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NO20010533D0 - Amid-derivater som er egnet som cytokininhibitorer - Google Patents

Amid-derivater som er egnet som cytokininhibitorer

Info

Publication number
NO20010533D0
NO20010533D0 NO20010533A NO20010533A NO20010533D0 NO 20010533 D0 NO20010533 D0 NO 20010533D0 NO 20010533 A NO20010533 A NO 20010533A NO 20010533 A NO20010533 A NO 20010533A NO 20010533 D0 NO20010533 D0 NO 20010533D0
Authority
NO
Norway
Prior art keywords
alkoxy
alkyl
halogeno
heterocyclyl
heteroaryl
Prior art date
Application number
NO20010533A
Other languages
English (en)
Other versions
NO20010533L (no
NO321017B1 (no
Inventor
Dearg Sutherland Brown
George Robert Brown
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO20010533D0 publication Critical patent/NO20010533D0/no
Publication of NO20010533L publication Critical patent/NO20010533L/no
Publication of NO321017B1 publication Critical patent/NO321017B1/no

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20010533A 1998-08-04 2001-01-31 Amid-derivater som er egnet som cytokininhibitorer, fremgangsmate for fremstilling derav, anvendelse derav og farmasoytisk preparat som omfatter amid-derivater. NO321017B1 (no)

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Application Number Priority Date Filing Date Title
GBGB9816837.0A GB9816837D0 (en) 1998-08-04 1998-08-04 Amide derivatives
PCT/GB1999/002494 WO2000007980A1 (en) 1998-08-04 1999-07-29 Amide derivatives which are useful as cytokine inhibitors

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NO20010533D0 true NO20010533D0 (no) 2001-01-31
NO20010533L NO20010533L (no) 2001-03-30
NO321017B1 NO321017B1 (no) 2006-02-27

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NO20010533A NO321017B1 (no) 1998-08-04 2001-01-31 Amid-derivater som er egnet som cytokininhibitorer, fremgangsmate for fremstilling derav, anvendelse derav og farmasoytisk preparat som omfatter amid-derivater.

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EP (1) EP1102743B1 (no)
JP (1) JP4502509B2 (no)
KR (1) KR100628285B1 (no)
CN (1) CN1243724C (no)
AT (1) ATE221047T1 (no)
AU (1) AU756292B2 (no)
BR (1) BRPI9912726B8 (no)
CA (1) CA2337770C (no)
CZ (1) CZ301971B6 (no)
DE (1) DE69902277T2 (no)
DK (1) DK1102743T3 (no)
ES (1) ES2178895T3 (no)
GB (1) GB9816837D0 (no)
HK (1) HK1037608A1 (no)
HU (1) HU230343B1 (no)
IL (2) IL141184A0 (no)
NO (1) NO321017B1 (no)
NZ (1) NZ509162A (no)
PL (1) PL195722B1 (no)
PT (1) PT1102743E (no)
RU (1) RU2220951C2 (no)
SK (1) SK286446B6 (no)
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HUP0103366A3 (en) 2002-12-28
JP2002522414A (ja) 2002-07-23
SK1722001A3 (en) 2001-08-06
CN1330631A (zh) 2002-01-09
CA2337770A1 (en) 2000-02-17
US6821965B1 (en) 2004-11-23
GB9816837D0 (en) 1998-09-30
PT1102743E (pt) 2002-12-31
IL141184A (en) 2009-11-18
IL141184A0 (en) 2002-02-10
RU2220951C2 (ru) 2004-01-10
ZA200100617B (en) 2002-01-22
BRPI9912726A (pt) 2001-05-02
BRPI9912726B8 (pt) 2021-07-06
PL195722B1 (pl) 2007-10-31
BRPI9912726B1 (pt) 2011-05-31
DE69902277D1 (de) 2002-08-29
CN1243724C (zh) 2006-03-01
KR100628285B1 (ko) 2006-09-27
ATE221047T1 (de) 2002-08-15
NO20010533L (no) 2001-03-30
AU756292B2 (en) 2003-01-09
CA2337770C (en) 2009-01-20
WO2000007980A1 (en) 2000-02-17
HK1037608A1 (en) 2002-02-15
EP1102743A1 (en) 2001-05-30
JP4502509B2 (ja) 2010-07-14
SK286446B6 (sk) 2008-10-07
HUP0103366A2 (hu) 2002-01-28
HU230343B1 (hu) 2016-02-29
ES2178895T3 (es) 2003-01-01
NZ509162A (en) 2004-01-30
CZ2001384A3 (cs) 2001-07-11
DK1102743T3 (da) 2002-09-30
EP1102743B1 (en) 2002-07-24
PL345809A1 (en) 2002-01-02
DE69902277T2 (de) 2003-06-18
AU5179199A (en) 2000-02-28
KR20010099608A (ko) 2001-11-09
CZ301971B6 (cs) 2010-08-18
NO321017B1 (no) 2006-02-27

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