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NO179354C - Nisin-sammensetning med forbedret bredspektret baktericidal aktivitet - Google Patents

Nisin-sammensetning med forbedret bredspektret baktericidal aktivitet

Info

Publication number
NO179354C
NO179354C NO895147A NO895147A NO179354C NO 179354 C NO179354 C NO 179354C NO 895147 A NO895147 A NO 895147A NO 895147 A NO895147 A NO 895147A NO 179354 C NO179354 C NO 179354C
Authority
NO
Norway
Prior art keywords
broad spectrum
bactericidal activity
spectrum bactericidal
enhanced broad
nisin
Prior art date
Application number
NO895147A
Other languages
English (en)
Norwegian (no)
Other versions
NO895147D0 (no
NO179354B (no
NO895147L (no
Inventor
Peter Blackburn
June Polak
Sara-Ann Gusik
Stephen D Rubino
Original Assignee
Applied Microbiology Inc
New York Health Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CS896897A external-priority patent/CZ277995B6/cs
Application filed by Applied Microbiology Inc, New York Health Res Inst filed Critical Applied Microbiology Inc
Publication of NO895147D0 publication Critical patent/NO895147D0/no
Publication of NO895147L publication Critical patent/NO895147L/no
Publication of NO179354B publication Critical patent/NO179354B/no
Publication of NO179354C publication Critical patent/NO179354C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
    • A01N63/28—Streptomyces
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B11/00—Preservation of milk or dairy products
    • A23B11/60—Preservation of cheese or cheese preparations
    • A23B11/65—Preservation of cheese or cheese preparations by addition of preservatives
    • A23B11/67—Preservation of cheese or cheese preparations by addition of preservatives of antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/7295—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/767—Organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/783—Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/158—Milk preparations; Milk powder or milk powder preparations containing additives containing vitamins or antibiotics
    • A23C9/1585—Antibiotics; Bacteriocins; Fungicides from microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Dairy Products (AREA)
NO895147A 1988-06-22 1989-12-20 Nisin-sammensetning med forbedret bredspektret baktericidal aktivitet NO179354C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20986188A 1988-06-22 1988-06-22
US31762689A 1989-03-01 1989-03-01
PCT/US1989/002625 WO1989012399A1 (en) 1988-06-22 1989-06-16 Nisin compositions for use as enhanced, broad range bactericides
CS896897A CZ277995B6 (cs) 1988-06-22 1989-12-06 Bakteriocinový přípravek

Publications (4)

Publication Number Publication Date
NO895147D0 NO895147D0 (no) 1989-12-20
NO895147L NO895147L (no) 1989-12-28
NO179354B NO179354B (no) 1996-06-17
NO179354C true NO179354C (no) 1996-09-25

Family

ID=27179536

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895147A NO179354C (no) 1988-06-22 1989-12-20 Nisin-sammensetning med forbedret bredspektret baktericidal aktivitet

Country Status (14)

Country Link
EP (2) EP0545911B1 (fi)
JP (1) JPH089525B2 (fi)
AT (2) ATE142504T1 (fi)
AU (1) AU631803B2 (fi)
DD (1) DD301912A9 (fi)
DE (2) DE68927189T2 (fi)
DK (1) DK171069B1 (fi)
FI (1) FI98880C (fi)
HU (1) HU204980B (fi)
IE (2) IE77643B1 (fi)
IL (1) IL90700A (fi)
NO (1) NO179354C (fi)
NZ (1) NZ229674A (fi)
WO (1) WO1989012399A1 (fi)

Families Citing this family (60)

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US5304540A (en) * 1988-06-22 1994-04-19 Applied Microbiology, Inc. Pharmaceutical bacteriocin compositions and methods for using the same
US5334582A (en) * 1988-06-22 1994-08-02 Applied Microbiology, Inc. Pharmaceutical bacteriocin compositions and methods for using the same
US5573797A (en) * 1989-02-21 1996-11-12 Viskase Corporation Film and method for surface treatment of foodstuffs with antimicrobial compositions
US5573800A (en) * 1989-02-21 1996-11-12 Viskase Corporation Antimicrobial composition for surface treatment of foodstuffs
US5573801A (en) * 1989-02-21 1996-11-12 Viskase Corporation Surface treatment of foodstuffs with antimicrobial compositions
NZ244737A (en) * 1989-02-21 1993-09-27 Viskase Corp Food packaging polymeric film containing antibiotic material; method of treating foodstuff and food casing therefor
NO911341L (no) * 1990-04-20 1991-10-21 Haarmann & Reimer Corp Fremgangsmaate for aa drepe gram-negative bakterier.
EP0453972B1 (en) * 1990-04-23 1994-02-09 HAARMANN & REIMER CORP. Use of lanthionines for control of post-processing contamination in food
CA2043463A1 (en) * 1990-06-13 1991-12-14 Nancy L. Bycroft Synergistic antimicrobial compositions
AU2591592A (en) * 1991-09-05 1993-04-05 Haarmann & Reimer Corp. Composition and method of attenuation of ionic strength inhibition of lantibiotics
GB9126686D0 (en) * 1991-12-17 1992-02-12 Smithkline Beecham Plc Novel compositions
US5342612A (en) * 1991-12-20 1994-08-30 American Cyanamid Company Compositions for the treatment of mammalian diseases
IL104364A (en) * 1992-01-17 1997-09-30 Applied Microbiology Pharmaceutical compositions containing bacteriocins
DE4229707A1 (de) * 1992-09-05 1994-03-10 Beiersdorf Ag Germicide Wirkstoffkombinationen
EP0659068B1 (en) * 1992-09-10 1996-12-04 Sara Lee/DE N.V. Mouth-care products with anti-bacterial activity
CA2148255A1 (en) * 1992-10-29 1994-05-11 Rainer Denecke Preparation for therapeutic and especially prophylactic treatment of digestive tract disorders
DE4307352A1 (de) * 1992-10-29 1994-05-05 Denecke Rainer Dr Med Vet Präparat zur Therapie und insbesondere Prophylaxe von Erkrankungen des Verdauungstraktes
GB9224598D0 (en) * 1992-11-24 1993-01-13 Smithkline Beecham Plc Novel compositions
IL107887A (en) * 1992-12-08 2003-07-06 Ambi Inc Stabilized lanthionine containing bacteriocin compositions
US5368845A (en) * 1993-01-07 1994-11-29 Colgate Palmolive Company Oral composition
WO1994018845A1 (en) * 1993-02-17 1994-09-01 Michael Foods, Inc. Method of treating liquid whole egg products
US5512269A (en) * 1993-06-09 1996-04-30 Burroughs Wellcome, Co. Method of treating retained pulmonary secretions
JP3040282B2 (ja) * 1993-07-30 2000-05-15 アサマ化成株式会社 食品用保存剤
JP3042573B2 (ja) * 1993-07-30 2000-05-15 アサマ化成株式会社 食品用保存剤
JP3040295B2 (ja) * 1993-10-27 2000-05-15 アサマ化成株式会社 食品用保存剤
JP3040294B2 (ja) * 1993-10-27 2000-05-15 アサマ化成株式会社 食品用保存剤
US5883074A (en) * 1995-02-08 1999-03-16 Microcide Pharmaceuticals, Inc. Potentiators of antibacterial agents
GB9510719D0 (en) * 1995-05-26 1995-07-19 Smithkline Beecham Plc Novel compositions
US5762948A (en) * 1995-06-07 1998-06-09 Ambi Inc. Moist bacteriocin disinfectant wipes and methods of using the same
GB9517113D0 (en) * 1995-08-21 1995-10-25 Smithkline Beecham Plc Novel compositions
ZA967950B (en) * 1995-09-20 1997-04-07 Applied Microbiology Inc Nisin compositions to prevent the promotion of tooth decay by suppressing formation of acid from foods by oral bacteria
US5804549A (en) * 1996-01-05 1998-09-08 Ambi Inc. Compositions with activity against helicobacter
WO1998004143A2 (en) * 1996-07-26 1998-02-05 The Dow Chemical Company A process for the decontamination of meats
CA2265521C (en) * 1996-09-13 2009-06-09 Clemson University Anti-bacterial composition for treating acne
US6221847B1 (en) 1996-09-13 2001-04-24 Clemson University Composition and method for treating bacterial infection
WO1999002049A1 (en) * 1997-07-10 1999-01-21 Kabushiki Kaisha Yamakoh Bactericidal agents for treating plants and process for producing the same
US6015832A (en) * 1997-12-31 2000-01-18 The Regents Of The University Of Michigan Methods of inactivating bacteria including bacterial spores
AUPP146598A0 (en) * 1998-01-21 1998-02-12 Health And Hygiene International Pty Ltd Fruit and vegetable wash
AU2001227076A1 (en) * 2000-03-28 2001-10-08 Junichi Abe Bacterial growth regulators or inhibitors with the use of 1,5-d-anhydrofructose
US6518252B2 (en) * 2000-09-20 2003-02-11 University Of Georgia Research Foundation, Inc. Method of treating aquatic animals with an antimicrobial agent and chelating agent
FR2847165A1 (fr) * 2002-11-15 2004-05-21 Jean Noel Thorel Utilisation de la nisine dans des formulations cosmetiques et/ou pharmaceutiques a usage topique
AU2003296937A1 (en) * 2002-12-10 2004-06-30 Biosynexus Incorporated Topical anti-infective formulations
FR2855181A1 (fr) * 2003-05-23 2004-11-26 Rhodia Chimie Sa Composition detergente a activite anti-microbienne
JP4926707B2 (ja) * 2003-08-22 2012-05-09 ダニスコ エイ／エス 封入化抗菌材料
GB2388581A (en) 2003-08-22 2003-11-19 Danisco Coated aqueous beads
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US20050058673A1 (en) 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
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US7211287B2 (en) 2004-06-24 2007-05-01 Cargill, Incorporated Egg Products
CA2599667C (en) 2005-03-10 2014-12-16 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxy carboxylic acids
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EP2206506A1 (en) * 2008-12-18 2010-07-14 Bracco Imaging S.p.A Probiotic formulations
KR101352795B1 (ko) * 2010-02-26 2014-02-17 주식회사 나이벡 치아의 접합능을 향상시키기 위한 치과용 클린저 조성물
PL236330B1 (pl) 2010-06-01 2020-12-28 Univ Przyrodniczy W Poznaniu Dodatek paszowy o właściwościach przeciwdrobnoustrojowych, mieszanka paszowa, zastosowanie dodatku paszowego do wytwarzania mieszanki paszowej
JP5894457B2 (ja) * 2012-02-22 2016-03-30 株式会社Adeka ペプチド含有抗菌性組成物
WO2014031842A1 (en) 2012-08-22 2014-02-27 Kraft Foods Group Brands Llc Processed cheese with cultured dairy components and method of manufacturing
BR112015007099A2 (pt) * 2012-10-05 2017-07-04 Delaval Holding Ab uso de composições contendo iodo para redução de patógeno durante processamento de alimento
CN104918494A (zh) * 2012-11-14 2015-09-16 生态友好研究所株式会社 抗菌用组合物
US11304888B2 (en) 2019-04-29 2022-04-19 Sunstar Americas, Inc. Oral care composition
JP2023068430A (ja) 2021-11-02 2023-05-17 住友化学株式会社 抗菌ペプチド

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GB738655A (en) * 1952-05-09 1955-10-19 Aplin & Barrett Ltd A dry nisin preparation
DE3701835A1 (de) * 1987-01-23 1988-08-04 Hoechst Ag Bakterienlysierendes enzymprodukt aus streptomyceten, seine herstellung und seine verwendung zur konservierung von kaese
ES2063051T3 (es) * 1987-12-24 1995-01-01 Zeneca Ltd Cepas bacterianas.
CA2005122A1 (en) * 1988-12-21 1991-05-16 Daniel J. Monticello Control of microbial growth with nisin/lysozyme formulations
NZ244737A (en) * 1989-02-21 1993-09-27 Viskase Corp Food packaging polymeric film containing antibiotic material; method of treating foodstuff and food casing therefor

Also Published As

Publication number Publication date
AU3843089A (en) 1990-01-12
NO895147D0 (no) 1989-12-20
DD301912A9 (de) 1994-07-14
DE68913189T2 (de) 1994-05-19
WO1989012399A1 (en) 1989-12-28
ATE101490T1 (de) 1994-03-15
HUT53795A (en) 1990-12-28
ATE142504T1 (de) 1996-09-15
FI98880C (fi) 1997-09-10
EP0545911A2 (en) 1993-06-09
DK171069B1 (da) 1996-05-28
JPH03500051A (ja) 1991-01-10
IE77643B1 (en) 1997-12-31
IE940624L (en) 1989-12-22
NZ229674A (en) 1992-12-23
IE63998B1 (en) 1995-06-28
FI98880B (fi) 1997-05-30
EP0545911A3 (en) 1993-07-28
IL90700A (en) 1994-06-24
EP0545911B1 (en) 1996-09-11
EP0382814B1 (en) 1994-02-16
NO179354B (no) 1996-06-17
JPH089525B2 (ja) 1996-01-31
IL90700A0 (en) 1990-01-18
FI895878A0 (fi) 1989-12-08
EP0382814A1 (en) 1990-08-22
HU204980B (en) 1992-03-30
DE68913189D1 (de) 1994-03-24
AU631803B2 (en) 1992-12-10
DE68927189D1 (de) 1996-10-17
DK45690A (da) 1990-02-21
DE68927189T2 (de) 1997-01-30
IE892015L (en) 1989-12-22
DK45690D0 (da) 1990-02-21
HU893794D0 (en) 1990-06-28
NO895147L (no) 1989-12-28

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