06-09 Allen J. Duplantier Catechol diethers as selective pde iv inhibitors
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
DE69811645T2 (de) * 1997-01-15 2003-12-04 Altana Pharma Ag Phtalazinonen
WO1998037894A1 (de) 1997-02-28 1998-09-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse-agonisten
IL136359A (en) 1997-12-15 2003-03-12 Byk Gulden Lomberg Chem Fab Dihydrobenzofuran substituted phthalazin-1-one derivatives and pharmaceutical compositions containing the same
WO1999031071A1 (en) 1997-12-15 1999-06-24 Byk Gulden Lomberg Chemische Fabrik Gmbh New phthalazinones
EP0934933A1 (en) 1998-02-06 1999-08-11 Byk Gulden Lomberg Chemische Fabrik GmbH Phthalazinones
DZ2876A1 (fr) 1998-08-26 2003-12-15 Smithkline Beecham Corp Composition comprenant un inhibiteur de pde4 et unbroncho-dilatateur beta-andrenergique, et procédé pour leur préparation.

Also Published As

Publication number Publication date
CZ20023997A3 (cs) 2003-05-14
IL152846A0 (en) 2003-06-24
BR0111440A (pt) 2003-06-03
US20030195215A1 (en) 2003-10-16
HUP0301240A3 (en) 2004-03-29
EA005824B1 (ru) 2005-06-30
KR20030031907A (ko) 2003-04-23
CN1471515A (zh) 2004-01-28
US6933296B2 (en) 2005-08-23
HUP0301240A2 (hu) 2003-12-29
ZA200209598B (en) 2003-07-29
CA2411351A1 (en) 2001-12-13
NZ522882A (en) 2004-07-30
PL358057A1 (en) 2004-08-09
MXPA02012042A (es) 2004-08-19
EP1296956A1 (en) 2003-04-02
SK17052002A3 (sk) 2003-12-02
AU6233201A (en) 2001-12-17
EA200201252A1 (ru) 2003-06-26
NO20025811L (no) 2003-02-04
HK1052346A1 (zh) 2003-09-11
WO2001094319A1 (en) 2001-12-13
AU2001262332B2 (en) 2006-05-25
JP2003535850A (ja) 2003-12-02

Similar Documents

Publication Publication Date Title
NO20025811D0 (no) Forbindelser som er effektive som beta-2-adrenoreseptor- anonister så vel som PDE4-inhibitorer
NO20030867D0 (no) Hydroksamderivater anvendelig som deacetylaseinhibitorer
NO20030055D0 (no) Colchinolderivater som angiogenese inhibitorer
NO20021239L (no) Pteridinoner som kinase-inhibitorer
NO20023828L (no) Pyrimidin-4-on derivater som LDL-PLA2 inhibitorer
NO20014642L (no) Aminopyrimidiner som sorbitol-dehydrogenase-inhibitorer
NO20024997D0 (no) 2-guanidino-4-arylkinazoliner som NHE-3-inhibitorer
PT1370553E (pt) Inibidores de rhoquinase
NO20026196L (no) Kinazolinditosylatsalt-forbindelser
DE60234125D1 (de) E inhibitoren
NO20040686L (no) Forbindelser som pavirker glukokinase
DE60218138D1 (de) Rho-kinase inhibitoren
ATE333454T1 (de) Metalloproteinaseinhibitoren
DK1619192T3 (da) Arylkondeserede azapolycykliske forbindelser
NO20015065L (no) Pyrazolobenzodiazepiner som CDK2-inhibitorer
NO20030135D0 (no) Piperidinforbindelser for bruk som CCR-3 inhibitorer
NO20033618D0 (no) Ftalayinon-piperidino-derivater som PDE-4-inhibitorer
DK1272488T3 (da) Tri-aryl-substitueret ethan-PDE4-inhibitorer
NO20021959L (no) Tetrahydrotiopyranftalazinon-derivater som PDE4-inhibitorer
DK1263734T3 (da) 3-thiomethylpyrazoler som pesticider
AR028220A1 (es) Novedosos compuestos
DK1217002T3 (da) 2-(4-pyridinyl)benzofuraner som metalloproteaseinhibitorer
NO20032255L (no) Dehalogen-forbindelser
NO20030303L (no) Kalsilytiske forbindelser
NO20031837D0 (no) Kalsilytiske forbindelser

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application