NO20020665D0 - Streptomyces Avermitilis gen som bestemmer forholdet til B2:B1 avermectiner - Google Patents

Streptomyces Avermitilis gen som bestemmer forholdet til B2:B1 avermectiner

Info

Publication number: NO20020665D0
Authority: NO; Norway
Prior art keywords: avermectins; determines; ratio; streptomyces avermitilis; avermitilis gene
Prior art date: 1999-08-12

Application number

NO20020665A

Other languages

English (en)

Norwegian (no)

Other versions

NO20020665L (no

Inventor

Kim Jonelle Stutzman-Engwall

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-12

Filing date

2002-02-11

Publication date

2002-02-11

2002-02-11 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2002-02-11 Publication of NO20020665L publication Critical patent/NO20020665L/no

2002-02-11 Publication of NO20020665D0 publication Critical patent/NO20020665D0/no

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO20020665A 1999-08-12 2002-02-11 Streptomyces Avermitilis gen som bestemmer forholdet til B2:B1 avermectiner NO20020665D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/372,934 US6248579B1 (en)	1998-02-13	1999-08-12	Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
PCT/IB2000/000996 WO2001012822A1 (en)	1999-08-12	2000-07-19	Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

Publications (2)

Publication Number	Publication Date
NO20020665L NO20020665L (no)	2002-02-11
NO20020665D0 true NO20020665D0 (no)	2002-02-11

Family

ID=23470234

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20020665A NO20020665D0 (no)	1999-08-12	2002-02-11	Streptomyces Avermitilis gen som bestemmer forholdet til B2:B1 avermectiner

Country Status (37)

Country	Link
US (8)	US6248579B1 (pt)
EP (1)	EP1200605B1 (pt)
JP (2)	JP3688640B2 (pt)
KR (1)	KR100486006B1 (pt)
CN (1)	CN1186447C (pt)
AP (2)	AP2002002419A0 (pt)
AR (1)	AR021450A1 (pt)
AT (1)	ATE283363T1 (pt)
AU (1)	AU779756B2 (pt)
BG (1)	BG106478A (pt)
BR (1)	BR0013093A (pt)
CA (1)	CA2381427A1 (pt)
CO (1)	CO5290296A1 (pt)
CZ (1)	CZ2002297A3 (pt)
DE (1)	DE60016231T2 (pt)
EA (1)	EA004569B1 (pt)
ES (1)	ES2231214T3 (pt)
GT (2)	GT200000138A (pt)
HK (1)	HK1046536B (pt)
HR (1)	HRP20020131A2 (pt)
HU (1)	HUP0202517A2 (pt)
IL (1)	IL147562A0 (pt)
IS (1)	IS6249A (pt)
MA (1)	MA26811A1 (pt)
MX (1)	MXPA02001514A (pt)
NO (1)	NO20020665D0 (pt)
OA (1)	OA11997A (pt)
PA (1)	PA8499201A1 (pt)
PE (1)	PE20010697A1 (pt)
PL (1)	PL353770A1 (pt)
PT (1)	PT1200605E (pt)
SK (1)	SK1382002A3 (pt)
TN (1)	TNSN00170A1 (pt)
UY (1)	UY26287A1 (pt)
WO (1)	WO2001012822A1 (pt)
YU (1)	YU8402A (pt)
ZA (1)	ZA200201071B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001012821A1 (en) *	1999-08-12	2001-02-22	Pfizer Products Inc.	Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
EP1474396B9 (en)	2002-02-05	2008-07-09	Bristol-Myers Squibb Company	N-substituted3-hydroxy-4-pyridinones and pharmaceuticals containing thereof
JP2005517406A (ja)	2002-02-12	2005-06-16	ファイザー・プロダクツ・インク	Ｂ２：Ｂ１アベルメクチン比を支配するＳｔｒｅｐｔｏｍｙｃｅｓａｖｅｒｍｉｔｉｌｉｓ遺伝子
US7943160B2 (en) *	2002-05-09	2011-05-17	Scimetrics Limited Corp.	Pest control methods
WO2004067549A2 (de) *	2003-01-31	2004-08-12	Max-Delbrück-Centrum für Molekulare Medizin	Peptide gegen kälteunverträglichkeit hervorrufende autoantikörper und ihre verwendung
KR100759130B1 (ko)	2005-02-12	2007-09-19	휴메드 주식회사	항 인테그린 항체 코팅스텐트 및 그의 제조방법
CN106148216B (zh)	2015-03-27	2019-06-04	浙江海正药业股份有限公司	一种链霉菌及其生产米尔贝霉素a3的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5525506A (en)	1987-01-23	1996-06-11	Pfizer Inc.	Process for production of avermectins and cultures therefor
US5234831A (en)	1987-01-23	1993-08-10	Pfizer Inc	Cultures for production of B avermectins
US5238848A (en)	1987-01-23	1993-08-24	Pfizer Inc	Cultures for production of avermectins
US5240850A (en)	1987-10-23	1993-08-31	Pfizer Inc.	Cultures for production of avermectin aglycones
ES2054822T3 (es)	1987-10-23	1994-08-16	Pfizer	Procedimiento para la produccion de agliconas de avermectinas y sus cultivos.
US5252474A (en)	1989-03-31	1993-10-12	Merck & Co., Inc.	Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
ATE129286T1 (de)	1989-03-31	1995-11-15	Merck & Co Inc	Klonierung von streptomyces avermitilis genen zur biosynthese von avermectin und verfahren zu ihrer verwendung.
AU6657294A (en)	1993-07-30	1995-02-28	Pfizer Inc.	Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
CN1040113C (zh) *	1993-10-05	1998-10-07	美国辉瑞有限公司	抗寄生虫药物多哇麦汀(doramectin)的中间体及其制备方法
FI942725L (fi)	1993-12-16	1995-06-17	Pfizer	Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta
HUP0100784A3 (en) *	1998-02-13	2004-10-28	Pfizer Prod Inc	Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

1999
- 1999-08-12 US US09/372,934 patent/US6248579B1/en not_active Expired - Fee Related
2000
- 2000-07-19 CZ CZ2002297A patent/CZ2002297A3/cs unknown
- 2000-07-19 DE DE60016231T patent/DE60016231T2/de not_active Expired - Fee Related
- 2000-07-19 MX MXPA02001514A patent/MXPA02001514A/es active IP Right Grant
- 2000-07-19 AP APAP/P/2002/002419A patent/AP2002002419A0/en unknown
- 2000-07-19 PT PT00942331T patent/PT1200605E/pt unknown
- 2000-07-19 CN CNB008117632A patent/CN1186447C/zh not_active Expired - Fee Related
- 2000-07-19 HU HU0202517A patent/HUP0202517A2/hu unknown
- 2000-07-19 KR KR10-2002-7001946A patent/KR100486006B1/ko not_active IP Right Cessation
- 2000-07-19 ES ES00942331T patent/ES2231214T3/es not_active Expired - Lifetime
- 2000-07-19 CA CA002381427A patent/CA2381427A1/en not_active Abandoned
- 2000-07-19 OA OA1200200024A patent/OA11997A/en unknown
- 2000-07-19 EP EP00942331A patent/EP1200605B1/en not_active Expired - Lifetime
- 2000-07-19 AP APAP/P/2002/002417A patent/AP2002002417A0/en unknown
- 2000-07-19 EA EA200200057A patent/EA004569B1/ru not_active IP Right Cessation
- 2000-07-19 PL PL00353770A patent/PL353770A1/xx unknown
- 2000-07-19 WO PCT/IB2000/000996 patent/WO2001012822A1/en active IP Right Grant
- 2000-07-19 JP JP2001516909A patent/JP3688640B2/ja not_active Expired - Fee Related
- 2000-07-19 YU YU8402A patent/YU8402A/sh unknown
- 2000-07-19 AT AT00942331T patent/ATE283363T1/de not_active IP Right Cessation
- 2000-07-19 IL IL14756200A patent/IL147562A0/xx unknown
- 2000-07-19 BR BR0013093-1A patent/BR0013093A/pt not_active Application Discontinuation
- 2000-07-19 AU AU57021/00A patent/AU779756B2/en not_active Ceased
- 2000-07-19 SK SK138-2002A patent/SK1382002A3/sk unknown
- 2000-08-04 CO CO00058850A patent/CO5290296A1/es not_active Application Discontinuation
- 2000-08-04 PA PA20008499201A patent/PA8499201A1/es unknown
- 2000-08-10 PE PE2000000813A patent/PE20010697A1/es not_active Application Discontinuation
- 2000-08-10 AR ARP000104129A patent/AR021450A1/es unknown
- 2000-08-10 UY UY26287A patent/UY26287A1/es not_active Application Discontinuation
- 2000-08-11 TN TNTNSN00170A patent/TNSN00170A1/fr unknown
- 2000-08-11 GT GT200000138A patent/GT200000138A/es unknown
- 2000-08-11 GT GT200000138CM patent/GT200000138CA/es unknown
2001
- 2001-01-22 US US09/766,898 patent/US6511841B2/en not_active Expired - Fee Related
- 2001-01-22 US US09/766,916 patent/US6509159B2/en not_active Expired - Fee Related
2002
- 2002-01-25 IS IS6249A patent/IS6249A/is unknown
- 2002-02-07 MA MA26511A patent/MA26811A1/fr unknown
- 2002-02-07 ZA ZA200201071A patent/ZA200201071B/en unknown
- 2002-02-11 NO NO20020665A patent/NO20020665D0/no not_active Application Discontinuation
- 2002-02-12 HR HR20020131A patent/HRP20020131A2/hr not_active Application Discontinuation
- 2002-03-05 BG BG106478A patent/BG106478A/bg unknown
- 2002-10-30 HK HK02107834.3A patent/HK1046536B/zh not_active IP Right Cessation
- 2002-11-27 US US10/306,249 patent/US6833263B2/en not_active Expired - Fee Related
- 2002-11-27 US US10/306,013 patent/US20030134313A1/en not_active Abandoned
- 2002-11-27 US US10/306,247 patent/US7029887B2/en not_active Expired - Fee Related
- 2002-11-27 US US10/306,246 patent/US20030129635A1/en not_active Abandoned
2004
- 2004-12-14 US US11/011,960 patent/US7259241B2/en not_active Expired - Fee Related
2005
- 2005-02-16 JP JP2005039041A patent/JP2005198658A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
JP2003507018A (ja)	2003-02-25
EP1200605A1 (en)	2002-05-02
CZ2002297A3 (cs)	2002-08-14
PL353770A1 (en)	2003-12-01
IL147562A0 (en)	2002-08-14
TNSN00170A1 (fr)	2005-11-10
JP3688640B2 (ja)	2005-08-31
US6511841B2 (en)	2003-01-28
HRP20020131A2 (en)	2003-12-31
BR0013093A (pt)	2002-08-13
PT1200605E (pt)	2005-04-29
AU779756B2 (en)	2005-02-10
DE60016231T2 (de)	2005-12-08
HUP0202517A2 (hu)	2002-11-28
SK1382002A3 (en)	2002-11-06
EA004569B1 (ru)	2004-06-24
US20050196777A1 (en)	2005-09-08
BG106478A (bg)	2004-02-27
KR100486006B1 (ko)	2005-05-03
ATE283363T1 (de)	2004-12-15
CN1370239A (zh)	2002-09-18
AP2002002419A0 (en)	2002-03-31
US6833263B2 (en)	2004-12-21
YU8402A (sh)	2006-03-03
CN1186447C (zh)	2005-01-26
US20030134313A1 (en)	2003-07-17
WO2001012822A1 (en)	2001-02-22
NO20020665L (no)	2002-02-11
AU5702100A (en)	2001-03-13
ZA200201071B (en)	2003-06-25
UY26287A1 (es)	2001-03-16
PE20010697A1 (es)	2001-07-05
KR20020022809A (ko)	2002-03-27
HK1046536A1 (en)	2003-01-17
GT200000138CA (es)	2002-02-02
DE60016231D1 (de)	2004-12-30
US7029887B2 (en)	2006-04-18
US20030129636A1 (en)	2003-07-10
AR021450A1 (es)	2002-07-17
US20030124607A1 (en)	2003-07-03
EP1200605B1 (en)	2004-11-24
EA200200057A1 (ru)	2002-06-27
MXPA02001514A (es)	2002-07-02
US7259241B2 (en)	2007-08-21
HK1046536B (zh)	2005-05-13
IS6249A (is)	2002-01-25
PA8499201A1 (es)	2001-12-14
US6248579B1 (en)	2001-06-19
US20030129635A1 (en)	2003-07-10
MA26811A1 (fr)	2004-12-20
AP2002002417A0 (en)	2002-03-31
CA2381427A1 (en)	2001-02-22
ES2231214T3 (es)	2005-05-16
US6509159B2 (en)	2003-01-21
US20010024818A1 (en)	2001-09-27
GT200000138A (es)	2002-02-02
OA11997A (en)	2006-04-18
CO5290296A1 (es)	2003-06-27
US20010016350A1 (en)	2001-08-23
JP2005198658A (ja)	2005-07-28

Publication	Publication Date	Title
AU5515901A (en)	2001-07-09	Gamma-phosphoester nucleoside triphosphates
AU2002363246A1 (en)	2003-05-12	Game with multiple chambers
NO20042112L (no)	2004-07-09	Anvendelse av glycosider av mono- og diacylglycerol som anti-inflammatoriske midler.
AU2001278694A1 (en)	2002-02-18	Avermectin derivatives
NO20020665D0 (no)	2002-02-11	Streptomyces Avermitilis gen som bestemmer forholdet til B2:B1 avermectiner
HK1168383A1 (en)	2012-12-28	Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
NO20004044L (no)	2000-10-11	Streptomyces Avertimilis gen som styrer forholdet av B2:B1 avermectiner
NO20020664D0 (no)	2002-02-11	Streptomyces Avermitilis gen som bestemmer forholdet B2:B1 avermectiner
EP1206477A4 (en)	2004-11-24	CLONING OF THE STREPTOMYCES AVERMITILIS GENES FOR THE GLYCOSYLATION OF AVERMECTIN AGLYCONES
DK1200605T3 (da)	2005-03-21	Streptomyces avermitilis gen, der dirigerer forholdet imellem B2:B1 avermectiner
AU2690500A (en)	2000-09-14	Avermectin aglycon synthase genes
AU2002230657A1 (en)	2002-06-11	Haplotypes of the sah gene
AU2002258684A1 (en)	2002-10-21	Assay methods for o-g1cnac transferase activity
AU2002359534A1 (en)	2003-06-10	Nucleoside analog libraries
AU2001268231A1 (en)	2001-12-17	Haplotypes of the pfkfb2 gene
AU2002226394A1 (en)	2002-07-16	Nucleoside diphosphate hydrolase
AU2002346601A1 (en)	2003-06-17	Novel 11-o-substituted ketolide derivatives

Legal Events

Date	Code	Title	Description
2004-06-21	FC2A	Withdrawal, rejection or dismissal of laid open patent application