NO179869C - Fremgangsmåte til fremstilling av karbapenem-derivater, samt 4-substituerte azetidinoner som anvendes som mellomprodukter i fremgangsmåten - Google Patents

Fremgangsmåte til fremstilling av karbapenem-derivater, samt 4-substituerte azetidinoner som anvendes som mellomprodukter i fremgangsmåten

Info

Publication number: NO179869C
Authority: NO; Norway
Prior art keywords: intermediates; preparation; well; substituted azetidinones; carbapenem derivatives
Prior art date: 1991-03-20

Application number

NO921097A

Other languages

English (en)

Norwegian (no)

Other versions

NO179869B (no

NO921097L (no

NO921097D0 (no

Inventor

Gregg Brian Feigelson

William V Curran

Carl Bernard Ziegler

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-20

Filing date

1992-03-19

Publication date

1997-01-02

1992-03-19 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1992-03-19 Publication of NO921097D0 publication Critical patent/NO921097D0/no

1992-09-21 Publication of NO921097L publication Critical patent/NO921097L/no

1996-04-26 Priority to NO961702A priority Critical patent/NO300265B1/no

1996-09-23 Publication of NO179869B publication Critical patent/NO179869B/no

1997-01-02 Publication of NO179869C publication Critical patent/NO179869C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO921097A 1991-03-20 1992-03-19 Fremgangsmåte til fremstilling av karbapenem-derivater, samt 4-substituerte azetidinoner som anvendes som mellomprodukter i fremgangsmåten NO179869C (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO961702A NO300265B1 (no)	1991-03-20	1996-04-26	Fremgangsmåte for fremstilling av 4-substituerte azetidinoner

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/672,496 US5189158A (en)	1991-03-20	1991-03-20	4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them

Publications (4)

Publication Number	Publication Date
NO921097D0 NO921097D0 (no)	1992-03-19
NO921097L NO921097L (no)	1992-09-21
NO179869B NO179869B (no)	1996-09-23
NO179869C true NO179869C (no)	1997-01-02

Family

ID=24698802

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO921097A NO179869C (no)	1991-03-20	1992-03-19	Fremgangsmåte til fremstilling av karbapenem-derivater, samt 4-substituerte azetidinoner som anvendes som mellomprodukter i fremgangsmåten

Country Status (22)

Country	Link
US (1)	US5189158A (sk)
EP (1)	EP0504612B1 (sk)
JP (1)	JPH05125041A (sk)
KR (1)	KR920018020A (sk)
CN (2)	CN1065061A (sk)
AT (1)	ATE162518T1 (sk)
AU (1)	AU646934B2 (sk)
CA (1)	CA2063326A1 (sk)
CZ (1)	CZ284112B6 (sk)
DE (1)	DE69224093T2 (sk)
DK (1)	DK0504612T3 (sk)
ES (1)	ES2113383T3 (sk)
FI (1)	FI921179A (sk)
GR (1)	GR3026388T3 (sk)
HU (2)	HUT61522A (sk)
IE (1)	IE920870A1 (sk)
IL (1)	IL101293A0 (sk)
NO (1)	NO179869C (sk)
NZ (1)	NZ242026A (sk)
PL (4)	PL172298B1 (sk)
SG (1)	SG47727A1 (sk)
SK (1)	SK278789B6 (sk)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI96311C (fi) *	1989-12-04	1996-06-10	Squibb Bristol Myers Co	Menetelmä farmaseuttisesti käyttökelpoisten 6-(1-hydroksietyyli)-3-(substituoitu tio)-7-okso-1-atsabisyklo/3.2.0/hept-2-eeni-2-karboksyylihappojohdannaisten valmistamiseksi
US5371215A (en) *	1991-03-20	1994-12-06	American Cyanamid Company	4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
US5288888A (en) *	1993-04-28	1994-02-22	American Cyanamid Company	Process for the synthesis of acetic acid, (dimethoxyphosphinyl) [[1,1-dimethylethyl)dimethylsilyl]-oxy]-, (4-nitrophenyl) methyl ester
US5496816A (en) *	1994-03-14	1996-03-05	Merck & Co., Inc.	Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
US6916850B2 (en) *	2001-05-03	2005-07-12	Galileo Pharmaceuticals, Inc.	Pyruvate derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5055573A (en) *	1976-11-19	1991-10-08	Merck & Co., Inc.	Process for preparing 1-carba-2-penem-3-carboxylic acid
US4174316A (en) *	1978-08-14	1979-11-13	Merck & Co., Inc.	4-Iodomethylazetidin-2-one
US4350631A (en) *	1980-12-18	1982-09-21	Merck & Co., Inc.	6- and 4-Substituted-1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylates
EP0089139A2 (en) *	1982-03-16	1983-09-21	Beecham Group Plc	Antibiotics, their preparation and use
CA1283906C (en) *	1983-05-09	1991-05-07	Makoto Sunagawa	.beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
GB8804058D0 (en) *	1988-02-22	1988-03-23	Fujisawa Pharmaceutical Co	3-alkenyl-1-azabicyclo(3 2 0)hept-2-ene-2-carboxylic acid compounds
JPH03120280A (ja) *	1989-10-03	1991-05-22	Shionogi & Co Ltd	ハロメチルカルバペネム化合物の製法
US5068232A (en) *	1990-04-10	1991-11-26	American Cyanamid Company	Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
US5051502A (en) *	1990-06-06	1991-09-24	University Of Notre Dame Du Lac	Rhodium catalyzed cyclization process for bicyclic β-lactams

1991
- 1991-03-20 US US07/672,496 patent/US5189158A/en not_active Expired - Fee Related
1992
- 1992-02-21 DK DK92102925T patent/DK0504612T3/da active
- 1992-02-21 SG SG1996004077A patent/SG47727A1/en unknown
- 1992-02-21 ES ES92102925T patent/ES2113383T3/es not_active Expired - Lifetime
- 1992-02-21 AT AT92102925T patent/ATE162518T1/de not_active IP Right Cessation
- 1992-02-21 EP EP92102925A patent/EP0504612B1/en not_active Expired - Lifetime
- 1992-02-21 DE DE69224093T patent/DE69224093T2/de not_active Expired - Fee Related
- 1992-03-14 PL PL92309929A patent/PL172298B1/pl unknown
- 1992-03-14 PL PL92309930A patent/PL172378B1/pl unknown
- 1992-03-18 CA CA002063326A patent/CA2063326A1/en not_active Abandoned
- 1992-03-18 NZ NZ242026A patent/NZ242026A/en unknown
- 1992-03-18 CN CN92101876A patent/CN1065061A/zh active Pending
- 1992-03-19 HU HU9200917A patent/HUT61522A/hu unknown
- 1992-03-19 HU HU9203677A patent/HU9203677D0/hu unknown
- 1992-03-19 PL PL92309928A patent/PL171733B1/pl unknown
- 1992-03-19 SK SK833-92A patent/SK278789B6/sk unknown
- 1992-03-19 NO NO921097A patent/NO179869C/no unknown
- 1992-03-19 KR KR1019920004535A patent/KR920018020A/ko active IP Right Grant
- 1992-03-19 IE IE087092A patent/IE920870A1/en not_active Application Discontinuation
- 1992-03-19 AU AU13013/92A patent/AU646934B2/en not_active Ceased
- 1992-03-19 FI FI921179A patent/FI921179A/fi not_active Application Discontinuation
- 1992-03-19 JP JP4092293A patent/JPH05125041A/ja active Pending
- 1992-03-19 CZ CS92833A patent/CZ284112B6/cs not_active IP Right Cessation
- 1992-03-19 PL PL92293902A patent/PL171202B1/pl unknown
- 1992-03-19 IL IL101293A patent/IL101293A0/xx not_active IP Right Cessation
1996
- 1996-12-09 CN CN96123106A patent/CN1166489A/zh active Pending
1998
- 1998-03-17 GR GR980400585T patent/GR3026388T3/el unknown

Also Published As

Publication number	Publication date
PL293902A1 (en)	1993-10-18
US5189158A (en)	1993-02-23
PL172378B1 (pl)	1997-09-30
NO179869B (no)	1996-09-23
JPH05125041A (ja)	1993-05-21
CZ284112B6 (cs)	1998-08-12
CN1166489A (zh)	1997-12-03
NO921097L (no)	1992-09-21
AU1301392A (en)	1992-09-24
PL171733B1 (pl)	1997-06-30
SK278789B6 (sk)	1998-02-04
IE920870A1 (en)	1992-09-23
DE69224093T2 (de)	1998-05-07
EP0504612A2 (en)	1992-09-23
CS83392A3 (en)	1992-10-14
EP0504612A3 (en)	1993-01-27
HU9203677D0 (en)	1993-03-29
DE69224093D1 (de)	1998-02-26
HU9200917D0 (en)	1992-05-28
KR920018020A (ko)	1992-10-21
NO921097D0 (no)	1992-03-19
FI921179A0 (fi)	1992-03-19
ATE162518T1 (de)	1998-02-15
DK0504612T3 (da)	1998-09-21
CA2063326A1 (en)	1992-09-21
AU646934B2 (en)	1994-03-10
IL101293A0 (en)	1992-11-15
NZ242026A (en)	1994-10-26
PL172298B1 (pl)	1997-09-30
PL171202B1 (pl)	1997-03-28
GR3026388T3 (en)	1998-06-30
CN1065061A (zh)	1992-10-07
EP0504612B1 (en)	1998-01-21
FI921179A (fi)	1992-09-21
HUT61522A (en)	1993-01-28
SG47727A1 (en)	1998-04-17
ES2113383T3 (es)	1998-05-01

Publication	Publication Date	Title
IL66596A0 (en)	1982-12-31	Antihypertensive substituted n-alkanoylheterocyclic carboxylic acid derivatives,compositions containing them and methods for their use
AU678814B2 (en)	1997-06-12	Benzofuranyl- and -thiophenyl-alkanecarboxyclic acid derivatives
DE3580803D1 (de)	1991-01-17	Neue zwischenprodukte und verfahren zur herstellung von 3-acylamino-1-hydroxy-2-azetidinonen.
ATE254594T1 (de)	2003-12-15	Verbindungen verwendbar als zwischenprodukte zur herstellung von piperidinderivate
FI906438A (fi)	1991-06-30	Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
NO893205D0 (no)	1989-08-09	Kjemiske forbindelser.
DE69327567D1 (de)	2000-02-17	Verfahren zur Herstellung von Alanylglutamin
DK0503453T3 (da)	2001-07-16	Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde
NO894349L (no)	1990-05-03	Tienopyridin-type mevalonolaktoner.
NO179869C (no)	1997-01-02	Fremgangsmåte til fremstilling av karbapenem-derivater, samt 4-substituerte azetidinoner som anvendes som mellomprodukter i fremgangsmåten
NO308743B1 (no)	2000-10-23	FremgangsmÕte for fremstilling av N-acetyl- neuraminsyrederivater
PL238200A1 (en)	1985-02-13	Process for preparing novel penicillins
ATE56452T1 (de)	1990-09-15	Verfahren zur herstellung von penemderivaten.
DE3777464D1 (de)	1992-04-23	Fluorine enthaltende vitamin-d3-derivate und verfahren zu ihrer herstellung.
DK0399748T3 (da)	1996-02-12	Fremgangsmåde til fremstilling af 2-oxindol-1-carboxamider
ES2150479T3 (es)	2000-12-01	Derivados de psicofuranosa y psicopiranosa.
AU5509390A (en)	1990-10-04	Process for synthesizing beta-lactam compounds
PT82593B (pt)	1988-03-03	Processo de preparacao da oxadiazolil-imidazobenzodiazepina e das composicoes farmaceuticas que a contem
ATE35982T1 (de)	1988-08-15	Azetidinderivate.
ATE200674T1 (de)	2001-05-15	Herstellung von beta-lactamverbindungen und zwischenprodukte
ATE151428T1 (de)	1997-04-15	Verfahren zur herstellung von 3- exomethylencephamsulfoxydderivate und zwischenverbindungen
NO304981B1 (no)	1999-03-15	FremgangsmÕte for fremstilling av karbapenem- og penemforbindelser, samt nye forbindelser involvert i fremgangsmÕten
AU2356384A (en)	1984-08-09	Imidazolyl-pyrazolyl methanone derivatives