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NO175939C - Analogifremgangsmåte for fremstilling av terapeutisk aktiv N1-(1,2-cis-2-halogencyklopropyl)-substituerte pyridonkarboksylsyrederivater, eller et farmasöytisk akseptabelt salt derav, eventuelt i en stereoisomerisk form - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktiv N1-(1,2-cis-2-halogencyklopropyl)-substituerte pyridonkarboksylsyrederivater, eller et farmasöytisk akseptabelt salt derav, eventuelt i en stereoisomerisk form

Info

Publication number
NO175939C
NO175939C NO891698A NO891698A NO175939C NO 175939 C NO175939 C NO 175939C NO 891698 A NO891698 A NO 891698A NO 891698 A NO891698 A NO 891698A NO 175939 C NO175939 C NO 175939C
Authority
NO
Norway
Prior art keywords
preparation
therapeutically active
analogous process
halogenocydopropyl
cis
Prior art date
Application number
NO891698A
Other languages
English (en)
Other versions
NO891698L (no
NO891698D0 (no
NO175939B (no
Inventor
Isao Hayakawa
Yoichi Kimura
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO891698D0 publication Critical patent/NO891698D0/no
Publication of NO891698L publication Critical patent/NO891698L/no
Publication of NO175939B publication Critical patent/NO175939B/no
Publication of NO175939C publication Critical patent/NO175939C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO891698A 1988-04-27 1989-04-25 Analogifremgangsmåte for fremstilling av terapeutisk aktiv N1-(1,2-cis-2-halogencyklopropyl)-substituerte pyridonkarboksylsyrederivater, eller et farmasöytisk akseptabelt salt derav, eventuelt i en stereoisomerisk form NO175939C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10462588 1988-04-27
JP29698488 1988-11-24

Publications (4)

Publication Number Publication Date
NO891698D0 NO891698D0 (no) 1989-04-25
NO891698L NO891698L (no) 1989-10-30
NO175939B NO175939B (no) 1994-09-26
NO175939C true NO175939C (no) 1995-01-04

Family

ID=26445063

Family Applications (1)

Application Number Title Priority Date Filing Date
NO891698A NO175939C (no) 1988-04-27 1989-04-25 Analogifremgangsmåte for fremstilling av terapeutisk aktiv N1-(1,2-cis-2-halogencyklopropyl)-substituerte pyridonkarboksylsyrederivater, eller et farmasöytisk akseptabelt salt derav, eventuelt i en stereoisomerisk form

Country Status (25)

Country Link
US (4) US5587386A (no)
EP (1) EP0341493B1 (no)
JP (5) JP2714597B2 (no)
KR (1) KR0184614B1 (no)
CN (1) CN1033751C (no)
AT (1) ATE182145T1 (no)
AU (1) AU625414B2 (no)
BG (1) BG61122B2 (no)
CA (1) CA1340801C (no)
DE (1) DE68929030T2 (no)
DK (1) DK175467B1 (no)
ES (1) ES2135372T3 (no)
FI (1) FI96947C (no)
GR (1) GR3031365T3 (no)
HU (1) HU211136A9 (no)
IL (1) IL90062A (no)
LV (1) LV10092B (no)
MY (1) MY105136A (no)
NO (1) NO175939C (no)
NZ (1) NZ228893A (no)
PT (1) PT90377B (no)
RU (1) RU2075475C1 (no)
SG (1) SG48036A1 (no)
UA (1) UA29378C2 (no)
YU (1) YU48432B (no)

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AU757805B2 (en) 1998-11-24 2003-03-06 Daiichi Pharmaceutical Co., Ltd. Cycloalkyl-substituted aminomethylpyrrolidine derivatives
CN1258531C (zh) * 1999-03-10 2006-06-07 第一制药株式会社 芳香族取代基取代的氨基甲基吡咯烷衍生物
KR100768034B1 (ko) 1999-03-17 2007-10-17 다이이찌 세이야꾸 가부시기가이샤 의약 조성물
KR100817425B1 (ko) * 2000-02-09 2008-03-27 다이이찌 세이야꾸 가부시기가이샤 피리돈카복실산류를 유효성분으로 하는 항항산균제
CN1432008A (zh) * 2000-03-31 2003-07-23 第一制药株式会社 喹诺酮羧酸衍生物
ES2305065T3 (es) * 2000-04-24 2008-11-01 Daiichi Sankyo Company, Limited Preparacion liquida estable que contiene sitafloxacina.
CN1214792C (zh) * 2000-08-08 2005-08-17 第一制药株式会社 吸收性很好的固体制剂
KR101041277B1 (ko) * 2002-05-17 2011-06-14 다이이찌 세이야꾸 가부시기가이샤 퀴놀론카르복실산 유도체의 제조방법
ATE488489T1 (de) * 2003-01-07 2010-12-15 Daiichi Sankyo Co Ltd Verfahren zur reduktiven deshalogenierung
US7085154B2 (en) * 2003-06-03 2006-08-01 Samsung Electronics Co., Ltd. Device and method for pulse width control in a phase change memory device
WO2005111015A1 (ja) 2004-05-13 2005-11-24 Daiichi Pharmaceutical Co., Ltd. 置換ピロリジン誘導体
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
RU2420524C2 (ru) * 2005-05-19 2011-06-10 Дайити Санкио Компани, Лимитед Производные три- или тетра-замещенного-3-аминопирролидина
JP5063032B2 (ja) * 2005-05-19 2012-10-31 第一三共株式会社 トリ−、テトラ−置換−３−アミノピロリジン誘導体
JP5017101B2 (ja) * 2005-05-20 2012-09-05 第一三共株式会社 不斉四置換炭素原子含有化合物の製法
US7977346B2 (en) 2006-01-17 2011-07-12 Guoqing Paul Chen Spiro compounds and methods of use
TWI386401B (zh) * 2006-03-27 2013-02-21 Daiichi Seiyaku Co 醫藥用水合物
PL2097400T3 (pl) 2007-01-05 2013-11-29 Daiichi Sankyo Co Ltd Skondensowane podstawione pochodne aminopirolidyny
ES2401415T3 (es) 2008-07-11 2013-04-19 Sumitomo Chemical Company, Limited Procedimiento para producir el ácido (1S, 2R)-2-cloro-2-fluorociclopropanocarboxílico
FR2961207B1 (fr) * 2010-06-09 2013-01-18 Oreal Utilisation d'un derive de 4- carboxy 2-pyrrolidinone comme solvant dans les compositions cosmetiques ; compositions cosmetiques les contenant ; nouveaux composes
CN103467448B (zh) * 2013-09-18 2015-04-15 浙江司太立制药股份有限公司 7-(3-氨基-4-烷氧亚胺基-1-哌啶基)-1-[(1r,2s)-2-氟环丙基]喹诺酮羧酸类化合物及其制备方法
EP2957561A1 (en) * 2014-06-18 2015-12-23 Université Paris 6 Pierre et Marie Curie UPMC Novel fluoroquinolones and use thereof to treat bacterial infections
CN105330590B (zh) * 2015-10-15 2018-09-25 广州市朗启医药科技有限责任公司 西他沙星五元环侧链中间体的制备方法
CN109912504B (zh) * 2019-04-04 2020-11-10 山东省联合农药工业有限公司 一种喹啉羧酸类化合物及其制备方法与用途

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Also Published As

Publication number Publication date
JP2917010B2 (ja) 1999-07-12
JPH07300416A (ja) 1995-11-14
NO891698L (no) 1989-10-30
DK205789D0 (da) 1989-04-27
USRE41149E1 (en) 2010-02-23
JPH11124380A (ja) 1999-05-11
HK1002108A1 (en) 1998-07-31
CA1340801C (en) 1999-10-26
YU48432B (sh) 1998-07-10
US6031102A (en) 2000-02-29
JP2714597B2 (ja) 1998-02-16
ATE182145T1 (de) 1999-07-15
NZ228893A (en) 1990-06-26
DK175467B1 (da) 2004-11-01
US5587386A (en) 1996-12-24
IL90062A0 (en) 1989-12-15
KR900016205A (ko) 1990-11-12
JPH02231475A (ja) 1990-09-13
FI891980A7 (fi) 1989-10-28
DE68929030D1 (de) 1999-08-19
JP2903292B2 (ja) 1999-06-07
US5767127A (en) 1998-06-16
IL90062A (en) 1994-10-07
FI96947B (fi) 1996-06-14
CN1033751C (zh) 1997-01-08
ES2135372T3 (es) 1999-11-01
FI96947C (fi) 1996-09-25
EP0341493A2 (en) 1989-11-15
NO891698D0 (no) 1989-04-25
HU211136A9 (en) 1995-10-30
CN1037507A (zh) 1989-11-29
KR0184614B1 (ko) 1999-05-01
NO175939B (no) 1994-09-26
AU625414B2 (en) 1992-07-09
SG48036A1 (en) 1998-04-17
YU87589A (en) 1990-12-31
GR3031365T3 (en) 2000-01-31
BG61122B2 (bg) 1996-11-29
PT90377A (pt) 1989-11-10
MY105136A (en) 1994-08-30
EP0341493B1 (en) 1999-07-14
LV10092B (en) 1995-02-20
PT90377B (pt) 1994-09-30
DK205789A (da) 1989-10-28
EP0341493A3 (en) 1990-12-19
DE68929030T2 (de) 2000-03-23
RU2075475C1 (ru) 1997-03-20
FI891980A0 (fi) 1989-04-26
JPH11124367A (ja) 1999-05-11
JPH1067779A (ja) 1998-03-10
UA29378C2 (uk) 2000-11-15
AU3370289A (en) 1989-11-02

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