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GB9623833D0 - Chemical compound - Google Patents

Chemical compound

Info

Publication number
GB9623833D0
GB9623833D0 GBGB9623833.2A GB9623833A GB9623833D0 GB 9623833 D0 GB9623833 D0 GB 9623833D0 GB 9623833 A GB9623833 A GB 9623833A GB 9623833 D0 GB9623833 D0 GB 9623833D0
Authority
GB
United Kingdom
Prior art keywords
chemical compound
chemical
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9623833.2A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Priority to GBGB9623833.2A priority Critical patent/GB9623833D0/en
Publication of GB9623833D0 publication Critical patent/GB9623833D0/en
Priority to CA002267782A priority patent/CA2267782A1/en
Priority to PCT/GB1997/003102 priority patent/WO1998022103A1/en
Priority to EP97912325A priority patent/EP0941084A1/en
Priority to AU49562/97A priority patent/AU4956297A/en
Priority to JP52331698A priority patent/JP2001504478A/en
Priority to ZA9710314A priority patent/ZA9710314B/en
Priority to NO992336A priority patent/NO992336L/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GBGB9623833.2A 1996-11-16 1996-11-16 Chemical compound Pending GB9623833D0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GBGB9623833.2A GB9623833D0 (en) 1996-11-16 1996-11-16 Chemical compound
CA002267782A CA2267782A1 (en) 1996-11-16 1997-11-12 Raf kinase inhibitors
PCT/GB1997/003102 WO1998022103A1 (en) 1996-11-16 1997-11-12 Raf kinase inhibitors
EP97912325A EP0941084A1 (en) 1996-11-16 1997-11-12 Raf kinase inhibitors
AU49562/97A AU4956297A (en) 1996-11-16 1997-11-12 Raf kinase inhibitors
JP52331698A JP2001504478A (en) 1996-11-16 1997-11-12 RAF kinase inhibitor
ZA9710314A ZA9710314B (en) 1996-11-16 1997-11-14 Chemical compounds.
NO992336A NO992336L (en) 1996-11-16 1999-05-14 Raf kinase inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9623833.2A GB9623833D0 (en) 1996-11-16 1996-11-16 Chemical compound

Publications (1)

Publication Number Publication Date
GB9623833D0 true GB9623833D0 (en) 1997-01-08

Family

ID=10803023

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9623833.2A Pending GB9623833D0 (en) 1996-11-16 1996-11-16 Chemical compound

Country Status (8)

Country Link
EP (1) EP0941084A1 (en)
JP (1) JP2001504478A (en)
AU (1) AU4956297A (en)
CA (1) CA2267782A1 (en)
GB (1) GB9623833D0 (en)
NO (1) NO992336L (en)
WO (1) WO1998022103A1 (en)
ZA (1) ZA9710314B (en)

Families Citing this family (65)

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Publication number Priority date Publication date Assignee Title
GB9816837D0 (en) 1998-08-04 1998-09-30 Zeneca Ltd Amide derivatives
US7772432B2 (en) 1991-09-19 2010-08-10 Astrazeneca Ab Amidobenzamide derivatives which are useful as cytokine inhibitors
AU739066B2 (en) 1997-09-23 2001-10-04 Astrazeneca Ab Amide derivatives for the treatment of diseases mediated by cytokines
US7517880B2 (en) 1997-12-22 2009-04-14 Bayer Pharmaceuticals Corporation Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
SK285371B6 (en) * 1997-12-22 2006-12-07 Bayer Corporation Aryl and heteroaryl substituted heterocyclic ureas, their use and pharmaceutical composition containing thereof
US7329670B1 (en) 1997-12-22 2008-02-12 Bayer Pharmaceuticals Corporation Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
NZ505844A (en) * 1997-12-22 2003-10-31 Bayer Ag Inhibition of raf kinase using substituted heterocyclic ureas
BR9910467A (en) 1998-05-15 2001-01-09 Astrazeneca Ab Amide-derived compound, process for preparing it, pharmaceutical composition, and use of an amide-derived compound
PT1077931E (en) 1998-05-15 2005-03-31 Astrazeneca Ab BEZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES
TR200100300T2 (en) 1998-08-04 2001-07-23 Astrazeneca Ab Amide derivatives useful as inhibitors in the production of cytokines
JP2002525358A (en) 1998-09-25 2002-08-13 アストラゼネカ アクチボラグ Benzamide derivatives and their use as cytokine inhibitors
EP1117653B1 (en) 1998-10-01 2003-02-05 AstraZeneca AB Quinoline and quinazoline derivatives and their use as inhibitors of cytokine mediated diseases
US6194399B1 (en) 1998-10-09 2001-02-27 Scriptgen Pharmaceuticals, Inc. Aryldiamine derivatives useful as antibacterial agents
ME00275B (en) 1999-01-13 2011-02-10 Bayer Corp ?-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
EP1140840B1 (en) 1999-01-13 2006-03-22 Bayer Pharmaceuticals Corp. -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
JP2002534468A (en) 1999-01-13 2002-10-15 バイエル コーポレイション ω-Carboxyaryl-substituted diphenylureas as p38 kinase inhibitors
TR200103336T2 (en) 1999-03-17 2002-04-22 Astrazeneca Ab Amide derivatives.
DE60022328T2 (en) 1999-03-17 2006-06-01 Astrazeneca Ab AMID DERIVATIVES
GB9906566D0 (en) 1999-03-23 1999-05-19 Zeneca Ltd Chemical compounds
GB9924092D0 (en) 1999-10-13 1999-12-15 Zeneca Ltd Pyrimidine derivatives
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7371763B2 (en) 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
AU2002353228B2 (en) 2001-12-21 2008-09-11 The Welcome Trust Genes
PT1580188E (en) 2002-02-11 2012-01-25 Bayer Healthcare Llc Aryl ureas as kinase inhibitors
PT1478358E (en) 2002-02-11 2013-09-11 Bayer Healthcare Llc Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis
US7279576B2 (en) 2002-12-31 2007-10-09 Deciphera Pharmaceuticals, Llc Anti-cancer medicaments
US7202257B2 (en) 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
US7144911B2 (en) 2002-12-31 2006-12-05 Deciphera Pharmaceuticals Llc Anti-inflammatory medicaments
WO2004064733A2 (en) * 2003-01-15 2004-08-05 Board Of Regents, University Of Texas System The use of c-raf inhibitors for the treatment of neurodegenerative diseases
DK1636585T3 (en) 2003-05-20 2008-05-26 Bayer Pharmaceuticals Corp Diarylurines with kinase inhibitory activity
JP5001650B2 (en) * 2003-07-11 2012-08-15 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Benzimidazole carboxamide
PT1663978E (en) 2003-07-23 2008-02-15 Bayer Pharmaceuticals Corp Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
GB0324790D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Amide derivatives
WO2006007520A1 (en) * 2004-07-01 2006-01-19 Wisconsin Alumni Research Foundation Hydroxybenazamide compounds for treatment of cancer
CA2577278A1 (en) * 2004-09-01 2006-03-09 Astrazeneca Ab Quinazolinone derivatives and their use as b-raf inhibitors
TW200635899A (en) * 2004-12-22 2006-10-16 Astrazeneca Ab Chemical compounds
US7652041B2 (en) 2005-01-14 2010-01-26 Millennium Pharmaceuticals, Inc. Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity
AU2006315467B2 (en) * 2005-11-14 2013-02-07 Curis, Inc. Bisamide inhibitors of hedgehog signaling
EP2146716A4 (en) 2007-04-20 2010-08-11 Deciphera Pharmaceuticals Llc Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
AU2011263436A1 (en) * 2010-05-11 2012-08-23 Mahesh Kandula 4, 6 -dibenzoylamino- 2 -methyl- pyrimidine derivatives and their use for the treatment of cancer
US9198911B2 (en) 2010-11-02 2015-12-01 The Trustees Of Columbia University In The City Of New York Methods for treating hair loss disorders
WO2013032975A1 (en) 2011-08-29 2013-03-07 Ticona Llc Thermotropic liquid crystalline polymer with improved low shear viscosity
WO2013032981A1 (en) 2011-08-29 2013-03-07 Ticona Llc High flow liquid crystalline polymer composition
US8778221B2 (en) 2011-08-29 2014-07-15 Ticona Llc Aromatic amide compound
WO2013032967A1 (en) 2011-08-29 2013-03-07 Ticona Llc Cast molded parts formed form a liquid crystalline polymer
TW201319118A (en) 2011-08-29 2013-05-16 Ticona Llc Melt polymerization of low melt viscosity liquid crystalline polymers
KR20140059825A (en) 2011-08-29 2014-05-16 티코나 엘엘씨 High flow liquid crystalline polymer composition
WO2013032971A1 (en) 2011-08-29 2013-03-07 Ticona Llc Melt-extruded substrate for use in thermoformed articles
US8906258B2 (en) 2011-08-29 2014-12-09 Ticona Llc Heat-resistant liquid crystalline polymer composition having a low melting temperature
PT2830662T (en) 2012-03-29 2018-11-29 Univ Columbia Methods for treating hair loss disorders
US8461179B1 (en) 2012-06-07 2013-06-11 Deciphera Pharmaceuticals, Llc Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
WO2014130275A2 (en) 2013-02-22 2014-08-28 Ticona Llc High performance polymer composition with improved flow properties
WO2015041534A1 (en) 2013-09-20 2015-03-26 Stichting Het Nederlands Kanker Instituut P90rsk in combination with raf/erk/mek
WO2015041533A1 (en) 2013-09-20 2015-03-26 Stichting Het Nederlands Kanker Instituut Rock in combination with mapk-pathway
WO2015156674A2 (en) 2014-04-10 2015-10-15 Stichting Het Nederlands Kanker Instituut Method for treating cancer
WO2015178770A1 (en) 2014-05-19 2015-11-26 Stichting Het Nederlands Kanker Instituut Compositions for cancer treatment
SG11202007198WA (en) 2018-01-31 2020-08-28 Deciphera Pharmaceuticals Llc Combination therapy for the treatment of gastrointestinal stromal tumors
CA3089630A1 (en) 2018-01-31 2019-08-08 Deciphera Pharmaceuticals, Llc Combination therapy for the treatment of mastocytosis
WO2020185812A1 (en) 2019-03-11 2020-09-17 Teva Pharmaceuticals International Gmbh Solid state forms of ripretinib
KR20220045189A (en) 2019-08-12 2022-04-12 데시페라 파마슈티칼스, 엘엘씨. How to treat gastrointestinal stromal tumors
TWI878335B (en) 2019-08-12 2025-04-01 美商迪賽孚爾製藥有限公司 Methods of treating gastrointestinal stromal tumors
SMT202400484T1 (en) 2019-12-30 2025-01-14 Deciphera Pharmaceuticals Llc COMPOSITIONS OF 1-(4-BROMO-5-(1-ETHYL-7-(METHYLAMINO)-2-OXO-1,2-DIHYDRO-1,6-NAPHTHYRIDIN-3-YL)-2-FLUOROPHENYL)-3-PHENYLUREA
SMT202300467T1 (en) 2019-12-30 2024-01-10 Deciphera Pharmaceuticals Llc Amorphous kinase inhibitor formulations and methods of use thereof
US11779572B1 (en) 2022-09-02 2023-10-10 Deciphera Pharmaceuticals, Llc Methods of treating gastrointestinal stromal tumors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993004170A1 (en) * 1991-08-23 1993-03-04 The United States Of America Represented By The Secretary, Department Of Health And Human Services Raf protein kinase therapeutics

Also Published As

Publication number Publication date
WO1998022103A1 (en) 1998-05-28
ZA9710314B (en) 1998-05-18
AU4956297A (en) 1998-06-10
CA2267782A1 (en) 1998-05-28
JP2001504478A (en) 2001-04-03
NO992336D0 (en) 1999-05-14
EP0941084A1 (en) 1999-09-15
NO992336L (en) 1999-05-14

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